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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5408 |
BI-3802
|
BCL | Apoptosis |
BI-3802 能够抑制 BCL6 的Bric-à-brac (BTB) 结构域,IC50 ≤3 nM。它可诱导 BCL6 蛋白聚集,并促进 E3 连接酶SIAH1介导的蛋白降解。BI-3802显示出抗肿瘤活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01268 |
SIAH1 Protein, Human, Recombinant (GST)
SIAH1,RING-type E3 ubiquitin transferase <... |
Human | E. coli |
SIAH1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 61.6 kDa and the accession number is Q8IUQ4. |