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18

抑制剂 & 化合物

9

天然产物

9

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T38567	STh
	STh, also known as Escherichia coli heat-stable toxin, is a 19 amino acid polypeptide containing three disulfide bridges. It serves as an antigen of significance in the quest for a comprehensive enterotoxigenic Escherichia coli (ETEC) vaccine.
T38888	Azide-PEG3-Desthiobiotin Azide-PEG3-Desthiobiotin	Others	Others
	Azide-PEG3-Desthiobiotin 是一种属于 PEG 类的PROTAC linker，可用于合成 PROTAC 分子。
T17796	DBCO-PEG4-Desthiobiotin	Others	Others
	DBCO-PEG4-Desthiobiotin is a polyethylene glycol (PEG) derivative utilized as a linker for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
T80625	Fosthiazate	Others	Others
	Fosthiazate是一种作用机制为通过抑制包括根结线虫(Meloidogyne spp.)、球孢线虫(Globodera spp.)以及短体线虫(Pratylenchus spp.)在内的多种植物寄生线虫乙酰胆碱酯酶合成的广谱杀线虫剂。
T126372	Osthenone	Others	Others
	Osthenone 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126372。
T61423	Transthyretin-IN-1	Others	Others
	Transthyretin-IN-1 (Compound 1d) is a potent inhibitor of transthyretin (TTR) fibril formation, making it a valuable tool for investigating Alzheimer’s disease [1].
T10161	Antiasthmatic Compound 1	Others	Others
	Antiasthmatic Compound 1 is an antiasthmatic agent.
T18412	N-Desthiobiotin-N-bis(PEG4-NHS ester)	Others	Others
	N-Desthiobiotin-N-bis(PEG4-NHS ester) is a polyethylene glycol (PEG) derived linker used for synthesizing PROTACs[1].
T39832	Amine-PEG4-Desthiobiotin Amine-PEG4-Desthiobiotin	Others	Others
	Amine-PEG4-Desthiobiotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T77878	Desthiobiotin-Iodoacetamide	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	Desthiobiotin-Iodoacetamide 可应用于ADC Linker。该化合物亦可作为探针，用于标记经草甲素（Oridonin）处理的细胞裂解物。
T17339	(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin	Others	Others
	(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin is a polyethylene glycol (PEG)-based PROTAC linker utilized for the synthesis of PROTACs.
T70748	Bisthianostat	Others	Others
	Bisthianostat, also known as CF367 or CF367;-C, is a novel Orally Efficacious Pan-HDAC Inhibitor. Bisthianostat selectively binds to and inhibits HDACs, which inhibits deacetylation of histone proteins and leads to the accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, the inhibition of tumor oncogene transcription, and the selective transcription of tumor suppressor genes. This prevents cell division, induces cell cycle arrest and apoptosis. Thi...
T10508	Asthma relating compound 1	Others	Others
	Asthma relating compound 1 is an anti-asthmatic compound.
T18413	N-Desthiobiotin-N-bis(PEG4-t-butyl ester)	Others	Others
	N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based linker compound employed for the synthesis of PROTACs, which are bifunctional molecules designed for targeted protein degradation[1].
T125639	Pestheic acid	Others	Others
	Pestheic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125639，CAS号为 165905-02-2。
T39364	Desthiobiotin-PEG4-propargyl Desthiobiotin-PEG4-propargyl	Others	Others
	Desthiobiotin-PEG4-propargyl is a PEG-coupled PROteolysis TArgeting Chimeric (PROTAC) linker, employed for PROTAC synthesis.
T39728	Amine-PEG3-Desthiobiotin Amine-PEG3-Desthiobiotin	Others	Others
	Amine-PEG3-Desthiobiotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T71261	Arsthinol	Others	Others
	Arsthinol is an antiprotozoal agent which may have anti-cancer activity. It was found that arsthinol, a trivalent organoarsenic compound (dithiarsolane), has been active in vitro on leukemia cell lines and offers a better therapeutic index than arsenic trioxide, as estimated by the ratio LD50/IC50. Arsthinol induced growth inhibition of NB4 cells at lower concentration (IC50 (concentration inhibiting growth by 50%) = 0.78 +/- 0.08 micromol/l after 24 h) than As(2)O(3) (IC50 = 1.60 +/- 0.23 micro...

