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Search Results for " stat "

Targets Recommended: Somatostatin STAT PKC

720

抑制剂 & 化合物

87

天然产物

4

化合物库

72

重组蛋白

28

同位素标记化合物

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Cat. No.	Product Name
L3700	JAK-STAT 化合物库		252 compounds
	252 个 JAK/STAT 靶点相关的小分子化合物的独特集合，用于高通量、高内涵筛选；
L2195	抗前列腺癌化合物库		2070 compounds
	2070 种与前列腺癌相关的化合物，可以用于高通量和高内涵筛选
L2192	抗胰腺癌化合物库		2238 compounds
	2238 种与胰腺癌相关的化合物，可以用于高通量和高内涵筛选；
L3600	细胞因子抑制剂库		604 compounds
	604 个与细胞因子紧密相关的化合物集合，是高通量、高内涵筛选的良好载体；

化合物库

JAK-STAT 化合物库

Cat.No: L3700

Compounds: 252

抗前列腺癌化合物库

Cat.No: L2195

Compounds: 2070

抗胰腺癌化合物库

Cat.No: L2192

Compounds: 2238

细胞因子抑制剂库

Cat.No: L3600

Compounds: 604

Cat. No.	Product Name	Target	Signaling Pathways
T35407	Ζ-Stat	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	ζ-Stat 是非典型的、特异性的PKC-ζ抑制剂，IC50为 5 μM。ζ-Stat 能够减少黑色素瘤细胞系的增殖并诱导细胞凋亡，在体外显示除抗肿瘤活性。
T40395	ζ-Stat trisodium NSC37044 trisodium,ζ-Stat trisodium	Others	Others
	ζ-Stat trisodium (NSC37044 trisodium) is a potent and selective inhibitor of protein kinase C-ζ (PKC-ζ), exhibiting an IC50 of 5 μM. It effectively suppresses the proliferation of melanoma cell lines and promotes apoptosis. Moreover, ζ-Stat trisodium demonstrates notable antitumor activity in vitro.
T78607	JAK-STAT-IN-1	JAK; STAT	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	JAK-STAT-IN-1 是一种特异性 JAK-STAT 抑制剂，适用于研究自身免疫性疾病。
T4216	STAT5-IN-1 STAT5 Inhibitor	STAT	JAK/STAT signaling; Stem Cells
	STAT5-IN-1 (STAT5 Inhibitor) 是STAT5的抑制剂，对 STAT5β 亚型的IC50值为 47 μM。
T13009	STAT3-IN-1	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	STAT3-IN-1 是一种选择性的、口服有效的 STAT3的强效抑制剂，可诱导肿瘤细胞凋亡，其在 HT29 和MDA-MB 231 细胞中的IC50值分别为1.82 μM 和2.14 μM。
T16940	STAT5-IN-2	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	STAT5-IN-2 是一种具有抗白血病作用的 STAT5 抑制剂（EC50：在 K562 和 KU812 细胞中分别为 9 μM 和 5 μM）。
T28865	STAT3-IN-B9 STAT3 IN B9,B9	STAT	JAK/STAT signaling; Stem Cells
	STAT3-IN-B9 (B9) 是异常 STAT3 激活的抑制剂，可抑制 MDA-MB-468、MDA-MB-231 和 DU145 等肿瘤细胞的增殖。
T3708	BP-1-102	STAT	JAK/STAT signaling; Stem Cells
	BP-1-102 是可口服的转录因子Stat3小分子抑制剂，IC50值为 6.8 μM。
TQ0052	SH5-07	STAT	JAK/STAT signaling; Stem Cells
	SH5-07 是一种基于异羟肟酸的 Stat3 抑制剂，IC50值为 3.9 μM。
T6669	SH-4-54	STAT	JAK/STAT signaling; Stem Cells
	SH-4-54 是有效小分子非磷酸化 STAT3 抑制剂，与 STAT3 和 STAT5 结合的 KD 值分别为 300 和 464 nM。
T62491	STAT3-IN-13	STAT	JAK/STAT signaling; Stem Cells
	STAT3-IN-13 是一种有效的 STAT3 抑制剂。STAT3-IN-13 具有抗增殖和抗癌活性，通过与 STAT3 SH2 结构域结合发挥作用。STAT3-IN-13 抑制 STAT3 Y705 的磷酸化，诱导细胞凋亡，抑制肿瘤细胞的生长和转移。STAT3-IN-13 可用于研究乳腺癌和肝癌。
T61030	STAT3-IN-11	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	STAT3-IN-11 是一种选择性 STAT3 抑制剂，对 STAT3pTyr705位点的磷酸化和Survivin 的磷酸化有抑制作用。STAT3-IN-11 促使癌细胞凋亡，是治疗癌症的候选化合物。
T79185	STAT6-IN-2	STAT	JAK/STAT signaling; Stem Cells
	STAT6-IN-2 (Comp R-84) 是STAT6的一种抑制剂，能够抑制嗜酸粒细胞趋化因子-3的分泌，常用于免疫疾病研究。
T4476	AS1517499	STAT	JAK/STAT signaling; Stem Cells
	AS1517499 是可透过血脑屏障的STAT6磷酸化抑制剂，IC50为 21 nM。
T6537	HO-3867 HO3867	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	HO-3867是一种 STAT3的选择性有效抑制剂，有抗肿瘤活性。
T15582	inS3-54A18	STAT	JAK/STAT signaling; Stem Cells
	inS3-54A18 是一种有效的 STAT3 抑制剂。 inS3-54A18 具有抗癌作用。
T2505	S3I-201 S3I 201,S3I201	STAT	JAK/STAT signaling; Stem Cells
	S3I-201 (S3I-201) 是一种选择性Stat3抑制剂，IC50为 86 μM。
T9339	Stafia-1	STAT	JAK/STAT signaling; Stem Cells
	Stafia-1 是STAT5a 抑制剂，Ki 为 10.9 μM，IC50 为 22.2 μM。它与 STAT5b 和其他 STAT 家族成员相比，显示出高选择性。
T3218	Napabucasin BBI608	STAT	JAK/STAT signaling; Stem Cells
	Napabucasin (BBI608) 是一种口服的 Stat3 和 Y 干细胞活性抑制剂。
T72754	JAK2/STAT3-IN-1	Interleukin	Immunology/Inflammation
	JAK2/STAT3-IN-1 是一种 GP130 抑制剂，具有抗肿瘤作用，可用研究炎症，自身免疫和癌症。
T2168	2-(1,8-naphthyridin-2-yl)phenol	STAT	JAK/STAT signaling; Stem Cells
	2-NP 是选择性的STAT1转录增强剂。它能够增强 IFN-γ 的功能，提高对人乳腺癌和纤维肉瘤细胞增殖的抑制能力。
T2156	WP1066	Apoptosis; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	WP1066 是一种新型JAK2和STAT3抑制剂，对 STAT5 和 ERK1/2 也起作用。它用于研究黑色素瘤、脑癌、实体瘤和中枢神经系统肿瘤治疗。
T8378	AS2863619	CDK; STAT	Cell Cycle/Checkpoint; JAK/STAT signaling; Stem Cells
	AS2863619 是一种口服的细胞周期蛋白依赖性激酶 8 和CDK19抑制剂，抑制CDK8/19可增强STAT5的激活，从而激活 Foxp3 基因。它可将抗原特异性效应子/记忆 T 细胞转换为 Foxp3+调节性 T 细胞，以研究各种免疫疾病。
T6838	FLLL32	Apoptosis; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	FLLL32是一种姜黄素的合成类似物，是JAK2/STAT3的双重抑制剂，具有抗肿瘤癌活性。它作用于乳腺癌细胞，可抑制 IFNα 和 IL-6 诱导的 STAT3 磷酸化。
TP1856	Colivelin	Beta Amyloid; STAT	JAK/STAT signaling; Neuroscience; Stem Cells
	Colivelin 是一种神经保护肽和 STAT3 的激活剂，是一种合成的杂合肽，可增强 humanin (HN) 的神经保护作用。它通过激活 STAT3 在体外抑制神经元死亡，具有潜力用于阿尔茨海默病和缺血性脑损伤的相关研究。
T8546	BD750	JAK; STAT	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	BD750 是免疫抑制剂和JAK3/STAT5的抑制剂，可抑制 IL-2 诱导的、JAK3/STAT5 依赖的 T 细胞增殖，对小鼠和人 T 细胞增殖的IC50值分别为 1.5 和 1.1 μM。
