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Search Results for " sost "

Targets Recommended: P450

10

抑制剂 & 化合物

5

天然产物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T77627	Opevesostat ODM208,ODM-208	P450	Metabolism
	Opevesostat (ODM-208) 是一种裂解酶 (CYP11A1) 抑制剂（裂解酶裂解胆固醇侧链）。
T33647L	Nesosteine Lithium Nesosteine Lithium(84233-61-4 Free baes)	Others	Others
	Nesosteine Lithium 是一种新型的粘液调节剂，对豚鼠 Herxheimer 微休克具有抑制作用且抑制卵清蛋白诱导的组胺在致敏动物气管中的释放。Nesosteine Lithium 能够保护致敏动物免受卵清蛋白诱导的支气管痉挛但对组胺和乙酰胆碱诱导的支气管痉挛无效。
T41032	Lysostaphin	Antibacterial	Microbiology/Virology
	Lysostaphin是一种具有强大抗葡萄球菌活性的化合物，通过三种不同的酶展现其酶促活性：glycylglycine endopeptidase、endo-β-N-acetyl glucosamidase和N-acetyl muramyl-L-alanine amidase。
T83171	Adamtsostatin 18
	Adamtsostatin 18，一种源自含有I型血小板反应蛋白基序的抗血管生成肽，能够抑制细胞迁移和增殖。
T31481	Diisostearyl adipate	Others	Others
	Diisostearyl adipate can be used for skin care.
T125532	Nitrosostromelin	Others	Others
	Nitrosostromelin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125532。
T33647	Nesosteine	Others	Others
	Nesosteine is a mucoregulatory agent.
T83170	Adamtsostatin 4
	Adamtsostatin 4为一种具有抗血管生成特性的肽类化合物，主要应用于抗血管生成相关研究领域。
T23153	Physostigmine hemisulfate	Others	Others
	cholinesterase inhibitor
T78278	Blosozumab
	Blosozumab (LY2541546)为针对人sclerostin (SOST)的单克隆抗体。它能促进骨生成，同时抑制骨吸收，可应用于骨质疏松症相关研究。

化合物

Cat.No: T77627

Synonym: ODM208,ODM-208

Target: P450

Nesosteine Lithium

Cat.No: T33647L

Synonym: Nesosteine Lithium(84233-61-4 Free baes)

Target: Others

Cat.No: T41032

Target: Antibacterial

Adamtsostatin 18

Cat.No: T83171

Diisostearyl adipate

Cat.No: T31481

Target: Others

Nitrosostromelin

Cat.No: T125532

Target: Others

Cat.No: T33647

Target: Others

Adamtsostatin 4

Cat.No: T83170

Physostigmine hemisulfate

Cat.No: T23153

Target: Others

Cat.No: T78278

Cat. No.	Product Name	Target	Signaling Pathways
T3332	Isosteviol 异甜菊醇,(-)-Isosteviol	IL Receptor; Potassium Channel; TNF; NF-κB; Reactive Oxygen Species; COX; Topoisomerase	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
	Isosteviol ((-)-Isosteviol) 是一种常见的天然甜味剂，属于四环二萜糖苷，是甜菊糖苷通过酸催化水解产生的。它抑制 DNA 聚合酶和 DNA 拓扑异构酶，具有抗菌、抗癌和抗结核作用。
T0130	Physostigmine Salicylate 水杨酸依色林,水杨酸毒扁豆碱	AChR; AChE	Neuroscience
	Physostigmine salicylate 是一种可逆的乙酰胆碱酯酶抑制剂，也一种是抗胆碱能中毒的解毒剂。它可透过血脑屏障并刺激中枢胆碱能神经传递。它能逆转阿尔茨海默病转基因小鼠的记忆缺陷。
TN6252	Isostephodeline
	Isostephodeline 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6252，CAS号为 56648-85-2。
T21438	Physostigmine Physostol,Antilirium,Eserine,毒扁豆碱,Esromiotin,Ezerin	Others	Others
	Physostigmine is a potent and reversible inhibitor of cholinesterase. It is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE).
T65262	Isostearic acid	Others	Others
	Isostearic acid 是一种天然产物，可用于生命科学领域的相关研究，其产品编号为 T65262。

