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Search Results for " sars cov-2 "

Targets Recommended: SARS-CoV

328

抑制剂 & 化合物

21

天然产物

1

化合物库

737

重组蛋白

8

同位素标记化合物

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Cat. No.	Product Name
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；

化合物库

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

Cat. No.	Product Name	Target	Signaling Pathways
T79455	SARS-CoV-2 Mpro-IN-9 SARS-CoV-2 Mpro IN 9,SARS-CoV-2 Mpro-IN 9	SARS-CoV	Microbiology/Virology
	SARS-CoV-2 Mpro-IN-9 (SARS-CoV-2 Mpro IN 9) 是一种高效的 SARS-CoV-2 Mpro 抑制剂，IC50 值为 80 nM。SARS-CoV-2 Mpro-IN-9 具有抗病毒活性，抑制3C样半胱氨酸蛋白酶，可用于研究病毒感染。
T77510	SARS-CoV-2-IN-46	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-46 是一种 SARS-CoV-2 抑制剂。
T77516	SARS-CoV-2-IN-39	Antiviral; SARS-CoV	Immunology/Inflammation; Microbiology/Virology
	SARS-CoV-2-IN-39是一种 SARS-CoV-2 抑制剂，EC50 为 1 μM。 SARS-CoV-2-IN-39 具有抗病毒活性，通过抑制 SKP2 蛋白并稳定 BECN1 来抑制 SARS-CoV-2。
T77652	SARS-CoV-2 3CLpro-IN-20	Antiviral; SARS-CoV	Immunology/Inflammation; Microbiology/Virology
	SARS-CoV-2 3CLpro-IN-20 是一种共价的 SARS-CoV-2 3CLpro 抑制剂(IC50s: 0.43 μM，)。SARS-CoV-2 3CLpro-IN-20 具有潜在的抗病毒活性。
T60538	SARS-CoV-2-IN-14 3',5-Dichlorosalicylanilide	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-14 是一种有效的、可口服的 SARS-CoV-2 抑制剂（IC50 ：0.39 μM），是一种氯硝柳胺类似物。SARS-CoV-2-IN-14在人血浆和肝 S9 酶测定中比氯硝柳胺稳定性更强。SARS-CoV-2-IN-14以口服的方式给药可以提高其生物利用度和半衰期。
T9458	PF-00835231	SARS-CoV	Microbiology/Virology
	PF-00835231 是一种 CoV-2 半胱氨酸 3C 样蛋白酶抑制剂，对 SARS CoV-2 和 SARS CoV-1 3CLpro 的 IC50 分别为 0.27 nM 和 4 nM。它用于抗 SARS-CoV-2/COVID-19 的研究。
T12838	SARS-CoV-IN-2	Others	Others
	SARS-CoV-IN-2 is an effective SARS-CoV replication inhibitor
T40340	SARS-CoV-2-IN-10	Others	Others
	SARS-CoV-2-IN-10 is a powerful and non-toxic inhibitor of SARS-CoV-2 3CL protease, with IC50 and EC50 values of 0.13 nM and 1.03 nM, respectively. The SARS-CoV-2 3C-like protease (3CLpro) is a critical enzyme for viral replication and serves as an ideal target for intervention. By targeting the SARS-CoV-2 3CL protease, SARS-CoV-2-IN-10 has the potential to facilitate the development of effective antiviral drugs specific to SARS-CoV-2.
T12836	SARS-CoV-2-IN-1	Others	Others
	SARS-CoV-2-IN-1 is a potent inhibitor of Mpro(SARS-CoV-2 Mpro, SARS-CoV Mpro and MERS-CoV Mpro with IC50s of 0.67, 0.90 and 0.58 μM, respectively).
T40207	SARS-CoV-2-IN-7	Others	Others
	SARS-CoV-2-IN-7 demonstrates potent inhibition of viral replication in SARS-CoV-2-infected Vero E6 cells with an IC50 value of 844 nM.
T38942	SARS-CoV-2-IN-9	Others	Others
	SARS-CoV-2-IN-9 is an inhibitor binding to subsites S1 and S2 in SARS-CoV-2 main protease.
T40341	SARS-CoV-2-IN-11	Others	Others
	SARS-CoV-2-IN-11 is a highly potent and non-toxic inhibitor of the 3C-like protease (3CLpro) of SARS-CoV-2, demonstrating IC50 and EC50 values of 0.17 nM and 1.45 nM, respectively. This compound targets the essential viral replication enzyme, 3CLpro, making it an attractive candidate for intervention strategies. SARS-CoV-2-IN-11 holds significant promise in the development of specific antivirals against SARS-CoV-2.
T36654	Anti-SARS-CoV-2 Spike mAb (CR3022) Anti-SARS-CoV-2 Spike mAb (CR3022)
	Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets the S1 domain of the Spike protein in both SARS-CoV and SARS-CoV-2.