T13950	UC-514321	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	UC-514321 是NSC370284 的结构类似物，靶向STAT3/5并选择性抑制TET1的表达，且活性更高。它有较低的毒性，在体内外均表现出良好的抗急性髓系白血病活性。
T72754L	(R)-JAK2/STAT3-IN-10a	Antiviral	Immunology/Inflammation
	(R)-JAK2/STAT3-IN-10a 是 JAK2/STAT3-IN-1 的R型异构体。JAK2/STAT3-IN-1 是一种 GP130 D1 结构域抑制剂，具有抗肿瘤活性，抑制 JAK2 和 STAT3 磷酸化。(R)-JAK2/STAT3-IN-1 对 GP130 蛋白的 KD 值为3.8μM。
T4650	C188-9 TTI-101	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	C188-9 (TTI-101) 是一种Stat3抑制剂，其Kd 值为 4.7 nM。它诱导 AML 细胞系和原代标本凋亡，抑制原代 AML 细胞集落形成。它抑制 G-CSF 诱导的 STAT3 激活和 STAT3 依赖性基因表达。
T11807	L002	Others; Histone Acetyltransferase; STAT	Chromatin/Epigenetic; JAK/STAT signaling; Others; Stem Cells
	L002 是一种细胞可渗透的，可逆特定性乙酰转移酶 p300(KAT3B)抑制剂，IC50为 1.98 μM。它结合乙酰辅酶 A 口袋并竞争性抑制 FATp300 催化结构域，阻断组蛋白乙酰化和 p53 乙酰化，且抑制 STAT3 激活，有用于高血压引起的心脏肥大和纤维化的研究潜力。
T4234	HJC0152 hydrochloride HJC0152	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	HJC0152 hydrochloride (HJC0152) 是一种信号转导和转录激活因子 3的抑制剂。
T9043	AS1810722	P450; STAT	JAK/STAT signaling; Metabolism; Stem Cells
	AS1810722 是口服有效的STAT6抑制剂，IC50为 1.9 nM。它是一种稠合双环嘧啶衍生物，对有良好的CYP3A4抑制作用，具有用于过敏性疾病，如哮喘和特应性疾病的研究潜力。
T1563	Nifuroxazide Diarlidan,硝呋齐特,Nifuroxazid,Dicoferin,硝呋酚酰肼	Antibacterial; Antibiotic; STAT	JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Nifuroxazide (Diarlidan) 是STAT3抑制剂，具有抗转移和抗癌活性。
T21694	(R)-Lisofylline (R)-Lisophylline	STAT	JAK/STAT signaling; Stem Cells
	(R)-Lisofylline ((R)-Lisophylline) 是溶血磷脂酸酰基转移酶的抑制剂 (IC50 = 0.6 µM)。 (R)-Lisofylline 可中断 IL-12 信号介导的 STAT4 激活，可用于治疗 1 型糖尿病和自身免疫性疾病的研究。
T6308	Stattic STAT3 Inhibitor V	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	Stattic (STAT3 Inhibitor V) 是一种 STAT3 抑制剂 (IC50=5.1 μM)，选择性地抑制 STAT3 活化、二聚化和核转位。Stattic 具有抗肿瘤活性，可诱导细胞凋亡。
T8478	SC-43	Apoptosis; Phosphatase; STAT	Apoptosis; JAK/STAT signaling; Metabolism; Stem Cells
	SC-43 是一种具有口服活性的SHP-1 (PTPN6)激动剂。它是Sorafenib 的衍生物，可抑制STAT3的磷酸化并诱导细胞凋亡，具有抗纤维化和抗癌作用。
T0711L	Niclosamide olamine Niclosamide-olamine,Niclosamide Ethanolamine salt	Antibiotic; STAT; Parasite; Autophagy	Autophagy; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Niclosamide olamine (Niclosamide Ethanolamine salt) 是一种驱虫剂，可破坏寄生虫和动物模型中的线粒体代谢。它可逆地抑制雷帕霉素复合物的哺乳动物靶标，从而抑制STAT3(IC50为 0.25 μM) 并刺激自噬反应。
T3076	GLPG0634 analog GLPG0634 analogue	Tyrosine Kinases; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	GLPG0634 analog (GLPG0634 analogue) 是一种 JAK 广谱性抑制剂，对 JAK1/JAK2/JAK3 的 IC50值为 50 到 200 nM 之间。
T2546	Pimozide R6238,匹莫奇特,匹莫齐特	Potassium Channel; Dopamine Receptor; Adrenergic Receptor; STAT	GPCR/G Protein; JAK/STAT signaling; Membrane transporter/Ion channel; Neuroscience; Stem Cells
	Pimozide (R6238) 是多巴胺受体拮抗剂，对多巴胺 D1、D2 和 D3 受体的 Ki 值分别为 588、1.4 和 2.5 nM。它也是STAT3和STAT5的抑制剂，对 α1 肾上腺素受体也有较高亲和性，Ki 值为 39 nM。
T8476	RSVA405 RSVA 405	AMPK; STAT; Autophagy	Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Stem Cells
	RSVA405 是一种具有口服活性的AMPK 激活剂，EC50值为 1 μM。它也是一种 STAT3 抑制剂，具有抗炎作用，可研究肥胖症。它通过促进 CaMKKβ 依赖的 AMPK 活化，从而抑制mTOR，并促进自噬以增加 Aβ 的降解。
T22424	1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	SC-1 是一种 Sorafenib 的衍生物，可抑制 STAT3磷酸化，通过依赖 SHP-1 的 STAT3失活诱导细胞凋亡，具有抗癌作用。
T0711	Niclosamide BAY2353,Niclocide,氯硝柳胺	Antibiotic; STAT; Parasite	JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Niclosamide (Niclocide) 是一种口服生物可利用的氯化水杨酰苯胺。它通过抑制 DNA 复制，具有驱虫和潜在的抗肿瘤活性。
T8719	SC99	Apoptosis; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	SC99 是一种口服有效选择性STAT3抑制剂，靶向 JAK2-STAT3 途径，抑制血小板活化和聚集，有抗骨髓瘤和抗血栓活性。它结合在 JAK2 的 ATP 结合袋中，抑制 JAK2 和 STAT3 的磷酸化。
T3049	TPCA-1 GW683965,IKK2 Inhibitor IV,TPCA1	Apoptosis; IκB/IKK; STAT	Apoptosis; JAK/STAT signaling; NF-κB; Stem Cells
	TPCA-1 (TPCA1) 是一种选择性IKK-2抑制剂，IC50值为 17.9 nM。它也是反式激活、DNA 结合以及STAT3磷酸化的一种抑制剂。
T62803	STAT3-IN-12	Others	Others
	STAT3-IN-12 是一种 STAT3 的有效信号抑制剂，对 IL-6 诱导的 JAK/STAT3 信号通路的激活具有抑制作用。STAT3-IN-12 对癌细胞生长、迁移具有抑制作用，可阻滞细胞周期并诱导细胞凋亡。STAT3-IN-12 能够用于癌症的相关研究（如肝细胞癌 (HCC) 、食管癌）。
T79662	STAT3-IN-20	STAT	JAK/STAT signaling; Stem Cells
	STAT3-IN-20（Compound 40）是一种选择性地靶向STAT3的SH2结构域，展现了在DU145和MDA-MB-231癌细胞中的抗增殖效果（IC50分别为2.97 μM和3.26 μM），并诱导细胞周期停滞与细胞凋亡。该抑制剂有效抑制了STAT3的磷酸化、核内易位及其下游基因的转录活性（IC50: 0.65 μM）。
T71550	STAT3-IN-8	STAT	JAK/STAT signaling; Stem Cells
	STAT3-IN-8（即化合物H172）是一种高效的STAT3抑制剂，具备在癌症研究中应用的潜力。
T73129	STAT6-IN-1	Others	Others
	STAT6-IN-1（化合物19a）是一种针对STAT6的SH2结构域表现出较高亲和力（IC50=0.028 µM）的STAT6抑制剂。该化合物主要用于研究过敏性肺病、过敏性鼻炎、慢性阻塞性肺病或癌症。
T60765	STAT3-IN-10	Others	Others
	STAT3-IN-10 (A11) 是一种STAT3抑制剂，可直接结合 STAT3 SH2 结构域，抑制肿瘤细胞生长并且诱导肿瘤细胞凋亡 (IC 50 = 5.18 μM)。
T73114	STAT3-IN-7	Others	Others
	STAT3-IN-7 是一种芳基磺胺氮杂环丁烷化合物，是一种具有口服活性的STAT3抑制剂，具有抗癌活性。

