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Search Results for " shp 2 "

Targets Recommended: Phosphatase

27

抑制剂 & 化合物

300

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T39640	JAB-3068 SHP2-IN-6	Phosphatase	Metabolism
	JAB-3068 (SHP2-IN-6) 是一种高效的 SHP2 抑制剂，具有抗癌抗肿瘤活性，可用于研究乳腺癌肺癌和食道癌。
T40121	SHP2-D26 SHP2-D26	PROTACs	PROTAC
	SHP2-D26 is a highly potent and effective SHP2 degrader. Its mechanism of action involves the induction of SHP2 degradation through binding to VHL-1 and SHP2 proteins. Additionally, the degradation of SHP2 induced by SHP2-D26 is dependent on neddylation and proteasome activity.
T39641	SHP2-IN-6 hydrochloride SHP2-IN-6 hydrochloride	Others	Others
	SHP2-IN-6 hydrochloride is a highly potent inhibitor of SHP2 with an IC50 of 25.8 nM.
T7084	2-Bromo-4'-hydroxyacetophenone SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮	Phosphatase	Metabolism
	2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) 是一种PTP1B 的有效抑制剂，其Ki=42 μM。
T40250	SHP2 protein degrader-1 SHP2 protein degrader-1	Others	Others
	SHP2 protein degrader-1 is a highly efficient allosteric inhibitor targeting SHP2. It effectively induces degradation of SHP2 protein, resulting in cell apoptosis. This compound shows promising potential for studying diseases associated with SHP2.
T12903	SHP2 IN-1	Others	Others
	SHP2 IN-1 is an allergic SHP2 (PTPN11) inhibitor(IC50 : 3 nM).
T81162	SHP2-IN-20	Others	Others
	SHP2-IN-20 (compound 193)为SHP2抑制剂，具有3 nM的IC50值，适用于胶质母细胞瘤研究。
T79108	SHP2-IN-14	Others	Others
	SHP2-IN-14 (compound 27) 为一种口服生效SHP2变构抑制剂（IC50=7 nM），展示抗肿瘤作用。该化合物能够有效抑止小鼠NCI-H358肿瘤模型生长，且具备优良药代动力学属性和安全性。
T81161	SHP2-IN-21	Others	Others
	SHP2-IN-21（化合物208）是一种SHP2抑制剂，其IC50为3 nM，适用于胶质母细胞瘤研究。
T78694	SHP2-IN-13	Others	Others
	SHP2-IN-13是一种针对SHP2“tunnel site” 的变构抑制剂，具备高选择性及口服活性，IC50值为83.0 nM。该化合物可作为研究潜力药物，用于治疗携带RTK致癌驱动因素的癌症以及SHP2相关疾病。
T78611	SHP2-IN-5	Others	Others
	SHP2-IN-5（化合物1）为SHP2抑制剂，IC50为97 nM。SHP2，一种非受体型蛋白酪氨酸磷酸酶，与细胞生长及增殖紧密相关。SHP2-IN-5可能对抑制癌症和其他与SHP2有关的疾病具有治疗潜力。
T79412	SHP2-IN-16	Others	Others
	SHP2-IN-16（化合物222）作为SHP2抑制剂，具有1 nM的IC50值，适用于胶质母细胞瘤研究。
T78896	SHP2-IN-22	Others	Others
	SHP2-IN-22 作为变构抑制剂，靶向SHP2，具有 17.7 nM 的 IC50。该化合物能够有效抑制MIA PaCa-2胰腺癌细胞的增殖、迁移和侵袭行为。SHP2-IN-22 主要用于研究含Kirsten大鼠肉瘤病毒癌基因(KRAS)突变型的癌症。
T61891	SHP2-IN-8	Others	Others
	SHP2-IN-8 是一种可逆、非竞争性、选择性、高效性的变构SHP2抑制剂（IC50= 23 nM，Ki= 22 nM），在细胞中也有效果。SHP2-IN-8 能引起显著的热位移（ΔTm = 7.01 ℃）。SHP2-IN-8 可抑制AKT 的磷酸化，诱导 Hela 细胞凋亡 (apoptosis)。
T22276	Bis(maltolato)oxovanadium(IV) 双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)	Phosphatase; Others	Metabolism; Others
