38
23
1
8
10
Cat. No. | Product Name | ||
---|---|---|---|
L2510 | 脂代谢化合物库 | 492 compounds | |
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21240 |
Sodium caprate
Caprinic acid sodium salt,Sodium caprinate,癸酸钠,Decanoic acid, sodium salt,Sodium decanoate,Capric acid, sodium salt,Sodium decanoic acid |
Others | Others |
Sodium caprate (Sodium decanoate) 是己酸的钠盐,己酸是一种 10 个碳的饱和脂肪酸。它具有两亲性,可在水溶液中形成液晶相和胶束。 | |||
T4309 |
CIL56
CA3 |
Ferroptosis; ROS | Apoptosis; Immunology/Inflammation |
CIL56 (CA3) 是一种选择性铁死亡诱导剂,可通过产生铁依赖性活性氧来诱导细胞铁死亡。 | |||
T14878 |
CAY10566
|
Dehydrogenase; Stearoyl-CoA Desaturase (SCD) | Metabolism |
CAY10566 是选择性的、口服具有活性的硬脂酰辅酶 A 去饱和酶 1 抑制剂,在小鼠和人酶测定中IC50分别为 4.5 和 26 nM。它具有显著的细胞活性,可阻断 HepG2 细胞中饱和长链脂肪酸-CoAs (LCFA-CoAs) 向单不饱和 LCFA-CoAs 的转化 。 | |||
T85254 |
1,2-Dinonadecanoyl-sn-glycero-3-PC
1,2-DNPC,PC (19:0/19:0),1,2-Dinonadecanoyl-sn-glycero-3-phosphocholine |
Others | Others |
1,2-Dinonadecanoyl-sn-glycero-3-PC (DNPC), a saturated phospholipid, serves as a standard in quantifying phosphatidylcholines in human synovial fluid and has been utilized in researching lipid bilayer phase transition dynamics. | |||
T85109 |
Didocosanoin
Dibehenin |
Others | Others |
Didocosanoin, a diacylglycerol, incorporates the saturated 22-carbon fatty acid, docosanoic acid, at both of its positions. | |||
T85133 |
Photoclick Myristic Acid
Click Tag™ Myristic Acid,YnMyr Diazirine X10,YnMyristic Diazirine X10 |
Others | Others |
Photoclick myristic acid, a saturated fatty acid derivative, features a terminal clickable alkyne moiety and a photoactivatable diazirine group at the 10th carbon position. This compound facilitates the study of protein lipidation through its application as a probe in long-chain saturated fatty acids. | |||
T19927 |
Asphalt
Bitumen,Asphalt fumes,Dacholeum |
Others | Others |
Asphalt is a dark liquid. It is also a mixture of heavy hydrocarbon residues including saturated and unsaturated hydrocarbons and aromatic hydrocarbons. | |||
T85104 |
Dinonadecanoin
|
Others | Others |
Dinonadecanoin is a diacylglycerol characterized by the presence of the saturated fatty acid, nonadecanoic acid (nonadecanoic acid), at two positions. | |||
T84507 |
Phytomonic Acid
Lactobacillic Acid |
Others | Others |
Phytomonic acid, a saturated fatty acid with a cyclopropane ring structure that behaves similarly to a double bond, predominates in gram-negative bacteria L. arabinosus, protozoa, and the seed oil of B. coccineus (Connaraceae). This compound may play a role in regulating cell membrane fluidity. | |||
T37682 |
3-hydroxy Tridecanoic Acid
|
Others | Others |
3-hydroxy Tridecanoic acid is a 13-carbon saturated fatty acid found in bacterial lipopolysaccharides (LPS). It can be used as an internal standard to detect markers of microorganisms in complex samples, including 3-hydroxy fatty acids found in LPS-containing bacteria and muramic acid found in bacterial cell wall peptidoglycan. | |||
T37677 |
3-hydroxy Docosanoic Acid
|
Others | Others |
3-hydroxy Docosanoic acid is a hydroxylated form of the 22-carbon saturated docosanoic acid . It is found in lipopolysaccharides from C. trachomatis and C. psittaci and in S. synnaedendra. 3-hydroxy Docosanoic acid, in the form of an acyl-CoA metabolite, is an intermediate in fatty acid chain elongation from arachidic acid to docosanoic acid (C22:0). | |||
T29275 |
1,3-Didecanoylglycerol
