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Search Results for " somatostatin , "

Targets Recommended: Others

125

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1035L	Cyclic somatostatin Acetate Somatostatin (sheep), monoacetate (salt),Cyclic somatostatin Acetate(38916-34-6 free base),Somatostatin-14,SRIF-14,monoacetate (salt)	Others	Others
	Cyclic somatostatin Acetate(38916-34-6(free base)) (Somatostatin-14) 是一种环状十四肽，可调节许多内分泌和神经系统功能。
TP1790L	Tyr-Somatostatin-14 acetate Tyr-Somatostatin-14 acetate(58100-03-1 free base)	Others	Others
	Tyr-Somatostatin-14 acetate(58100-03-1 free base) 是一种定制肽，可在 Somatostatin-14 中添加酪氨酸氨基酸。
TP2124L	Somatostatin 1-28 acetate Somatostatin 1-28 acetate(74315-46-1 Free base)	Somatostatin	GPCR/G Protein
	Somatostatin 1-28 acetate 在人源血浆中循环。血浆中约 46% 的总生长抑素样免疫反应性是由于 Somatostatin 1-28 acetate 所致。
TP1302L	Somatostatin acetate Somatostatin acetate（51110-01-1 Free base）	Somatostatin	GPCR/G Protein
	Somatostatin acetate 是一种内源性分泌的细胞增殖抑制剂，具有潜在的抗肿瘤活性，可用于研究癌症和神经系统疾病。
TP1035	Cyclic somatostatin SRIF-14,合成生长抑素,环状生长激素抑制素,Somatostatin-14	Others	Others
	Cyclic somatostatin (SRIF-14) 是生长激素释放抑制因子，可用于研究胃十二指肠溃疡出血。
T40680	[Tyr11]-Somatostatin [Tyr11]-Somatostatin
	[Tyr11]-Somatostatin is a neuroactive peptide utilized in proteomics research. It belongs to a class of neuroactive substances that play a role in modulating retinal physiology.
TP1302	Somatostatin
	Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and
T40679	[Tyr1]-Somatostatin-14 [Tyr1]-Somatostatin-14
	[Tyr1]-Somatostatin-14 could binds to SSTR2.
TP1810	Somatostatin-25
	Somatostatin is an endogenous neuropeptide hormone found in the brain and pancreas. Somatostatin binds several isoforms of the somatostatin receptor, exhibiting anxiolytic, antiepileptic/anticonvulsant, and anorexigenic activities.
T26200	Somatostatin RC 102 Somatostatin RC102,Somatostatin-RC-102,Somatostatin RC-102	Others	Others
	Somatostatin RC 102 is a peptide hormone. It regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.
TP2124	Somatostatin 1-28
	Somatostatin receptor agonist, derived from the post-translational cleavage of prosomatostatin.
T2584	Octreotide SMS 201-995,奥曲肽	Somatostatin	GPCR/G Protein
	Octreotide (SMS 201-995) 是一种有效的生长激素、胰高血糖素和胰岛素抑制剂。它主要与生长抑素 2、3 和 5 亚型受体结合，可增强 Gi 活性，降低胞内 cAMP 的产生。
TP1790	Tyr-Somatostatin-14
	Tyr-Somatostatin-14 is a modified peptide incorporating an additional Tyrosine (amino acid) into the structure of Somatostatin-14.
TP1258	Somatostatin-28 (1-12) 1-12-Somatostatin-28,Somatostatin-28 1-12
	Somatostatin-28 (1-12) is a somatostatin fragment which is monitored in brain tissue to track processing of somatostatin.