化合物

Cat.No: T35407

Target: PKC

ζ-Stat trisodium

Cat.No: T40395

Synonym: NSC37044 trisodium,ζ-Stat trisodium

Target: Others

JAK-STAT-IN-1

Cat.No: T78607

Target: JAK, STAT

Cat.No: T4216

Synonym: STAT5 Inhibitor

Target: STAT

Cat.No: T13009

Target: Apoptosis, STAT

Cat.No: T16940

Target: Apoptosis, STAT

Cat.No: T28865

Synonym: STAT3 IN B9,B9

Target: STAT

Cat.No: T3708

Target: STAT

Cat.No: TQ0052

Target: STAT

Cat.No: T6669

Target: STAT

Cat.No: T62491

Target: STAT

Cat.No: T61030

Target: Apoptosis, STAT

Cat.No: T79185

Target: STAT

Cat.No: T4476

Target: STAT

Cat.No: T6537

Synonym: HO3867

Target: Apoptosis, STAT

Cat.No: T15582

Target: STAT

Cat.No: T2505

Synonym: S3I 201,S3I201

Target: STAT

Cat.No: T9339

Target: STAT

Cat.No: T3218

Synonym: BBI608

Target: STAT

JAK2/STAT3-IN-1

Cat.No: T72754

Target: Interleukin

2-(1,8-naphthyridin-2-yl)phenol

Cat.No: T2168

Target: STAT

Cat.No: T2156

Target: Apoptosis, JAK, STAT

Cat.No: T8378

Target: CDK, STAT

Cat.No: T6838

Target: Apoptosis, JAK, STAT

Cat.No: TP1856

Target: Beta Amyloid, STAT

Cat.No: T8546

Target: JAK, STAT

Cat.No: T13950

Target: Apoptosis, STAT

(R)-JAK2/STAT3-IN-10a

Cat.No: T72754L

Target: Antiviral

Cat.No: T4650

Synonym: TTI-101

Target: Apoptosis, STAT

Cat.No: T11807

Target: Others, Histone Acetyltransferase, STAT

HJC0152 hydrochloride

Cat.No: T4234

Synonym: HJC0152

Target: Apoptosis, STAT

Cat.No: T9043

Target: P450, STAT

Cat.No: T1563

Synonym: Diarlidan,硝呋齐特,Nifuroxazid,Dicoferin,硝呋酚酰肼

Target: Antibacterial, Antibiotic, STAT

(R)-Lisofylline

Cat.No: T21694

Synonym: (R)-Lisophylline

Target: STAT

Cat.No: T6308

Synonym: STAT3 Inhibitor V

Target: Apoptosis, STAT

Cat.No: T8478

Target: Apoptosis, Phosphatase, STAT

Niclosamide olamine

Cat.No: T0711L

Synonym: Niclosamide-olamine,Niclosamide Ethanolamine salt

Target: Antibiotic, STAT, Parasite, Autophagy

GLPG0634 analog

Cat.No: T3076

Synonym: GLPG0634 analogue

Target: Tyrosine Kinases, JAK

Cat.No: T2546

Synonym: R6238,匹莫奇特,匹莫齐特

Target: Potassium Channel, Dopamine Receptor, Adrenergic Receptor, STAT

Cat.No: T8476

Synonym: RSVA 405

Target: AMPK, STAT, Autophagy

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

Cat.No: T22424

Target: Apoptosis, STAT

Cat.No: T0711

Synonym: BAY2353,Niclocide,氯硝柳胺

Target: Antibiotic, STAT, Parasite

Cat.No: T8719

Target: Apoptosis, JAK, STAT

Cat.No: T3049

Synonym: GW683965,IKK2 Inhibitor IV,TPCA1

Target: Apoptosis, IκB/IKK, STAT

Cat.No: T62803

Target: Others

Cat.No: T79662

Target: STAT

Cat.No: T71550

Target: STAT

Cat.No: T73129

Target: Others

Cat.No: T60765

Target: Others

Cat.No: T73114

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN2346	Mogrol	ERK; AMPK; STAT	Chromatin/Epigenetic; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	Mogrol 是罗汉果中的一种天然产物，通过抑制 ERK1/2 和 STAT3 通路，减少 CREB 激活和激活 AMPK 信号传导发挥作用。
T4672	Brevilin A	Apoptosis; Anti-infection; JAK; STAT; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Brevilin A 是从Centipeda minima 中分离的倍半萜内酯，具有抗癌活性。它通过线粒体途径和 PI3K/AKT/mTOR 失活诱导结肠腺癌细胞 CT26 的凋亡和自噬。它是一种选择性JAK-STAT 信号通路抑制剂，通过减弱 JAK 信号和阻塞 STAT3 信号起作用。
T2867	Diosgenin 山药,Nitogenin	STAT	JAK/STAT signaling; Stem Cells
	Diosgenin (Nitogenin) 是盾叶薯蓣中的一种甾体皂苷，是Pdia3/ERp57的激活剂，能够抑制STAT3信号通路。
TN6739	Angoline 6-Methoxyldihydrochelerythrine	IL Receptor; STAT	Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Angoline (6-Methoxyldihydrochelerythrine) 是选择性 IL6/STAT3信号通路的抑制剂，IC50为 11.56 μM。它抑制 STAT3 磷酸化及其靶基因表达，并抑制癌细胞增殖。
T6S0071	Fraxinellone	HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Stem Cells
	Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物，是PD-L1抑制剂，可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1，有用于癌症免疫的潜力。
TN1674	Garcinone D 伽升沃 D	Reactive Oxygen Species; Nrf2; STAT	Immunology/Inflammation; JAK/STAT signaling; Metabolism; NF-κB; Stem Cells
	Garcinone D 是来自山竹的一种呫吨酮，可促进 C17.2 神经干细胞的增殖。它以浓度和时间依赖的方式增加磷酸化信号转导和转录激活因子 3 (p-STAT3)、Cyclin D1 和核因子红细胞 2 相关因子 (Nrf2)、以及血红素加氧酶-1 (HO-1) 的蛋白质水平。
T3913	Saikosaponin D	Estrogen Receptor/ERR; NF-κB; Antibacterial; STAT	Endocrinology/Hormones; JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells
	Saikosaponin D 是一种从柴胡中分离到的三萜皂苷类天然产物，具有抗炎，抗菌，抗肿瘤，抗过敏作用。它抑制 selectin，STAT3和 NF-kB 的活性，活化estrogen receptor-β。
T5S1607	Morusin Mulberrochromene,桑辛素	NF-κB; Antibacterial; STAT	JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells
	Morusin (Mulberrochromene) 是从M. australis 分离的去乙烯基化黄酮，可抑制NF-κB 和STAT3的活性，具有抗菌、抗肿瘤、抗氧化等各种生物活性。
TJS1779	Protosappanin A 原苏木素A,PTA	NADPH-oxidase; IL Receptor; IκB/IKK; TNF; NF-κB; TLR; ROS; COX; HIV Protease; JAK; NO Synthase; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome; Stem Cells
	Protosappanin A (PTA) 是从苏木中分离得到的免疫抑制成分和主要联苯化合物，通过下调 JAK2和 STAT3的磷酸化，抑制 JAK2/STAT3依赖的炎症通路。
T4S0145	Corylifol A Corylinin,补骨脂异黄酮A	hCE; STAT; UGT	JAK/STAT signaling; Metabolism; Stem Cells
	Corylifol A (Corylinin) 是补骨脂中的一种天然产物，可抑制IL-6 诱导的STAT3激活和磷酸化，IC50值为0.81 μM。
T2787	Picroside I 6'-Cinnamoylcatalpol,胡黄连苦苷I	MMP; STAT	JAK/STAT signaling; Proteases/Proteasome; Stem Cells
	Picroside I (6'-Cinnamoylcatalpol) 是胡黄连的一种天然产物，是有肝脏保护作用的代谢成分，可用于哮喘研究，有减轻炎症作用，还下调 pSTAT6 和 GATA3 表达。
TN2269	Tetramethylcurcumin	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	Tetramethylcurcumin 是一种新型姜黄素类似物，是一种有效的 STAT3 磷酸化、DNA 结合活性和体外反式激活抑制剂。它具有抗炎和抗癌作用。
T0433	Artesunate WR-256283,青蒿琥酯	Virus Protease; Ferroptosis; STAT; Parasite	Apoptosis; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Artesunate (WR-256283) 是治疗疟疾的青蒿素组药物的一部分。它是青蒿素的半合成衍生物，具有水溶性。
T2814	Cryptotanshinone 隐丹参酮,Cryptotanshinon,Tanshinone c,隐丹参醌	STAT; Autophagy	Autophagy; JAK/STAT signaling; Stem Cells
	Cryptotanshinone (Tanshinone c) 属于天然产物，提取自丹参，可以抑制 STAT3 (IC50=4.6 μM)。Cryptotanshinone 具有抗肿瘤活性。
TN1413	Atranorin 荔枝素，巴美灵,荔枝素	Endogenous Metabolite; NO Synthase; Ras	GPCR/G Protein; Immunology/Inflammation; MAPK; Metabolism
	Atranorin 是地衣的次生代谢产物，具有显着的抗伤害、抗炎和氧化还原活性，对 H(2)O(2) 诱导的氧化应激下的细胞具有细胞保护作用。
T6995	Ochromycinone STA 21,STA21,STA-21	Antibacterial; STAT	JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Ochromycinone (STA 21) 是一种天然抗生素，也是一种 STAT3抑制剂。它可抑制 STAT3DNA 结合活性，STAT3二聚化。它具有抗癌和抗菌活性。
T6S1373	Casticin Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin,蔓荆子黄素	STAT	JAK/STAT signaling; Stem Cells
	Casticin (Vitexicarpin) 是从蔓荆子中得到的一种甲氧基黄酮，可抑制STAT3的活化，具有抗有丝分裂和抗炎活性。
T6S1966	Curculigoside Curculigoside A,仙茅苷	Antioxidant; NF-κB; JAK; STAT	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; oxidation-reduction; Stem Cells
	Curculigoside (Curculigoside A) 是仙茅中的主要皂苷，具有显著的抗氧化、抗骨质疏松、抗抑郁和神经保护作用。它通过调节JAK/STAT/NF-κB 信号传导途径，具有抗关节炎作用。
T3380	Homoharringtonine Myelostat,Ceflatonin,高三尖杉酯碱,HHT,Omacetaxine mepesuccinate	STAT	JAK/STAT signaling; Stem Cells