化合物

Cat.No: T38567

Azide-PEG3-Desthiobiotin

Cat.No: T38888

Synonym: Azide-PEG3-Desthiobiotin

Target: Others

DBCO-PEG4-Desthiobiotin

Cat.No: T17796

Target: Others

Cat.No: T80625

Target: Others

Cat.No: T126372

Target: Others

Transthyretin-IN-1

Cat.No: T61423

Target: Others

Antiasthmatic Compound 1

Cat.No: T10161

Target: Others

N-Desthiobiotin-N-bis(PEG4-NHS ester)

Cat.No: T18412

Target: Others

Amine-PEG4-Desthiobiotin

Cat.No: T39832

Synonym: Amine-PEG4-Desthiobiotin

Target: Others

Desthiobiotin-Iodoacetamide

Cat.No: T77878

Target: Others, ADC Linker

(5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin

Cat.No: T17339

Target: Others

Cat.No: T70748

Target: Others

Asthma relating compound 1

Cat.No: T10508

Target: Others

N-Desthiobiotin-N-bis(PEG4-t-butyl ester)

Cat.No: T18413

Target: Others

Cat.No: T125639

Target: Others

Desthiobiotin-PEG4-propargyl

Cat.No: T39364

Synonym: Desthiobiotin-PEG4-propargyl

Target: Others

Amine-PEG3-Desthiobiotin

Cat.No: T39728

Synonym: Amine-PEG3-Desthiobiotin

Target: Others

Cat.No: T71261

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN4919	Rosthornin A	Others	Others
	Rosthornin A 是一种分离自 Rabdosia rosthornii 干叶的醚提取的 ent-kaurene diterpenoid 化合物。
TN1120	Osthenol	MAO; Monoamine Oxidase	Metabolism; Neuroscience
	Osthenol 是一种前酰化香豆素，从独活干根中分离得到。它对重组 hMAO-A 具有潜在的选择性抑制作用，IC50=0.74 µM，对 hMAO-A 和 hMAO-B 表现出较高的选择性指数。它是一种可逆的，选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂 (Ki=0.26 µM)。
T2848	Osthole Osthol,NSC 31868,蛇床子素,Ostol	Apoptosis; HBV; Parasite; Histamine Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Osthole (Osthol) 是一种天然抗组胺药替代试剂，可刺激成骨细胞增殖和分化。它可抑制组胺 H1受体活性，还可抑制细胞培养物中 HBV 的分泌。
T19259	D-Desthiobiotin	Endogenous Metabolite	Metabolism
	D-Desthiobiotin 是一种生物素衍生物，用于蛋白质层析和亲和层析，也用于蛋白质和细胞的标记、检测和分离。
T10838	Closthioamide	Antibacterial	Microbiology/Virology
	Closthioamide is a potent inhibitor of bacterial DNA gyrase and highly active against MRSA, Ec, VRE, and Mv (MICs: 0.58 μM, 9.00 μM, 0.58 μM and 72.03 μM).
TN4920	Rosthornin B	Others	Others
	Rosthornin B 是分离自 Rabdosia rosthornii 干叶的醚提取物的一种ent-kaurene diterpenoid 化合物。
TN3665	cis-Dehydroosthol	Others	Others
	cis-Dehydroosthol是一种天然产物，属于芸香科九里香属，其产品编号为 TN3665，CAS号为 109741-40-4。cis-Dehydroosthol可用作对照参考。
TN7465	2'E-3'-formaldehydylosthole	Others	Others

TN2021	Osthol hydrate 8-(3-羟基-3-甲基丁基)-7-甲氧基-2H-1-苯并吡喃-2-酮,水合蛇床子素	Others	Others
	Osthol hydrate is a natural product

