Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01701 |
SMAD6 Protein, Human, Recombinant (His & Myc)
SMAD family member 6,Mothers against decap... |
Human | Baculovirus Insect Cells |
SMAD6 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 57.4 kDa and the accession number is O43541. | |||
TMPH-01702 |
SMAD6 Protein, Human, Recombinant (E. coli, His & Myc)
SMAD6,Mothers against decapentaplegic homo... |
Human | E. coli |
Transforming growth factor-beta superfamily receptors signaling occurs through the Smad family of intracellular mediators. SMAD6 is an inhibitory Smad (i-Smad) that negatively regulates signaling downstream of type I transforming growth factor-beta. Acts as a mediator of TGF-beta and BMP anti-inflammatory activities. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory gen... |