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Search Results for " sars cov-1 "

Targets Recommended: SARS-CoV

200

抑制剂 & 化合物

11

天然产物

1

化合物库

1749

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；

化合物库

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

Cat. No.	Product Name	Target	Signaling Pathways
T9614	MERS-CoV-IN-1	SARS-CoV	Microbiology/Virology
	MERS-CoV-IN-1 对冠状病毒的活性具有优异的抑制作用，可用作预防冠状病毒引起疾病的药物组合物。
T9458	PF-00835231	SARS-CoV	Microbiology/Virology
	PF-00835231 是一种 CoV-2 半胱氨酸 3C 样蛋白酶抑制剂，对 SARS CoV-2 和 SARS CoV-1 3CLpro 的 IC50 分别为 0.27 nM 和 4 nM。它用于抗 SARS-CoV-2/COVID-19 的研究。
T12837	SARS-CoV-IN-1	Others	Others
	SARS-CoV-IN-1 is an effective SARS-CoV replication inhibitor(EC50 of 4.9 μM in Vero cells).
T7872	Monolaurin	Others	Others
	Monolaurin 是椰子油中的一种表面活性剂和乳化剂。它抑制葡萄球菌、链球菌、加德纳菌、念珠菌和嗜血杆菌的生长，并减少促炎细胞因子的产生。
T37174	SARS-CoV MPro-IN-1	Others	Others
	MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.04 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50= 0.72 μM). MProinhibitor 11b also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 μM. 1.Dai, W., Zhang, B., Jiang, X.-M., et al.Structure-based design of antiviral drug candidates targeting the SARS-C...
T12836	SARS-CoV-2-IN-1	Others	Others
	SARS-CoV-2-IN-1 is a potent inhibitor of Mpro(SARS-CoV-2 Mpro, SARS-CoV Mpro and MERS-CoV Mpro with IC50s of 0.67, 0.90 and 0.58 μM, respectively).
T9618	HeE1-2Tyr	SARS-CoV	Microbiology/Virology
	HeE1-2Tyr 是一种pyridobenzothiazole，抑制黄病毒 RNA 依赖性 RNA 聚合酶。HeE1-2Tyr 在体外对Dengue, West Nile 和 SARS-CoV-2 RdRps 有显著的抑制活性(IC50为 27.6 µM) 。
T12502	PLpro inhibitor 5-(乙酰氨基)-2-甲基-N-[(1R)-1-(1-萘基)乙基]苯甲酰胺	SARS-CoV	Microbiology/Virology
	PLpro inhibitor 是一种木瓜蛋白酶抑制剂，IC50为 2.6 µM，能抑制 SARS-CoV-2 PLpro。
T15781	LP-935509	Serine/threonin kinase; AAK1 (AP2 associated kinase 1)	Cell Cycle/Checkpoint; Metabolism; Neuroscience
	LP-935509 是一种选择性的、具有脑渗透的、小分子的衔接蛋白-2 相关激酶1 (AAK1) ATP 竞争性抑制剂，其 IC50=3.3 nM，Ki=0.9 nM。它是一种 BIKE 的有效抑制剂 (IC50=14 nM) 和中度的 GAK 抑制剂 (IC50=320 nM)。它能够逆转 SNL 手术后的疼痛。
T62413	SARS-CoV-2 nsp13-IN-1	Antiviral	Immunology/Inflammation
	SARS-CoV-2 nsp13-IN-1 是一种选择性 nsp13(非结构蛋白 13) 抑制剂，具有抗病毒活性，抑制nsp13 ssDNA+ATPase，可用于研究COVID-19病毒感染。
