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Cat. No. | Product Name | Form | Specificity Of Inhibition |
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C0050 |
BCA Protein Quantification Kit
BCA蛋白浓度测定试剂盒 |
Solution in bottle |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T80024 |
Cationic Bovine Serum Albumin
cBSA, chemically modified cationic bovine serum albumin |
Others | Others |
Cationic Bovine Serum Albumin(带正电荷的牛血清白蛋白)是由583个氨基酸组成的蛋白质,具有三个同源的全α结构域。该蛋白质与Tanshinone IIA联用,在缺血性脑卒中中展现出显著的神经保护作用。 | |||
T9290 |
3-hydroxy-phthalicanhydrid
|
Others | Others |
3-hydroxy-phthalicanhydrid 用于合成3-羟基邻苯二甲酸酐修饰的人血清白蛋白。 | |||
T18889 |
5-Aminofluorescein
5-氨基荧光素,5-AF |
Others | Others |
5-Aminofluorescein (5-AF) (5-AF) is a covalently-bound fluorescence marker conjugated with human serum albumin. It exhibits an excitation wavelength of 490 nm and an emission wavelength of 515 nm. | |||
T29689 |
AFB1-N7-guanine
|
Others | Others |
In epidemiological studies, Aflatoxin B1-N7-guanine serum albumin adducts have been established as biomarkers of dietary aflatoxin exposure. | |||
T29838 |
Albuminamide
Asp-thr-his-lys-ser-glu-ile-NH2 |
Others | Others |
Albuminamide is a novel peptide amide that has an identical sequence to the N-terminal (1-7) fragment of bovine serum albumin. | |||
T77146 | Regavirumab | ||
Regavirumab (MCA C23)为针对巨细胞病毒(CMV)、人血清白蛋白(HSA)及氨基乙酸的人源单克隆抗体。 | |||
T25287 |
Dansyllysine
Dns-lysine |
Others | Others |
Dansyllysine is utilized to study binding conformations of drugs to human serum albumin and is utilized as a template molecule to form molecularly imprinted monolayers (MIMs) useful to produce optical biosensor recognition elements. | |||
T68386 |
(R)-Duloxetine Hydrochloride
|
Others | Others |
(R)-Duloxetine Hydrochloride is a napthalenyloxy-substituted amine used in binding studies of human serum albumin along with (S)-Duloxetine. Unlike its enantiomer, it is not a very effective dual serotonin and norepinephrine reuptake inhibitor (SNRI). | |||
T82606 |
Dazodalibep
MEDI 4920,VIB 4920 |
||
Dazodalibep(MEDI 4920; VIB 4920)为针对CD40LG/TNFSF5的单克隆抗体,其结构中融合了ALB/HSA。 | |||
T35865 |
Telmisartan Acyl-β-D-Glucuronide
|
Others | Others |
Telmisartan acyl-β-D-glucuronide is a major metabolite of the angiotensin II receptor antagonist telmisartan . It does not bind human serum albumin and is cleared from rat plasma with a clearance rate of 180 ml/min/kg following intravenous administration. | |||
T36128 |
Tolmetin β-D-Glucuronide
|
Others | Others |
Tolmetin β-D-Glucuronide 与人血清白蛋白具有反应特性,可通过串联质谱法鉴定结合位点和反应机制。 | |||
T82924 |
Balugrastim
CG 10639 |
||
Balugrastim (CG 10639)为新型长效G-CSF,由重组人血清白蛋白与G-CSF遗传融合制成,适用于乳腺癌研究。 | |||
T77058 | Lerodalcibep | ||
Lerodalcibep (LIB003) 是一种重组融合蛋白,由PCSK9结合域 (adnectin) 与人血清白蛋白组成。作为降脂剂,Lerodalcibep 适用于高胆固醇血症和心血管疾病的研究。 | |||
T76885 | Sonelokimab | ||
Sonelokimab (ALX 0761; M 1095) 是三价纳米抗体,特异性结合人白介素(IL)-17A、IL-17F及人血清白蛋白VHH,由单价骆驼来源纳米抗体构成,展现于斑块型银屑病研究中的应用潜力。 | |||
T36398 |
Paclitaxel octadecanedioate
|
Others | Others |
Paclitaxel octadecanedioate is a prodrug form of paclitaxel that is comprised of paclitaxel conjugated to 1,18-octadecanedioic acid.1 Unlike paclitaxel, it does not promote tubulin polymerization in vitro when used at a concentration of 10 μM. A 5:1 mixture of paclitaxel octadecanedioate:human serum albumin (HSA) is cytotoxic to HT-1080, PANC-1, and HT-29 cells (IC50s = 12, 2.48, and 8.62 nM, respectively). This mixture reduces tumor growth and increases survival in an HT-1080 mouse xenograft mo... | |||