	Bis(maltolato)oxovanadium(IV) (BMOV) 是一种有效的胰岛素增敏剂，也是一种有效的、竞争性的、可逆的、口服具有活性的光谱蛋白酪氨酸磷酸酶 (PTP) 抑制剂。它抑制HCPTPA，PTP1B，HPTPβ和SHP2的IC50分别为 126 nM，109 nM，26 nM 和 201 nM。
T61701	SHP2-IN-9	Others	Others
	SHP2-IN-9 is a potent inhibitor (IC50 = 1.174 μM) specifically targeting the SHP2 protein, displaying improved penetration across the blood-brain barrier. It exhibits a remarkable 85-fold selectivity for SHP2 over SHP1. By inhibiting SHP2-mediated cell signal transduction and impairing cancer cell proliferation, SHP2-IN-9 effectively suppresses the growth of both cervix cancer tumors and glioblastoma in vivo [1].
T81164	SHP2-IN-18	Others	Others
	SHP2-IN-18（化合物183）作为SHP2抑制剂，具有3 nM的IC50。该化合物适用于胶质母细胞瘤研究。
T81163	SHP2-IN-19	Others	Others
	SHP2-IN-19（compound 183），作为SHP2抑制剂，展现出3 nM的IC50值，主要应用于胶质母细胞瘤研究。
T81165	SHP2-IN-17	Others	Others
	SHP2-IN-17（化合物192）作为SHP2抑制剂，具有2 nM的IC50值，适用于胶质母细胞瘤研究。
T74430	SHP2 protein degrader-2	PROTACs	PROTAC
	SHP2protein degrader-2 (SHP2-D26) 是一种SHP2蛋白PROTAC 降解剂。SHP2protein degrader-2 可降低各种癌细胞中SHP2的表达水平。
T72839	SHP2/HDAC-IN-1	Others	Others
	SHP2/HDAC-IN-1 是一种变构的 SHP2/HDAC 双重抑制剂，IC50值分别为 20.4 nM (SHP2) 和 25.3 nM ( HDAC1)。SHP2/HDAC-IN-1 通过激活 T 细胞、增强抗原呈递功能和促进细胞因子分泌来触发抗肿瘤免疫反应。SHP2/HDAC-IN-1 可用于癌症的免疫治疗研究。
T72836	SHP2/CDK4-IN-1	Others	Others
	SHP2/CDK4-IN-1（化合物10）是一种针对SHP2和CDK4的口服双重抑制剂，具有IC50值分别为4.3和18.2 nM。该化合物能有效引起G0/G1期阻滞，抑制TNBC细胞的增殖，并在EMT6同源小鼠模型中展现出明显的抗肿瘤活性，适用于三阴性乳腺癌（TNBC）的研究。
T63993	SHP2 inhibitor LY6	Others	Others
	SHP2 inhibitor LY6 (LY6) 是一种有效的、选择性的 SHP2 抑制剂 (IC50: 9.8 μM)。SHP2 inhibitor LY6 能够阻碍 SHP2 介导的细胞信号传导和增殖。
T6911	NSC-87877 disodium NSC87877	Apoptosis; Phosphatase	Apoptosis; Metabolism
	NSC-87877 disodium (NSC87877) 是一种有效的Shp2和Shp1蛋白质酪氨酸磷酸酶抑制剂，IC50值分别为0.318 μM 和0.355 μM。NSC-87877还抑制双特异性磷酸酶26。
T13013	Sodium stibogluconate Stibogluconate trisodium nonahydrate,葡萄糖酸锑钠	Phosphatase	Metabolism
	Sodium stibogluconate (Stibogluconate trisodium nonahydrate) 是一种有效的蛋白酪氨酸磷酸酶 (phosphatase) 抑制剂。它在10，100 和 100 μg/mL 时分别抑制 99% 的 SHP-1，SHP-2 和 PTP1B 活性。
T7541	PTP inhibitor 1 PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮	Phosphatase	Metabolism
	PTP inhibitor 1 是蛋白酪氨酸磷酸酶 (PTP) 抑制剂，具有抗血管生成作用。
T22137	PTP Inhibitor IV	Others	Others
	PTP Inhibitor IV 是一种有效的蛋白酪氨酸磷酸酶 (PTP) 抑制剂，可选择性抑制 DUSP14 磷酸酶活性（IC50 ： 5.21 μM）。PTP Inhibitor IV 对 SHP-2、PTP1B、PTP-ε、PTP Meg-2、PTP-σ、PTP-β 和 PTP-μ具有抑制作用，IC50 分别为 1.8 μM、2.5 μM、8.4 μM、13 μM、20 μM、6.4 μM，和 6.7 μM。PTP Inhibitor IV 通过抑制PTP 活性，影响细胞信号传导，并可能调节与PTP 介导的信号传导事件相关的特定途径。

