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Search Results for " sc 1 "

Targets Recommended: ERK Raf S6 Kinase

31

抑制剂 & 化合物

3

天然产物

1735

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T6948	Pluripotin SC1	ERK; Raf; S6 Kinase	MAPK; PI3K/Akt/mTOR signaling
	Pluripotin (SC1) 是ERK1和RasGAP 的双重抑制剂，KD 分别为 98 和 212 nM。它还抑制RSK1、RSK2、RSK3和RSK4，IC50分别为 0.5、2.5、3.3 和 10.0 μM。
T2253	TCS PIM-1 1 3-氰基-4-苯基-6-(3-溴-6-羟基苯基)-2(1H)-吡啶酮,SC 204330	Pim	Chromatin/Epigenetic; JAK/STAT signaling
	TCS PIM-1 1 (SC 204330) 是一种特异性有效的 ATP 竞争性 Pim-1 激酶抑制剂，IC50为 50 nM，对 MEK1/MEK2 和 Pim-2 表现出良好的特异性，IC50值大于 20000 nM。
T8478	SC-43	Apoptosis; Phosphatase; STAT	Apoptosis; JAK/STAT signaling; Metabolism; Stem Cells
	SC-43 是一种具有口服活性的SHP-1 (PTPN6)激动剂。它是Sorafenib 的衍生物，可抑制STAT3的磷酸化并诱导细胞凋亡，具有抗纤维化和抗癌作用。
T2659	GW2580 GW 2580,SC-203877	c-Fms	Tyrosine Kinase/Adaptors
	GW2580 (SC-203877) 是一种口服有效的、选择性的 c-Fms 激酶抑制剂，体外实验中在 0.06 μM 时可完全抑制人 cFMS 激酶。它是 ATP 与 cFMS 激酶结合的竞争性抑制剂，能够抑制集落刺激因子 1 信号传导。
T2274	SC79 SC 79,2-氨基-6-氯-alpha-氰基-3-(乙氧羰基)-4H-1-苯并吡喃-4-乙酸乙酯	Akt	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	SC79 是一个 AKT 激动剂，具有特异性和血脑屏障渗透性。SC79 可以特异性结合 AKT 的 PH 结构域，激活胞质中 AKT，并抑制 AKT 膜转位。SC79 具有神经保护活性。
T2257	AdipoRon SC-396658,2-(4-苯甲酰苯氧基)-N-[1-(苯基甲基)-4-哌啶基]乙酰胺	Adiponectin receptor	GPCR/G Protein
	AdipoRon (SC-396658) 是可口服的脂联素受体激动剂，能够与AdipoR1(Kd:1.8 μM)及AdipoR2(Kd:3.1 μM)结合。
T23333	SC-58125 SC 58125,1-[(4-甲基磺酰基)苯基]-3-三氟甲基-5-(4-氟苯基)吡唑	COX	Immunology/Inflammation; Neuroscience
	SC-58125 是一种选择性的环氧合酶2 (COX-2)的抑制剂，IC50值为 0.04 μM。它在体内外均表现出抗肿瘤活性，还可抑制炎症部位的水肿并具有缓解疼痛作用。
T2234	TCS JNK 5a N-(3-氰基-4,5,6,7-四氢苯并[b]噻吩-2-基)-1-萘甲酰胺,SC202671,SC 202671,N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide,JNK Inhibitor IX,SC-202671	Apoptosis; JNK	Apoptosis; MAPK
	TCS JNK 5a (SC202671) 是一种 JNK2和 JNK3的有效抑制剂，pIC50分别为 6.5和 6.7。
T12856	SC-26196 ALPHA,ALPHA-二苯基-4-[(3-吡啶亚甲基)氨基]-1-吡嗪戊腈	Others	Others
	SC-26196 是一种 Delta6 去饱和酶 (D6D, FADS2) 抑制剂 (在大鼠肝微粒体中，IC50=0.2 µM)，具有口服活性，具有抗炎作用。
T22424	1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	SC-1 是一种 Sorafenib 的衍生物，可抑制 STAT3磷酸化，通过依赖 SHP-1 的 STAT3失活诱导细胞凋亡，具有抗癌作用。
T9743	FEN1-IN-SC13	Others	Others
	FEN1-IN-SC13 是有效的DNA 片段化核酸内切酶 1 抑制剂。
T9545	Compound 1T-0219 (SC)	FAK	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Compound 1T-0219 (SC) 是一种 AKT1-FAK 相互作用的阻断剂，可减少对人 SW620 结肠癌细胞中细胞外压力的 FAK 磷酸化的刺激，而不影响基础 FAK 磷酸化。
T18678	SC-VC-PAB-DM1	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	SC-VC-PAB-DM1 is a drug-linker conjugate utilized in Antibody-Drug Conjugates (ADC), featuring DM1 (Mertansine, a tubulin inhibitor) linked through the SC-VC-PAB[1] ADC linker to deliver potent antitumor activity.
T70476	SML-10-70-1	Others	Others
	SML-10-70-1 is a Novel Active Site Inhibitor of Oncogenic K-Ras G12C.
T62921	EBNA1-IN-SC7	Others	Others
	EBNA1-IN-SC7 (compound SC7) 是一种 Epstein-Barr nuclear antigen 1 (EBNA1) 的选择性抑制剂，能够干扰 EBNA1-DNA 结合活性 (IC50: 23 μM)。EBNA1-IN-SC7 能够用于研究 EBV (Epstein-Barr virus) 相关癌症。
T84827	SC209 intermediate-1	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	SC209 intermediate-1（Compound A7a）为ADC连接子，用于ADC合成。
T0697	Aspartame 阿斯巴甜,SC-18862	Others; Taste receptor	Metabolism; Others
	Aspartame (SC-18862) 是一种二肽的甲酯，由苯丙氨酸 (50%)，天门冬氨酸 (40%) 和甲醇 (10%) 组成。它可用作合成的非营养性甜味剂。