	Homoharringtonine (HHT) 属于生物碱类天然产物，可以抑制蛋白质的翻译，具有细胞毒性。Homoharringtonine 作用于肿瘤细胞的核糖体，抑制蛋白质翻译的延伸步骤，从而抑制蛋白质合成，具有抗肿瘤活性。
TN1673	Garcinone C 伽升沃 C,伽升沃C	ATM/ATR; CDK; STAT; AChR; Antifection	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; JAK/STAT signaling; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling; Stem Cells
	Garcinone C 是一种从 Garcinia oblongifolia Champ 中提取的黄酮衍生物，具有抗炎、收敛和促进肉芽的活性。 Garcinone C 是一种 AChE 抑制剂，对某些癌症具有潜在的细胞毒性作用。
T5S0167	Atractylenolide I 白术内酯 I,白术内酯I；苍术内酯I	IL Receptor; TNF; TLR; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Atractylenolide I 是从白术根中得到的一种倍半萜烯，具有神经保护、抗过敏、抗炎和抗癌等多种生物活性。它是一种TLR4拮抗剂，在 A375 细胞中，能够降低JAK2和STAT3的磷酸化水平。
TN1405	Arnicolide D 山金车内酯 D,山金车内酯D	Akt; Caspase; PI3K; STAT; mTOR	Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Arnicolide D 是从石胡荽中分离出的一种倍半萜内酯，以浓度和时间依赖性方式抑制鼻咽癌细胞活力。它调节细胞周期，激活 caspase 信号通路并抑制 PI3K/AKT/mTOR 和 STAT3 信号通路。
T5S0761	Nitidine chloride	Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite	Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的，具有抗疟疾活性。它通过多个靶点通路，起抗癌作用，抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。
T2789	Scutellarin 黄岑素,野黄芩苷,Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide	Akt; HIV Protease; STAT	Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Scutellarin (Scutellarein-7-glucuronide) 是从黄芩中分离的黄酮，可抑制破骨细胞中 RANKL 介导的 MAPK 和 NF-κB 信号通路，并下调 HCC 细胞中的 STAT3/Girdin/Akt 信号通路。
T73070	STAT3-IN-14	Others	Others
	STAT3-IN-14是一种STAT3抑制剂，具有STAT3磷酸化抑制活性，可直接与 STAT3的铰链区结合。
T2763	Panaxadiol 人参二醇,20(R)-Panaxadiol	Others; HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism; Others
	Panaxadiol (20(R)-Panaxadiol) 是从人参根中获得，具有神经保护和抗肿瘤作用，能够抑制程序性细胞死亡配体-1(PD-L1)的表达和肿瘤增殖。
T2896	Alantolactone 土木香内酯,helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,土木香脑,Inula camphor	Apoptosis; STAT; TGF-beta/Smad	Apoptosis; JAK/STAT signaling; Stem Cells
	Alantolactone (Inula camphor) 是一种STAT3的选择性抑制剂，可诱导癌症相关的凋亡，具有抗肿瘤活性。
T5668	Triacetylresveratrol 乙酰化白藜芦醇,三乙酰基白藜芦醇,Acetyl-trans-resveratrol	BCL; NF-κB; STAT	Apoptosis; JAK/STAT signaling; NF-κB; Stem Cells
	Triacetylresveratrol (Acetyl-trans-resveratrol) 是 Resveratrol 的乙酰化类似物，可降低 STAT3和 NF-κB 磷酸化，具有抗癌作用。
TQ0196	Cucurbitacin I NSC-521777,JSI-124,Elatericin B,葫芦素 I	JAK; STAT	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	Cucurbitacin I (JSI-124) 是从曲莲中提取的一种天然产物，是 JAK2/STAT3选择性抑制剂，有抗肿瘤活性。
T3138	Astaxanthin β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin,虾青素	Reactive Oxygen Species; PPAR	DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB
	Astaxanthin (trans-Astaxanthin) 是可从雨生红球藻等多种海洋生物中提取得到的红色类胡萝卜素，是过氧化物酶体增殖物活化受体γ 的调节剂，具有抗增殖、神经保护作用和抗炎活性。它是一种抗氧化剂，有用于癌症和心血管疾病的研究潜力，作为颜色添加剂用于动物食品中。
TN1631	Eupalinolide K [3AR-[3AR,4R(E),6E,9S,10E,11AR]]-4-羟基-2-甲基-2-丁烯酸 2,3,3A,4,5,8,9,11A-八氢-9-羟基-6,10-二甲基-3-亚甲基-2-氧代环癸五烯并[B]呋喃-4-基酯,野马追内酯 K,野马追内酯K	STAT	JAK/STAT signaling; Stem Cells
	Eupalinolide K 是来自野马追的一种倍半萜内酯，是 STAT3抑制剂，可作为迈克尔反应受体。
T5756	Hastatoside 戟叶马鞭草苷	Others	Others
	Hastatoside 是一种环烯醚萜苷，分离自 Verbena officinalis 中，具有促进睡眠的效果。
T1257	Bestatin Ubenimex,乌苯美司	Others; Aminopeptidase; Antibacterial; Antibiotic; LTR	Immunology/Inflammation; Metabolism; Microbiology/Virology; Others
	Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂，可用于癌症研究。
T10939L	L-Cystathionine L-胱硫醚,Cystathionine,ZINC1532680,L-(+)-Cystathionine,Cystathionine, L-	Apoptosis; Endogenous Metabolite	Apoptosis; Metabolism
	L-Cystathionine (Cystathionine, L-) 是一种与含硫氨基酸的代谢条件有关的关键非蛋白质氨基酸。L-Cystathionine 可用于有关心血管保护的研究。
T1207	Lovastatin MK-803,洛伐他汀,Mevinolin	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Lovastatin (MK-803) 是一种 HMG-CoA 还原酶抑制剂，用于降低胆固醇。
T0672	Pravastatin sodium CS-514 Sodium,普伐他汀钠,CS-514 (sodium)	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Pravastatin sodium (CS-514 (sodium)) 是一种 HMG-CoA 还原酶抑制剂，抑制甾醇合成，IC50 为 5.6 μM。
T1678	Nystatin Stamycin,Fungicidin,制霉菌素,Nystavescent	Apoptosis; Antibiotic; Antifungal	Apoptosis; Microbiology/Virology
	Nystatin (Fungicidin) 属于多烯类抗真菌抗生素，对酵母和支原体有效，具有口服活性。Nystatin 可以用于治疗皮肤和口咽念珠菌感染。
TQ0198	Phorbol 12-myristate 13-acetate 佛波醇12-十四酸酯13-乙酸酯,PMA	NF-κB; S1P Receptor; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; GPCR/G Protein; NF-κB
	Phorbol 12-myristate 13-acetate (PMA) 属于佛波酯类天然产物，是一种 PKC、SphK、NF-κB 的激活剂。Phorbol 12-myristate 13-acetate 可诱导 THP1 细胞分化。
T8040	Cholesterol myristate 胆甾烯基豆蔻酸酯,Cholesteryl myristate,胆固醇肉豆蔻酸,Cholesteryl tetradecanoate	Others; Potassium Channel; GABA Receptor; Endogenous Metabolite; AChR	Membrane transporter/Ion channel; Metabolism; Neuroscience; Others
	Cholesterol myristate (Cholesteryl myristate) 是粗吻海龙中的一种类固醇，可与多种离子通道结合，例如nAChR、GABAA 受体和内向整流钾离子通道。
T3529	Bestatin hydrochloride 盐酸乌苯美司,Ubenimex hydrochloride,苯丁抑制素	Integrin; Aminopeptidase; Antibacterial; Antibiotic	Cytoskeletal Signaling; Metabolism; Microbiology/Virology
	Bestatin hydrochloride (Ubenimex hydrochloride) 是CD13(Aminopeptidase N)/APN 和leukotriene A4 hydrolase 抑制剂，可研究癌症。
T6270	Trichostatin A 曲古柳菌素A,曲古抑菌素A,TSA	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Trichostatin A (TSA) 属于二烯异羟肟酸类的天然衍生物。Trichostatin A 是一种组蛋白去乙酰化酶抑制剂 (IC50=1.8 nM)，具有可逆性和特异性。Trichostatin A 导致核心组蛋白过度乙酰化，从而调节染色质结构。
TN6994	Ethyl Myristate Ethyl tetradecanoate	Others	Others
	Ethyl Myristate (Ethyl tetradecanoate) 是一种可从啤酒花中提取的化合物，具有保湿作用，常用于护肤品行业。
T6212	Combretastatin A4 CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09	Microtubule Associated	Cytoskeletal Signaling
	Combretastatin A4 (CA4) 是一种微管靶向剂，可结合 β-tubulin，Kd 值为 0.4 μM。
T0683	Mevastatin Compactin,ML236B,美伐他汀	Apoptosis; Antibacterial; Antibiotic; HMG-CoA Reductase; Autophagy; Lipid	Apoptosis; Autophagy; Metabolism; Microbiology/Virology
	Mevastatin (ML236B) 是他汀类 HMG-CoA 还原酶抑制剂。它是一种降脂药，可诱导细胞凋亡，将癌细胞阻滞在 G0/G1期。它还可增加内皮型一氧化氮合酶的 mRNA 和蛋白质水平。它有抗肿瘤活性，用于心血管疾病的研究。
T20005	Isopropyl myristate IPM,Isomyst,HSDB 626,肉豆蔻酸异丙酯,FEMA No. 3556,十四酸异丙酯,NSC 406280,Stepan D-50	Others	Others
	Isopropyl myristate (IPM) 是异丙醇和肉豆蔻酸的酯。它是一种可用于化妆品和外用药物制剂中的极性润肤剂。
TN6901	Methyl myristate 肉豆蔻酸甲酯,methyl tetradecanoate	Others	Others
	Methyl myristate (methyl tetradecanoate) 是一种肉豆蔻酸经酯化反应得到的饱和脂肪酸甲酯。对 B16F10 黑色素瘤具有显著的诱导作用。
TP1180	Dolastatin 10 尾海兔素10,NSC 376128,DLS 10	Microtubule Associated; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling
	Dolastatin 10 (DLS 10) 是一种多肽，可以抑制微管蛋白聚合，显示除抗有丝分裂的活性。
T0687	Simvastatin 辛伐他汀,MK-0733,MK 733	Apoptosis; Mitophagy; Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Simvastatin (MK 733) 是一种 HMG-CoA 还原酶抑制剂 (Ki=0.2 nM)，具有口服活性。Simvastatin 具有降血脂活性，可以抑制肝脏产生胆固醇，还可以用于预防心血管疾病。
T12039	Miglustat N-Butyldeoxynojirimycin,OGT918,美格鲁特,NB-DNJ,N-丙基脱氧野尻霉素	Others	Others
	Miglustat (NB-DNJ) 是一种葡萄糖神经酰胺合成酶抑制剂，可用于I 型戈谢病。
TN4546	Methyl isocostate	Others	Others
	Methyl isocostate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4546，CAS号为 132342-55-3。
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天然产物

