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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36536 |
SH-42
|
Others | Others |
SH-42 是一种人Δ24-脱氢胆固醇还原酶 (DHCR24) 抑制剂(IC50:42 nM),具有选择性和高效性,可诱导血浆去甲基铁醇含量增加。 | |||
T64137 |
AChE/BuChE-IN-3
|
Others | Others |
AChE/BuChE-IN-3 是一种有效的、能够透过血脑屏障的 AChE (IC50: 0.65 μM) 与 BuChE (IC50: 5.77 μM) 抑制剂,对 Aβ1-42 的聚集也表现出抑制作用。AChE/BuChE-IN-3 表现出有效的神经保护活性,对 SH-SY5Y 细胞几乎没有毒性。AChE/BuChE-IN-3 能够用于研究阿尔兹海默症。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03296 |
SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)
SH-PTP1,Hcph,70Z-SHP,Ptp1C,protein tyrosin... |
Mouse | Baculovirus Insect Cells |
PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of PTPN6 contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of PTPN6 with its substrates. PTPN6 is expressed primarily in hematopoietic cells, and functions as an ... |