T8505	SC-236 4-(5-(4-氯苯基)-3-(三氟甲基)-1H-,Sc 236	Apoptosis; COX; PPAR	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience
	SC-236 (Sc 236) 是一种具有口服活性的COX-2特异性抑制剂和PPARγ激动剂。它可通过 c-Jun 氨基端抑制激活蛋白-1活性，在小鼠模型中通过抑制 ERK 的磷酸化发挥抗炎作用。
T4101	SC-560 SC560	COX	Immunology/Inflammation; Neuroscience
	SC-560 是一种选择性 COX-1抑制剂，IC50值为 9 nM。
T23331	SC 51089 SC 51089 free base	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	SC 51089 是一种选择性的前列腺素受体 PGE2 拮抗剂，对前列腺素受体亚型具有选择性，具有抗伤害活性，可改善亨廷顿病 R6/1 小鼠模型中的运动缺陷并挽救记忆力下降。
T4100	AS8351 NSC51355,AS-8351,AS 8351	Histone Demethylase	Chromatin/Epigenetic
	AS8351 (NSC51355) 是一种组蛋白去甲基化酶抑制剂，可以诱导人胎儿肺成纤维细胞重编程为功能性心肌细胞。
T0219	Valdecoxib 伐地考昔,代他考昔,SC 65872	COX	Immunology/Inflammation; Neuroscience
	Valdecoxib (SC 65872) 是可口服的高选择性 COX-2抑制剂，对 COX-2 和 COX-1 的 IC50值分别为 5 nM 和 140 μM，可用于治疗骨关节炎、类风湿性关节炎以及痛经和经期症状。
T28697	SC-2001 SC2001	Others	Others
	SC-2001 is a MCL-1 inhibitor. SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells. SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellu
T18679	SC-VC-PAB-MMAE	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	SC-VC-PAB-MMAE is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor) connected through the cleavable linker SC-VC-PAB[1].
T78547	2-Phenyl-2-(2-pyridyl)acetonitrile α-Phenyl-2-pyridineacetonitrile	Drug Metabolite	Metabolism
	2-Phenyl-2-(2-pyridyl)acetonitrile 是 SC 15396 在大鼠肝脏匀浆上清中的主要代谢产物，后者为一种胃分泌抑制剂，作用于抗胃泌素受体。
T77163	Pexelizumab
	Pexelizumab (h5G1.1-SC)为一种针对C5补体成分的人源化单克隆抗体。该化合物可抑制凋亡(apoptosis)和白细胞浸润，常用于研究脑缺血再灌注损伤和心肌梗死。
T75285	Metronidazole hydrochloride	Others	Others
	Metronidazole hydrochloride (SC 326421) 是一种有口服活性的硝基咪唑抗生素，适用于厌氧微生物感染的研究。该化合物能穿越血脑屏障，长期服用可能引发炎症和骨骼肌收缩问题。
T36374	Naloxegol (NKTR-118)	Others	Others
	Naloxegol (NKTR-118; AZ-13337019) is an opioid-receptor antagonist[1]. [1]. Yoon SC, et al. Naloxegol in opioid-induced constipation: a new paradigm in the treatment of a common problem. Patient Prefer Adherence. 2017 Jul 24;11:1265-1271.
T75766	GP(33-41) TFA
	GP(33-41) TFA 是一种由 9 个氨基酸残基组成的多肽，它是淋巴细胞性脉络丛脑膜炎病毒 GP1 抗原决定基中的序列。GP(33-41) TFA 能够上调 RMA-S (Db Kb) 细胞表面 H-2Db 分子，SC50值为 344 nM。
T36822	Benzovindiflupyr	Others	Others
	Benzovindiflupyr is a fungicide.1It inhibits mitochondrial complex II, also known as succinate dehydrogenase (SDH; IC50= 5.2 nM), and mycelial growth ofS. sclerotiorum(EC50= 0.011 μg/ml). Benzovindiflupyr (60 μg/ml) completely protects eggplant leaves fromS. sclerotioruminfection. Formulations containing benzovindiflupyr have been used to control various fungal diseases in agriculture. 1.Gao, Y., He, L., Zhu, J., et al.The relationship between features enabling SDHI fungicide binding to the Sc-S...
T36996	MSA-2 dimer	Others	Others
	MSA-2 dimer is a selective, orally active non-nucleotide STING agonist (Kd=145 μM) with long-term antitumor and immunogenic activity. MSA-2 dimer is bound to STING as a non-covalent dimer exhibiting higher permeability than cyclic dinucleotide[1]. MSA-2 dimer (60 mg/kg; p.o.; 50 days) inhibits tumor growth and prolongs overall survival[1]. MSA-2 dimer (40 mg/kg; s.c.; 25 days) induces complete tumor regression[1].MSA-2 dimer (60 mg/kg; p.o.; 4 hours) increases proinflammatory cytokine (IFN-β) le...