T0100L	Atazanavir Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632	P450; SARS-CoV; HIV Protease; P-gp	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Atazanavir (BMS-232632) 是一种高选择性的HIV-1蛋白酶抑制剂，可研究艾滋病毒感染。它也是SARS-CoV 3CLpro 的抑制剂，IC50为 3.49 μM。它是CYP3A4的底物和抑制剂，也是P-糖蛋白的抑制剂和诱导剂。
T20033	Direct Violet 1 NSC75778,NSC 75778,Airedale Violet ND,NSC-75778,直接青莲N,Direct Violet N,CCRIS 2413	SARS-CoV	Microbiology/Virology
	Direct Violet 1 (CCRIS 2413) 是一种偶氮染料，是纺织品染料，也是 SARS-CoV-2 刺突蛋白和 ACE2 抑制剂之间的蛋白质相互作用，IC50为 1.47-2.63 µM。
T1406	Amantadine hydrochloride 盐酸金刚烷胺,1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride	Dopamine Receptor; Influenza Virus	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Amantadine hydrochloride (CI-719) 是一种抗病毒药物，用于预防或对症治疗甲型流感和帕金森病。它阻断质子流通过 M2 离子通道，从而阻止病毒 RNA 释放到感染细胞的细胞质中。
T0100	Atazanavir sulfate 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦	P450; SARS-CoV; HIV Protease; P-gp	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Atazanavir sulfate (BMS-232632 sulfate) 是一种氮杂肽和 HIV 蛋白酶抑制剂，与其他抗 HIV 药物联合用于治疗 HIV 感染和艾滋病。它也是SARS-CoV 3CLpro 抑制剂，IC50为 3.49 μM。
T60861	SARS-CoV-2 nsp3-IN-1	Others	Others
	SARS-CoV-2 nsp3-IN-1 (Compound 15c) 对冠状病毒的大结构域，尤其是 SARS-CoV-2 Mac1，表现出显著性的选择性。SARS-CoV-2 nsp3-IN-1 可抑制 Mac1 ADP-核苷酸水解酶的活性，是 Mac1的抑制剂 (IC50 = 6.1 μM)。
T60686	SARS-CoV-2 Mpro-IN-1	Others	Others
	SARS-CoV-2 Mpro-IN-1 (化合物 16b-3) 是SARS-CoV-2主要蛋白酶 (Mpro) 的选择性不可逆抑制剂（IC50 = 116 nM）。
T62829	SARS-CoV-2 nsp14-IN-1	Others	Others
	SARS-CoV-2 nsp14-IN-1 (Compound 3) 是一种典型的 SARS-CoV-2Nsp14 Mtase 双底物抑制剂 (IC50: 0.061 μM)。SARS-CoV-2 nsp14-IN-1 对人类甲基转移酶表现出良好的选择性，可拮抗 10 种人甲基转移酶（如组蛋白赖氨酸、蛋白精氨酸、DNA 和 RNA 等）。
T63537	SARS-CoV-2 3CLpro-IN-1	Others	Others
	SARS-CoV-2 3CLpro-IN-1 (Compound 14c) is a highly potent inhibitor specifically designed to target and inhibit the activity of SARS-CoV-2 3CL pro, which is a cysteine-protease found in the main coronaviruses. This particular enzyme has been recognized as a highly promising target for the development of effective antiviral drugs. Therefore, SARS-CoV-2 3CLpro-IN-1 holds significant potential for advancing research and development in the field of infectious diseases [1].
T72230	SARS-CoV-2/MERS Mpro-IN-1	Others	Others
	SARS-CoV-2/MERS Mpro-IN-1 是一种有效的SARS-CoV-2和MERS 主要蛋白酶抑制剂，IC50值分别为 0.10、0.06 µM。
T77516	SARS-CoV-2-IN-39	Antiviral; SARS-CoV	Immunology/Inflammation; Microbiology/Virology