TP1823	Somatostatin-28 (1-14) Somatostatin-28 1-14
	Somatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28. Somatostatin 28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a large precursor, preprosomatostatin.
T34683	Somatostatin(3-6) Cys-lys-asn-phe	Others	Others
	Somatostatin(3-6) is a somatostatin fragment.
TP2207	Pasireotide Acetate	Somatostatin	GPCR/G Protein
	Pasireotide acetate 是长效的环己肽生长激素抑制素类似物，具有抗分泌、抗增殖和促凋亡活性。它可抑制 GH、IGF-I 和 ACTH 的分泌，可用于研究肢端肥大症和库欣病。它还可以提高生长抑素受体的激动剂活性，对sst1、2、3、4、5的pKi 分别为 8.2、9.0、9.1、小于7.0 和 9.9。
T9692	Paltusotine	Somatostatin	GPCR/G Protein
	Paltusotine 是一种口服有效的，非肽选择性生长抑素 2 型受体激动剂。在长效生长抑素受体配体作用后，Paltusotine 仍可维持 GH 和 IGF-1 水平。
T7829	FK962	Somatostatin	GPCR/G Protein
	FK962 是抑制生长抑素释放的增强剂，具有增强认知效果。
T76460	Tyr-Somatostatin-28
	Tyr-Somatostatin-28 是一种生长抑素，在 Somatostatin-28 的基础上添加了一个酪氨酸。
T4119	Octreotide Acetate 醋酸奥曲肽,SMS 201995,Longastatin,Sandostatin,SMS 201-995 (acetate)	Somatostatin	GPCR/G Protein
	Octreotide Acetate (Sandostatin) 是一种长期有效的合成生长抑素八肽类似物，可抑制生长激素的分泌。
T20204	Edotreotide 依多曲肽,SMT 487,SMT487,SMT-487	Others	Others
	Edotreotide (SMT-487) 是生长抑素类似物。它与多种放射性核素联合使用，拥有研究和诊断某些类型癌症的潜能。
T83494	[D-Trp8,Tyr11] Somatostatin
	[D-Trp8,Tyr11] Somatostatin是一种somatostatin的类似物，后者是一种调节多种身体机能的激素。在该化合物中，DTrp8残基的加入可以提高其稳定性。
T83493	[D-Trp8] Somatostatin-14
	[D-Trp8] Somatostatin-14为一种十四肽生长抑素类似物，其活性优于天然Somatostatin。
T76461	[Nle8] Somatostatin (1-28)
	[Nle8] Somatostatin (1-28)为生长抑素(1-28)的衍生物，其特征在于第8位的甲硫氨酸被正亮氨酸所替代。该化合物能够促使淀粉酶的释放，并增加胰腺腺泡中的环AMP水平。
T83546	(D-Trp8,D-Cys14)-Somatostatin-14
	"(D-Trp8,D-Cys14)-Somatostatin-14"为一种生长抑素合成类似物，主要用于代谢相关疾病研究。
T76459	[Tyr12] Somatostatin 28 (1-14)
	[Tyr12] Somatostatin 28 (1-14)，是Somatostatin-28 (1-14)的类似物，属于神经肽生长抑素-28的N-末端片段。
TP2045	CH 275
	Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin release in the rat nucleus accumbens
T76612	(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide
	(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide (Compound 4) 是一种生长抑素类似物，对 SSTR5、SSTR3、SSTR2、SSTR1和 SSTR4的Kd 分别为 0.61、11.05、23.5、1200 和 >1000 nM。
T80135	Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11)
	Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11)，一种生长抑素激动剂，用于癌症研究。
TP2052L	CTOP acetate	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	CTOP acetate 是一种生长抑素类似物和μ-阿片受体拮抗剂。
T28743	Seglitide acetate MK 678,MK678,MK-678	Somatostatin	GPCR/G Protein
	Seglitide acetate (MK-678) 是一种选择性的 sst2生长抑素受体激动剂。
TP1570L	Cortistatin-14 acetate Cortistatin-14 acetate(186901-48-4 Free base)	Somatostatin	GPCR/G Protein
	Cortistatin-14 acetate 是一种与生长抑素-14结构相似的神经肽，通过生长抑素受体 (sst1-sst5) 结合并发挥作用。Cortistatin-14 acetate 具有抗惊厥、神经保护作用和显著的抗炎作用。
T39262L	BIM-23190 aceate	Somatostatin	GPCR/G Protein