T69535	GRL-0820 SARS-CoV-2-IN-6	SARS-CoV	Microbiology/Virology
	GRL-0820 (SARS-CoV-2-IN-6) 是一种高效的 SARS-CoV-2 3CLpro 抑制剂，可用于研究新型冠状病毒感染。
T1817	GNF-2 GNF2	SARS-CoV; Bcr-Abl	Angiogenesis; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	GNF-2 是一种高选择性的非 ATP 竞争性 Bcr-Abl 抑制剂。它抑制 Ba/F3.p210 增殖，IC50为 138 nM。
T12502	PLpro inhibitor 5-(乙酰氨基)-2-甲基-N-[(1R)-1-(1-萘基)乙基]苯甲酰胺	SARS-CoV	Microbiology/Virology
	PLpro inhibitor 是一种木瓜蛋白酶抑制剂，IC50为 2.6 µM，能抑制 SARS-CoV-2 PLpro。
T2486	IOWH-032 IOWH032,IOWH 032	CFTR; Autophagy	Autophagy; Membrane transporter/Ion channel
	IOWH-032 (IOWH032) 是一种合成 CFTR 抑制剂，可用于研究治疗霍乱、腹泻和分泌性腹泻，在T84和CHO-CFTR 细胞实验中IC50为1.01 uM。
T9287	Hydroxychloroquine 2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol,羟氯喹	SARS-CoV; TLR; Parasite; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology
	Hydroxychloroquine (2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol) 是一种合成抗疟疾剂，有效抑制SARS-CoV-2感染，也抑制 Toll 样受体 7/9 信号传导。
T3089	6-Thioguanine 6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine,6-硫代鸟嘌呤	Apoptosis; DNA Methyltransferase; SARS-CoV; Endogenous Metabolite; DUB; Autophagy	Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Ubiquitination
	6-Thioguanine (2-Amino-6-purinethiol) 是一种抗白血病和免疫抑制剂，是 SARS 和 MERS 冠状病毒木瓜样蛋白酶抑制剂，也抑制 USP2的活性，IC50值分别为 25 μM 和 40 μM。
T60919	SARS-CoV-2-IN-13	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-13 (compound 6) 是氯硝柳胺的类似物。在人血浆和肝S9酶测定中，SARS-CoV-2-IN-13 比氯硝柳胺更稳定。SARS-CoV-2-IN-13 口服给药时可以提高生物利用度和半衰期。SARS-CoV-2-IN-13 是SARS-CoV-2的有效抑制剂，IC50值为 0.057 μM。
T78961	SARS-CoV-2-IN-38	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-38是一种可口服的 SARS-CoV-2抑制剂，具有潜在的抗病毒活性，可用于研究 SARS 病毒感染。
T63098	SARS-CoV-2 Mpro-IN-2	SARS-CoV	Microbiology/Virology
	SARS-CoV-2 Mpro-IN-2 是一种选择性的SARS-CoV-2M pro抑制剂，IC50 值为 0.40 μM。SARS-CoV-2 Mpro-IN-2 具有良好的抗病毒活性，可用于研究 COVID-19。
T6833	Favipiravir T-705,6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide,法匹拉韦,法维拉韦	Others; SARS-CoV; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Favipiravir (T-705) 是一种有效且选择性的 RNA 依赖性 RNA 聚合酶抑制剂，用于治疗流感病毒感染。
T15781	LP-935509	Serine/threonin kinase; AAK1 (AP2 associated kinase 1)	Cell Cycle/Checkpoint; Metabolism; Neuroscience
	LP-935509 是一种选择性的、具有脑渗透的、小分子的衔接蛋白-2 相关激酶1 (AAK1) ATP 竞争性抑制剂，其 IC50=3.3 nM，Ki=0.9 nM。它是一种 BIKE 的有效抑制剂 (IC50=14 nM) 和中度的 GAK 抑制剂 (IC50=320 nM)。它能够逆转 SNL 手术后的疼痛。
T79659	SARS-CoV-2 3CLpro-IN-16	SARS-CoV	Microbiology/Virology
	SARS-CoV-2 3CLpro-IN-16为一种共价 SARS-CoV-2 3CLpro 抑制剂，抑制 3CLpro 活性，通过与Cys145形成共价键实现其抑制作用。
T62413	SARS-CoV-2 nsp13-IN-1	Antiviral	Immunology/Inflammation
	SARS-CoV-2 nsp13-IN-1 是一种选择性 nsp13(非结构蛋白 13) 抑制剂，具有抗病毒活性，抑制nsp13 ssDNA+ATPase，可用于研究COVID-19病毒感染。
T1406	Amantadine hydrochloride 盐酸金刚烷胺,1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride	Dopamine Receptor; Influenza Virus	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Amantadine hydrochloride (CI-719) 是一种抗病毒药物，用于预防或对症治疗甲型流感和帕金森病。它阻断质子流通过 M2 离子通道，从而阻止病毒 RNA 释放到感染细胞的细胞质中。
T62834	SARS-CoV-2-IN-22	Others	Others
	SARS-CoV-2-IN-22 是一种 SARS-CoV-2 pseudovirus 抑制剂 (IC50: 16.96 μM)。
T60785	SARS-CoV-2-IN-6	Others	Others
	SARS-CoV-2-IN-6 是IC50值为73 nM 的SARS-CoV-2 3CLpro 抑制剂。
T60962	SARS-CoV-2-IN-18	Others	Others
	SARS-CoV-2-IN-18 (Compound 26) 是 SARS-CoV-2 3C-样蛋白酶的有效抑制剂 (IC50 = 45 nM)。
T79243	SARS-CoV-2-IN-43	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-43(Compound 8h)是一种有效的抗病毒剂，能够抑制SARS-CoV-2的复制。
