Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36244 |
SJF 1521
|
Others | Others |
Selective EGFR Degrader. Comprises the EGFR inhibitor lapatinib (Cat. No. 6811) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Exhibits selectivity for EGFR, including mutant forms, over HER2. Induces degradation of EGFR in OVCAR8 cells. |