	BIM-23190 aceate 是一种生长抑素类似物，一种 SSTR2 和 SSTR5 的选择性激动剂。 BIM-23190 可用于癌症和肢端肥大症研究。
T8359	Lanreotide acetate Lanreotide acetate (108736-35-2 free base),BIM 23014 (acetate),BIM 23014 acetate	Others	Others
	Lanreotide acetate (BIM 23014 acetate) 是生长抑素类似物，具有抗肿瘤活性，可用于类癌综合症。
T21567L	Cyclosomatostatin Acetate Cyclosomatostatin Acetate （84211-54-1 Free base）	Somatostatin	GPCR/G Protein
	Cyclosomatostatin Acetate 是有效的生长抑素受体拮抗剂。Cyclosomatostatin Acetate 在直肠癌 (CRC) 细胞中可以抑制 SSTR1的信号传导，并降低结细胞增殖、ALDH+ 细胞群体大小和球形成。
TP1188L	Cortistatin 14, human, rat acetate	Somatostatin	GPCR/G Protein
	Cortistatin 14, human, rat acetate 是一种与 somatostatin-14 结构相似的神经肽，具有抗惊厥、神经保护作用和显着的抗炎特性。 Cortistatin 14, human, rat acetate 通过与生长抑素受体结合并发挥其功能。
TP1346	CYN 154806 TFA CYN 154806 TFA	Somatostatin	GPCR/G Protein
	CYN 154806 TFA(183658-72-2 free base) 是一种环状八肽，是一种有效的选择性生长抑素 sst2 受体拮抗剂。对于重组 sst2、sst1、sst3、sst4 和 sst5 受体，pIC50 值分别为 8.58、5.41、6.07、5.76 和 6.48。
T27787L	L-797,591 hydrochloride L-797,591 hydrochloride(217480-24-5 Free base)	Others	Others
	L-797,591 hydrochloride 对生长抑素受体亚型 1 (SSTR1)有活性。L-797,591 hydrochloride 常与 AG1478 联合使用来增强表达 SSTR1的细胞中 p-ERK5的表达。L-797,591 hydrochloride 在共转染的细胞中显著增强了 p38的磷酸化，这一作用在与 AG1478联合处理时被逆转。
TP2050L	CTAP(TFA） (103429-32-9 free base) CTAP(TFA）	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	CTAP(TFA) (103429-32-9 free base) 是一种有效的、高度选择性的、脑渗透性 μ-阿片受体拮抗剂，IC50 为 3.5 nM。它的选择性比 δ 阿片类药物 (IC50=4500 nM) 和生长抑素受体高 1200 倍以上。 CTAP TFA 可用于研究 L-DOPA 诱导的运动障碍 (LID)
T23073	NNC 26-9100	Others	Others
	Somatostatin sst4 receptor agonist
T23479	TT 232	Others	Others
	sst1/sst4 somatostatin receptors agonist
T30175	Ass 51 Ass-51,Ass51	Others	Others
	Ass 51 is a somatostatin analog.
T35142	Wy 40770 Wy40770,Wy-40770	Others	Others
	Wy 40770 is an analog of somatostatin.
T24860	TC-G1003 TC G1003	Others	Others
	TC-G1003 is an effective agonist of the somatostatin sst2 receptor.
T28220	NVP ACQ090 NVP-ACQ090,ACQ090,ACQ 090,NVPACQ090,ACQ-090	Others	Others
	NVP ACQ090 is a potent and subtype-selective somatostatin sst(3) receptor antagonist.
T27783	L-779976 L-779,976,L779,976,L779976,L 779976,L 779,976	Others	Others
	L-779,976 is an agonist of somatostatin receptor.
T40886	Onzigolide BIM-23A760,TBR-760,Onzigolide
	Onzigolide (BIM-23A760), a chimeric compound combining properties of both dopamine and somatostatin, exhibits strong agonistic activity towards the D2 subtype of dopamine receptors (D2R) as well as type 2 somatostatin receptors (SSTR2).
T69836	Paltusotine HCl	Others	Others
	Paltusotine, also known as CRN00808, is a somatostatin receptor agonist.
T34272	RC 121 RC121,IM 4-28,RC-121,P-Cttlvc-T	Others	Others
	RC 121 is a highly potent somatostatin (SRIF) analog.

