Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3700 |
SCH900776 (S-isomer)
MK-8776 S-isomer,SCH900776 S-isomer |
Chk; CDK | Cell Cycle/Checkpoint |
SCH900776 S-isomer (MK-8776 S-isomer) 是SCH900776的S 型同分异构体。 | |||
T30261 |
AZD6482 (S-isomer)
AZD-6482,AZD 6482,AZD6482 (S),AZD6482 |
Others | Others |
AZD6482 (S-isomer) is a potent, selective, ATP-competitive PI3Kβ inhibitor (IC(50) 0.01 μm), which can inhibit insulin-induced in vitro glucose uptake by human adipocytes (IC(50) is 4.4 μm). | |||
T19571 |
T3-ATA (S-isomer)
|
Others | Others |
T3-ATA S-isomer, the S-isomer of T3-ATA, represents the active form of the thyroid hormone. | |||
T2517 |
SCH900776
MK 8776,MK-8776 |
Chk; CDK | Cell Cycle/Checkpoint |
SCH900776 (MK-8776) 是一种靶向细胞周期检查点激酶 1(Chk1) 的抑制剂,IC50值为 3 nM。它比对 CDK2 和 Chk2 的选择性分别高 50 和 500 倍,具有潜在的放射增敏和化学增敏活性。 |