化合物

Cat.No: T6948

Synonym: SC1

Target: ERK, Raf, S6 Kinase

Cat.No: T2253

Synonym: 3-氰基-4-苯基-6-(3-溴-6-羟基苯基)-2(1H)-吡啶酮,SC 204330

Target: Pim

Cat.No: T8478

Target: Apoptosis, Phosphatase, STAT

Cat.No: T2659

Synonym: GW 2580,SC-203877

Target: c-Fms

Cat.No: T2274

Synonym: SC 79,2-氨基-6-氯-alpha-氰基-3-(乙氧羰基)-4H-1-苯并吡喃-4-乙酸乙酯

Target: Akt

Cat.No: T2257

Synonym: SC-396658,2-(4-苯甲酰苯氧基)-N-[1-(苯基甲基)-4-哌啶基]乙酰胺

Target: Adiponectin receptor

Cat.No: T23333

Synonym: SC 58125,1-[(4-甲基磺酰基)苯基]-3-三氟甲基-5-(4-氟苯基)吡唑

Target: COX

Cat.No: T2234

Synonym: N-(3-氰基-4,5,6,7-四氢苯并[b]噻吩-2-基)-1-萘甲酰胺,SC202671,SC 202671,N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide,JNK Inhibitor IX,SC-202671

Target: Apoptosis, JNK

Cat.No: T12856

Synonym: ALPHA,ALPHA-二苯基-4-[(3-吡啶亚甲基)氨基]-1-吡嗪戊腈

Target: Others

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

Cat.No: T22424

Target: Apoptosis, STAT

Cat.No: T9743

Target: Others

Compound 1T-0219 (SC)