1,3-Dicaprin |
Others | Others |
1,3-Didecanoylglycerol is a saturated diacylglycerol with decanoic acid (Item No. 20838) at the sn-1 and sn-3 positions. It has been used in the formation of lipid monolayers in the study of lipases. | |||
T85019 |
1,2-O-Dihexadecyl-sn-glycerol
DG(O-16:0/O-16:0/0:0) |
Others | Others |
1,2-O-Dihexadecyl-sn-glycerol, a saturated dialkyl glyceryl ether featuring hexadecyl groups at the sn-1 and sn-2 positions, resembles the structure of diacylglycerol. This compound serves as a lipid anchor for synthesizing lactose-containing synthetic glycolipids. | |||
T35417 |
α-Linolenic Acid (sodium salt)
|
Others | Others |
α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation. | |||
T84543 |
Arachidoyl Ethanolamide
N-Arachidoylethanolamine |
Others | Others |
Arachidoyl ethanolamide, a saturated fatty acyl ethanolamide lacking classical (CB1/CB2) activity, plays a role in a complex system comprising central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology. This system has paved the way for extensive research in diverse fields such as memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation. Unlike other compounds, Arachidoyl ethanolamide does not bind to the murine ... | |||
T84441 |
1,2-O-Dioctadecyl-rac-glycerol
|
Others | Others |
1,2-O-Dioctadecyl-rac-glycerol, a saturated dialkyl glyceryl ether featuring octadecyl groups at the sn-1 and sn-2 positions, closely resembles the structure of diacylglycerol. This similarity allows its use in model lipid bilayers to explore the dynamics of different biological membrane compositions. | |||
T74315 |
16:0 EPC chloride
|
Others | Others |
16:0 EPC chloride,一种P-O-乙基衍生的饱和阳离子脂质,可用作DNA与RNA转染剂,亦作为疫苗制备及促进药物递送的辅助佐剂。 | |||
T84376 |
1-Palmitoyl-2-Oleoyl-sn-glycero-3-PA
1-Palmitoyl-2-Oleoyl-sn-glycero-3-Phosphatidic Acid,16:0-18:1 PA,1-Hexadecanoyl-2-Octadecanoyl-sn-glycero-3-phosphatidic Acid,1-Hexadecanoyl-2-Octadecenoyl-sn-glycero-3-phosphate,1-Palmitoyl-2-Oleoyl-sn-glycero-3-phosphate,16:0/18:1-PA,1-Hexadecanoyl-2-Octadecenoyl-sn-glycero-3-PA,PA(16:0/18:1),1,2-POPA |
Others | Others |
1-Palmitoyl-2-oleoyl-sn-glycero-3-PA (1,2-POPA) is a phospholipid featuring a palmitic acid (16:0) chain that is saturated and an oleic acid (18:1) chain that is monounsaturated, positioned at the sn-1 and sn-2 locations, respectively. This compound is utilized in creating micelles, liposomes, and various artificial membrane forms. | |||
T84449 |
1,3-Dipalmitoyl glycero-2-PE
1,3-DPPE |
Others | Others |
1,3-Dipalmitoyl glycero-2-phosphatidylethanolamine is a phospholipid incorporating saturated long-chain (16:0) stearic acid at the sn-1 and sn-3 positions, with phosphatidylethanolamine (PE) at the sn-2 position. Phosphatidylethanolamines, critical components of biological membranes, play essential structural and functional roles. Various PE types are instrumental in forming micelles, liposomes, and other synthetic membranes. | |||
T84520 |
Palmitic acid calcium
Calcium palmitate |
Others | Others |
Palmitic acid calcium,一种长链饱和脂肪酸,广泛存在于动物和植物中。它能在小鼠颗粒细胞诱导葡萄糖调节蛋白78 (GRP78) 和CCAAT/增强子结合蛋白同源蛋白 (CHOP) 的表达,可用于建立细胞脂肪变性模型。 | |||
T31292 |
Decalin
bicyclo[4.4.0]decane,decahydronaphthalene |
Others | Others |
Decalin (decahydronaphthalene, also known as bicyclo[4.4.0]decane), a bicyclic organic compound, is an industrial solvent. A colorless liquid with an aromatic odor, it is used as a solvent for many resins or fuel additives. It is the saturated analog of n | |||