化合物

Cat.No: T39640

Synonym: SHP2-IN-6

Target: Phosphatase

Cat.No: T40121

Synonym: SHP2-D26

Target: PROTACs

SHP2-IN-6 hydrochloride

Cat.No: T39641

Synonym: SHP2-IN-6 hydrochloride

Target: Others

2-Bromo-4'-hydroxyacetophenone

Cat.No: T7084

Synonym: SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮

Target: Phosphatase

SHP2 protein degrader-1

Cat.No: T40250

Synonym: SHP2 protein degrader-1

Target: Others

Cat.No: T12903

Target: Others

Cat.No: T81162

Target: Others

Cat.No: T79108

Target: Others

Cat.No: T81161

Target: Others

Cat.No: T78694

Target: Others

Cat.No: T78611

Target: Others

Cat.No: T79412

Target: Others

Cat.No: T78896

Target: Others

Cat.No: T61891

Target: Others

Bis(maltolato)oxovanadium(IV)

Cat.No: T22276

Synonym: 双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)

Target: Phosphatase, Others

Cat.No: T61701

Target: Others

Cat.No: T81164

Target: Others

Cat.No: T81163

Target: Others

Cat.No: T81165

Target: Others

SHP2 protein degrader-2

Cat.No: T74430

Target: PROTACs

SHP2/HDAC-IN-1

Cat.No: T72839

Target: Others

SHP2/CDK4-IN-1

Cat.No: T72836

Target: Others

SHP2 inhibitor LY6

Cat.No: T63993

Target: Others

NSC-87877 disodium

Cat.No: T6911

Synonym: NSC87877

Target: Apoptosis, Phosphatase

Sodium stibogluconate

Cat.No: T13013

Synonym: Stibogluconate trisodium nonahydrate,葡萄糖酸锑钠

Target: Phosphatase

PTP inhibitor 1

Cat.No: T7541

Synonym: PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮

Target: Phosphatase

PTP Inhibitor IV

Cat.No: T22137

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03125	SHP-2 Protein, Mouse, Recombinant (His) SAP-2,Syp,PTP1D,SH-PTP2,SH-PTP3,SHP	Mouse	HEK293 Cells
	SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric acid monoesters. They dephosphorylate EGFR, JAK2 and TYK2 kinases, promoting oncogenic transformation. SHP2 is widely expressed, with highest levels in heart, brain, and skeletal muscle. SHP2 acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participat...
TMPY-02388	SIRP beta 1 Protein, Mouse, Recombinant (His) SIRP-beta,SIRP-β,99327N5Rik,Sirpb,Sirpb1,Sirpb1a,SI...	Mouse	HEK293 Cells
	SIRPB1A (Signal-regulatory protein beta 1A), also known as SIRP beta 1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily. Signal-regulatory proteins (SIRPs) are cell-surface glycoproteins expressed on myeloid and neural cells that have been shown to recruit SH2 domain-containing protein phosphatase 1 (SHP-1) and SHP-2 and to regulate receptor tyrosine kinase-coupled signaling. SIRP are classified as SIRP alpha molecules, containing 11- to 113-amino acid long, or...
TMPK-01066	BTLA Protein, Human, Recombinant (His & Avi) BTLA,BTLA1,FLJ16065,CD272,MGC1297...	Human	HEK293 Cells
	B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. BTLA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight ...
TMPK-00530	BTLA Protein, Cynomolgus, Recombinant (His) MGC129743,CD272,BTLA,BTLA1,FLJ160...	Cynomolgus	HEK293 Cells
	B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. BTLA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 15...
TMPH-03267	CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO) Clm1,Cd300lf,CD300 antigen-like family member F,CLM-1,CD300f...	Rat	E. coli
	Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell ...
TMPJ-00552	LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated Leukocyte Immunoglobulin-Like Receptor 2,Monocyte/M...	Human	HEK293 Cells
	Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa...
TMPJ-00712	MPZL1 Protein, Human, Recombinant (His) FLJ96614,mRNA,Myelin protein zero-like 1,cDNA FLJ78597,cDNA,...	Human	HEK293 Cells
	Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin...
TMPJ-00226	SLAMF1 Protein, Mouse, Recombinant (His) signaling lymphocytic activation molecule,SLAM family member...	Mouse	HEK293 Cells
	Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been...
TMPY-00891	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-02096	TACI Protein, Human, Recombinant (His) RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor...	Human	HEK293 Cells
	TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His) Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...	Human	E. coli
	KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-01442	DMBT1 Protein, Human, Recombinant (His) GP340,deleted in malignant brain tumors 1,muclin	Human	HEK293 Cells
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPY-02011	CD96 Protein, Human, Recombinant (His) CD96 molecule,TACTILE	Human	HEK293 Cells
	CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-01717	VEGF164 Protein, Mouse, Recombinant vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子	Mouse	Baculovirus Insect Cells
	VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPY-00341	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-01613	Periostin/OSF-2 Protein, Mouse, Recombinant (His) A630052E07Rik,OSF-2,Osf2,PLF,AI74...	Mouse	HEK293 Cells
	Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Protein T1,suppression of tumorigenicity 2,Ly84,DER...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His) SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,AP...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-00751	TrkB Protein, Human, Recombinant (His) trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...	Human	HEK293 Cells
	TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-05288	PLGF/PGF Protein, Human, Recombinant (aa 19-149) PLGF,PGFL,placental growth factor,D12S1900,SHGC-107...	Human	E. coli
	PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-04844	BTN3A1 Protein, Human, Recombinant (His) BTN3.1,butyrophilin subfamily 3 member A1,BTF5,BT3.1,CD2...	Human	HEK293 Cells
	BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His) KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene homolog,RAL...	Human	E. coli
	KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-02820	SDF-1/CXCL12 Protein, Human, Recombinant (isoform a) SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1	Human	E. coli
	SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST) v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01935	c-Kit Protein, Human, Recombinant (His) PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...	Human	HEK293 Cells
	c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPY-04644	PDGFB Protein, Human, Recombinant (His) platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...	Human	P. pastoris (Yeast)
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-01985	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated FCGR2,FCGR21,CD32A,FCG2,...	Human	HEK293 Cells
	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-04356	GSK3B Protein, Human, Recombinant (His) glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β	Human	Baculovirus Insect Cells
	GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPY-02500	YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) Gp39,AW208766,Brp39,chitinase 3 like 1	Mouse	HEK293 Cells
	YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
TMPY-05414	NKG2D/CD314 Protein, Mouse, Recombinant (hFc) D6H12S2489E,NKG2-D,killer cell le...	Mouse	Baculovirus Insect Cells
	NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-01871	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) interleukin 5 receptor, alpha,IL5R,CD125,CDw12<...	Human	HEK293 Cells
	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293) HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot...	Human	HEK293 Cells
	GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His) IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 recepto...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His) KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...	Human	E. coli
	KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-00747	Nectin-2 Protein, Human, Recombinant (His) PVRR2,Nectin-2,poliovirus receptor-related...	Human	HEK293 Cells
	Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-04051	c-Kit Protein, Human, Recombinant (hFc) SCFR,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene h...	Human	HEK293 Cells
	c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
TMPY-05427	CD19 Protein, Human, Recombinant (hFc) CVID3,B4,CD19 molecule	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His) TGFR-2,TGF-beta type II receptor,Transforming growt...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-00127	M-CSF/CSF1 Protein, Human, Recombinant 集落刺激因子,CSF-1,MCSF,M-CSF,colony stimulating factor 1 (macroph...	Human	HEK293 Cells
	M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His) NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-RAS2	Human	E. coli
	KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-02432	VEGF164 Protein, Rat, Recombinant 血管内皮生长因子,vascular endothelial growth factor A	Rat	Baculovirus Insect Cells
	VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
TMPY-02231	TrkB Protein, Mouse, Recombinant (His) trk-B,neurotrophic tyrosine kinase, receptor, type 2	Mouse	HEK293 Cells
	TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant ST2,IL1RL1,ST2L,IL33R,T1,DER4,ST2...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
TMPY-02367	Neuropilin-1 Protein, Human, Recombinant (isoform b, His) neuropilin 1,NRP,VEGF165R,BDCA4,Neuropilin-1,NP1,CD304	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (isoform b, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is O14786-2.
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) ST2V,FIT-1,DER4,interleukin 1 receptor-like 1,T1,IL...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPY-04829	G-CSF Protein, Human, Recombinant G-CSF,colony stimulating factor 3 (granulocyte),集落刺激因子,CSF3O...	Human	HEK293 Cells
	G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
TMPY-00871	LAYN Protein, Human, Recombinant (hFc) layilin	Human	HEK293 Cells
	LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2.
TMPY-01199	CD74 Protein, Human, Recombinant (His) II,DHLAG,Ia-GAMMA,CD74 molecule, major histocompatibility co...	Human	HEK293 Cells
	CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
TMPY-00005	FGF-8a Protein, Human, Recombinant fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-03425	Tau Protein, Human, Recombinant (His) PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-as...	Human	E. coli
	MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
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重组蛋白