Cat.No: T9545

Target: FAK

Cat.No: T18678

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T70476

Target: Others

Cat.No: T62921

Target: Others

SC209 intermediate-1

Cat.No: T84827

Target: Others, ADC Linker

Cat.No: T0697

Synonym: 阿斯巴甜,SC-18862

Target: Others, Taste receptor

Cat.No: T8505

Synonym: 4-(5-(4-氯苯基)-3-(三氟甲基)-1H-,Sc 236

Target: Apoptosis, COX, PPAR

Cat.No: T4101

Synonym: SC560

Target: COX

Cat.No: T23331

Synonym: SC 51089 free base

Target: Prostaglandin Receptor

Cat.No: T4100

Synonym: NSC51355,AS-8351,AS 8351

Target: Histone Demethylase

Cat.No: T0219

Synonym: 伐地考昔,代他考昔,SC 65872

Target: COX

Cat.No: T28697

Synonym: SC2001

Target: Others

Cat.No: T18679

Target: Others, Drug-Linker Conjugates for ADC

2-Phenyl-2-(2-pyridyl)acetonitrile

Cat.No: T78547

Synonym: α-Phenyl-2-pyridineacetonitrile

Target: Drug Metabolite

Cat.No: T77163

Metronidazole hydrochloride

Cat.No: T75285

Target: Others

Naloxegol (NKTR-118)

Cat.No: T36374

Target: Others

Cat.No: T75766

Benzovindiflupyr

Cat.No: T36822

Target: Others

Cat.No: T36996

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN6754	1-Nonadecanol	Others	Others
	1-Nonadecanol 是一种 Heracleum thomsonii 的超临界二氧化碳精油的成分，也是 Neotinea ustulata 的重要香气化合物。
T4943	Monoolein 1-Oleoyl-rac-glycerol,甘油单油酸酯	Others; Endogenous Metabolite	Metabolism; Others
	Monoolein (1-Oleoyl-rac-glycerol) 是内源性代谢产物的一种。
T4973	Paraxanthine 1,7-二甲基黄嘌呤,1,7-DIMETHYLXANTHINE	Endogenous Metabolite	Metabolism
	Paraxanthine (1,7-dimethylxanthine) 是一种 caffeine 的代谢物，能够刺激Ryanodine 受体通道来抑制多巴胺能细胞的死亡。