T37678 |
3-hydroxy Lignoceric Acid
|
Others | Others |
3-hydroxy Lignoceric acid is a hydroxylated form of the 24-carbon saturated lignoceric acid . 3-hydroxy Lignoceric acid is found in minor amounts in Methyloligella, a novel Gram-negative bacteria. 3-hydroxy Lignoceric acid, in the form of an acyl-CoA metabolite, is an intermediate in fatty acid chain elongation from docosanoic acid to lignoceric acid (C24:0). | |||
T84438 |
6-Azidohexanoic Acid
Click Tag™ 6-Azidohexanoic Acid |
Others | Others |
6-Azidohexanoic acid, a six-carbon saturated fatty acid featuring an ω-terminal azide group, serves as a versatile linker for bioconjugation via copper(I)-catalyzed cycloaddition reactions (click chemistry). This functionality enables its initial acylation to a compound, forming a derivative that can subsequently be conjugated to another compound through click chemistry, facilitating the synthesis of complex molecules. | |||
T85211 |
Dieicosanoin
Glycerol diarachidate |
Others | Others |
Dieicosanoin是含有Arachidic acid的二酰基甘油,后者为一种20个碳主链的饱和长链脂肪酸,可从花生酱及厌氧真菌中提取。 | |||
T77788 |
Palmitic acid sodium
Sodium palmitate,Palmitic acid sodium |
||
Palmitic acid sodium(Sodium palmitate) 是饱和脂肪酸的一种,其在脂肪酸合成中形成。Palmitic acid sodium 能促进多种细胞系脂肪生成及细胞脂肪变性。 | |||
T85097 |
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE
16:0 Lyso-PE-d9,16:0 LPE-d9,1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-Phosphoethanolamine,1-Hexadecanoyl-d9-sn-glycero-3-Phosphoethanolamine |
Others | Others |
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE serves as an internal standard for quantifying 1-palmitoyl-2-hydroxy-sn-glycero-3-PE, a lysophospholipid naturally found to inhibit L. donovani promastigotes growth (GI50= 8 µM). Its levels are reduced in mice after alcohol-induced liver damage, in hepatocellular carcinoma mouse xenografts, and in humans following a rigorous three-day exercise regimen of 2.5 hours running daily and 14 hours post-regimen. This compound is also applied in measuring saturate... | |||
T77283 |
DSPE-Mal
|
Others | Others |
DSPE-MAL是具有硫醇活性的磷脂化合物,拥有两个饱和脂肪酸,能够在水中自组装成脂质双层结构。该化合物常用于构建脂质体,作为活性分子的纳米载体。 | |||
T37837 |
2-Methylhexacosane
|
Others | Others |
2-Methylhexacosane is a saturated hydrocarbon and an insect pheromone.1,2It has been found in the cuticle ofM. dasystomusfemales, but not males, where it contributes to the mating behavior of males, as well as inD. melanogasterfemales where it modulates aggression of males towards females. 2-methylhexacosane has also been found in yellow jacket (V. vulgaris) trail extracts.3 1.Spikes, A.E., Pashen, M.A., Millar, J.G., et al.First contact pheromone identified for a longhorned beetle (Coleoptera: ... | |||
T37123 |
1,2-Dioctanoyl PC
|
Others | Others |
Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Dioctanoyl PC is a synthetic analog of natural phosphatidylcholine species containing saturated C8:O fatty acids in the sn-1 and sn-2 positions of the glycerol backbone. It exhibits a critical micelle concentration (CMC) value of 0.25 mM at 27°C. 1,2-Dioctanoyl PC serves as an efficient substrate for phospholipase D (PLD) as well as sPLA2 isozymes from bovine pancreas and bee venom... | |||
T36731 |
Cholesteryl Heptadecanoate
|
Others | Others |
Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations. As such, it is commonly used as an internal standard for the quantification of cholesterol esters by GC- or LC-mass spectrometry. CEs are major constituents of lipoprotein particles carried in blood and accumulate in the fatty acid lesions of atherosclerotic plaques.... | |||
T35482 |
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE,1-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine |
Others | Others |
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid. [1] It inhibits the growth of L. donovani promastigotes (GIC50 = 8 uM). [2]1-Palmitoyl-2-hydroxy-sn-glycero-3-PE serum levels are decreased in a mouse model of alcohol-induced liver injury and in a hepatocellular carcinoma mouse xenograft model. [3] Human serum levels are also decreased immediately and 14 hours following an exercise regimen of 2.5 hours of running for three days. [1]1-Palmitoyl-2-hydroxy-sn-glycero-... | |||
T69350 |
Ethionamide HCl
|
Others | Others |
Ethionamide HCl is the salt form of Ethionamide, a second-line antitubercular agent that inhibits mycolic acid synthesis. Ethionamide is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and ... | |||
T73918 |
Lauroyl coenzyme A lithium
|
Others | Others |
Lauroyl coenzyme A lithium salt 是一种辅酶 A。辅酶 A 作为酰基载体,即乙酰辅酶 A。十二烷酰辅酶 A (C12-CoA) 是一种长链 (C-12) 饱和脂肪酰辅酶 A,用作脂质代谢的中间体,参与脂质生物合成和脂肪酸转运。月桂酰辅酶 A 是底物用于 FAM34A 蛋白和萤火虫荧光素酶的产物。 | |||
T35904 |
O-11
|
Others | Others |
O-11 is an analog of the fully saturated, 14-carbon fatty acid myristic acid, in which the methylene group at position 11 is replaced with oxygen. It is highly effective and selective at killingTrypanosoma brucei, the protozoan parasite responsible for African sleeping sickness, exhibiting an LD50of less than 1 μM in a cell culture assay.1,2The toxic effects of O-11 appear to be caused by its ability to inhibit the incorporation of a single myristate into the GPI anchor of the variant surface gl... | |||
T77228 |
Polyoxyethylene Sorbitan Monostearate
|
Others | Others |
Polyoxyethylene Sorbitan Monostearate 是一种由饱和脂肪酸硬脂酸 (C18:0) 构成的酯,广泛应用作药用辅料,包括表面活性剂、乳化剂、增溶剂和润湿剂。作为药用助剂,其主要作用是改善药物制剂的稳定性、溶解性和加工性,同时对药物的吸收、分布、代谢和消除 (ADME) 过程具有影响。 | |||
T85207 |
1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol
1,2-Palmitin-3-caprylin |
Others | Others |
1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol 是一种三酰基甘油,其结构特征在于 sn-1 和 sn-2 位置上连接有棕榈酸,在 sn-3 位置上连接有辛酸。棕榈酸,一种广泛存在于动植物体中的长链饱和脂肪酸,已知能够在小鼠颗粒细胞中诱导葡萄糖调节蛋白 78 (GRP78) 与 CCAAT/增强子结合蛋白同源蛋白 (CHOP) 的表达。辛酸,作为一种具有微弱腐臭味的油性液体,不仅应用于酯类香料与染料的制备中,还被认为是一种有效的震颤抑制剂。 | |||
T85010 |
Sphingosine (d16:1)
D-erythro-Sphingosine C-16 |
Others | Others |
Sphingosine (d16:1), an unconventional sphingolipid, is synthesized through enzymatic reactions starting with the condensation of myristoyl-CoA and serine by serine palmitoyltransferase long-chain base subunit 3 (SPTLC3), which shows a preference for myristoyl-CoA. This compound is found in minute quantities in its free form in human plasma and as a component of various plasma sphingolipids, such as sphingosine-1-phosphate, ceramides, sphingomyelins, and in brain cerebrosides, albeit at lower co... | |||
T37880 |
OPC-167832
|
Others | Others |
OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-167832 exhibits very low MICs against laboratory strains of M. tuberculosis H37Rv (MIC: 0.0005 μg/ml) and Kurono (MIC: 0.0005 μg/ml) and strains with monoresistance to rifampin (RIF), isoniazid (INH), ethambutol (EMB), streptomycin (STR), and pyrazinamide (PZA) (MIC: 0.00024-0.001 ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8192 |
