10
5
12
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77627 |
Opevesostat
ODM208,ODM-208 |
P450 | Metabolism |
Opevesostat (ODM-208) 是一种裂解酶 (CYP11A1) 抑制剂(裂解酶裂解胆固醇侧链)。 | |||
T33647L |
Nesosteine Lithium
Nesosteine Lithium(84233-61-4 Free baes) |
Others | Others |
Nesosteine Lithium 是一种新型的粘液调节剂,对豚鼠 Herxheimer 微休克具有抑制作用且抑制卵清蛋白诱导的组胺在致敏动物气管中的释放。Nesosteine Lithium 能够保护致敏动物免受卵清蛋白诱导的支气管痉挛但对组胺和乙酰胆碱诱导的支气管痉挛无效。 | |||
T41032 |
Lysostaphin
|
Antibacterial | Microbiology/Virology |
Lysostaphin是一种具有强大抗葡萄球菌活性的化合物,通过三种不同的酶展现其酶促活性:glycylglycine endopeptidase、endo-β-N-acetyl glucosamidase和N-acetyl muramyl-L-alanine amidase。 | |||
T83171 |
Adamtsostatin 18
|
||
Adamtsostatin 18,一种源自含有I型血小板反应蛋白基序的抗血管生成肽,能够抑制细胞迁移和增殖。 | |||
T31481 |
Diisostearyl adipate
|
Others | Others |
Diisostearyl adipate can be used for skin care. | |||
T125532 |
Nitrosostromelin
|
Others | Others |
Nitrosostromelin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125532。 | |||
T33647 |
Nesosteine
|
Others | Others |
Nesosteine is a mucoregulatory agent. | |||
T83170 |
Adamtsostatin 4
|
||
Adamtsostatin 4为一种具有抗血管生成特性的肽类化合物,主要应用于抗血管生成相关研究领域。 | |||
T23153 |
Physostigmine hemisulfate
|
Others | Others |
cholinesterase inhibitor | |||
T78278 |
Blosozumab
|
||
Blosozumab (LY2541546)为针对人sclerostin (SOST)的单克隆抗体。它能促进骨生成,同时抑制骨吸收,可应用于骨质疏松症相关研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3332 |
Isosteviol
异甜菊醇,(-)-Isosteviol |
IL Receptor; Potassium Channel; TNF; NF-κB; Reactive Oxygen Species; COX; Topoisomerase | Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB |
Isosteviol ((-)-Isosteviol) 是一种常见的天然甜味剂,属于四环二萜糖苷,是甜菊糖苷通过酸催化水解产生的。它抑制 DNA 聚合酶和 DNA 拓扑异构酶,具有抗菌、抗癌和抗结核作用。 | |||
T0130 |
Physostigmine Salicylate
水杨酸依色林,水杨酸毒扁豆碱 |
AChR; AChE | Neuroscience |
Physostigmine salicylate 是一种可逆的乙酰胆碱酯酶抑制剂,也一种是抗胆碱能中毒的解毒剂。它可透过血脑屏障并刺激中枢胆碱能神经传递。它能逆转阿尔茨海默病转基因小鼠的记忆缺陷。 | |||
TN6252 | Isostephodeline | ||
Isostephodeline 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6252,CAS号为 56648-85-2。 | |||
T21438 |
Physostigmine
Physostol,Antilirium,Eserine,毒扁豆碱,Esromiotin,Ezerin |
Others | Others |
Physostigmine is a potent and reversible inhibitor of cholinesterase. It is also reported to form a slowly degrading carbamylated enzyme complex with acetylcholinesterase (AChE). | |||
T65262 |
Isostearic acid
|
Others | Others |
Isostearic acid 是一种天然产物,可用于生命科学领域的相关研究,其产品编号为 T65262。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00925 |
SOST Protein, Human, Recombinant (His)
VBCH,sclerostin,DAND6,CDD,SOST1 |
Human | HEK293 Cells |
SOST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1. | |||
TMPH-02886 |
SOST Protein, Mouse, Recombinant (hFc)
Sost,Sclerostin |
Mouse | HEK293 Cells |
Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. | |||
TMPJ-01294 |
SOST Protein, Mouse, Recombinant (His)
Sost,Sclerostin |
Mouse | HEK293 Cells |
Sclerostin (SOST) is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. Cerberus/DAN family members are putative BMP antagonists, and include Dan, Cerberus, Gremlin, PRDC, and Caronte. While the overall sequence identity between members of the family is low, they have conserved spacing of six cysteine residues. Cerberus and Dan have an additional cysteine residue used for dimerization; however, SOST does not and is secreted as a monomer... | |||
TMPK-00102 |
SOST Protein, Human, Recombinant (His & Avi)
VBCHsclerosteosis,SOST1,sclerostin,SOST,CD... |
Human | HEK293 Cells |
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9BQB4-1. | |||
TMPK-01293 |
SOST Protein, Cynomolgus, Recombinant (His)
VBCH,SOST1,sclerostin,DAND6,SOST,CDD,VBCHs... |
Cynomolgus | HEK293 Cells |
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 22.58 kDa and the accession number is XP_005584428.2. | |||
TMPY-01633 |
SOST Protein, Rat, Recombinant (His)
sclerostin |
Rat | HEK293 Cells |
SOST Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23 kDa and the accession number is A6HJF6. | |||
TMPK-00103 |
SOST Protein, Human, Recombinant (His & Avi), Biotinylated
VBCH,DAND6,VBCHsclerosteosis,sclerostin,SOST1,CDD,<... |
Human | HEK293 Cells |
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. SOST Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is Q9BQB4-1. | |||
TMPY-05113 |
SOST Protein, Human, Recombinant (His), Biotinylated
VBCH,SOST1,DAND6,sclerostin,CDD |
Human | HEK293 Cells |
SOST Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1. | |||
TMPH-03367 |
SOSTDC1 Protein, Rat, Recombinant (His & Myc)
Sostdc1,Sclerostin domain-containing protein 1,Wnt-... |
Rat | HEK293 Cells |
Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. SOSTDC1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 24.6 kDa and the accession number is Q642G2. | |||
TMPH-02885 |
SOSTDC1 Protein, Mouse, Recombinant (His & Myc)
Sclerostin-like protein,Sostdc1,Sclerostin domain-c... |
Mouse | E. coli |
May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. | |||
TMPK-00739 |
LRP-5 Protein, Human, Recombinant (hFc)
EVR1,BMND1,BMND1OPTA1,LRP5,LRP7,OPPG,EVR4,OPTA1,OPS,HBM,VBCH... |
Human | HEK293 Cells |
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that altered the function of the sclerostin (SOST) gene were also associated with altered human bone mass. Subsequent studies of LRP5 and sclerostin have provided important insights into the mechanisms by which these proteins regulate skeletal homeostasis. LRP-5 Protein, Human, Recomb... | |||
TMPK-00740 |
LRP-5 Protein, Human, Recombinant (mFc)
LRP7,EVR1,LR3VBCH2,HBM,LRP5,EVR4,VBCH2,OPS,BMND1OPTA1,LR3,OP... |
Human | HEK293 Cells |
A role for low-density lipoprotein-related receptor 5 (LRP5) in human bone was first established by the identification of genetic alterations that led to dramatic changes in bone mass. Shortly thereafter, mutations that altered the function of the sclerostin (SOST) gene were also associated with altered human bone mass. Subsequent studies of LRP5 and sclerostin have provided important insights into the mechanisms by which these proteins regulate skeletal homeostasis. LRP-5 Protein, Human, Recomb... |