T77126 | Ozoralizumab | ||
Ozoralizumab (ATN-103) 为一种针对TNFα的人源化抗体。该化合物为一种三价人源化纳米抗体,由两个针对人TNFα的纳米抗体和一个针对人血清白蛋白(HSA)的纳米抗体构成,适用于关节炎研究。 | |||
T82600 |
DDAO-C6
|
||
DDAO-C6为酯环酮衍生物,高度特异性荧光探针,专用于检测人血清白蛋白(HSA)。同时,DDAO-C6作为酶激活的近红外荧光探针,适用于通过肠道微生物内源性脂肪酶的活性变化进行目测(Ex/Em=600/658 nm)。 | |||
T76878 | Vobarilizumab | ||
Vobarilizumab (ALX-0061) 是一种抗 IL-6R 单克隆抗体 (mAb) (Kd: 0.19 pM)。Vobarilizumab 由一个抗 IL-6R 结构域和一个抗人血清白蛋白结构域组成。Vobarilizumab 可用于炎症性自身免疫性疾病的研究,如类风湿性关节炎。 | |||
T79282 |
Antibacterial agent 144
|
Others | Others |
Antibacterialagent 144(compound 8e)是一款效能超过氯霉素和阿莫西林的抗菌药物,专门针对具有多重耐药性的金黄色葡萄球菌。该化合物通过破坏细菌的细胞质膜和抑制生物膜形成来发挥作用。Antibacterialagent 144能与HSA紧密结合(Kd=13.2 μM),显示出卓越的杀菌活性。它还能与DNA相结合,形成超分子复合物,有效阻断DNA复制过程。 | |||
T78445 |
Bromocresol green
|
||
Bromocresol green是一种pH敏感的三苯甲烷染料,专用于测定蛋白质及血清中的白蛋白浓度。此生物碱性染料在pH值3.0至7.5的范围内颜色从黄绿到蓝绿变化。在酸性条件下(例如pH=4.15),Bromocresol green显黄色(λmax=435 nm,质子化形式),而在碱性环境下则转为蓝色(λmax=615 nm,去质子化形式)。因此,它被广泛用作pH指示剂,在生化分析中有着重要应用。Bromocresol green还用于测定肌酐等分子浓度及评估细胞存活率。 | |||
T83922 |
Pep2 Peptide
|
||
Pep2 peptide是一种针对跨膜糖蛋白CD36的肽配体,CD36也被称为清道夫受体B2。在1 mM浓度使用时,Pep2 peptide在无细胞检测中选择性地与CD36结合,相比于人血清白蛋白(HSA)、IgG和CD44具有更高的亲和力。与不含Pep2 peptide的胶束相比,包裹抗癌剂多柔比星的Pep2 peptide功能化胶束能增加多柔比星在过表达CD36的HepG2肝细胞癌细胞中的细胞内输送,并提升细胞毒性。 | |||
T38075 |
ThioFluor 623
|
||
The rapid, selective, and sensitive sensing of thiols is important in diverse areas of research. This thiofluor 623 responds upon exposure to thiols with an increase in fluorescence intensity of up to 120-fold. The response is selective for thiols and occurs in aqueous media. In the absence of thiols, the probe is essentially non-fluorescent; thiols cause cleavage of the probe, generating a fluorophore with an absorption maximum of 563 nm and emission at 623 nm. The fluorescence quantum yield of... | |||
T83763 |
EPI-X4 TFA
Endogenous Peptide Inhibitor of CXCR4 |
||
EPI-X4是一种源于人血清白蛋白408-423氨基酸的内源性肽段,是趋化因子(C-X-C基序)受体4 (CXCR4)的拮抗剂。在0.8至1,000µM的浓度范围内,EPI-X4能抑制表达CXCR4的HEK293细胞中由趋化因子(C-X-C基序)配体12 (CXCL12)诱发的钙离子动员和受体内化。EPI-X4还能抑制CXCL12诱导的Jurkat T细胞和人类CD34+造血干细胞的迁移。体内实验中,EPI-X4(16µmol/kg)在急性过敏性气道高嗜酸性粒细胞疾病的小鼠模型中减少了Cxcr4依赖的炎症细胞气道浸润。慢性肾脏病患者尿液中EPI-X4的水平增高,并与肾小球滤过率(GFR)成反比。 | |||
T38002 |
LEO 39652
|
Others | Others |
LEO 39652 is a dual-soft PDE4 inhibitor with IC50s of 1.2 nM, 1.2 nM, 3.0 nM and 3.8 nM for PDE4A, PDE4B, PDE4C and PDE4D, respectively. LEO 39652 also inhibits TNF-α with an IC50 value of 6.0 nM. LEO 39652 is used for topical research of Atopic dermatitis (AD) [1]. LEO 39652 shows unbound in vitro potency when measured as LPS induced TNF-α release in human peripheral blood mononuclear cells (PBMC), incubated in serum free medium. LEO 39652 shows a relatively high binding to human serum albumin... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5664 |
Bovine Serum Albumin
牛血清白蛋白,BSA,Bovine albumin,Albumin bovine serum,白蛋白 |
Others | Others |
Bovine Serum Albumin (BSA) 是一种由三个同源全 α 结构域组成的 583 个氨基酸的蛋白质,是一种球状蛋白,可用于多种生物化学实验中。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00347 |
Serum Albumin Protein, Human, Recombinant (His & Avi)
Serum albumin,PRO0903,Albumin,PRO... |
Human | HEK293 Cells |
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. Serum Albumin Protein, Human, Recombinant (His & Avi) is... | |||
TMPK-00580 |
Serum Albumin Protein, Cynomolgus, Recombinant (His)
PRO1341,Albumin,PRO0883,FDAH,PRO0903,ALB,ANALBA, |
Cynomolgus | HEK293 Cells |
Serum Albumin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 67.1 kDa and the accession number is A2V9Z4-1. | |||
TMPK-00787 |