Pentacosanoic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
Pentacosanoic acid 是戊酸的共轭酸,是 25 碳长链饱和脂肪酸。 | |||
T10024 |
1-Octanol
Octanol,正辛醇 |
Calcium Channel; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
1-Octanol (Octanol) 是一种饱和脂肪醇,是一种 T 型钙通道抑制剂,对天然 T 电流的IC50为 4 μM。它是一种具有类似柴油特性的极具吸引力的生物燃料。 | |||
TN6895 |
Methyl Laurate
月桂酸甲酯,methyl dodecanoate |
Others | Others |
Methyl Laurate (methyl dodecanoate) 是月桂酸的酯化产物,是一种 12 碳饱和脂肪酸。 | |||
T9514 |
1-Dodecanol
|
Endogenous Metabolite | Metabolism |
1-Dodecanol 是内源性代谢产物的一种。 | |||
T8049 |
Pentadecanoic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
Pentadecanoic acid 是一个具有 15 个碳主链的饱和脂肪酸。 | |||
T2908 |
Palmitic acid
Hexadecoic acid,hexadecanoic acid,棕榈酸,Cetylic acid |
HSP; Endogenous Metabolite | Cytoskeletal Signaling; Metabolism |
Palmitic acid (Cetylic acid) 属于天然产物,是一种常见的饱和脂肪酸,在动物、植物和微生物中均存在。Palmitic acid 具有抗肿瘤活性。 | |||
T3732 |
Decanedioic acid
1,10-Decanedioic acid,皮脂酸,Sebacic acid,Sebacinsaure,1,8-Octanedicarboxylic acid |
HIV Protease; Endogenous Metabolite | Metabolism; Microbiology/Virology; Proteases/Proteasome |
Decanedioic acid (Sebacinsaure) 是普通尿酸,与肉毒碱-甲酰乙胺转运酶缺乏和中链酰辅酶缺乏症有关。 | |||
T5942 |
Docosanoic acid
Behenic Acid,山嵛酸 |
DNA/RNA Synthesis; Endogenous Metabolite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Docosanoic acid (Behenic Acid) 是一种较难吸收的饱和脂肪酸,能提高人类胆固醇水平。 | |||
T4775 |
Arachidic acid
eicosanoic acid,Icosanoic Acid,花生酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Arachidic acid (Icosanoic Acid) 是一种存在于所有哺乳动物细胞中的长链脂肪酸,通常酯化为膜磷脂,是人体组织中丰富的多不饱和脂肪酸之一。 | |||
T5237 |
Hexadecanedioic acid
1,14-Tetradecanedicarboxylic acid,1,16-Hexadecanedioic acid,Thapsic acid,十六碳二酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Hexadecanedioic acid (1,16-Hexadecanedioic acid) 能够与 Sepharose 4B 以共价键结合,比染料树脂更具有特异性,用于去除血浆中的血清白蛋白。 | |||
TN6953 |
Lignoceric Acid
二十四烷酸,tetracosanoic acid |
Endogenous Metabolite | Metabolism |
Lignoceric Acid (tetracosanoic acid) 是一种 24 碳饱和 (24:0) 脂肪酸,在发育中的大脑中合成,也是一种木质素生产的副产品。它能够用于研究 Zellweger 脑-肝-肾综合征和肾上腺脑白质营养不良。 | |||
TQ0194 |
trans-Vaccenic acid
TVA,(11E)-octadec-11-enoic acid,11E)-octadec-11-enoic acid |
Apoptosis; Endogenous Metabolite | Apoptosis; Metabolism |
trans-Vaccenic acid 是前体物质,可在瘤胃中合成饱和脂肪酸,在组织水平合成共轭亚油酸。trans-Vaccenic acid 通过线粒体介导的凋亡途径抑制人鼻咽癌细胞增殖并诱导其凋亡 | |||
TN6972 |
Methyl pentadecanoate
|
Others | Others |
Methyl pentadecanoate 是一种天然产物。它是由肉豆蔻酸酯化得到的饱和脂肪酸甲酯。肉豆蔻酸甲酯(Methyl myristate) 在 B16F10 黑色素瘤中显示出高黑色素诱导。 | |||
TN6754 |
1-Nonadecanol
|
Others | Others |
1-Nonadecanol 是一种 Heracleum thomsonii 的超临界二氧化碳精油的成分,也是 Neotinea ustulata 的重要香气化合物。 | |||
T6873 |
Lauric Acid
月桂酸,Dodecylic acid,dodecanoic acid,Vulvic acid,N-Dodecanoic acid |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
Lauric Acid (Dodecylic acid) 是一种有抗菌活性的中链脂肪酸,对P. acnes,S.aureus 和S. epidermidis 的 EC50值分别为 2,6,4 μg/mL。 | |||
T3949 |
Myristic acid
肉豆蔻酸,Crodacid,Tetradecanoic acid,n-Tetradecanoic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Myristic acid (Crodacid) 是饱和的 14 碳脂肪酸,存在于大多数动物、植物的脂肪中,特别是乳脂,椰子油,棕榈油和肉豆蔻油。 | |||
T3950 |
Tridecanoic acid
n-Tridecoic Acid,n-Tridecanoic Acid,十三酸,Tridecylic Acid |
Others; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology; Others |
