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Search Results for " schistosoma "

Targets Recommended: Androgen Receptor

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T0272	Nilutamide 尼鲁米特,RU23908	Androgen Receptor	Endocrinology/Hormones
	Nilutamide (RU23908) 是一种非甾体抗雄激素药物，有用于转移性前列腺癌的潜力。
T12770	RR-11a analog aza-peptide Michael acceptor, 7a	Parasite	Microbiology/Virology
	RR-11a analog (aza-peptide Michael acceptor, 7a) 是一种天冬酰胺酰内肽酶抑制剂，对阴道毛滴虫中的 AE1、蓖麻硬蜱中的 AE 和曼氏血吸虫中的 AE 的 IC50 分别为 4.5 nM、4.5 nM 和 31 nM。
T34809	Teroxalene hydrochloride Teroxalene HCl,NSC 138704	Others	Others
	Teroxalene Hydrochloride is disubstituted piperazine used to treat animals with Schistosoma mansoni.
T69421	Hydrolapachol	Others	Others
	Hydrolapachol is a novel potent and selective inhibitor of schistosoma mansoni dihydroorotate dehydrogenase (smdhodh)
T61549	HDAC8-IN-2	Others	Others
	HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 μM and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and greatly reduces egg laying in adult worm pairs [1].
T33957	PF-Alkyne PF Alkyne
	PF-Alkyne is a fluorophosphonate-based probe which specifically and covalently reacts with the tyrosine-111 residue of the Schistosoma japonicum GST (sjGST) tag. PF-Alkyne rapidly and site-selectively immobilizes sjGST fusion proteins.
T61538	Antiparasitic agent-10	Others	Others
	Antiparasitic agent-10 (Compound 94) is a potent anti-parasitic agent specifically designed to target and combat parasitic infections. It demonstrates notable anti-schistosomal activity, particularly against adults of Schistosoma mansoni. As a result, this compound holds significant potential for utilization in Schistosomiasis research as a viable treatment option [1].
T78391	DAUDA
	DAUDA (11-(dansylamino) undecanoic acid)是一种荧光脂肪酸类似物，对环境变化敏感。该分子通过调整其发射强度和荧光光谱与结合蛋白发生相互作用。在研究中，DAUDA用于评估天然脂肪酸与曼氏血吸虫Sm14脂肪酸结合蛋白多晶型的相对亲和力。
T78619	Z-Pro-Pro-CHO	Prolyl Endopeptidase (PREP)	Metabolism; Proteases/Proteasome
	Z-Pro-Pro-CHO为一种有效的脯氨酰寡肽酶抑制剂，其具有针对人类及曼氏血吸虫脯氨酰寡肽酶的较低半抑制浓度（IC50），分别为0.16 μM和0.01 μM。

化合物

Nilutamide

Cat.No: T0272

Synonym: 尼鲁米特,RU23908

Target: Androgen Receptor

RR-11a analog

Cat.No: T12770

Synonym: aza-peptide Michael acceptor, 7a

Target: Parasite

Teroxalene hydrochloride

Cat.No: T34809

Synonym: Teroxalene HCl,NSC 138704

Synonym: PF Alkyne

Target:

Antiparasitic agent-10

Target: Prolyl Endopeptidase (PREP)

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02157	GST Protein, Schistosoma japonicum, Recombinant	Schistosoma japonicum	Baculovirus Insect Cells
	Genetic engineers have used glutathione S-transferase to create the GST gene fusion system. This system is used to purify and detect proteins of interest. In a GST gene fusion system, the GST sequence is incorporated into an expression vector alongside the gene sequence encoding the protein of interest. Induction of protein expression from the vector's promoter results in expression of a fusion protein: the protein of interest fused to the GST protein. This GST-fusion protein can then be purifie...
TMPH-03763	Major egg antigen Protein, Schistosoma mansoni, Recombinant (His) p40,Major egg antigen	Schistosoma mansoni	E. coli
	Major egg antigen Protein, Schistosoma mansoni, Recombinant (His) is expressed in E. coli with N-terminal 6xHis tag. The predicted molecular weight is 43.4 kDa. Accession number: P12812

重组蛋白

GST Protein, Schistosoma japonicum, Recombinant

Cat.No: TMPY-02157

Species: Schistosoma japonicum

Expression System: Baculovirus Insect Cells

Major egg antigen Protein, Schistosoma mansoni, Recombinant (His)

Cat.No: TMPH-03763

Species: Schistosoma mansoni

Expression System: E. coli

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