Cat.No: TN2346

Target: ERK, AMPK, STAT

Cat.No: T4672

Target: Apoptosis, Anti-infection, JAK, STAT, Autophagy

Cat.No: T2867

Synonym: 山药,Nitogenin

Target: STAT

Cat.No: TN6739

Synonym: 6-Methoxyldihydrochelerythrine

Target: IL Receptor, STAT

Cat.No: T6S0071

Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1

Cat.No: TN1674

Synonym: 伽升沃 D

Target: Reactive Oxygen Species, Nrf2, STAT

Cat.No: T3913

Target: Estrogen Receptor/ERR, NF-κB, Antibacterial, STAT

Cat.No: T5S1607

Synonym: Mulberrochromene,桑辛素

Target: NF-κB, Antibacterial, STAT

Protosappanin A

Cat.No: TJS1779

Synonym: 原苏木素A,PTA

Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT

Cat.No: T4S0145

Synonym: Corylinin,补骨脂异黄酮A

Target: hCE, STAT, UGT

Cat.No: T2787

Synonym: 6'-Cinnamoylcatalpol,胡黄连苦苷I

Target: MMP, STAT

Tetramethylcurcumin

Cat.No: TN2269

Target: Apoptosis, STAT

Cat.No: T0433

Synonym: WR-256283,青蒿琥酯

Target: Virus Protease, Ferroptosis, STAT, Parasite

Cryptotanshinone

Cat.No: T2814

Synonym: 隐丹参酮,Cryptotanshinon,Tanshinone c,隐丹参醌

Target: STAT, Autophagy

Cat.No: TN1413

Synonym: 荔枝素，巴美灵,荔枝素

Target: Endogenous Metabolite, NO Synthase, Ras

Cat.No: T6995

Synonym: STA 21,STA21,STA-21

Target: Antibacterial, STAT

Cat.No: T6S1373

Synonym: Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin,蔓荆子黄素

Target: STAT

Cat.No: T6S1966

Synonym: Curculigoside A,仙茅苷

Target: Antioxidant, NF-κB, JAK, STAT

Homoharringtonine

Cat.No: T3380

Synonym: Myelostat,Ceflatonin,高三尖杉酯碱,HHT,Omacetaxine mepesuccinate

Target: STAT

Cat.No: TN1673

Synonym: 伽升沃 C,伽升沃C

Target: ATM/ATR, CDK, STAT, AChR, Antifection

Atractylenolide I

Cat.No: T5S0167

Synonym: 白术内酯 I,白术内酯I；苍术内酯I

Target: IL Receptor, TNF, TLR, JAK, STAT

Cat.No: TN1405

Synonym: 山金车内酯 D,山金车内酯D

Target: Akt, Caspase, PI3K, STAT, mTOR

Nitidine chloride

Cat.No: T5S0761

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

Cat.No: T2789

Synonym: 黄岑素,野黄芩苷,Breviscapin,Breviscapinun,Breviscapine,Scutellarein-7-glucuronide

Target: Akt, HIV Protease, STAT

Cat.No: T73070

Target: Others

Cat.No: T2763

Synonym: 人参二醇,20(R)-Panaxadiol

Target: Others, HIF/HIF Prolyl-Hydroxylase

Cat.No: T2896

Synonym: 土木香内酯,helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,土木香脑,Inula camphor

Target: Apoptosis, STAT, TGF-beta/Smad

Triacetylresveratrol

Cat.No: T5668

Synonym: 乙酰化白藜芦醇,三乙酰基白藜芦醇,Acetyl-trans-resveratrol

Target: BCL, NF-κB, STAT

Cat.No: TQ0196

Synonym: NSC-521777,JSI-124,Elatericin B,葫芦素 I

Target: JAK, STAT

Cat.No: T3138

Synonym: β-Carotene-4,4'-dione,Ovoester,AstaXin,AstaREAL,trans-Astaxanthin,虾青素

Target: Reactive Oxygen Species, PPAR

Cat.No: TN1631

Synonym: [3AR-[3AR*,4R*(E),6E,9S*,10E,11AR*]]-4-羟基-2-甲基-2-丁烯酸 2,3,3A,4,5,8,9,11A-八氢-9-羟基-6,10-二甲基-3-亚甲基-2-氧代环癸五烯并[B]呋喃-4-基酯,野马追内酯 K,野马追内酯K

Target: STAT

Cat.No: T5756

Synonym: 戟叶马鞭草苷

Target: Others

Cat.No: T1257

Synonym: Ubenimex,乌苯美司

Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR

L-Cystathionine

Cat.No: T10939L

Synonym: L-胱硫醚,Cystathionine,ZINC1532680,L-(+)-Cystathionine,Cystathionine, L-

Target: Apoptosis, Endogenous Metabolite

Cat.No: T1207

Synonym: MK-803,洛伐他汀,Mevinolin

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Pravastatin sodium

Cat.No: T0672

Synonym: CS-514 Sodium,普伐他汀钠,CS-514 (sodium)

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T1678

Synonym: Stamycin,Fungicidin,制霉菌素,Nystavescent

Target: Apoptosis, Antibiotic, Antifungal

Phorbol 12-myristate 13-acetate

Cat.No: TQ0198

Synonym: 佛波醇12-十四酸酯13-乙酸酯,PMA

Target: NF-κB, S1P Receptor, PKC

Cholesterol myristate

Cat.No: T8040

Synonym: 胆甾烯基豆蔻酸酯,Cholesteryl myristate,胆固醇肉豆蔻酸,Cholesteryl tetradecanoate

Target: Others, Potassium Channel, GABA Receptor, Endogenous Metabolite, AChR

Bestatin hydrochloride

Cat.No: T3529

Synonym: 盐酸乌苯美司,Ubenimex hydrochloride,苯丁抑制素

Target: Integrin, Aminopeptidase, Antibacterial, Antibiotic

Cat.No: T6270

Synonym: 曲古柳菌素A,曲古抑菌素A,TSA

Target: HDAC

Ethyl Myristate

Cat.No: TN6994

Synonym: Ethyl tetradecanoate

Target: Others

Combretastatin A4

Cat.No: T6212

Synonym: CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09

Target: Microtubule Associated

Cat.No: T0683

Synonym: Compactin,ML236B,美伐他汀

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

Isopropyl myristate

Cat.No: T20005

Synonym: IPM,Isomyst,HSDB 626,肉豆蔻酸异丙酯,FEMA No. 3556,十四酸异丙酯,NSC 406280,Stepan D-50

