5
1
1740
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4216 |
STAT5-IN-1
STAT5 Inhibitor |
STAT | JAK/STAT signaling; Stem Cells |
STAT5-IN-1 (STAT5 Inhibitor) 是STAT5的抑制剂,对 STAT5β 亚型的IC50值为 47 μM。 | |||
T35407 |
Ζ-Stat
|
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
ζ-Stat 是非典型的、特异性的PKC-ζ抑制剂,IC50为 5 μM。ζ-Stat 能够减少黑色素瘤细胞系的增殖并诱导细胞凋亡,在体外显示除抗肿瘤活性。 | |||
T74800 |
HAT-SIL-TG-1&AT
|
Others | Others |
HAT-SIL-TG-1&AT 是一种 Janus 酪氨酸激酶 (JAK) 抑制剂,具有抗肿瘤作用。HAT-SIL-TG-1&AT 是缺氧激活的前药,可抑制肿瘤组织中的JAK-STAT 信号传导。HAT-SIL-TG-1&AT 在低氧条件下抑制 HEL 细胞增殖并下调磷酸化的STAT3/5。 | |||
T75535 |
5-epi-Arvestonate A
|
Others | Others |
5-epi-Arvestonate A是一种从(Seriphidium transiliense)绢毛菊中提取的倍半萜化合物,能够通过激活(MITF)小眼相关转录因子和酪氨酸酶家族基因来促进黑色素的产生。此外,5-epi-Arvestonate A还能通过JAK/STAT信号通路,抑制永生化人角化细胞(HaCaT)中IFN-γ趋化因子的表达。 | |||
T37265 |
15(R)-Lipoxin A4
15(R)-Lipoxin A4,AT-Lipoxin A4 |
Others | Others |
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspirin-triggered formation of 15(R)-HETE from arachidonic acid. [1] [2] 15(R)-LXA4 inhibits LTB4-induced chemotaxis, adherence, and transmigration of neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.[2] [3] The anti-inflammatory effects of aspirin may... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1237 |
3-O-Methylgallic acid
3,4-Dihydroxy-5-methoxybenzoic acid,3-O-甲基没食子酸 |
Apoptosis; NF-κB; OCT; DNA/RNA Synthesis; STAT | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; JAK/STAT signaling; Membrane transporter/Ion channel; NF-κB; Stem Cells |
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) 是一种花青素代谢产物,具有强大的抗氧化能力。它还诱导细胞凋亡并具有抗癌作用,可抑制 Caco-2 细胞增殖,IC50值为 24.1 μM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05308 |
CD45 Protein, Human, Recombinant (aa 1-529, His)
GP180,B220,L-CA,protein tyrosine ... |
Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5. | |||
TMPY-04451 |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
AMPK, AMPK(α1, β1, γ1) |
Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1. | |||
TMPY-03878 |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,in |
Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-02030 |
CD82 Protein, Human, Recombinant (His)
CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T... |
Human | HEK293 Cells |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud... | |||
TMPY-01894 |
SIGIRR Protein, Human, Recombinant (His)
TIR8,single immunoglobulin and toll-in... |
Human | HEK293 Cells |
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1. | |||
TMPY-01247 |
FLT3 Protein, Human, Recombinant (T227M, His)
FLK2,FLK-2,CD135,STK1,fms-related... |
Human | HEK293 Cells |
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1. | |||
TMPY-02779 |
Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)
thyroid peroxidase,MSA,TPX,TDH2A |
Human | Baculovirus Insect Cells |
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i... | |||
TMPY-03290 |
HGF Protein, Mouse, Recombinant
hepatocyte growth factor (hepapoietin A,NK1 |
Mouse | HEK293 Cells |
HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1. | |||
TMPY-04970 |
TIGIT Protein, Human, Recombinant (hFc)
WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom... |
Human | HEK293 Cells |
TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1. | |||
TMPY-01147 |
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)
RSPO,CRISTIN3,R-spondin 1 |
Human | HEK293 Cells |
R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1. | |||
TMPY-04346 |
PD-L2 Protein, Human, Recombinant (His)
PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed... |
Human | HEK293 Cells |
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1. | |||
TMPY-00947 |
VCAM-1 Protein, Human, Recombinant (hFc)
INCAM-100,CD106,VCAM-1,v... |
Human | HEK293 Cells |
VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1. | |||
TMPY-01949 |
CD19 Protein, Human, Recombinant (His)
CD19 molecule,B4,CVID3 |
Human | HEK293 Cells |
CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1. | |||
TMPY-04165 |
FGFR3 Protein, Human, Recombinant (His)
JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33... |
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1. | |||
TMPY-00820 |
IgG1 Fc Protein, Human, Recombinant (C103S)
Ighg1,IgG1 Fc |
Human | HEK293 Cells |
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1. | |||
TMPY-01146 |
Insulin Receptor Protein, Human, Recombinant (long isoform, His)
HHF5,CD220,insulin receptor |
Human | HEK293 Cells |
Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1. | |||
TMPY-04348 |
CTLA-4 Protein, Human, Recombinant (His)
ALPS5,CD152,GRD4,cytotoxic T-lymp... |
Human | HEK293 Cells |
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1. | |||
TMPY-02813 |
ErbB4 Protein, Human, Rhesus, Recombinant (His)
erb-b2 receptor tyrosine kinase 4 |
Human,Rhesus | HEK293 Cells |
ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1. | |||
TMPY-05220 |
TSLP Protein, Human, Recombinant (R127A & R130S, His)
thymic stromal lymphopoietin |
Human | HEK293 Cells |
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1. | |||
TMPY-01827 |
CD30/TNFRSF8 Protein, Human, Recombinant (His)
D1S166E,tumor necrosis factor receptor sup... |
Human | HEK293 Cells |
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1. | |||
TMPY-00853 |
IL-1RA Protein, Human, Recombinant
DIRA,IL1RA,interleukin 1... |
Human | E. coli |
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1. | |||
TMPY-01850 |
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC11987... |