化合物

Cyclic somatostatin Acetate

Cat.No: TP1035L

Synonym: Somatostatin (sheep), monoacetate (salt),Cyclic somatostatin Acetate(38916-34-6 free base),Somatostatin-14,SRIF-14,monoacetate (salt)

Target: Others

Tyr-Somatostatin-14 acetate

Cat.No: TP1790L

Synonym: Tyr-Somatostatin-14 acetate(58100-03-1 free base)

Target: Others

Somatostatin 1-28 acetate

Cat.No: TP2124L

Synonym: Somatostatin 1-28 acetate(74315-46-1 Free base)

Target: Somatostatin

Somatostatin acetate

Cat.No: TP1302L

Synonym: Somatostatin acetate（51110-01-1 Free base）

Target: Somatostatin

Cyclic somatostatin

Cat.No: TP1035

Synonym: SRIF-14,合成生长抑素,环状生长激素抑制素,Somatostatin-14

Target: Others

[Tyr11]-Somatostatin

Cat.No: T40680

Synonym: [Tyr11]-Somatostatin

Cat.No: TP1302

[Tyr1]-Somatostatin-14

Cat.No: T40679

Synonym: [Tyr1]-Somatostatin-14

Somatostatin-25

Cat.No: TP1810

Somatostatin RC 102

Cat.No: T26200

Synonym: Somatostatin RC102,Somatostatin-RC-102,Somatostatin RC-102

Target: Others

Somatostatin 1-28

Cat.No: TP2124

Cat.No: T2584

Synonym: SMS 201-995,奥曲肽

Target: Somatostatin

Tyr-Somatostatin-14

Cat.No: TP1790

Somatostatin-28 (1-12)

Cat.No: TP1258

Synonym: 1-12-Somatostatin-28,Somatostatin-28 1-12

Somatostatin-28 (1-14)

Cat.No: TP1823

Synonym: Somatostatin-28 1-14

Somatostatin(3-6)

Cat.No: T34683

Synonym: Cys-lys-asn-phe

Target: Others

Pasireotide Acetate

Cat.No: TP2207

Target: Somatostatin

Cat.No: T9692

Target: Somatostatin

Cat.No: T7829

Target: Somatostatin

Tyr-Somatostatin-28

Cat.No: T76460

Octreotide Acetate

Cat.No: T4119

Synonym: 醋酸奥曲肽,SMS 201995,Longastatin,Sandostatin,SMS 201-995 (acetate)

Target: Somatostatin

Cat.No: T20204

Synonym: 依多曲肽,SMT 487,SMT487,SMT-487

Target: Others

[D-Trp8,Tyr11] Somatostatin

Cat.No: T83494

[D-Trp8] Somatostatin-14

Cat.No: T83493

[Nle8] Somatostatin (1-28)

Cat.No: T76461

(D-Trp8,D-Cys14)-Somatostatin-14

Cat.No: T83546

[Tyr12] Somatostatin 28 (1-14)

Cat.No: T76459

Cat.No: TP2045

(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide

Cat.No: T76612

Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11)

Cat.No: T80135

Cat.No: TP2052L

Target: Opioid Receptor

Seglitide acetate

Cat.No: T28743

Synonym: MK 678,MK678,MK-678

Target: Somatostatin

Cortistatin-14 acetate

Cat.No: TP1570L

Synonym: Cortistatin-14 acetate(186901-48-4 Free base)

Target: Somatostatin

BIM-23190 aceate

Cat.No: T39262L

Target: Somatostatin

Lanreotide acetate

Cat.No: T8359

Synonym: Lanreotide acetate (108736-35-2 free base),BIM 23014 (acetate),BIM 23014 acetate

Target: Others

Cyclosomatostatin Acetate

Cat.No: T21567L

Synonym: Cyclosomatostatin Acetate （84211-54-1 Free base）

Target: Somatostatin

Cortistatin 14, human, rat acetate

Cat.No: TP1188L

Target: Somatostatin

Cat.No: TP1346

Synonym: CYN 154806 TFA

Target: Somatostatin

L-797,591 hydrochloride

Cat.No: T27787L

Synonym: L-797,591 hydrochloride(217480-24-5 Free base)