T81207	SARS-CoV-2-IN-64	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-64（compound 9）为鹅去氧胆酸衍生物，对SARS-CoV-2刺突糖蛋白具有显著抑制作用。
T61613	SARS-CoV-2-IN-17	Others	Others
	SARS-CoV-2-IN-17 (Compound 16) is a highly effective inhibitor of SARS-CoV-2 nucleocapsid protein (NPro). It demonstrates potent anti-viral activity, with an EC50 value of 2.18 μM. Furthermore, SARS-CoV-2-IN-17 binds to NPro with a low Kd value of 7.82 μM, highlighting its potency as a NPro ligand [1].
T81209	SARS-CoV-2-IN-62	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-62 (Compound R3b) 为SARS-CoV-2复制抑制剂，细胞毒性较低。在Vero E6细胞和Calu-3细胞中，其抑制病毒复制的EC50值分别为2.97 μM与3.82 μM。
T79570	SARS-CoV-2-IN-55	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-55 (compound 65) 是一种抑制 SARS-CoV-2 的化合物，具有低细胞毒性，IC50 值为 0.3 μM，它通过作用于病毒的刺突蛋白 S 来抑制病毒感染。
T74948	SARS-CoV-2-IN-30	Others	Others
	SARS-CoV-2-IN-30是含有苯环的双臂二磷酸酯分子镊，展现出对SARS-CoV-2的抗病毒效应，其通过抑制SARS-CoV-2活力与病毒尖刺伪粒子转导，具有IC50值分别为0.6μM和6.9μM。此外，SARS-CoV-2-IN-30能导致脂质体膜破坏，其EC50值为6.9μM。
T79356	SARS-CoV-2-IN-57	Sigma receptor	GPCR/G Protein
	SARS-CoV-2-IN-57 (化合物(+)-R-26)是一种针对SARS-CoV-2具有高效抑制活性的化合物，其IC50为80 nM。该化合物对Sigma受体表现出高亲和性，与S1R和S2R的Kis值分别为13.6 nM和14.4 nM。
T63385	SARS-CoV-2 3CLpro-IN-2	Others	Others
	SARS-CoV-2 3CLpro-IN-2 是 3CL 蛋白酶对有效抑制剂，对SARS-CoV-2疾病表现出研究潜力。
T62264	SARS-CoV-2 nsp13-IN-2	Others	Others
	SARS-CoV-2 nsp13-IN-2 (Compound C2) 是一种 SARS-CoV-2 非结构蛋白 13（nsp13）小分子抑制剂，能够作用于 nsp13 ssDNA+ATPase (IC50: 42 μM)。
T79426	SARS-CoV-2-IN-61	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-61（化合物 8i）是SARS-CoV-2 PLpro的抑制剂，其抗病毒活性表现在其IC50值为16 µM。
T80636	SARS-CoV-2-IN-59	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-59（compound E07）为咪唑啉衍生物，其为一种针对SARS-CoV-2的非肽类小分子抑制剂，主要作用于冠状病毒的Mpro。SARS-CoV-2-IN-59于Mpro残基（Met 165, Gln 166,Met165, His 41, Gln 189）处展现出强烈的相互作用。
T78719	SARS-CoV-2-IN-47	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-47（Compound 13）是一种具有针对SARS-CoV-2变体抑制活性的化合物，显示出对Omicron BA.1的IC50值为0.77 μM，以及对Delta病毒株的IC50值为0.93 μM。该化合物可应用于抗病毒研究领域。
T74946	SARS-CoV-2-IN-28	Others	Others
	SARS-CoV-2-IN-28 是具备双臂二磷酸 C7 烷基酯和延长分子镊子特征的化合物。该化合物展现出针对SARS-CoV-2的抗病毒效能，能以0.4 μM 的 IC50 抑制 SARS-CoV-2 活性及 1.0 μM 的 IC50 抑制病毒尖刺伪粒子转导。此外，SARS-CoV-2-IN-28 在 EC50 为 4.4 μM 的条件下导致脂质体膜破坏。
T63292	SARS-CoV-2-IN-24	Others	Others
	SARS-CoV-2-IN-24 是类木瓜蛋白酶 (PLpro) 的有效抑制剂，能够诱导 SARS-COV-2 木瓜蛋白酶样蛋白酶的构象变化，对 SARS-COV-2 复制具有抑制作用，能够用于研究 SARS-CoV-2。
T64184	SARS-CoV-2-IN-8	Others	Others
	SARS-CoV-2-IN-8 是一种 SARS-CoV-2 主要的蛋白酶抑制剂 (IC50: 0.75 μM)。
T72718	SARS-CoV-2-IN-36	Others	Others
	SARS-CoV-2-IN-36 是一种针对SARS-CoV-2 Mpro(SARS-CoV)的有效抑制剂, 其酶测定的IC50值为2.37 μM，Kd值为1.19 μM。在Vero细胞试验中, SARS-CoV-2-IN-36 对UC-1074、RG2674 及NVDBB-2220 SARS-CoV-2变体展现了抗病毒活性。
T79328	SARS-CoV-2-IN-54	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-54（Compound 2）为针对SARS-CoV-2的抑制剂，展现出抗病毒活性。它能在Vero E6细胞中抑制SARS-CoV-2，其IC50值为21.4 μM。
T81203	SARS-CoV-2-IN-68	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-68（compound 6C）是共价SARS-CoV-2 PLpro/Mpro抑制剂，展现出有效抗病毒活性，并与PLpro的锌指结构域发生结合。
T78926	SARS-CoV-2-IN-42	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-42（Compound 8q）是一种有效的SARS-CoV-2复制抑制剂，具有较低的半抑制浓度（EC50: 0.4 μM），且对宿主细胞无明显毒性。
T63694	SARS-CoV-2-IN-33	Others	Others
	SARS-CoV-2-IN-33 是 COVID-19 抑制剂。ARS-CoV-2-IN-3 对 COVID-19 主要蛋白酶 (Mpro) (PDB ID：6LU7) 表现出较好的结合亲和力 (-8.0 Kcal/mole)。SARS-CoV-2-IN-33 对癌细胞表现出较好的抗增殖效果。SSARS-CoV-2-IN-33 能够用于研究癌症和 COVID-19。