Human | HEK293 Cells |
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... | |||
TMPY-02245 |
SNAP-25 Protein, Human, Recombinant (His)
synaptosomal-associated protein, 25kDa,SEC... |
Human | E. coli |
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp... | |||
TMPY-00203 |
LOXL2 Protein, Mouse, Recombinant (His)
1110004B06Rik,4930526G |
Mouse | HEK293 Cells |
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act... | |||
TMPY-01851 |
CD73 Protein, Human, Recombinant (His)
eN,NT5,E5NT,NT,5'-nucleotidase, e... |
Human | HEK293 Cells |
CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1. | |||
TMPY-01281 |
ACVR2B Protein, Mouse, Recombinant (His)
ActRIIB,activin A receptor, type IIB,49305... |
Mouse | HEK293 Cells |
ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1. | |||
TMPY-03967 |
BTN3A3 Protein, Human, Recombinant (His)
BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3... |
Human | HEK293 Cells |
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1. | |||
TMPY-02525 |
RGMA Protein, Human, Recombinant (His)
repulsive guidance molecule family member a,RGM |
Human | HEK293 Cells |
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form... | |||
TMPY-05208 |
PD-L1 Protein, Human, Recombinant
CD274 molecule,PDCD1L1,PD-L1,PDL<... |
Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-00978 |
Progranulin Protein, Human, Recombinant (His)
PGRN,PCDGF,CLN11,Granulin,GP88,GE... |
Human | HEK293 Cells |
Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1. | |||
TMPY-03407 |
NQO1 Protein, Human, Recombinant (His)
NAD(P)H dehydrogenase, quinone 1,NMORI,DIA... |
Human | E. coli |
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex... | |||
TMPY-01258 |
IL-13RA1 Protein, Human, Recombinant (His)
NR4,interleukin 13 receptor, alph... |
Human | HEK293 Cells |
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1. | |||
TMPY-03531 |
PSGL-1/CD162 Protein, Human, Recombinant (His)
selectin P ligand,PSGL-1,PSGL1,CD... |
Human | HEK293 Cells |
PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1. | |||
TMPY-01883 |
EPOR Protein, Human, Recombinant (His)
erythropoietin receptor,EPO-R |
Human | HEK293 Cells |
EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1. | |||
TMPY-01862 |
IL-4 Protein, Human, Recombinant
Interleukin-4,IL-4,BCGF1,白细胞介素, |
Human | E. coli |
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1. | |||
TMPY-06418 |
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
R-spondin 2,CRISTIN2 |
Human | HEK293 Cells |
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1. | |||
TMPY-04333 |
LRRC15 Protein, Human, Recombinant (hFc)
leucine rich repeat containing |
Human | HEK293 Cells |
LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1. | |||
TMPY-02033 |
CD44 Protein, Human, Recombinant (His)
CD44 molecule (Indian blood group),IN,MC |
Human | HEK293 Cells |
CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1. | |||
TMPY-04104 |
LIF Protein, Human, Recombinant
CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HI... |
Human | HEK293 Cells |
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1. | |||
TMPY-04939 |
LAG-3 Protein, Human, Recombinant
LAG-3,lymphocyte-activation gene 3,CD223 |
Human | HEK293 Cells |
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1. | |||
TMPY-00861 |
IL-33 Protein, Human, Recombinant
IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2... |
Human | E. coli |
IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1. | |||
TMPY-06873 |
FLT3 Ligand Protein, Human, Recombinant
FLT3LG,fms related tyrosine kinase 3 ligan... |
Human | E. coli |
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1. | |||
TMPY-01185 |
DR5/TRAIL R2 Protein, Human, Recombinant (His)
KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis fac... |
Human | HEK293 Cells |
DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1. | |||
TMPY-01938 |
CD98 Protein, Human, Recombinant (His)
4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri... |
Human | HEK293 Cells |
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1. | |||
TMPY-01137 |
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)
erb-b2 receptor tyrosine kinase 2,NEU,ENVW... |
Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1. | |||
TMPY-04826 |
LILRB5/CD85c Protein, Human, Recombinant (His)
leukocyte immunoglobulin like receptor B5,... |
Human | HEK293 Cells |
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig... | |||
TMPY-01744 |
ACVR2A Protein, Human, Recombinant (His)
activin A receptor, type IIA,ACVR2,ACTRII |
Human | HEK293 Cells |
ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1. | |||
TMPK-00887 |
KIR3DL2 Protein, Human, Recombinant (His & Avi)
KIR3DL2,p140,NKAT4,NKAT4A,NKAT4B,CL-5,CD |
Human | HEK293 Cells |
KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linked homodimer. Each chain is composed of three immunoglobulin-like domains and a long cytoplasmic tail containing two immunoreceptor tyrosine-based inhibitory motifs. KIR3DL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The pred... | |||
TMPY-00150 |
IGF2/IGF-II Protein, Human, Recombinant
PP9974,胰岛素样生长因子,C11orf43,IGF-II,in |
Human | P. pastoris (Yeast) |
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumor, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. IGF-2/IGF-II is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in br... | |||
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