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Search Results for " sch b "

Targets Recommended: Others

抑制剂 & 化合物

天然产物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T28708	Sch 24937	Others	Others
	Sch 24937 is a potent immunosuppressant on B lymphocyte mediated immune responses.
T12867L	SCH 50911	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	SCH 50911 is (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid and is a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor (IC50: 1.1 μM). SCH 50911 antagonizes GABA(B) autoreceptors, increasi
T12867	SCH 50911 hydrochloride	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	SCH 50911 hydrochloride is a selective, orally-active and competitive antagonist of γ-Aminobutyric acid B GABA(B) receptor(IC50 : 1.1 μM).
T16862	SCH-1473759	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	SCH-1473759 is an inhibitor of the aurora (IC50s: 4 and 13 nM for Aurora A and B, respectively).
T12864	SCH-1473759 hydrochloride	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	SCH-1473759 hydrochloride 是一种多靶点极光激酶抑制剂，对极光激酶 A 和 B 的 IC50值分别为 4 和13 nM。

化合物

Target: GABA Receptor

SCH 50911 hydrochloride

Cat.No: T12867

Synonym:

Target: GABA Receptor

SCH-1473759

Cat.No: T16862

Synonym:

Target: Aurora Kinase

SCH-1473759 hydrochloride

Cat.No: T12864

Synonym:

Target: Aurora Kinase

Cat. No.	Product Name	Target	Signaling Pathways
T2925	Schisandrin B gamma-Schisandrin,Schizandrin B,五味子素B,五味子乙素,Schisandrin B (Sch B),Wuweizisu-B	ATM/ATR; Reactive Oxygen Species; Autophagy	Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Schisandrin B (Schisandrin B (Sch B)) 是从五味子中分离联苯环辛二烯衍生物，对啮齿类动物的肝脏和心脏的抗氧化作用。

天然产物

Schisandrin B

Cat.No: T2925

Synonym: gamma-Schisandrin,Schizandrin B,五味子素B,五味子乙素,Schisandrin B (Sch B),Wuweizisu-B

Target: ATM/ATR, Reactive Oxygen Species, Autophagy

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01413	H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi) H-2K,OVA,MHC,H2-K1	Mouse	HEK293 Cells
	Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se...
TMPK-01412	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) SARS-CoV-2 epitope,MHC	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPK-01416	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,SARS-CoV-2 epitope	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.