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Search Results for " selenocysteine "

Targets Recommended: Others

5

抑制剂 & 化合物

1

天然产物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9427	Selenocysteine	Others	Others
	Selenocysteine 被认为是核糖体介导的蛋白质合成中的第 21 个氨基酸，其特异性掺入由 UGA 密码子指导。
T8375	ML-210 CID 49766530	Ferroptosis; GPX; Glutathione Peroxidase; Ras	Apoptosis; GPCR/G Protein; MAPK; Metabolism; oxidation-reduction
	ML-210 (CID 49766530) 是一种共价的选择性谷胱甘肽过氧化物酶 4 (GPX4) 抑制剂，EC50为 30 nM。它与 GPX4 硒代半胱氨酸残基结合，具有抗癌活性。
T78587	Se-Methylselenocysteine hydrochloride Methylselenocysteine hydrochloride,Se-Methylseleno-L-cysteine hydrochloride	Beta-Secretase	Neuroscience
	Se-Methylselenocysteine hydrochloride 是一种甲基硒的前体，展现出显著的癌症化学预防和抗氧化活性。该化合物拥有优良的口服生物活性，并能有效诱导细胞凋亡(apoptosis)。
T34604	Selenodicysteine	Others	Others
	Selenodicysteine is the 21st proteinogenic amino acid. Selenocysteine exists naturally in all three domains of life, but not in every lineage.
T39048	Sel-green
	Sel-green is a selective selenol fluorescent probe used for quantifying the selenocysteine (Sec) content in the selenoenzyme thioredoxin reductase, as well as imaging endogenous Sec in live HepG2 cells.

化合物

Selenocysteine

Cat.No: T9427

Target: Others

Cat.No: T8375

Synonym: CID 49766530

Target: Ferroptosis, GPX, Glutathione Peroxidase, Ras

Se-Methylselenocysteine hydrochloride

Cat.No: T78587

Synonym: Methylselenocysteine hydrochloride,Se-Methylseleno-L-cysteine hydrochloride

Target: Beta-Secretase

Selenodicysteine

Cat.No: T34604

Target: Others

Cat.No: T39048

Cat. No.	Product Name	Target	Signaling Pathways
T7727	Se-Methylselenocysteine Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC	BCL; IAP; Caspase	Apoptosis; Proteases/Proteasome
	Se-Methylselenocysteine (Se-MSC) 是具有口服活性的甲基硒前体，具有强大的抗氧化活性和抗癌活性。Se-Methylselenocysteine 可诱导细胞凋亡。

天然产物

Se-Methylselenocysteine

Cat.No: T7727

Synonym: Se MSC,SeMCys,MSeC,L-硒甲基硒代半胱氨酸,Se-MSC,SeMSC

Target: BCL, IAP, Caspase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03754	SCLY Protein, Human, Recombinant (His) selenocysteine lyase,hSCL,SCL	Human	Baculovirus Insect Cells
	SCLY, also known as selenocysteine lyase, belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. It is a novel enzyme that exclusively decomposes L-selenocysteine into L-alanine and H2Se in various mammalian tissues. SCLY contains pyridoxal 5'-phosphate and weighs approximately 85,000. SCLY participates in selenoamino acid metabolism. It employs one cofactor, pyridoxal phosphate. Its maximum reactivity is at about pH 9.0. It was shown that 1 mol of selenocysteine is conver...
TMPH-01813	SEPSECS Protein, Human, Recombinant (E. coli, His) Selenocysteine synthase,O-phosphoseryl-tRNA(Sec) se...	Human	E. coli
	Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. SEPSECS Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 53.4 kDa and the accession number is Q9HD40.
TMPH-01812	SEPSECS Protein, Human, Recombinant (His) SLA-p35,SEPSECS,Sep-tRNA:Sec-tRNA synthase,Selenocystein...	Human	P. pastoris (Yeast)
	Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. SEPSECS Protein, Human, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 56.5 kDa and the accession number is Q9HD40.
TMPJ-01311	EPT1 Protein, Human, Recombinant (GST) hEPT1,Selenoprotein I,SELI,EPT1,Ethanolaminephosphotransfera...	Human	E. coli
	Ethanolaminephosphotransferase 1 (EPT1) is an enzyme that belongs to the CDP-Alcohol Phosphatidyltransferase Class-I Family. EPT1 is a Selenoprotein, which contains a Selenocysteine (Sec) residue at its active site. The Selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of Selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop sig...
TMPY-02768	Selenoprotein M Protein, Human, Recombinant (His) SEPM	Human	E. coli
	Selenoprotein M is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine M is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures....
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His) thioredoxin reductase 1,TR1,TXNR,TR,TRXR1,GRIM-12	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th...
TMPJ-00988	SEPHS1 Protein, Human, Recombinant (His) water dikinase 1,SELD,Selenophosphate synthase 1,SEPHS1,SPS1...	Human	HEK293 Cells
	Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. It has four different isoforms by alternative splicing. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased, which Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. SEPHS1 can be activated by phosphate ions and by potassium ions. It can synthesize synthesizes selenophosphate from selenide and ATP....

重组蛋白

SCLY Protein, Human, Recombinant (His)

Cat.No: TMPY-03754

Species: Human

Expression System: Baculovirus Insect Cells

SEPSECS Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01813

Species: Human

Expression System: E. coli

SEPSECS Protein, Human, Recombinant (His)

Cat.No: TMPH-01812

Species: Human

Expression System: P. pastoris (Yeast)

EPT1 Protein, Human, Recombinant (GST)

Cat.No: TMPJ-01311

Species: Human

Expression System: E. coli

Selenoprotein M Protein, Human, Recombinant (His)

Cat.No: TMPY-02768

Species: Human

Expression System: E. coli

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

Cat.No: TMPY-02271

Species: Human

Expression System: E. coli

SEPHS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00988

Species: Human

Expression System: HEK293 Cells

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