化合物

SARS-CoV-2 Mpro-IN-9

Cat.No: T79455

Synonym: SARS-CoV-2 Mpro IN 9,SARS-CoV-2 Mpro-IN 9

Target: SARS-CoV

SARS-CoV-2-IN-46

Cat.No: T77510

Target: SARS-CoV

SARS-CoV-2-IN-39

Cat.No: T77516

Target: Antiviral, SARS-CoV

SARS-CoV-2 3CLpro-IN-20

Cat.No: T77652

Target: Antiviral, SARS-CoV

SARS-CoV-2-IN-14

Cat.No: T60538

Synonym: 3',5-Dichlorosalicylanilide

Target: SARS-CoV

Cat.No: T9458

Target: SARS-CoV

SARS-CoV-IN-2

Cat.No: T12838

Target: Others

SARS-CoV-2-IN-10

Cat.No: T40340

Target: Others

SARS-CoV-2-IN-1

Cat.No: T12836

Target: Others

SARS-CoV-2-IN-7

Cat.No: T40207

Target: Others

SARS-CoV-2-IN-9

Cat.No: T38942

Target: Others

SARS-CoV-2-IN-11

Cat.No: T40341

Target: Others

Anti-SARS-CoV-2 Spike mAb (CR3022)

Cat.No: T36654

Synonym: Anti-SARS-CoV-2 Spike mAb (CR3022)

Cat.No: T69535

Synonym: SARS-CoV-2-IN-6

Target: SARS-CoV

Cat.No: T1817

Synonym: GNF2

Target: SARS-CoV, Bcr-Abl

PLpro inhibitor

Cat.No: T12502

Synonym: 5-(乙酰氨基)-2-甲基-N-[(1R)-1-(1-萘基)乙基]苯甲酰胺

Target: SARS-CoV

Cat.No: T2486

Synonym: IOWH032,IOWH 032

Target: CFTR, Autophagy

Hydroxychloroquine

Cat.No: T9287

Synonym: 2-[[4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino]ethanol,羟氯喹

Target: SARS-CoV, TLR, Parasite, Autophagy

Cat.No: T3089

Synonym: 6-TG,2-Amino-6-purinethiol,2-Amino-6-mercaptopurine,Thioguanine,6-硫代鸟嘌呤

Target: Apoptosis, DNA Methyltransferase, SARS-CoV, Endogenous Metabolite, DUB, Autophagy

SARS-CoV-2-IN-13

Cat.No: T60919

Target: SARS-CoV

SARS-CoV-2-IN-38

Cat.No: T78961

Target: SARS-CoV

SARS-CoV-2 Mpro-IN-2

Cat.No: T63098

Target: SARS-CoV

Cat.No: T6833

Synonym: T-705,6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide,法匹拉韦,法维拉韦