Tridecanoic acid (Tridecylic Acid) 是一种存在于乳制品中的 13 碳饱和脂肪酸,也是正十六烷厌氧生物降解的产物。 它是磷脂酶 A2 的底物,可作为抗粘剂和抗生物膜剂,用于研究细菌感染。它抑制大肠杆菌的持久性和生物膜形成。 | |||
T1165 |
Ethionamide
Bayer 5312,乙硫异烟胺,2-ethylthioisonicotinamide,Ethinamide |
Dehydrogenase; CAT; Antibacterial; Antibiotic | Metabolism; Microbiology/Virology; oxidation-reduction |
Ethionamide (2-ethylthioisonicotinamide) 是一种抗结核抗生素。 | |||
T0884 |
1-Docosanol
Behenic alcohol,Behenyl alcohol,n-Docosanol,二十二醇,Docosanol |
Antifection; HSV | Microbiology/Virology |
1-Docosanol (Behenic alcohol) 是一种具有抗病毒活性的饱和 22 碳脂肪醇,局部用于治疗复发性单纯性唇疱疹发作并缓解相关疼痛并可能有助于更快地治愈疮。 | |||
T4944 |
Nervonic acid
cis-15-Tetracosenoic acid,神经酸,Selacholeic acid |
Endogenous Metabolite | Metabolism |
Nervonic acid (Selacholeic acid) 是在髓磷脂生物合成中很重要的单不饱和脂肪酸。 | |||
T81026 |
Tectorigenin sodium sulfonate
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Others | Others |
Tectorigenin sodium sulfonate,一种经鸢尾黄素磺化并与饱和盐水混合得到的化合物,拥有高水溶性及优良抗氧化特性。 | |||
T83346 |
3-Oxooctadecanoic acid
3-Oxostearic acid |
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3-Oxooctadecanoic acid (3-Oxostearic acid) 为饱和脂肪酸 (SFA) 类别下的一种化合物,作为脂肪酸生物合成过程中的中间产物,其通过酶催化自丙二酸转化得到。 | |||
T37219 |
N-Palmitoyl Glycine
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Others | Others |
The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolamide (AEA; anandamide). N-palmitoyl glycine (PalGly) contains an 18-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. Endogenously produced in rat skin and spinal cord, PalGly is present in 100... |
Cat. No. | Product Name | Species | Expression System |
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TMPY-01460 |
ABHD4 Protein, Human, Recombinant (His)
abhydrolase domain containing 4,ABH4 |
Human | Baculovirus Insect Cells |
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipa... | |||
TMPH-01410 |
GPR84 Protein, Human, Recombinant (hFc)
G-protein coupled receptor 84,GPR84,Inflammation-related G-p... |
Human | P. pastoris (Yeast) |
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. GPR84 Protein, Human, Recom... | |||
TMPH-02618 |
CYP2E1 Protein, Mouse, Recombinant (His)
Cyp2e1,Cytochrome P450 2E1,Cytochrome P450-J,4-nitrophenol 2... |
Mouse | E. coli |
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be invo... | |||
TMPH-00433 |
Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc)
Extracellular fatty acid-binding protein,Lipocalin Q83 |
Coturnix coturnix japonica | E. coli |
Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long chain saturated fatty acids such as steraic acid. May act as an antibacterial factor, through dual ligand specificity, both as a siderophore-sequestrating molecule and a lysophosphatidic acid (LPA) sensor. Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc) is expr... | |||
TMPH-01624 |
GBA Protein, Human, Recombinant
Lysosomal glycosylceramidase,Acid beta-glucosidase,Alglucera... |
Human | E. coli |
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction tha... | |||
TMPH-01623 |
GBA Protein, Human, Recombinant (His & Myc & SUMO)
Lysosomal acid glucosylceramidase,GBA1,Lysosomal galactosylc... |
Human | E. coli |
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction tha... | |||
TMPY-01345 |
ACBD6 Protein, Human, Recombinant (His)
acyl-CoA binding domain containing 6 |
Human | Baculovirus Insect Cells |