天然产物

Cat.No: TN4919

Target: Others

Cat.No: TN1120

Target: MAO, Monoamine Oxidase

Cat.No: T2848

Synonym: Osthol,NSC 31868,蛇床子素,Ostol

Target: Apoptosis, HBV, Parasite, Histamine Receptor

D-Desthiobiotin

Cat.No: T19259

Target: Endogenous Metabolite

Cat.No: T10838

Target: Antibacterial

Cat.No: TN4920

Target: Others

cis-Dehydroosthol

Cat.No: TN3665

Target: Others

2'E-3'-formaldehydylosthole

Cat.No: TN7465

Target: Others

Cat.No: TN2021

Synonym: 8-(3-羟基-3-甲基丁基)-7-甲氧基-2H-1-苯并吡喃-2-酮,水合蛇床子素

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00635	Heat-stable enterotoxin ST-IA/ST-P Protein, E. coli, Recombinant (GST) STh,sta1,Heat-stable enterotoxin ST-IA/ST-P,STp	E. coli	E. coli
	Toxin which activates the particulate form of guanylate cyclase and increases cyclic GMP levels within the host intestinal epithelial cells.
TMPH-01566	Isthmin-1/ISM1 Protein, Human, Recombinant (His) Isthmin-1,ISM1	Human	E. coli
	Acts as an angiogenesis inhibitor.
TMPY-01756	Transthyretin Protein, Human, Recombinant (His) PALB,HEL111,CTS,transthyretin,CTS1,HsT2651,TBPA	Human	HEK293 Cells
	Transthyretin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is E9KL36.
TMPK-01090	Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His) Prealbumin,TBPA,CTS,HEL111,Transthyretin,TTR,ATTR,C...	Cynomolgus	HEK293 Cells
	Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial amyloidotic polyneuropathy and cardiomyopathy. Normal TTR can also aggregate and deposit in the heart of old people and in preeclampsia placental tissue.
TMPH-02242	Transthyretin Protein, Human, Recombinant (hFc & Myc) TTR,ATTR,Transthyretin,Prealbumin,TBPA	Human	HEK293 Cells
	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
TMPH-02332	Isthmin-2/ISM2 Protein, Human, Recombinant (His & Myc) Thrombospondin type-1 domain-containing protein 3,Thrombospo...	Human	E. coli
	N/A. Isthmin-2/ISM2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 61.8 kDa and the accession number is Q6H9L7.
TMPY-04919	Transthyretin Protein, Mouse, Recombinant (His) AI787086,prealbumin,D17860,AA408768,transthyretin	Mouse	HEK293 Cells
	Transthyretin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is P07309.
TMPH-02947	Transthyretin Protein, Mouse, Recombinant Prealbumin,Transthyretin,Ttr	Mouse	E. coli
	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.5 kDa and the accession number is P07309.
TMPH-02946	Transthyretin Protein, Mouse, Recombinant (His & SUMO) Transthyretin,Prealbumin,Ttr	Mouse	E. coli
	Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. Transthyretin Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.6 kDa and the accession number is P07309.

重组蛋白

Heat-stable enterotoxin ST-IA/ST-P Protein, E. coli, Recombinant (GST)

Cat.No: TMPH-00635

Species: E. coli

Expression System: E. coli

Isthmin-1/ISM1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01566

Species: Human

Expression System: E. coli

Transthyretin Protein, Human, Recombinant (His)

Cat.No: TMPY-01756

Species: Human

Expression System: HEK293 Cells

Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01090

Species: Cynomolgus

Expression System: HEK293 Cells

Transthyretin Protein, Human, Recombinant (hFc & Myc)

Cat.No: TMPH-02242

Species: Human

Expression System: HEK293 Cells

Isthmin-2/ISM2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02332

Species: Human

Expression System: E. coli

Transthyretin Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04919

Species: Mouse

Expression System: HEK293 Cells

Transthyretin Protein, Mouse, Recombinant

Cat.No: TMPH-02947

Species: Mouse

Expression System: E. coli

Transthyretin Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02946

Species: Mouse

Expression System: E. coli

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