Target: Others, SARS-CoV, Influenza Virus, DNA/RNA Synthesis

Cat.No: T15781

Target: Serine/threonin kinase, AAK1 (AP2 associated kinase 1)

SARS-CoV-2 3CLpro-IN-16

Cat.No: T79659

Target: SARS-CoV

SARS-CoV-2 nsp13-IN-1

Cat.No: T62413

Target: Antiviral

Amantadine hydrochloride

Cat.No: T1406

Synonym: 盐酸金刚烷胺,1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride

Target: Dopamine Receptor, Influenza Virus

SARS-CoV-2-IN-22

Cat.No: T62834

Target: Others

SARS-CoV-2-IN-6

Cat.No: T60785

Target: Others

SARS-CoV-2-IN-18

Cat.No: T60962

Target: Others

SARS-CoV-2-IN-43

Cat.No: T79243

Target: SARS-CoV

SARS-CoV-2-IN-64

Cat.No: T81207

Target: SARS-CoV

SARS-CoV-2-IN-17

Cat.No: T61613

Target: Others

SARS-CoV-2-IN-62

Cat.No: T81209

Target: SARS-CoV

SARS-CoV-2-IN-55

Cat.No: T79570

Target: SARS-CoV

SARS-CoV-2-IN-30

Cat.No: T74948

Target: Others

SARS-CoV-2-IN-57

Cat.No: T79356

Target: Sigma receptor

SARS-CoV-2 3CLpro-IN-2

Cat.No: T63385

Target: Others

SARS-CoV-2 nsp13-IN-2

Cat.No: T62264

Target: Others

SARS-CoV-2-IN-61

Cat.No: T79426

Target: SARS-CoV

SARS-CoV-2-IN-59

Cat.No: T80636

Target: SARS-CoV

SARS-CoV-2-IN-47

Cat.No: T78719

Target: SARS-CoV

SARS-CoV-2-IN-28

Cat.No: T74946

Target: Others

SARS-CoV-2-IN-24

Cat.No: T63292

Target: Others

SARS-CoV-2-IN-8

Cat.No: T64184

Target: Others

SARS-CoV-2-IN-36

Cat.No: T72718

Target: Others

SARS-CoV-2-IN-54

Cat.No: T79328

Target: SARS-CoV

SARS-CoV-2-IN-68

Cat.No: T81203

Target: SARS-CoV

SARS-CoV-2-IN-42

Cat.No: T78926

Target: SARS-CoV

SARS-CoV-2-IN-33

Cat.No: T63694

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T7991	2-Hydroxycinnamic acid 邻羟基肉桂酸(邻香豆酸),(E)-3-(2-羟基苯基)丙烯酸	Others; SARS-CoV; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	2-Hydroxycinnamic acid 是从肉桂的甲醇提取物中分离出的一种天然产物，具有光氧化活性。它对HIV/SARS-CoV S 假病毒的感染具有抑制作用，IC50为 0.3 mM。
T7060	Amantadine 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine	Others	Others
	Amantadine (1-Aminoadamantane) 是抗病毒药物，也是是 NMDA 型谷氨酸受体的弱拮抗剂，能促进高多巴胺的释放，并阻断多巴胺的再摄取。
T72581	SARS-CoV MPro-IN-2	Others	Others
	SARS-CoVMPro-IN-2 是一种有效的SARS-CoV-2 Mpro 抑制剂，IC50sub>值为 72.07 nM。病毒的主要蛋白酶 Mpro 作为加工病毒多蛋白的主要酶，有助于 SARS-CoV-2 在宿主细胞中的复制和转录，并已被定性为药物发现的有吸引力的靶点。SARS-CoVMPro-IN-2 具有研究 COVID-19 的潜力。
T9715	Aplidine	SARS-CoV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Aplidine 是有效的eEF1A2(KD=80 nM) 靶向的抗癌药物。Aplidine 具有抗病毒活性，抑制SARS-CoV-2的 IC90为 0.88 nM。Aplidine 在多发性骨髓瘤，晚期癌症及 COVID-19 领域有研究的价值。
T8689	Chloroquine CQ,氯喹	SARS-CoV; TLR; HIV Protease; Antibiotic; Parasite; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Chloroquine 是一种 Toll 样受体抑制剂，可以抑制自噬。Chloroquine 具有抗疟疾和抗炎活性，广泛用于治疗疟疾和类风湿性关节炎。Chloroquine 还具有抗 SARS-CoV-2 (COVID-19) 活性、抗 HIV-1 活性。
T3S1447	Arteannuin B	SARS-CoV; Ferroptosis	Apoptosis; Microbiology/Virology
	Arteannuin B 与青蒿素共同存在，有强效抗疟活性，具有抗 SARS-CoV-2 的活性，EC50为 10.28 μM。
TN3651	Cichoriin	Others	Others
	Cichoriin 对SARS-CoV-2有明显活性，是治疗重症COVID-19的潜在候选物质。
T2869	Emodin Frangula emodin,大黄素	SARS-CoV; Casein Kinase; Autophagy	Autophagy; Metabolism; Microbiology/Virology; Stem Cells
	Emodin (Frangula emodin) 是蒽醌衍生物，有抗SARS-CoV 作用。它阻断 SARS 冠状病毒刺突蛋白和血管紧张素转化酶 2 的相互作用。它抑制酪蛋白激酶 2 ，具有抗炎和抗癌作用。它可改善饮食诱导的肥胖小鼠的代谢紊乱。
T2563	Acetyl-L-carnitine hydrochloride Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,乙酰-L-肉(毒)碱盐酸盐,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) 是一种由内源性左旋肉碱的乙酰化形式的盐酸盐组成的营养补充剂，具有潜在的神经保护、认知增强、抗抑郁和免疫调节活性。还可缓解化疗、糖尿病或其他疾病引起的周围神经病变。此外，乙酰左旋肉碱可能通过增加T淋巴细胞成熟来调节免疫反应，并可能下调促炎细胞因子对病毒(如SARS-CoV-2)的反应。它还可能破坏ACE2信号通路并抑制活性氧(ROS)的产生。
TQ0180	Chebulagic acid	SARS-CoV; Influenza Virus; Lipoxygenase; COX	Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
	Chebulagic acid 是从 Terminalia chebula Retz 中分离出来的一种 COX-LOX 双重抑制剂，有抗炎和抗感染作用。它抑制 SARS-CoV-2病毒的复制，EC50值为 9.76 μM。它还是 M2(S31N)抑制剂和抗流感病毒剂。
T0194	Chloroquine phosphate Chloroquine diphosphate,Aralen phosphate,磷酸氯喹,Chingamin phosphate	SARS-CoV; TLR; HIV Protease; Antibiotic; Parasite; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Chloroquine phosphate (Aralen phosphate) 是广泛用于疟疾和类风湿性关节炎的抗疟疾和抗炎剂。它是autophagy 和toll-like receptors 抑制剂，有效抑制SARS-CoV-2(COVID-19) 感染 (EC50=1.13 μM)。
T21883	Gedunin	HSP	Cytoskeletal Signaling; Metabolism
	Gedunin 是从印楝种子中提取的一种重要柠檬苦素，具有抗癌、抗病毒、抗炎和杀虫活性。它可阻断 SARS-CoV-2 病毒进入人宿主细胞，用于 COVID-19 研究。它是Hsp90抑制剂，诱导 Hsp90 依赖的蛋白降解，抑制卵巢癌细胞增殖。
T6670	Silymarin Silybin B,水飞蓟素	SARS-CoV	Microbiology/Virology
	Silymarin (Silybin B) 是一种多酚类黄酮，是从水飞蓟或水飞蓟的种子中提取的一种 SARS-CoV-2 主蛋白酶抑制剂。它可降低肿瘤细胞的增殖，血管生成以及胰岛素抵抗，用于预防和治疗肝脏疾病，有潜力研究 COVID-19 。
TN2302	Viscidulin III Ganhuangenin	Glucosidase	Metabolism
	Viscidulin III (Ganhuangenin) 存在于黄芩中，可作为α-葡萄糖苷酶抑制剂。
T79947	10-Hydroxyaloin A	SARS-CoV	Microbiology/Virology
	10-Hydroxyaloin A有效抑制SARS-CoV-2，与SARS-CoV-2 Mpro活性位点显著结合。
T73561	NK007	Others	Others
	NK007 是一种新型抗 SARS-CoV-2 药物，其 EC50值为 30 nM。
T80010	(25S)-Antcin B	SARS-CoV	Microbiology/Virology
	Antcin-B是3CLPro的高亲和力有效抑制剂，可用于SARS-CoV-2的研究。
T73900	(±)-Alliin	Others	Others
	(±)-Alliin 是大蒜的主要活性成分。(±)-Alliin 被认为是SARS-CoV-2 (Mpro)的虚拟抑制剂。
T75533	Dihydromaniwamycin E	Others	Others
	Dihydromaniwamycin E 是一种热休克代谢物，对influenza 和SARS-CoV-2病毒具有抗病毒活性。
T75534	Maniwamycin E	Others	Others
	Maniwamycin E，一种耐热链霉菌培养提取物中分离得到的马尼瓦霉素衍生物，展示了对SARS-CoV-2和H1N1流感病毒的抗病毒活性。
T75540	Ipomoeassin F	Others	Others
	Ipomoeassin F 是一种高效且具有选择性的内质网(ER)蛋白转位抑制剂，它通过作用于ER膜上的Sec61复合物（Sec61α）的成孔亚基来实现其功能。此化合物能特异性抑制SARS-CoV-2蛋白在ER膜上的转位，同时阻碍分泌蛋白和I型跨膜蛋白（TMP）的ER转运，但对III型TMP的转运不产生影响。