SHP-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03125

Species: Mouse

Expression System: HEK293 Cells

SIRP beta 1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02388

Species: Mouse

Expression System: HEK293 Cells

BTLA Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-01066

Species: Human

Expression System: HEK293 Cells

BTLA Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00530

Species: Cynomolgus

Expression System: HEK293 Cells

CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03267

Species: Rat

Expression System: E. coli

LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated

Cat.No: TMPJ-00552

Species: Human

Expression System: HEK293 Cells

MPZL1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00712

Species: Human

Expression System: HEK293 Cells

SLAMF1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00226

Species: Mouse

Expression System: HEK293 Cells

Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

Cat.No: TMPY-00891

Species: Human

Expression System: HEK293 Cells

TACI Protein, Human, Recombinant (His)

Cat.No: TMPY-02096

Species: Human

Expression System: HEK293 Cells

KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Cat.No: TMPY-04113

Species: Human

Expression System: E. coli

DMBT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01442

Species: Human

Expression System: HEK293 Cells

CD96 Protein, Human, Recombinant (His)

Cat.No: TMPY-02011

Species: Human

Expression System: HEK293 Cells

VEGF164 Protein, Mouse, Recombinant

Cat.No: TMPY-01717

Species: Mouse

Expression System: Baculovirus Insect Cells

FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

Cat.No: TMPY-00341

Species: Human

Expression System: HEK293 Cells

Periostin/OSF-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01613

Species: Mouse

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Cat.No: TMPJ-00850

Species: Mouse

Expression System: HEK293 Cells

Clusterin Protein, Human, Recombinant (CLU34, His)

Cat.No: TMPY-01691

Species: Human

Expression System: HEK293 Cells

TrkB Protein, Human, Recombinant (His)

Cat.No: TMPY-00751

Species: Human

Expression System: HEK293 Cells

PLGF/PGF Protein, Human, Recombinant (aa 19-149)

Cat.No: TMPY-05288

Species: Human

Expression System: E. coli

BTN3A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04844

Species: Human

Expression System: HEK293 Cells

KRAS Protein, Human, Recombinant (G12D, His)

Cat.No: TMPY-06056

Species: Human

Expression System: E. coli

SDF-1/CXCL12 Protein, Human, Recombinant (isoform a)

Cat.No: TMPY-02820

Species: Human

Expression System: E. coli

C-ABL/ABL1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04396

Species: Human

Expression System: Baculovirus Insect Cells

c-Kit Protein, Human, Recombinant (His)

Cat.No: TMPY-01935

Species: Human

Expression System: HEK293 Cells

PDGFB Protein, Human, Recombinant (His)

Cat.No: TMPY-04644

Species: Human

Expression System: P. pastoris (Yeast)

CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-01985

Species: Human

Expression System: HEK293 Cells

GSK3B Protein, Human, Recombinant (His)

Cat.No: TMPY-04356

Species: Human

Expression System: Baculovirus Insect Cells

YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02500

Species: Mouse

Expression System: HEK293 Cells

NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-05414

Species: Mouse

Expression System: Baculovirus Insect Cells

IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)

Cat.No: TMPY-01871

Species: Human

Expression System: HEK293 Cells

GDNF Protein, Human, Recombinant (HEK293)

Cat.No: TMPY-02792

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01359

Species: Human

Expression System: HEK293 Cells

KRAS Protein,Human, Recombinant (Q61H, His)

Cat.No: TMPY-01888

Species: Human

Expression System: E. coli

Nectin-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00747

Species: Human

Expression System: HEK293 Cells

c-Kit Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04051

Species: Human

Expression System: HEK293 Cells

CD19 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05427

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00335

Species: Mouse

Expression System: HEK293 Cells

M-CSF/CSF1 Protein, Human, Recombinant

Cat.No: TMPY-00127

Species: Human

Expression System: HEK293 Cells

KRAS Protein,Human,Recombinant(G12C & Q61H, His)

Cat.No: TMPY-04116

Species: Human

Expression System: E. coli

VEGF164 Protein, Rat, Recombinant

Cat.No: TMPY-02432

Species: Rat

Expression System: Baculovirus Insect Cells

TrkB Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02231

Species: Mouse

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant

Cat.No: TMPY-00850

Species: Human

Expression System: HEK293 Cells

Neuropilin-1 Protein, Human, Recombinant (isoform b, His)

Cat.No: TMPY-02367

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00849

Species: Human

Expression System: HEK293 Cells

G-CSF Protein, Human, Recombinant

Cat.No: TMPY-04829

Species: Human

Expression System: HEK293 Cells

LAYN Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00871

Species: Human

Expression System: HEK293 Cells

CD74 Protein, Human, Recombinant (His)

Cat.No: TMPY-01199

Species: Human

Expression System: HEK293 Cells

FGF-8a Protein, Human, Recombinant

Cat.No: TMPY-00005

Species: Human

Expression System: E. coli

Tau Protein, Human, Recombinant (His)

Cat.No: TMPY-03425

Species: Human

Expression System: E. coli

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