天然产物

Cat.No: TN6754

Target: Others

Cat.No: T4943

Synonym: 1-Oleoyl-rac-glycerol,甘油单油酸酯

Target: Others, Endogenous Metabolite

Cat.No: T4973

Synonym: 1,7-二甲基黄嘌呤,1,7-DIMETHYLXANTHINE

Target: Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01031	CD166/ALCAM Protein, Mouse, Recombinant (His & hFc) CD166,AI853494,MuSC,DM-GRASP,BEN,activated...	Mouse	HEK293 Cells
	CD166/ALCAM Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 84.2 kDa and the accession number is Q54AJ5.
TMPY-01153	CD166/ALCAM Protein, Mouse, Recombinant (His) MuSC,CD166,SC1,activated...	Mouse	HEK293 Cells
	CD166/ALCAM Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is Q54AJ5.
TMPJ-01368	GPC1 Protein, Mouse, Recombinant (His) Gpc1,Glypican-1	Mouse	HEK293 Cells
	Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated sig...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) AMPK, AMPK(α1, β1, γ1)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-02030	CD82 Protein, Human, Recombinant (His) CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...	Human	HEK293 Cells
	CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-01894	SIGIRR Protein, Human, Recombinant (His) TIR8,single immunoglobulin and toll-interleukin 1 r...	Human	HEK293 Cells
	SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01247	FLT3 Protein, Human, Recombinant (T227M, His) FLK2,FLK-2,CD135,STK1,fms-related tyrosine...	Human	HEK293 Cells
	FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) thyroid peroxidase,MSA,TPX,TDH2A	Human	Baculovirus Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-03290	HGF Protein, Mouse, Recombinant hepatocyte growth factor (hepapoietin A,NK1,sc<...	Mouse	HEK293 Cells
	HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc) WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...	Human	HEK293 Cells
	TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-01147	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) RSPO,CRISTIN3,R-spondin 1	Human	HEK293 Cells
	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-04346	PD-L2 Protein, Human, Recombinant (His) PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00947	VCAM-1 Protein, Human, Recombinant (hFc) INCAM-100,CD106,VCAM-1,vasc	Human	HEK293 Cells
	VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-01949	CD19 Protein, Human, Recombinant (His) CD19 molecule,B4,CVID3	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-04165	FGFR3 Protein, Human, Recombinant (His) JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-00820	IgG1 Fc Protein, Human, Recombinant (C103S) Ighg1,IgG1 Fc	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His) HHF5,CD220,insulin receptor	Human	HEK293 Cells
	Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-04348	CTLA-4 Protein, Human, Recombinant (His) ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-02813	ErbB4 Protein, Human, Rhesus, Recombinant (His) erb-b2 receptor tyrosine kinase 4	Human,Rhesus	HEK293 Cells
	ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His) thymic stromal lymphopoietin	Human	HEK293 Cells
	TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His) D1S166E,tumor necrosis factor receptor sup...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-00853	IL-1RA Protein, Human, Recombinant DIRA,IL1RA,interleukin 1 receptor antagoni...	Human	E. coli
	IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His) W282,W264,CEA,CD66D,CGM1,MGC11987...	Human	HEK293 Cells
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-02245	SNAP-25 Protein, Human, Recombinant (His) synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ	Human	E. coli
	Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-00203	LOXL2 Protein, Mouse, Recombinant (His) 1110004B06Rik,4930526G1<...	Mouse	HEK293 Cells
	Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-01281	ACVR2B Protein, Mouse, Recombinant (His) ActRIIB,activin A receptor, type IIB,4930516B21...	Mouse	HEK293 Cells
	ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-01851	CD73 Protein, Human, Recombinant (His) eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...	Human	HEK293 Cells
	CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-02525	RGMA Protein, Human, Recombinant (His) repulsive guidance molecule family member a,RGM	Human	HEK293 Cells
	RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-03967	BTN3A3 Protein, Human, Recombinant (His) BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3	Human	HEK293 Cells
	BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-05208	PD-L1 Protein, Human, Recombinant CD274 molecule,PDCD1L1,PD-L1,PDL<...	Human	HEK293 Cells
	PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-00978	Progranulin Protein, Human, Recombinant (His) PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...	Human	HEK293 Cells
	Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-03407	NQO1 Protein, Human, Recombinant (His) NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...	Human	E. coli
	NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-01258	IL-13RA1 Protein, Human, Recombinant (His) NR4,interleukin 13 receptor, alpha 1,CD2	Human	HEK293 Cells
	IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-03531	PSGL-1/CD162 Protein, Human, Recombinant (His) selectin P ligand,PSGL-1,PSGL1,CD1	Human	HEK293 Cells
	PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
TMPY-01883	EPOR Protein, Human, Recombinant (His) erythropoietin receptor,EPO-R	Human	HEK293 Cells
	EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P19235-1.
TMPY-01862	IL-4 Protein, Human, Recombinant Interleukin-4,IL-4,BCGF1,白细胞介素,interleukin 4,BSF	Human	E. coli
	IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-06418	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) R-spondin 2,CRISTIN2	Human	HEK293 Cells
	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-04333	LRRC15 Protein, Human, Recombinant (hFc) leucine rich repeat containing 15,LIB	Human	HEK293 Cells
	LRRC15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.5 kDa and the accession number is Q8TF66-1.
TMPY-02033	CD44 Protein, Human, Recombinant (His) CD44 molecule (Indian blood group),IN,MC56,HUTCH-I,MIC4,CDW4...	Human	HEK293 Cells
	CD44 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is P16070-1.
TMPY-04939	LAG-3 Protein, Human, Recombinant LAG-3,lymphocyte-activation gene 3,CD223	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04104	LIF Protein, Human, Recombinant CDF,DIA,白血病抑制因子,MLPLI,Leukemia Inhibitory Factor,HILDA	Human	HEK293 Cells
	LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-00861	IL-33 Protein, Human, Recombinant IL1F11,C9orf26,NFEHEV,NF-HEV,DVS2...	Human	E. coli
	IL-33 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is O95760-1.
TMPY-06873	FLT3 Ligand Protein, Human, Recombinant FLT3LG,fms related tyrosine kinase 3 ligand,FLT3L,FL	Human	E. coli
	FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-01185	DR5/TRAIL R2 Protein, Human, Recombinant (His) KILLER,TRICK2A,TRICK2,DR5,TRICKB,tumor necrosis factor recep...	Human	HEK293 Cells
	DR5/TRAIL R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O14763-1.
TMPY-01938	CD98 Protein, Human, Recombinant (His) 4T2HC,4F2,CD98HC,NACAE,MDU1,4F2HC,CD98,solute carri...	Human	HEK293 Cells
	CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1.
TMPY-01137	HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) erb-b2 receptor tyrosine kinase 2,NEU,ENVW,HERV-7q,HERV7Q,HE...	Human	HEK293 Cells
	HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is P04626-1.
TMPY-04826	LILRB5/CD85c Protein, Human, Recombinant (His) leukocyte immunoglobulin like receptor B5,LIR8,LIR-8,CD85C	Human	HEK293 Cells
	A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making this variant a potential candidate for susceptibility to muscle-related symptoms. LILRB5/CD85c Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weig...
TMPY-01744	ACVR2A Protein, Human, Recombinant (His) activin A receptor, type IIA,ACVR2,ACTRII	Human	HEK293 Cells
	ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1.
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重组蛋白