天然产物

2-Hydroxycinnamic acid

Cat.No: T7991

Synonym: 邻羟基肉桂酸(邻香豆酸),(E)-3-(2-羟基苯基)丙烯酸

Target: Others, SARS-CoV, HIV Protease

Cat.No: T7060

Synonym: 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine

Target: Others

SARS-CoV MPro-IN-2

Cat.No: T72581

Target: Others

Cat.No: T9715

Target: SARS-CoV, DNA/RNA Synthesis

Cat.No: T8689

Synonym: CQ,氯喹

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

Cat.No: T3S1447

Target: SARS-CoV, Ferroptosis

Cat.No: TN3651

Target: Others

Cat.No: T2869

Synonym: Frangula emodin,大黄素

Target: SARS-CoV, Casein Kinase, Autophagy

Acetyl-L-carnitine hydrochloride

Cat.No: T2563

Synonym: Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,乙酰-L-肉(毒)碱盐酸盐,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride

Target: Others, Endogenous Metabolite

Chebulagic acid

Cat.No: TQ0180

Target: SARS-CoV, Influenza Virus, Lipoxygenase, COX

Chloroquine phosphate

Cat.No: T0194

Synonym: Chloroquine diphosphate,Aralen phosphate,磷酸氯喹,Chingamin phosphate

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

Cat.No: T21883

Target: HSP

Cat.No: T6670

Synonym: Silybin B,水飞蓟素

Target: SARS-CoV

Cat.No: TN2302

Synonym: Ganhuangenin

Target: Glucosidase

10-Hydroxyaloin A

Cat.No: T79947

Target: SARS-CoV

Cat.No: T73561

Target: Others

Cat.No: T80010

Target: SARS-CoV

Cat.No: T73900

Target: Others

Dihydromaniwamycin E

Cat.No: T75533

Target: Others

Cat.No: T75534

Target: Others

Cat.No: T75540

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01426	SARS-CoV-2 NSP2 Protein (His) SARS-CoV 2 nsp2,SARS...	SARS-CoV-2	E. coli
	The positive-stranded RNA genome of the coronaviruses is translated from ORF1 to yield polyproteins that are proteolytically processed into intermediate and mature nonstructural proteins (nsps). SARS-CoV 2 polyproteins incorporate 16 protein domains (nsps). The putative non-structural protein 2 (nsp2) of SARS-CoV plays an important role in viral transcription and replication, and is an attractive target for anti-SARS drug development.
TMPJ-01450	SARS-CoV-2 Helicase Protein (His & MBP) SARS-CoV 2 nsp13,SARS-	SARS-CoV-2	E. coli
	The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity, using the energy of nucleotide hydrolysis. A basic biochemical characterization of nsp13 demonstrated that it can unwind both doublestranded DNA and RNA in a 5’-3’ direction, and it can hydrolyze all deoxyribonucleotide and ribonucleotide triphosphates. Helicases are motor proteins that utilize the energy derived from nucleotide hydrolysisto unwind double-stranded nu...
TMPJ-01425	SARS-CoV-2 NSP1 Protein (His) SARS-CoV 2 nsp1,SARS-	SARS-CoV-2	E. coli
	The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close associa...
TMPJ-01428	SARS-CoV-2 NSP8 Protein (His) SARS-CoV 2 nsp8	SARS-CoV-2	E. coli
	Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependen...
TMPJ-01427	SARS-CoV-2 NSP7 Protein (His) SARS-CoV 2 nsp7	SARS-CoV-2	E. coli
	The ∼30kb positive-stranded RNA genome of coronaviruses encodes a replication/transcription machinery that is unusually complex and composed of 16 nonstructural proteins (nsps). The four proteins nsp7 to nsp10, which are conserved among all CoVs but have no functional homologs outside of the Coronaviridae, are translated as part of the viral polyproteins pp1a and pp1ab, and the mature proteins are released by the action of the SARS-CoV protease nsp5. Hexadecamer of nsp7 and nsp8 may possess dsRN...
TMPJ-01429	SARS-CoV-2 Guanine-N7 methyltransferase Protein (His) SARS-CoV 2 nsp14,Guanine-N7 methy...	SARS-CoV-2	E. coli
	The nonstructural protein (nsp) 14 of SARS-CoV 2 was identified as a cap (guanine-N7)-methyltransferase (N7-MTase). Nsp14 of coronaviruses two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity. It may be involved in the proof-reading ability during the viral RNA replication and transcription. GTP, dGTP as well as cap analogs GpppG, GpppA and m7GpppG could be methylated by nsp14.
TMPK-01412	HLA-B15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) SARS-CoV*-2 epitope,MHC	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPK-01416	HLA-B15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,SARS-CoV*-2 epitope	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPY-05679	SARS-CoV-2 Spike RBD Protein (hFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (hFc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 51.8 kDa and the accession number is A0A6G7K2L4.
TMPK-00265	SARS-COV-2 Nucleocapsid Protein (His & Avi), Biotinylated Nucleocapsid,NC,NP	SARS-CoV-2	E. coli
	Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed in the cytoplasm of infected cells. SARS-COV-2 Nucleocapsid Protein (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 48.9 kDa and the accession number is P0DTC9.
TMPY-06078	SARS-CoV-2 envelope(CoV-E) protein Protein (C40A & C43A & C44A, His & MBP)	SARS-CoV-2	E. coli
	SARS-CoV-2 envelope(CoV-E) protein Protein (C40A & C43A & C44A, His & MBP) is expressed in E. coli expression system. The predicted molecular weight is 52.2 kDa and the accession number is YP_009724392.1.
TMPY-06071	SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 108.3 kDa and the accession number is YP_009725307.1.
TMPY-06615	SARS-CoV-2 XBB (Omicron) Spike S1+S2 trimer Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 XBB (Omicron) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 136.26 kDa and the accession number is YP_009724390.1.
TMPY-06626	SARS-COV-2 BQ.1/BQ.1.1 (Omicron) Nucleoprotein/NP Protein (His)	SARS-CoV-2	E. coli
	SARS-COV-2 BQ.1/BQ.1.1 (Omicron) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.36 kDa and the accession number is YP_009724397.2.
TMPY-06416	SARS-CoV-2 NSP8 Protein	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarkably stimulate RdRp activity. The nsp12-nsp7-nsp8 subcomplex is defined as the minimal core component for mediating coronavirus RNA synthesis. SARS-CoV-2 NSP8 Protein is expressed in E. coli expression system. The predicted molecular weight is 22.04 kDa and the accession number is...
TMPY-06009	SARS-CoV-2 NSP7 Protein	SARS-CoV-2	E. coli
	NSP7 is conserved within the coronaviridae. NSP7 is a component of the coronavirus replicase polyprotein to comprise a repilication complex. NSP7 has been shown to interact with NSP10 and NSP1 which indicate that NSP7 has a founction in coronavirus-specific RNA replication mechanisms.
TMPY-06012	SARS-CoV-2 NSP10 Protein	SARS-CoV-2	E. coli
	NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp14 and nsp16 and possibly other subunits of the viral replication complex may be a target for the development of antiviral compounds against pathogenic coronaviruses. SARS-CoV-2 NSP10 Protein is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and ...
TMPY-05820	SARS-CoV-2 NSP3 Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 NSP3 Protein (His) is expressed in E. coli expression system. The predicted molecular weight is 19.87 kDa and the accession number is YP_009725299.1.
TMPY-05664	SARS-CoV-2 Nucleocapsid Protein (His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Nucleocapsid Protein (His) is expressed in Baculovirus insect cells. The predicted molecular weight is 47.08 kDa and the accession number is P0DTC9.
TMPY-06086	SARS-CoV-2 Helicase Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Helicase Protein (His) is expressed in E. coli expression system. The predicted molecular weight is 67.8 kDa and the accession number is YP_009725308.1.
TMPY-06011	SARS-CoV-2 NSP10 Protein (His)	SARS-CoV-2	E. coli