Serum Albumin Protein, Mouse, Recombinant (His)
Albumin,PRO0883,PRO0903,ANALBA,Serum a... |
Mouse | HEK293 Cells |
Serum Albumin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.19 kDa and the accession number is P07724. | |||
TMPK-00348 |
Serum Albumin Protein, Human, Recombinant (His & Avi), Biotinylated
ALB,PRO0883,PRO0903,FDAH,ANALBA,PRO1341,Serum a... |
Human | HEK293 Cells |
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. Serum Albumin Protein, Human, Recombinant (His & Avi), B... | |||
TMPH-00500 |
Serum albumin Protein, Canine, Recombinant (His)
Albumin,ALB |
Canine | P. pastoris (Yeast) |
Serum albumin Protein, Canine, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 67.7 kDa and the accession number is P49822. | |||
TMPH-00301 |
Serum albumin Protein, Bovine, Recombinant (His & Myc)
ALB,Albumin,BSA |
Bovine | P. pastoris (Yeast) |
Serum albumin Protein, Bovine, Recombinant (His & Myc) is expressed in yeast with C-6xHis-Myc tag. The predicted molecular weight is 70.1 kDa and the accession number is P02769. | |||
TMPY-00105 |
Recombinant Protein G
|
E. coli | |
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig... | |||
TMPJ-00758 |
AFP Protein, Mouse, Recombinant (His)
Alpha-fetoprotein,α-fetoglobulin,Alpha-1-fetoprotein,Afp,α-1... |
Mouse | HEK293 Cells |
Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitaminD (Gc) protein, and alpha-albumin. AFP is a major plasma protein produced by the yolk sac and the liver during fetal development. It is thought to be the fetal form of serum albumin. AFP binds to copper, nickel, fatty acids and bilirubin and is found in monomeric, dimeric and trimeric forms. AFP is one of the several embryo-specific proteins and is adominant serum protein as ea... | |||
TMPH-03516 |
NPTase Protein, S. aureus, Recombinant (His & SUMO)
30 kDa neutral phosphatase |
Staphylococcus aureus | E. coli |
Highly cationic enzyme that can bind human or rat immunoglobulins as well as serum albumin, and could therefore be involved in post-infectious sequelae. NPTase Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.7 kDa and the accession number is P21222. | |||
TMPH-03155 |
Lys-gingipain HG66 Protein, Porphyromonas gingivalis, Recombinant (His & Myc)
Lys-gingipain HG66,kgp |
Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. Lys-gingipain HG66 Protein, Porphyromonas gingivalis, Recombinant (His & Myc) is expressed in E.... | |||
TMPH-03154 |
Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His)
kgp,Lys-gingipain 381 |
Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His) is expressed in E. coli e... | |||
TMPH-03156 |
Lys-gingipain Protein, Porphyromonas gingivalis, Recombinant (His & SUMO)
Lysine-specific cysteine proteinase Kgp,Lys-gingipain,kgp |
Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. Lys-gingipain Protein, Porphyromonas gingivalis, Recombinant (His & SUMO) is expressed in E. col... | |||
TMPJ-00833 |
MPO Protein, Mouse, Recombinant (His)
MPO,Myeloperoxidase |
Mouse | HEK293 Cells |
Myeloperoxidase (MPO) is a hemecontaining enzyme belonging to the XPO subfamily of peroxidases. It is an abundant neutrophil and monocyte glycoprotein that catalyzes the hydrogen peroxidedependent conversion of chloride, bromide, and iodide to multiple reactive species. MPO activity results in protein nitrosylation and the formation of 3-chlorotyrosine and dityrosine crosslinks. Modification of ApoB100, as well as the lipid and cholesterol components of LDL and HDL, promotes the development of a... |