Human acyl-coenzyme A binding domain-containing member 6 (ACBD6) is a modular protein that carries an acyl-CoA binding domain at its N terminus and two ankyrin motifs at its C terminus. In mammals, there are six members of the acyl-CoA binding domain-containing (ACBD) family, and their annotation is not uniform. All six ACBD proteins contain an ACB domain at the N terminus, but they do not share significant homology at the C-terminal region. ACBD6 is a 32 kDa protein that is predicted by sequenc... | |||
TMPH-02690 |
PLA2G10 Protein, Mouse, Recombinant (His & Myc)
Pla2g10,Group X secretory phospholipase A2,Phosphatidylcholi... |
Mouse | E. coli |
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density li... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T39423 |
Palmitic acid-13C sodium
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Sodium palmitate-13C is the 13C-labeled variant of palmitic acid, a long-chain saturated fatty acid prevalent in animals and plants. This compound has been shown to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells. | |||
T40980 |
Palmitic acid-13C2
Palmitic acid-13C2 |
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Palmitic acid-13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. | |||
T40141 |
Palmitic acid-13C16 sodium
Palmitic acid-13C16 sodium |
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Palmitic acid-13C16 sodium, a 13C-labeled form of the naturally occurring saturated fatty acid Palmitic acid sodium, is prevalent in animals and plants. This compound can trigger the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells. | |||
T35697 |
Lauric Acid-13C
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Lauric acid-13C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil.1Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.2 | |||
TMID-0264 |
Docosanoic-7,7,8,8-d4 Acid
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Docosanoic-7,7,8,8-d4 Acid 是 Docosanoic Acid 的氘代化合物。Docosanoic Acid 的 CAS 号为 112-85-6。Docosanoic acid 是一种较难吸收的饱和脂肪酸,能提高人类胆固醇水平。 | |||
T35789 |
Palmitic acid-1-13C
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Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a... | |||
T35790 |
Palmitic acid-1,2,3,4-13C4
Palmitic Acid-13C (C1, C2, C3, and C4 labeled) |
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Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula... | |||
TMID-0177 |
Palmitic acid-16,16,16-d3
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Palmitic acid-16,16,16-d3 是 Palmitic acid 的氘代化合物。Palmitic acid 的 CAS 号为 57-10-3。Palmitic acid 是在动物、植物和微生物中发现的最常见的饱和脂肪酸,具有抗肿瘤活性。它可诱导小鼠颗粒细胞中葡萄糖调节蛋白 78 和 CCAAT/增强子结合蛋白同源蛋白的表达。 | |||
T35791 |
Palmitic acid-13C
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Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ... | |||
T35698 |
Octanoic Acid-13C
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Octanoic acid-13C is intended for use as an internal standard for the quantification of octanoic acid by GC- or LC-MS. Octanoic acid is a medium-chain saturated fatty acid. It has been found in Teleme cheeses made from goat, ovine, or bovine milk.1 Octanoic acid is active against the bacteria S. mutans, S. gordonii, F. nucleatum, and P. gingivalis (IC80s = <125, <125, 1,403, and 2,294 μM, respectively).2 Levels of octanoic acid are increased in the plasma of patients with medium-chain acyl-CoA d... |