Target: Others

Methyl myristate

Cat.No: TN6901

Synonym: 肉豆蔻酸甲酯,methyl tetradecanoate

Target: Others

Cat.No: TP1180

Synonym: 尾海兔素10,NSC 376128,DLS 10

Target: Microtubule Associated, ADC Cytotoxin

Cat.No: T0687

Synonym: 辛伐他汀,MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T12039

Synonym: N-Butyldeoxynojirimycin,OGT918,美格鲁特,NB-DNJ,N-丙基脱氧野尻霉素

Target: Others

Methyl isocostate

Cat.No: TN4546

Target: Others

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02603	STAT6 Protein, Human, Recombinant (His) STAT6C,IL-4-STAT,STAT6B,signal tr...	Human	Baculovirus Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators...
TMPH-02919	SOCS1 Protein, Mouse, Recombinant (His & Myc) STAT-induced STAT inhibitor 1,Suppressor o...	Mouse	E. coli
	SOCS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.7 kDa and the accession number is O35716.
TMPH-02156	SOCS1 Protein, Human, Recombinant (His) SOCS1,STAT-induced STAT inhibitor 1,JAK-bi...	Human	P. pastoris (Yeast)
	SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Through binding to JAKs and IFNGR1, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity. Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron surviv...
TMPH-02155	SOCS1 Protein, Human, Recombinant (E. coli, His) Tec-interacting protein 3,JAK-binding protein,Suppressor of ...	Human	E. coli
	SOCS1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.6 kDa and the accession number is O15524.
TMPY-06624	STAT3 Protein, Human, Recombinant (His) ADMIO,signal transducer and activator of transcription 3 (ac...	Human	E. coli
	STAT3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 65.31 kDa and the accession number is P40763-1.
TMPY-02240	STAT1 Protein, Human, Recombinant (His & GST) IMD31A,IMD31B,IMD31C,STAT91,CANDF7,signal transduce...	Human	Baculovirus Insect Cells
	STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands, including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. It is a signal transducer and transcription activator that mediates cellular responses to interferons (IFNs),...
TMPJ-00961	STAT1 Protein, Human, Recombinant Transcription Factor ISGF-3 Components p91/p84,STAT...	Human	E. coli
	Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellul...
TMPY-02581	STAT4 Protein, Human, Recombinant (His) signal transducer and activator of transcription 4,SLEB11	Human	Baculovirus Insect Cells
	High expression of STAT4 in gastric cancer predicted a better clinical outcome. STAT4 might be a useful biomarker to identify patients at high risk of recurrence after gastrectomy. Genetic variants in the transcription factor STAT4 are associated with increased susceptibility to systemic lupus erythematosus (SLE) and a more severe disease phenotype.
TMPU-00003	STAT2 Protein, Human, Recombinant (His)	Human	E. coli
	Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of...
TMPU-00004	STAT5A Protein, Human, Recombinant (His) MGF,Signal transducer and activator of transcription 5A	Human	E. coli
	Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate cancer. Until recently, the unique characteristics and function of STAT5a in these cancers have not been delineated from STAT5b, and more research into their differential behavior is warranted. Because of its integral role in immune cell development, STAT5a may contribute to tumor de...
TMPJ-01003	STAT5B Protein, Human, Recombinant (His) Signal Transducer and Activator of Transcription 5B,STAT...	Human	E. coli
	Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adul...
TMPY-00767	Cystatin C Protein, Human, Recombinant (His) ARMD11,cystatin C	Human	HEK293 Cells
	Cystatin C Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is A0A0K0K1J1.
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) Oncostatin-M,OSM	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac...
TMPY-02359	Follistatin Protein, Mouse, Recombinant (His) FS,follistatin,AL033346	Mouse	HEK293 Cells
	Follistatin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.1 kDa and the accession number is P47931.
TMPY-02212	Follistatin Protein, Human, Recombinant (hFc) follistatin,FS	Human	HEK293 Cells
	Follistatin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.7 kDa and the accession number is NP_037541.1.
TMPY-04062	Oncostatin M/OSM Protein, Mouse, Recombinant oncostatin M,OncoM	Mouse	E. coli
	Oncostatin M/OSM Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 20.7 kDa and the accession number is P53347.
TMPY-02672	Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) 5'-NT,9.104100899-104272570.1,Ppal,A030005E02Rik,PAP,Lap,aci...	Mouse	HEK293 Cells
	Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q8CE08-1.
TMPY-02077	Cystatin A Protein, Human, Recombinant (His) STFA,STF1,cystatin A,AREI	Human	E. coli
	Cystatin-A, also known as Cystatin-AS, Stefin-A and CSTA, is a cytoplasm protein which belongs to thecystatin family. Cystatin-A / CSTA is a cysteine proteinase inhibitor with a molecular mass of 11 kDa, and is located mainly in the keratohyaline granules of the stratum granulosum and the cornified envelope of the stratum corneum in the epidermis. The cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. Cystatins are physiological inhibitors of cystein...
TMPY-03971	Statherin Protein, Human, Recombinant (mFc) statherin,STATH,STR	Human	HEK293 Cells
	Statherin, also known as STATH, belongs to the histatin/statherin family. Statherin may play an important role in the maintenance of oral health. It prevents calcium phospate precipitation in saliva, so maintaining a high calcium level in saliva and preventing teeth from dissolving. Statherin also inhibits spontaneous precipitation of calcium phosphate salts. Thus, statherin and PRPs may prevent build-up of harmful deposits in the salivary glands and on the tooth surfaces. Statherin is a highly ...
TMPY-02856	Cystatin F/CST7 Protein, Mouse, Recombinant (hFc) Cmap,cystatin F (leukocystatin)	Mouse	HEK293 Cells
	Cystatin F/CST7 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.4 kDa and the accession number is O89098.
TMPY-00769	Cystatin F/CST7 Protein, Human, Recombinant (hFc) cystatin F (leukocystatin),CMAP	Human	HEK293 Cells
	Cystatin F/CST7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is O76096.
TMPY-02090	Cystatin B Protein, Human, Recombinant (His) PME,EPM1A,STFB,ULD,cystatin B (stefin B),EPM1,CST6	Human	E. coli
	Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the prot...
TMPY-02256	Follistatin Protein, Human, Recombinant (His) FS,follistatin	Human	HEK293 Cells
	Follistatin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33 kDa and the accession number is P19883-2.
TMPY-00729	Cystatin D Protein, Human, Recombinant (His) CST5,MGC71922,cystatin D	Human	HEK293 Cells
	Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. As a member of type 2 cystatin, cystatin D is a single-domain protein and also has cysteine residues that form disulfide bridges. In contrast with the wider distribution of all the other family 2 cystatins, cystatin D is tissue-restricte...
TMPY-02155	Prostatic Acid Phosphatase Protein, Human, Recombinant (His) 5'-NT,acid phosphatase, prostate,PAP,ACP-3,ACP3	Human	HEK293 Cells
	Prostatic Acid Phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P15309-2.
TMPY-01645	Cystatin SA Protein, Human, Recombinant (His) CST2,MGC71924,cystatin SA	Human	HEK293 Cells
	Cystatin-SA, also known as Cystatin-2, Cystatin-S5 and CST2, is a secreted protein which belongs to thecystatin family. Cystatin-2 / CST2 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). It is also expressed in submandibular gland and parotid gland. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never ...
TMPJ-01174	Cystatin B Protein, Mouse, Recombinant (His) PME,CST6cystatin B (liver thiol proteinase inhibito...	Mouse	E. coli
	Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases of the papain family such as cathepsins B, H and L. Defects in Cystatin-B / CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) which is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures.
TMPK-00146	Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated OSM,MGC20461,Oncostatin M	Human	HEK293 Cells
	Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.1 kDa and the accession number is P13725.
TMPH-03639	COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc) Cytochrome c oxidase subunit VIIa-H,COX7A1,Cytochrome c oxid...	Trachypithecus cristatus	HEK293 Cells
	N/A. COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 31.9 kDa and the accession number is Q9N234.
TMPH-02445	Oncostatin M/OSM Protein, Rhesus macaque, Recombinant (His) OSM	Rhesus	Baculovirus Insect Cells
	Oncostatin M/OSM Protein, Rhesus macaque, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 28.8 kDa and the accession number is F7GF43.
TMPH-03375	Stathmin-2 Protein, Rat, Recombinant (His) Superior cervical ganglion-10 protein,Stmn2,Stathmi...	Rat	E. coli
	Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone. Stathmin-2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.7 kDa and the accession number is P21818.
TMPH-02910	Somatostatin Protein, Mouse, Recombinant (His & KSI) Sst,Somatostatin	Mouse	E. coli
	Somatostatin Protein, Mouse, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 18.5 kDa and the accession number is P60041.
TMPH-02138	Stathmin-4 Protein, Human, Recombinant (GST) STMN4,Stathmin-4,Stathmin-like protein B3	Human	E. coli
	Exhibits microtubule-destabilizing activity. Stathmin-4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 52.4 kDa and the accession number is Q9H169.
TMPY-03368	Follistatin Protein, Mouse, Recombinant (hFc) follistatin,FS,AL033346	Mouse	CHO Cells
	Follistatin Protein, Mouse, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 58.4 kDa and the accession number is P47931.
TMPY-02627	Oncostatin M/OSM Protein, Mouse, Recombinant (His) OncoM,oncostatin M	Mouse	HEK293 Cells
	Oncostatin M/OSM Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P53347.
TMPJ-00227	Follistatin 288 Protein, Human, Recombinant (His) FSActivin-binding protein,Follistatin,follistat...	Human	HEK293 Cells
	Follistatin 288 is a secreted glycoprotein that was first identified as a follicle-stimulating hormone inhibiting substance in ovarian follicular fluid . Human follistatin 288 cDNA encodes a 317 amino acid (aa) protein with a 29 aa signal sequence, and a 288 aa mature region. Follistatin shows the highest affinity for activins due to its extended configuration. Genetic deletion of follistatin in mice, or expression of only the Follistatin form, is perinatally lethal due to defects of lung, skin ...
TMPK-00145	Oncostatin M/OSM Protein, Human, Recombinant (His & Avi) Oncostatin M,OSM,MGC20461	Human	HEK293 Cells
	Oncostatin M/OSM Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.1 kDa and the accession number is P13725.
TMPH-02763	Lithostathine-1/Reg1 Protein, Mouse, Recombinant (His & SUMO) Reg1,Pancreatic thread protein 1,Islet of Langerhans regener...	Mouse	E. coli
	Lithostathine-1/Reg1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-01370	Cystatin C Protein, Mouse, Recombinant (His) cystatin C,CysC	Mouse	HEK293 Cells
	Cystatin C Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P21460.
TMPY-02364	Oncostatin M/OSM Protein, Human, Recombinant (His) oncostatin M	Human	HEK293 Cells
	Oncostatin M/OSM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.6 kDa and the accession number is P13725.
TMPY-02056	Cystatin C Protein, Rat, Recombinant (His) cystatin C	Rat	HEK293 Cells
	Cystatin C Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.7 kDa and the accession number is P14841-1.
TMPY-01644	Cystatin S Protein, Human, Recombinant (His) MGC71923,cystatin S,CST4	Human	HEK293 Cells
	Cystatin-S, also known as Cystatin-4, Salivary acidic protein 1, Cystatin-SA-III and CST4, is a secreted protein which belongs to thecystatin family. Cystatin-4 / CST4 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). It is also expressed in saliva, tears, urine and seminal fluid. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while oth...
TMPY-00283	Oncostatin M/OSM Protein, Human, Recombinant oncostatin M	Human	HEK293 Cells
	Oncostatin M/OSM Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.16 kDa and the accession number is P13725.
TMPK-00576	Oncostatin M/OSM Protein, Canine, Recombinant (His) Oncostatin M,OSM,MGC20461	Canine	HEK293 Cells
	Oncostatin M/OSM Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.65 kDa and the accession number is A0A8I3Q5M1.
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) Platelet aggregation activation inhibitor,Disintegrin colomb...	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Also inhibits T24 and SK-Mel-28 cell adhesion to fibronectin with IC(50) of 4.4 uM and 33 nM, respectively. Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted...
TMPH-03419	Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP6 Protein (His) Intermediate capsid protein VP6	RV-A	E. coli
	Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP6 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50.9 kDa and the accession number is P03530.
TMPH-03062	Norovirus (strain Human/NoV/United States/Norwalk/1968/GI) VP1 Protein (Flag & Myc) p59,Capsid protein VP1	Norwalk virus	HEK293 Cells
	Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding histo-blood group antigens present on gastroduodenal epithelial cells.; Soluble capsid protein may play a role in viral immunoevasion.
TMPY-01368	Cystatin F/CST7 Protein, Human, Recombinant (His) CMAP,cystatin F (leukocystatin)	Human	HEK293 Cells
	Cystatin F/CST7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.1 kDa and the accession number is O76096.
TMPY-00640	Cystatin C Protein, Human, Recombinant ARMD11,cystatin C	Human	HEK293 Cells
	Cystatin C Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.3 kDa and the accession number is AAA52164.1.
TMPY-02070	Cystatin SN Protein, Human, Recombinant (His) CST1,cystatin SN	Human	HEK293 Cells
	Cystatin-SN, also known as Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1 and CST1, is a secreted protein which belongs to thecystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. Cystatin-SN / CST1 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Cy...
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重组蛋白

