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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0192 |
Levetiracetam
左乙拉西坦,UCB L059,SIB-S1 |
DNA Methyltransferase; Others; Calcium Channel | Chromatin/Epigenetic; Membrane transporter/Ion channel; Metabolism; Others |
Levetiracetam (SIB-S1) 是一种化学增敏剂,增强 Temozolomide 对胶质母细胞瘤干细胞增殖和凋亡的影响。它调节 HDAC 水平,最终使 MGMT 沉默从而提高 Temozolomide 的有效性。它是一种抗癫痫药,可结合突触小泡蛋白 SV2A。 | |||
T39069 |
UCB-J
|
Others | Others |
UCB-J is a radioligand for the synaptic vesicle protein 2A (SV2A), utilized in positron emission tomography (PET)[4]. | |||
T16869 |
Seletracetam
Ucb 44212 |
Others | Others |
Seletracetam is an analog of the antiepileptic agent Levetiracetam. Seletracetam is a small molecule SV2A modulator for the research of epilepsy. | |||
T39428 |
Seletracetam lithium bromide
Ucb 44212 lithium bromide |
Others | Others |
Seletracetam (Ucb 44212) lithium bromide is a SV2A modulator, intended for epilepsy research. It is an analog of Levetiracetam, an antiepileptic agent. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00304 |
SV2A Protein, Bovine, Recombinant (His & Myc)
Synaptic vesicle glycoprotein 2A,p87,SV |
Bovine | HEK293 Cells |
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. SV2A Protein, Bovine, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 22.8 kDa and the accession number is Q29397. | |||
TMPH-03741 |
BoNT/F Protein, Clostridium botulinum, Recombinant (His)
Bontoxilysin-F,BoNT/F,botF,Botulinum neurotoxin type F |
Clostridium botulinum | E. coli |
Botulinum toxin causes flaccid paralysis by inhibiting neurotransmitter (acetylcholine) release from the presynaptic membranes of nerve terminals of the eukaryotic host skeletal and autonomic nervous system, with frequent heart or respiratory failure. Precursor of botulinum neurotoxin F which may have 2 coreceptors; complex polysialylated gangliosides found on neural tissue and specific membrane-anchored proteins found in synaptic vesicles. Receptor proteins are exposed on host presynaptic cell ... |