	NSP10 is a major regulator of coronavirus replicase function. NSP10 contains two zinc fingers and binds and stimulates both NSP14 and NSP16 activities. Researchers has found that the nsp10 surface that interacts with nsp14 and nsp16 and possibly other subunits of the viral replication complex may be a target for the development of antiviral compounds against pathogenic coronaviruses. SARS-CoV-2 NSP10 Protein (His) is expressed in E. coli expression system. The predicted molecular weight is 15.7 ...
TMPY-05749	SARS-CoV-2 NSP8 Protein (Avi)	SARS-CoV-2	E. coli
	NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarkably stimulate RdRp activity. The nsp12-nsp7-nsp8 subcomplex is defined as the minimal core component for mediating coronavirus RNA synthesis. SARS-CoV-2 NSP8 Protein (Avi) is expressed in E. coli expression system. The predicted molecular weight is 24.17 kDa and the accession num...
TMPY-05695	SARS-CoV-2 Nucleocapsid Protein (His), Biotinylated	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Nucleocapsid Protein (His), Biotinylated is expressed in Baculovirus insect cells. The predicted molecular weight is 47.08 kDa and the accession number is P0DTC9.
TMPY-05712	SARS-CoV-2 NSP9 Protein (His & Avi)	SARS-CoV-2	E. coli
	SARS-CoV-2 NSP9 Protein (His & Avi) is expressed in E. coli expression system. The predicted molecular weight is 15.46 kDa and the accession number is YP_009725305.1.
TMPY-06144	SARS-CoV-2 Nucleocapsid Protein (D377Y, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (D377Y, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.5 kDa and the accession number is P0DTC9.
TMPY-06190	SARS-CoV-2 Nucleocapsid Protein (P199L, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (P199L, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.6 kDa and the accession number is P0DTC9.
TMPY-06113	SARS-CoV-2 Nucleocapsid CTD Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid CTD Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.2 kDa and the accession number is P0DTC9.
TMPY-05681	SARS-CoV-2 Spike RBD Protein (rFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (rFc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.3 kDa and the accession number is A0A6G7K2L4.
TMPY-06098	SARS-CoV-2 Nucleocapsid Protein (I292T, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (I292T, His) is expressed in E. coli expression system. The predicted molecular weight is 46.6 kDa and the accession number is P0DTC9.
TMPY-06123	SARS-CoV-2 Nucleocapsid Protein (P80R, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (P80R, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P0DTC9.
TMPY-06124	SARS-CoV-2 Nucleocapsid Protein (T205I, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (T205I, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.6 kDa and the accession number is P0DTC9.
TMPY-06097	SARS-CoV-2 Nucleocapsid Protein (S194L, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (S194L, His) is expressed in E. coli expression system. The predicted molecular weight is 46.6 kDa and the accession number is P0DTC9.
TMPY-05663	SARS-CoV-2 Spike RBD Protein (mFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (mFc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 51.5 kDa and the accession number is A0A6G7K2L4.
TMPY-05667	SARS-CoV-2 Spike S1 Protein (His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike S1 Protein (His) is expressed in Baculovirus insect cells. The predicted molecular weight is 76.45 kDa and the accession number is A0A6G7K2L4.
TMPY-06189	SARS-CoV-2 Nucleocapsid Protein (A220V, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (A220V, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.6 kDa and the accession number is P0DTC9.
TMPJ-01431	SARS-CoV-2 Papain-Like Protease Protein PLpro,PL-PRO,pp1a,Replicase polyprotein 1a,Papain-like Prote...	SARS-CoV-2	E. coli
	Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro). These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV. PLpro is a cysteine protease located within the non-structural protein 3 (NS3) sect...
TMPY-05660	SARS-CoV-2 Spike S1 Protein (hFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (hFc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 101.7 kDa and the accession number is A0A6G7K2L4.
TMPY-05668	SARS-CoV-2 Spike RBD Protein (His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike RBD Protein (His) is expressed in Baculovirus insect cells. The predicted molecular weight is 26.54 kDa and the accession number is A0A6G7K2L4.
TMPY-06188	SARS-CoV-2 Nucleocapsid Protein (M234L, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (M234L, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.6 kDa and the accession number is P0DTC9.
TMPY-06221	SARS-CoV-2 Nucleocapsid Protein (P67S, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (P67S, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.6 kDa and the accession number is P0DTC9.
TMPY-06217	SARS-CoV-2 Nucleocapsid Protein (S202N, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (S202N, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.6 kDa and the accession number is P0DTC9.
TMPY-06114	SARS-CoV-2 Nucleocapsid NTD Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid NTD Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P0DTC9.
TMPY-06145	SARS-CoV-2 Nucleocapsid Protein (E378Q, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (E378Q, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.5 kDa and the accession number is P0DTC9.
TMPK-00263	SARS-COV-2 Nucleocapsid Protein (His & Avi) NC,Nucleocapsid,NP	SARS-CoV-2	E. coli
	Nucleocapsid protein (N) is the major viral structural component; its main function is to protect and encapsidate the viral RNA forming viral RNP complex. It is encoded by the S segment vRNA and is abundantly expressed in the cytoplasm of infected cells. SARS-COV-2 Nucleocapsid Protein (His & Avi) is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 48.9 kDa and the accession number is P0DTC9.
TMPY-05693	SARS-CoV-2 Methyltransferase/ME Protein (His)	SARS-CoV-2	E. coli
	Coronavirus encodes the 2’-O-MTase (2'O Methyltransferase) that is composed of the catalytic subunit nsp16 and the stimulatory subunit nsp10 and plays an important role in virus genome replication and evasion from innate immunity during viral infection. Nonstructural protein 16 (NSP16) / viral 2'O-methyltransferase (2'O-MTase) is highly conserved. The conserved 2'O-MTase activity is important for CoV pathogenesis and NSP16 is a conserved universal target for rapid live attenuated vaccine design ...
TMPY-05662	SARS-CoV-2 Spike S1 Protein (mFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike S1 Protein (mFc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 101.4 kDa and the accession number is A0A6G7K2L4.
TMPY-06096	SARS-CoV-2 Nucleocapsid Protein (P13L, His)	SARS-CoV-2	E. coli
	SARS-CoV-2 Nucleocapsid Protein (P13L, His) is expressed in E. coli expression system. The predicted molecular weight is 46.6 kDa and the accession number is P0DTC9.
TMPY-05975	SARS-CoV-2 Spike RBD Protein (P521S, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (P521S, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.5 kDa and the accession number is A0A6G7K2L4.
TMPY-06041	SARS-CoV-2 Spike RBD Protein (K458Q, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (K458Q, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.5 kDa and the accession number is A0A6G7K2L4.
TMPY-05990	SARS-CoV-2 Spike RBD Protein (S477I, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (S477I, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
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重组蛋白