STAT6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02603

Species: Human

Expression System: Baculovirus Insect Cells

SOCS1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02919

Species: Mouse

Expression System: E. coli

SOCS1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02156

Species: Human

Expression System: P. pastoris (Yeast)

SOCS1 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02155

Species: Human

Expression System: E. coli

STAT3 Protein, Human, Recombinant (His)

Cat.No: TMPY-06624

Species: Human

Expression System: E. coli

STAT1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02240

Species: Human

Expression System: Baculovirus Insect Cells

STAT1 Protein, Human, Recombinant

Cat.No: TMPJ-00961

Species: Human

Expression System: E. coli

STAT4 Protein, Human, Recombinant (His)

Cat.No: TMPY-02581

Species: Human

Expression System: Baculovirus Insect Cells

STAT2 Protein, Human, Recombinant (His)

Cat.No: TMPU-00003

Species: Human

Expression System: E. coli

STAT5A Protein, Human, Recombinant (His)

Cat.No: TMPU-00004

Species: Human

Expression System: E. coli

STAT5B Protein, Human, Recombinant (His)

Cat.No: TMPJ-01003

Species: Human

Expression System: E. coli

Cystatin C Protein, Human, Recombinant (His)

Cat.No: TMPY-00767

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPJ-01467

Species: Human

Expression System: E. coli

Follistatin Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02359

Species: Mouse

Expression System: HEK293 Cells

Follistatin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02212

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Mouse, Recombinant

Cat.No: TMPY-04062

Species: Mouse

Expression System: E. coli

Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02672

Species: Mouse

Expression System: HEK293 Cells

Cystatin A Protein, Human, Recombinant (His)

Cat.No: TMPY-02077

Species: Human

Expression System: E. coli

Statherin Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03971

Species: Human

Expression System: HEK293 Cells

Cystatin F/CST7 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02856

Species: Mouse

Expression System: HEK293 Cells

Cystatin F/CST7 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00769

Species: Human

Expression System: HEK293 Cells

Cystatin B Protein, Human, Recombinant (His)

Cat.No: TMPY-02090

Species: Human

Expression System: E. coli

Follistatin Protein, Human, Recombinant (His)

Cat.No: TMPY-02256

Species: Human

Expression System: HEK293 Cells

Cystatin D Protein, Human, Recombinant (His)

Cat.No: TMPY-00729

Species: Human

Expression System: HEK293 Cells

Prostatic Acid Phosphatase Protein, Human, Recombinant (His)

Cat.No: TMPY-02155

Species: Human

Expression System: HEK293 Cells

Cystatin SA Protein, Human, Recombinant (His)

Cat.No: TMPY-01645

Species: Human

Expression System: HEK293 Cells

Cystatin B Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01174

Species: Mouse

Expression System: E. coli

Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00146

Species: Human

Expression System: HEK293 Cells

COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc)

Cat.No: TMPH-03639

Species: Trachypithecus cristatus

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPH-02445

Species: Rhesus

Expression System: Baculovirus Insect Cells

Stathmin-2 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03375

Species: Rat

Expression System: E. coli

Somatostatin Protein, Mouse, Recombinant (His & KSI)

Cat.No: TMPH-02910

Species: Mouse

Expression System: E. coli

Stathmin-4 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02138

Species: Human

Expression System: E. coli

Follistatin Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03368

Species: Mouse

Expression System: CHO Cells

Oncostatin M/OSM Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02627

Species: Mouse

Expression System: HEK293 Cells

Follistatin 288 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00227

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00145

Species: Human

Expression System: HEK293 Cells

Lithostathine-1/Reg1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02763

Species: Mouse

Expression System: E. coli

Cystatin C Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01370

Species: Mouse

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Human, Recombinant (His)

Cat.No: TMPY-02364

Species: Human

Expression System: HEK293 Cells

Cystatin C Protein, Rat, Recombinant (His)

Cat.No: TMPY-02056

Species: Rat

Expression System: HEK293 Cells

Cystatin S Protein, Human, Recombinant (His)

Cat.No: TMPY-01644

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Human, Recombinant

Cat.No: TMPY-00283

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Canine, Recombinant (His)

Cat.No: TMPK-00576

Species: Canine

Expression System: HEK293 Cells

Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)

Cat.No: TMPH-00213

Species: Bothrops atrox

Expression System: E. coli

Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) VP6 Protein (His)

Cat.No: TMPH-03419

Species: RV-A

Expression System: E. coli

Norovirus (strain Human/NoV/United States/Norwalk/1968/GI) VP1 Protein (Flag & Myc)

Cat.No: TMPH-03062

Species: Norwalk virus

Expression System: HEK293 Cells

Cystatin F/CST7 Protein, Human, Recombinant (His)

Cat.No: TMPY-01368

Species: Human

Expression System: HEK293 Cells

Cystatin C Protein, Human, Recombinant

Cat.No: TMPY-00640

Species: Human

Expression System: HEK293 Cells

Cystatin SN Protein, Human, Recombinant (His)