CD166/ALCAM Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01031

Species: Mouse

Expression System: HEK293 Cells

CD166/ALCAM Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01153

Species: Mouse

Expression System: HEK293 Cells

GPC1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01368

Species: Mouse

Expression System: HEK293 Cells

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04451

Species: Human

Expression System: Baculovirus Insect Cells

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03878

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-02501

Species: Human

Expression System: HEK293 Cells

CD82 Protein, Human, Recombinant (His)

Cat.No: TMPY-02030

Species: Human

Expression System: HEK293 Cells

SIGIRR Protein, Human, Recombinant (His)

Cat.No: TMPY-01894

Species: Human

Expression System: HEK293 Cells

FLT3 Protein, Human, Recombinant (T227M, His)

Cat.No: TMPY-01247

Species: Human

Expression System: HEK293 Cells

Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

Cat.No: TMPY-02779

Species: Human

Expression System: Baculovirus Insect Cells

HGF Protein, Mouse, Recombinant

Cat.No: TMPY-03290

Species: Mouse

Expression System: HEK293 Cells

TIGIT Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04970

Species: Human

Expression System: HEK293 Cells

R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01147

Species: Human

Expression System: HEK293 Cells

PD-L2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04346

Species: Human

Expression System: HEK293 Cells

VCAM-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00947

Species: Human

Expression System: HEK293 Cells

CD19 Protein, Human, Recombinant (His)

Cat.No: TMPY-01949

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04165

Species: Human

Expression System: HEK293 Cells

IgG1 Fc Protein, Human, Recombinant (C103S)

Cat.No: TMPY-00820

Species: Human

Expression System: HEK293 Cells

Insulin Receptor Protein, Human, Recombinant (long isoform, His)

Cat.No: TMPY-01146

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (His)

Cat.No: TMPY-04348

Species: Human

Expression System: HEK293 Cells

ErbB4 Protein, Human, Rhesus, Recombinant (His)

Cat.No: TMPY-02813

Species: Human,Rhesus

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (R127A & R130S, His)

Cat.No: TMPY-05220

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01827

Species: Human

Expression System: HEK293 Cells

IL-1RA Protein, Human, Recombinant

Cat.No: TMPY-00853

Species: Human

Expression System: E. coli

CEACAM3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01850

Species: Human

Expression System: HEK293 Cells

SNAP-25 Protein, Human, Recombinant (His)

Cat.No: TMPY-02245

Species: Human

Expression System: E. coli

LOXL2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00203

Species: Mouse

Expression System: HEK293 Cells

ACVR2B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01281

Species: Mouse

Expression System: HEK293 Cells

CD73 Protein, Human, Recombinant (His)