天然产物

Cat.No: T3332

Synonym: 异甜菊醇,(-)-Isosteviol

Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase

Physostigmine Salicylate

Cat.No: T0130

Synonym: 水杨酸依色林,水杨酸毒扁豆碱

Target: AChR, AChE

Isostephodeline

Cat.No: TN6252

Cat.No: T21438

Synonym: Physostol,Antilirium,Eserine,毒扁豆碱,Esromiotin,Ezerin

Target: Others

Isostearic acid

Cat.No: T65262

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00925	SOST Protein, Human, Recombinant (His) VBCH,sclerostin,DAND6,CDD,SOST1	Human	HEK293 Cells
	SOST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPJ-01294	SOST Protein, Mouse, Recombinant (His) Sost,Sclerostin	Mouse	HEK293 Cells
	Sclerostin (SOST) is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. Cerberus/DAN family members are putative BMP antagonists, and include Dan, Cerberus, Gremlin, PRDC, and Caronte. While the overall sequence identity between members of the family is low, they have conserved spacing of six cysteine residues. Cerberus and Dan have an additional cysteine residue used for dimerization; however, SOST does not and is secreted as a monomer...
TMPH-02886	SOST Protein, Mouse, Recombinant (hFc) Sost,Sclerostin	Mouse	HEK293 Cells
	Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
TMPK-00102	SOST Protein, Human, Recombinant (His & Avi) VBCHsclerosteosis,SOST1,sclerostin,SOST,CD...	Human	HEK293 Cells
	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9BQB4-1.
TMPK-01293	SOST Protein, Cynomolgus, Recombinant (His) VBCH,SOST1,sclerostin,DAND6,SOST,CDD,VBCHs...	Cynomolgus	HEK293 Cells
	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 22.58 kDa and the accession number is XP_005584428.2.
TMPY-01633	SOST Protein, Rat, Recombinant (His) sclerostin	Rat	HEK293 Cells
	SOST Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23 kDa and the accession number is A6HJF6.
TMPK-00103	SOST Protein, Human, Recombinant (His & Avi), Biotinylated VBCH,DAND6,VBCHsclerosteosis,sclerostin,SOST1,CDD,<...	Human	HEK293 Cells
	SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9BQB4-1.
TMPY-05113	SOST Protein, Human, Recombinant (His), Biotinylated VBCH,SOST1,DAND6,sclerostin,CDD	Human	HEK293 Cells
	SOST Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
TMPH-03367	SOSTDC1 Protein, Rat, Recombinant (His & Myc) Sostdc1,Sclerostin domain-containing protein 1,Wnt-...	Rat	HEK293 Cells
	Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. SOSTDC1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 24.6 kDa and the accession number is Q642G2.
TMPH-02885	SOSTDC1 Protein, Mouse, Recombinant (His & Myc) Sclerostin-like protein,Sostdc1,Sclerostin domain-c...	Mouse	E. coli
	May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
TMPK-00739	LRP-5 Protein, Human, Recombinant (hFc) EVR1,BMND1,BMND1OPTA1,LRP5,LRP7,OPPG,EVR4,OPTA1,OPS,HBM,VBCH...	Human	HEK293 Cells
	A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that altered the function of the sclerostin (SOST) gene were also associated with altered human bone mass. Subsequent studies of LRP5 and sclerostin have provided important insights into the mechanisms by which these proteins regulate skeletal homeostasis. LRP-5 Protein, Human, Recomb...
TMPK-00740	LRP-5 Protein, Human, Recombinant (mFc) LRP7,EVR1,LR3VBCH2,HBM,LRP5,EVR4,VBCH2,OPS,BMND1OPTA1,LR3,OP...	Human	HEK293 Cells
	A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that altered the function of the sclerostin (SOST) gene were also associated with altered human bone mass. Subsequent studies of LRP5 and sclerostin have provided important insights into the mechanisms by which these proteins regulate skeletal homeostasis. LRP-5 Protein, Human, Recomb...

重组蛋白

SOST Protein, Human, Recombinant (His)

Cat.No: TMPY-00925

Species: Human

Expression System: HEK293 Cells

SOST Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01294

Species: Mouse

Expression System: HEK293 Cells

SOST Protein, Mouse, Recombinant (hFc)

Cat.No: TMPH-02886

Species: Mouse

Expression System: HEK293 Cells

SOST Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00102

Species: Human

Expression System: HEK293 Cells

SOST Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01293

Species: Cynomolgus

Expression System: HEK293 Cells

SOST Protein, Rat, Recombinant (His)

Cat.No: TMPY-01633

Species: Rat

Expression System: HEK293 Cells

SOST Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00103

Species: Human

Expression System: HEK293 Cells

SOST Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05113

Species: Human

Expression System: HEK293 Cells

SOSTDC1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03367

Species: Rat

Expression System: HEK293 Cells

SOSTDC1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02885

Species: Mouse

Expression System: E. coli

LRP-5 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00739

Species: Human

Expression System: HEK293 Cells

LRP-5 Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00740

Species: Human

Expression System: HEK293 Cells

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