Cat.No: TMPY-02070

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T70882	Orlistat-d3
	Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...
TMIH-0242	Fluvastatin-d6 Sodium Salt
	Fluvastatin-d6 Sodium Salt 是 Fluvastatin Sodium Salt 的氘代化合物。Fluvastatin Sodium Salt 的 CAS 号为 93957-55-2。Fluvastatin sodium salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂，IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激，是一种常用的降胆固醇剂。
T12488	Pitavastatin D4 NK-104 D4	Others	Others
	Pitavastatin D4 is deuterium labeled Pitavastatin. Pitavastatin is a potent inhibitor of HMG-CoA reductase.
TMIJ-0164	Rosuvastatin-d6 Sodium Salt
	Rosuvastatin-d6 Sodium Salt 是 Rosuvastatin Sodium Salt 的氘代化合物。Rosuvastatin Sodium Salt 的 CAS 号为 1007871-86-4。
TMIJ-0150	para-Hydroxy Atorvastatin-d5 Calcium Salt
	para-Hydroxy Atorvastatin-d5 Calcium Salt 是 para-Hydroxy Atorvastatin Calcium Salt 的氘代化合物。para-Hydroxy Atorvastatin Calcium Salt 的 CAS 号为 214217-88-6。
TMIJ-0167	Simvastatin EP Impurity A-d6 Sodium Salt
	Simvastatin EP Impurity A-d6 Sodium Salt 是 Simvastatin EP Impurity A Sodium Salt 的氘代化合物。Simvastatin EP Impurity A Sodium Salt 的 CAS 号为 101314-97-0。
TMIJ-0119	Pitavastatin-d4 Sodium Salt
	Pitavastatin-d4 Sodium Salt 是 Pitavastatin Sodium Salt 的氘代化合物。Pitavastatin Sodium Salt 的 CAS 号为 574705-92-3。
TMIJ-0496	Lovastatin-d3
	Lovastatin-d3 是 Lovastatin 的氘代化合物。Lovastatin 的 CAS 号为 75330-75-5。Lovastatin是一种 HMG-CoA 还原酶抑制剂，用于降低胆固醇。
T12759	Rosuvastatin D6 Sodium	Others	Others
	Rosuvastatin D6 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
T73716	Miglustat-d9 HCl
	Miglustat-d9 (hydrochloride)为Miglustat (hydrochloride)的氘代物，属于葡萄糖神经酰胺合成酶抑制剂，主要用于治疗I型戈谢病。
T10128	(3S,5R)-Fluvastatin D6 sodium (3S,5R)-XU 62-320 D6	Others	Others
	(3S,5R)-Fluvastatin D6 sodium is the deuterium-labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM).
TMIH-0052	3S,5R-Fluvastatin-d6
	3S,5R-Fluvastatin-d6 是 3S,5R-Fluvastatin 的氘代化合物。3S,5R-Fluvastatin 的 CAS 号为 94061-81-1。
TMIJ-0149	ortho-Hydroxy Atorvastatin-d5 Lactone
	ortho-Hydroxy Atorvastatin-d5 Lactone 是 ortho-Hydroxy Atorvastatin Lactone 的氘代化合物。
TMIH-0505	Rosuvastatin-d3 intermediate
	Rosuvastatin-d3 intermediate 是 Rosuvastatin intermediate 的氘代化合物。
TMIH-0504	Rosuvastatin-d6 Calcium Salt
	Rosuvastatin-d6 Calcium Salt 是 Rosuvastatin Calcium Salt 的氘代化合物。Rosuvastatin Calcium Salt 的 CAS 号为 147098-20-2。Rosuvastatin calcium 是肝羟甲基戊二酰辅酶 A 还原酶的选择性和竞争性抑制剂，具有抗血脂活性。它降低成熟 hERG 的表达以及热休克蛋白 70 与 hERG 蛋白的相互作用，还降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go相关基因电流，延迟心脏复极化，来延长动作电位持续时间和校正 QT 间期间隔。
TMIJ-0151	Atorvastatin-d5 Calcium Salt
	Atorvastatin-d5 Calcium Salt 是 Atorvastatin Calcium Salt 的氘代化合物。Atorvastatin Calcium Salt 的 CAS 号为 134523-00-5。
T11306	Fluvastatin D6 sodium XU 62-320 (D6)	Others	Others
	Fluvastatin sodium is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin D6 sodium is deuterium labeled Fluvastatin sodium.
T11270	Febuxostat D9 非布司他D9	Others	Others
	Febuxostat D9 is deuterium labeled Febuxostat, which is a selective xanthine oxidase inhibitor with Ki of 0.6 nM.
T19551	Rosuvastatin D6 Calcium	Others	Others
	Rosuvastatin D6 Calcium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
T69966	Roxadustat-d5
	Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 µM for all). Roxadustat (10-200 µM) stabilizes HIF-1α and ...
TMIH-0506	Roxadustat-13C-15N
	Roxadustat-13C-15N 是 Roxadustat 的 13C 和 15N 的标记化合物。
TMIH-0591	Vadadustat-13C2-15N
	Vadadustat-13C2-15N 是 Vadadustat 的 13C 和 15N 的标记化合物。Vadadustat 的 CAS 号为 1000025-07-9。Vadadustat 是一种可滴定口服的缺氧诱导因子脯氨酰羟化酶 (HIF-PH) 抑制剂，是一种促红细胞生成剂，在动物慢性肾脏疾病模型中，有用于贫血的研究潜力。
TMIJ-0129	Topiroxostat-d4
	Topiroxostat-d4 是 Topiroxostat 的氘代化合物。Topiroxostat 的 CAS 号为 577778-58-6。Topiroxostat 是一种有效的口服黄嘌呤氧化还原酶 (XOR) 抑制剂，IC50=5.3 nM，Ki=5.7 nM。它还表现出弱的CYP3A4抑制活性 (18.6%)。它有用于高尿酸血症的研究潜力。
TMIJ-0152	ortho-Hydroxy Atorvastatin-d5 Calcium Salt
	ortho-Hydroxy Atorvastatin-d5 Calcium Salt 是 ortho-Hydroxy Atorvastatin Calcium Salt 的氘代化合物。ortho-Hydroxy Atorvastatin Calcium Salt 的 CAS 号为 265989-47-7。
TMIJ-0161	Febuxostat-d7
	Febuxostat-d7 是 Febuxostat 的氘代化合物。Febuxostat 的 CAS 号为 144060-53-7。Febuxostat 是一种选择性黄嘌呤氧化酶(XO)抑制剂，Ki=0.6 nM。
TMIJ-0239	Cobicistat-d8
	Cobicistat-d8 是 Cobicistat 的氘代化合物。Cobicistat 的 CAS 号为 1004316-88-4。Cobicistat 是一种细胞色素酶P450 3A 的选择性抑制剂，IC50值为30-285 nM。它是一种药代动力学增强剂，可增强抗 HIV 药物的吸收。
T12757	Rosuvastatin D3 Sodium	Others	Others
	Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
TMIH-0507	Roxadustat-13C2-15N
	Roxadustat-13C2-15N 是 Roxadustat 的 13C 和 15N 的标记化合物。

同位素标记化合物

Cat.No: T70882

Fluvastatin-d6 Sodium Salt

Cat.No: TMIH-0242

Pitavastatin D4

Cat.No: T12488

Synonym: NK-104 D4

Target: Others

Rosuvastatin-d6 Sodium Salt

Cat.No: TMIJ-0164

para-Hydroxy Atorvastatin-d5 Calcium Salt

Cat.No: TMIJ-0150

Simvastatin EP Impurity A-d6 Sodium Salt

Cat.No: TMIJ-0167

Pitavastatin-d4 Sodium Salt

Cat.No: TMIJ-0119

Cat.No: TMIJ-0496

Rosuvastatin D6 Sodium

Cat.No: T12759

Target: Others

Miglustat-d9 HCl

Cat.No: T73716

(3S,5R)-Fluvastatin D6 sodium

Cat.No: T10128

Synonym: (3S,5R)-XU 62-320 D6

Target: Others

3S,5R-Fluvastatin-d6

Cat.No: TMIH-0052

ortho-Hydroxy Atorvastatin-d5 Lactone

Cat.No: TMIJ-0149

Rosuvastatin-d3 intermediate

Cat.No: TMIH-0505

Rosuvastatin-d6 Calcium Salt

Cat.No: TMIH-0504

Atorvastatin-d5 Calcium Salt

Cat.No: TMIJ-0151

Fluvastatin D6 sodium

Cat.No: T11306

Synonym: XU 62-320 (D6)

Target: Others

Cat.No: T11270

Synonym: 非布司他D9

Target: Others

Rosuvastatin D6 Calcium

Cat.No: T19551

Target: Others

Cat.No: T69966

Roxadustat-13C-15N

Cat.No: TMIH-0506

Vadadustat-13C2-15N

Cat.No: TMIH-0591

Topiroxostat-d4

Cat.No: TMIJ-0129

ortho-Hydroxy Atorvastatin-d5 Calcium Salt

Cat.No: TMIJ-0152

Cat.No: TMIJ-0161

Cat.No: TMIJ-0239

Rosuvastatin D3 Sodium

Cat.No: T12757

Target: Others

Roxadustat-13C2-15N

Cat.No: TMIH-0507

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