Cat.No: TMPY-01851

Species: Human

Expression System: HEK293 Cells

RGMA Protein, Human, Recombinant (His)

Cat.No: TMPY-02525

Species: Human

Expression System: HEK293 Cells

BTN3A3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03967

Species: Human

Expression System: HEK293 Cells

PD-L1 Protein, Human, Recombinant

Cat.No: TMPY-05208

Species: Human

Expression System: HEK293 Cells

Progranulin Protein, Human, Recombinant (His)

Cat.No: TMPY-00978

Species: Human

Expression System: HEK293 Cells

NQO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03407

Species: Human

Expression System: E. coli

IL-13RA1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01258

Species: Human

Expression System: HEK293 Cells

PSGL-1/CD162 Protein, Human, Recombinant (His)

Cat.No: TMPY-03531

Species: Human

Expression System: HEK293 Cells

EPOR Protein, Human, Recombinant (His)

Cat.No: TMPY-01883

Species: Human

Expression System: HEK293 Cells

IL-4 Protein, Human, Recombinant

Cat.No: TMPY-01862

Species: Human

Expression System: E. coli

R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06418

Species: Human

Expression System: HEK293 Cells

LRRC15 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04333

Species: Human

Expression System: HEK293 Cells

CD44 Protein, Human, Recombinant (His)

Cat.No: TMPY-02033

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant

Cat.No: TMPY-04939

Species: Human

Expression System: HEK293 Cells

LIF Protein, Human, Recombinant

Cat.No: TMPY-04104

Species: Human

Expression System: HEK293 Cells

IL-33 Protein, Human, Recombinant

Cat.No: TMPY-00861

Species: Human

Expression System: E. coli

FLT3 Ligand Protein, Human, Recombinant

Cat.No: TMPY-06873

Species: Human

Expression System: E. coli

DR5/TRAIL R2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01185

Species: Human

Expression System: HEK293 Cells

CD98 Protein, Human, Recombinant (His)

Cat.No: TMPY-01938

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)

Cat.No: TMPY-01137

Species: Human

Expression System: HEK293 Cells

LILRB5/CD85c Protein, Human, Recombinant (His)

Cat.No: TMPY-04826

Species: Human

Expression System: HEK293 Cells

ACVR2A Protein, Human, Recombinant (His)

Cat.No: TMPY-01744

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
TMID-0120	Valproic Acid-d15
	Valproic Acid-d15 是 Valproic Acid 的氘代化合物。Valproic Acid 的 CAS 号为 99-66-1。Valproic acid是一种 HDAC 抑制剂，可抑制HDAC1的活性，同时可诱导HDAC2的降解。它激活Notch1信号并抑制小细胞肺癌细胞的增殖。它可研究癫痫、双相情感障碍和偏头痛等。
TMIJ-0163	Valproic Acid-d4
	Valproic Acid-d4 是 Valproic Acid 的氘代化合物。Valproic Acid 的 CAS 号为 99-66-1。Valproic acid是一种 HDAC 抑制剂，可抑制HDAC1的活性，同时可诱导HDAC2的降解。它激活Notch1信号并抑制小细胞肺癌细胞的增殖。它可研究癫痫、双相情感障碍和偏头痛等。
TMIJ-0431	2-(Propyl-3,3,3-d3)pentanoic-5,5,5-d3 Acid
	2-(Propyl-3,3,3-d3)pentanoic-5,5,5-d3 Acid 是 2-pentanoic Acid 的氘代化合物。2-pentanoic Acid 的 CAS 号为 99-66-1。Valproic acid是一种 HDAC 抑制剂，可抑制HDAC1的活性，同时可诱导HDAC2的降解。它激活Notch1信号并抑制小细胞肺癌细胞的增殖。它可研究癫痫、双相情感障碍和偏头痛等。

同位素标记化合物

Valproic Acid-d15

Cat.No: TMID-0120

Valproic Acid-d4

Cat.No: TMIJ-0163

2-(Propyl-3,3,3-d3)pentanoic-5,5,5-d3 Acid

Cat.No: TMIJ-0431

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