Target: Others

CTAP(TFA） (103429-32-9 free base)

Cat.No: TP2050L

Synonym: CTAP(TFA）

Target: Opioid Receptor

Cat.No: T23073

Target: Others

Cat.No: T23479

Target: Others

Cat.No: T30175

Synonym: Ass-51,Ass51

Target: Others

Cat.No: T35142

Synonym: Wy40770,Wy-40770

Target: Others

Cat.No: T24860

Synonym: TC G1003

Target: Others

Cat.No: T28220

Synonym: NVP-ACQ090,ACQ090,ACQ 090,NVPACQ090,ACQ-090

Target: Others

Cat.No: T27783

Synonym: L-779,976,L779,976,L779976,L 779976,L 779,976

Target: Others

Cat.No: T40886

Synonym: BIM-23A760,TBR-760,Onzigolide

Paltusotine HCl

Cat.No: T69836

Target: Others

Cat.No: T34272

Synonym: RC121,IM 4-28,RC-121,P-Cttlvc-T

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02910	Somatostatin Protein, Mouse, Recombinant (His & KSI) Sst,Somatostatin	Mouse	E. coli
	Somatostatin Protein, Mouse, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 18.5 kDa and the accession number is P60041.
TMPY-06364	SSTR2/SSTR2A Protein-VLP, Human, Recombinant somatostatin receptor 2	Human	HEK293 Cells
	SSTR2/SSTR2A Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 41.34 kDa and the accession number is P30874-1.
TMPY-06360	SSTR2/SSTR2B Protein-VLP, Human, Recombinant somatostatin receptor 2	Human	HEK293 Cells
	SSTR2/SSTR2B Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 40.01 kDa and the accession number is P30874-2.
TMPJ-01268	ERP27 Protein, Human, Recombinant (His) C12orf46,ER Protein 27,Endoplasmic Reticulum Resident Protei...	Human	HEK293 Cells
	Endoplasmic reticulum resident protein 27, also known as ER protein 27, C12orf46 and ERP27, is an endoplasmic reticulum luminal protein which is a member of the protein disulfide isomerase family. ERP27 contains one thioredoxin domain and does not contain a CXXC active site motif. ERP27 is widely expressed in many tissues; it has highest expression in pancreas, with lower levels in spleen, lung, kidney, thymus, and bone marrow. ERP27 interacts with PDIA3 and binds somatostatin-14 via hydrophobic...
TMPJ-00742	GCG Protein, Human, Recombinant (His) Glicentin,GRPP,GLP-2,Glucagon-Like Peptide 1,OXM,Glucagon,GL...	Human	HEK293 Cells
	Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin....
TMPY-01635	PCSK1 Protein, Human, Recombinant (His) proprotein convertase subtilisin/kexin type 1,SPC3,PC1,BMIQ1...	Human	HEK293 Cells
	Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the proteolytic cleavage of prohormones to their intermediate (or sometimes completely cleaved) forms. It is present only in neuroendocrine cells such as brain, pituitary and adrenal, and most often cleaves after a pair of basic residues within prohormones but can occasionally cleav...

重组蛋白

Somatostatin Protein, Mouse, Recombinant (His & KSI)

Cat.No: TMPH-02910

Species: Mouse

Expression System: E. coli

SSTR2/SSTR2A Protein-VLP, Human, Recombinant

Cat.No: TMPY-06364

Species: Human

Expression System: HEK293 Cells

SSTR2/SSTR2B Protein-VLP, Human, Recombinant

Cat.No: TMPY-06360

Species: Human

Expression System: HEK293 Cells

ERP27 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01268

Species: Human

Expression System: HEK293 Cells

GCG Protein, Human, Recombinant (His)

Cat.No: TMPJ-00742

Species: Human

Expression System: HEK293 Cells

PCSK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01635

Species: Human

Expression System: HEK293 Cells

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