SARS-CoV-2 NSP2 Protein (His)

Cat.No: TMPJ-01426

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Helicase Protein (His & MBP)

Cat.No: TMPJ-01450

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 NSP1 Protein (His)

Cat.No: TMPJ-01425

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 NSP8 Protein (His)

Cat.No: TMPJ-01428

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 NSP7 Protein (His)

Cat.No: TMPJ-01427

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Guanine-N7 methyltransferase Protein (His)

Cat.No: TMPJ-01429

Species: SARS-CoV-2

Expression System: E. coli

HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01412

Species: Human

Expression System: HEK293 Cells

HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01416

Species: Human

Expression System: HEK293 Cells

SARS-CoV-2 Spike RBD Protein (hFc)

Cat.No: TMPY-05679

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-COV-2 Nucleocapsid Protein (His & Avi), Biotinylated

Cat.No: TMPK-00265

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 envelope(CoV-E) protein Protein (C40A & C43A & C44A, His & MBP)

Cat.No: TMPY-06078

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His)

Cat.No: TMPY-06071

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 XBB (Omicron) Spike S1+S2 trimer Protein (His)

Cat.No: TMPY-06615

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-COV-2 BQ.1/BQ.1.1 (Omicron) Nucleoprotein/NP Protein (His)

Cat.No: TMPY-06626

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 NSP8 Protein

Cat.No: TMPY-06416

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 NSP7 Protein

Cat.No: TMPY-06009

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 NSP10 Protein

Cat.No: TMPY-06012

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 NSP3 Protein (His)

Cat.No: TMPY-05820

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (His)

Cat.No: TMPY-05664

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Helicase Protein (His)

Cat.No: TMPY-06086

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 NSP10 Protein (His)

Cat.No: TMPY-06011

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 NSP8 Protein (Avi)

Cat.No: TMPY-05749

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (His), Biotinylated

Cat.No: TMPY-05695

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 NSP9 Protein (His & Avi)

Cat.No: TMPY-05712

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (D377Y, His)

Cat.No: TMPY-06144

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (P199L, His)

Cat.No: TMPY-06190

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid CTD Protein (His)

Cat.No: TMPY-06113

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Spike RBD Protein (rFc)

Cat.No: TMPY-05681

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Nucleocapsid Protein (I292T, His)

Cat.No: TMPY-06098

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (P80R, His)

Cat.No: TMPY-06123

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (T205I, His)

Cat.No: TMPY-06124

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (S194L, His)

Cat.No: TMPY-06097

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Spike RBD Protein (mFc)

Cat.No: TMPY-05663

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike S1 Protein (His)

Cat.No: TMPY-05667

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Nucleocapsid Protein (A220V, His)

Cat.No: TMPY-06189

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Papain-Like Protease Protein

Cat.No: TMPJ-01431

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Spike S1 Protein (hFc)

Cat.No: TMPY-05660

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike RBD Protein (His)

Cat.No: TMPY-05668

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

SARS-CoV-2 Nucleocapsid Protein (M234L, His)

Cat.No: TMPY-06188

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (P67S, His)

Cat.No: TMPY-06221

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (S202N, His)

Cat.No: TMPY-06217

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid NTD Protein (His)

Cat.No: TMPY-06114

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Nucleocapsid Protein (E378Q, His)

Cat.No: TMPY-06145

Species: SARS-CoV-2

Expression System: E. coli

SARS-COV-2 Nucleocapsid Protein (His & Avi)

Cat.No: TMPK-00263

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Methyltransferase/ME Protein (His)

Cat.No: TMPY-05693

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Spike S1 Protein (mFc)

Cat.No: TMPY-05662

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Nucleocapsid Protein (P13L, His)

Cat.No: TMPY-06096

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 Spike RBD Protein (P521S, His)

Cat.No: TMPY-05975

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike RBD Protein (K458Q, His)

Cat.No: TMPY-06041

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 Spike RBD Protein (S477I, His)

Cat.No: TMPY-05990

Species: SARS-CoV-2

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T60016	VV116 GS-621763-d1,JT001	SARS-CoV; RSV	Microbiology/Virology
	VV116 (JT001) 是一种针对呼吸道合胞病毒和 SARS-CoV-2 感染的选择性和口服活性核苷抗病毒剂。
TMIH-0394	Nirmatrelvir-d9
	Nirmatrelvir-d9 是 Nirmatrelvir 的氘代化合物。Nirmatrelvir 的 CAS 号为 2628280-40-8。PF-07321332 是一种有效的口服活性SARS-CoV 3CLPRO抑制剂，对 SARS-CoV-2 病毒有针对性，可研究 COVID-19。它是一种胰蛋白酶样蛋白酶抑制剂，可抑制气道上皮钠通道功能。
TMIH-0146	Chloroquine-d5
	Chloroquine-d5 是 Chloroquine 的氘代化合物。Chloroquine 的 CAS 号为 54-05-7。Chloroquine 是一种自噬和 Toll 样受体抑制剂。氯喹是一种抗疟疾和抗炎剂，广泛用于治疗疟疾和类风湿性关节炎。它在体外控制 SARS-CoV-2 (COVID-19) 感染方面非常有效，EC50 为 1.13 μM。
T38297	Ribavirin-13C5 Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...
TMIJ-0076	Ritonavir-13C-d3
	Ritonavir-13C-d3 是 Ritonavir 的 13C 和氘代化合物。Ritonavir 的 CAS 号为 155213-67-5。Ritonavir 是一种 HIV 蛋白酶抑制剂，可研究 HIV 感染和 AIDS 。它也是SARS-CoV 3CLpro的抑制剂，IC50为 1.61 μM。
TMIJ-0339	Bromhexine-d3 HCl
	Bromhexine-d3 HCl 是 Bromhexine HCl 的氘代化合物。Bromhexine HCl 的 CAS 号为 611-75-6。Bromhexine hydrochloride 是TMPRSS2蛋白酶的一种特异性有效抑制剂，IC50为 0.75 μM。它可预防和控制SARS-CoV-2感染。它是一种粘液溶解剂，用于治疗与粘稠或过多粘液相关的呼吸系统疾病。
TMID-0208	Hydroxychloroquine-d5
	Hydroxychloroquine-d5 是 Hydroxychloroquine 的氘代化合物。Hydroxychloroquine 的 CAS 号为 118-42-3。Hydroxychloroquine 是一种合成抗疟疾剂，有效抑制SARS-CoV-2感染，也抑制 Toll 样受体 7/9 信号传导。
TMID-0083	Arbidol-d6 Hydrochloride
	Arbidol-d6 Hydrochloride 是 Arbidol Hydrochloride 的氘代化合物。Arbidol Hydrochloride 的 CAS 号为 131707-23-8。Umifenovir hydrochloride 是一种口服有效的广谱抗病毒药物，对多种包膜和非包膜病毒均有活性。它被用作抗流感病毒剂，可通过阻断病毒与宿主细胞膜的融合来抑制包膜病毒的细胞侵袭。它是一种 SARS-CoV-2 抑制剂，具有抗炎活性。

同位素标记化合物

Cat.No: T60016

Synonym: GS-621763-d1,JT001

Target: SARS-CoV, RSV

Nirmatrelvir-d9

Cat.No: TMIH-0394

Cat.No: TMIH-0146

Cat.No: T38297

Synonym: Ribavirin-13C5

Ritonavir-13C-d3

Cat.No: TMIJ-0076

Bromhexine-d3 HCl

Cat.No: TMIJ-0339

Hydroxychloroquine-d5

Cat.No: TMID-0208

Arbidol-d6 Hydrochloride

Cat.No: TMID-0083

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