	SARS-CoV-2-IN-39是一种 SARS-CoV-2 抑制剂，EC50 为 1 μM。 SARS-CoV-2-IN-39 具有抗病毒活性，通过抑制 SKP2 蛋白并稳定 BECN1 来抑制 SARS-CoV-2。
T60919	SARS-CoV-2-IN-13	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-13 (compound 6) 是氯硝柳胺的类似物。在人血浆和肝S9酶测定中，SARS-CoV-2-IN-13 比氯硝柳胺更稳定。SARS-CoV-2-IN-13 口服给药时可以提高生物利用度和半衰期。SARS-CoV-2-IN-13 是SARS-CoV-2的有效抑制剂，IC50值为 0.057 μM。
T9876	1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]Piperazine	Others	Others
	Piperazine,1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-是一种哌嗪衍生物，显示出抗 SARS-CoV-2活性。
T60095	CCF0058981	SARS-CoV	Microbiology/Virology
	CCF0058981 (CCF981) 是3-氯苯基类似物，是一种非共价 SARS-CoV-2 3CLpro(SC2)抑制剂，IC50为 68 nM。CCF0058981 抑制 SC1 (SARS-CoV-1 3CLpro)，IC50为 19 nM。CCF0058981 具有抗病毒功效，具有用于 COVID-19 研究的潜力。
T60951	Molnupiravir EIDD-2801,Lagevrio,MK-4482	SARS-CoV; Influenza Virus	Microbiology/Virology
	Molnupiravir (MK-4482) (EIDD-2801) 是核糖核苷类似物 EIDD-1931 的异丙酯前体药物，具有口服生物利用度。Molnupiravir 可用于 COVID-19 ，季节性和流行性流感的研究，对多种冠状病毒和流感病毒具有广谱的抗病毒活性，例如，SARS-CoV-2，MERS-CoV，SARS-CoV。
T9066	Merafloxacin CI 934	SARS-CoV	Microbiology/Virology
	Merafloxacin (CI 934) 是一种氟喹诺酮类抗菌药物，也被确定为 SARS-CoV-2 的 1 PRF 抑制剂。它对革兰氏阳性菌和革兰氏阴性菌具有体外活性。
T78704	PLpro/RBD-IN-1	SARS-CoV	Microbiology/Virology
	PLpro/RBD-IN-1 为 SARS-CoV-2 PLpro 与刺突蛋白 RBD的双重抑制剂，具有抗新型冠状病毒的活性，看用于研究病毒感染。
T72505L	CTP Synthetase-IN-1 Ammonium salt CTPS-IN-1 Ammonium salt,CTP Synthetase-IN-1 Ammonium salt（2338811-71-3 Free base)	Others	Others
	CTP Synthetase-IN-1 Ammonium salt 是一种具有口服活性和高效性的胞苷 5'-三磷酸合成酶 (CTPS) 抑制剂，具有潜在的抗菌抗炎抗肿瘤活性，可用于研究 SARS-CoV-2病毒感染。
T38271	TH1217 TH 1217	Others	Others
	TH1217 是一种有效的、选择性的 dCTPase pyrophosphatase 1 (dCTPase) 抑制剂，IC50 值为 47 nM。TH1217 可增强胞苷类似物在白血病细胞中的细胞毒性作用。TH1217 还可以调节 SARS-Cov-2 相互作用体，因此它具有抗 COVID-19 的活性。
T0860L	Mefloquine Ro215998,WR 142490,Ro-215998,氟甲喹羟哌啶,Lariam,Ro 215998	Others	Others
	Mefloquine (Ro 215998) 是一种喹啉抗疟药，是一种抗 SARS-CoV-2 进入抑制剂。 Mefloquine 也是一种 K+ 通道 (KvQT1/minK) 拮抗剂，IC50 为 ~1 μM。它可用于疟疾、系统性红斑狼疮和癌症研究。
T4578	Tipranavir PNU-140690	SARS-CoV; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Tipranavir 是一种蛋白酶抑制剂，对1种以上蛋白酶抑制剂耐药的HIV-1具有抑制作用。Tipranavir 可有效抑制 HIV-1 蛋白酶酶活性和二聚化，对抗多种蛋白酶抑制剂(PI)的HIV-1分离株具有有效的活性（IC50 为 66-410 nM）。Tipranavir 对SARS-CoV-2 3CLpro 活性有抑制作用。
T0211L	Azelastine hydrochloride Optivar,Azelastine HCl,Allergodil,盐酸氮卓斯汀,Astelin	SARS-CoV; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Azelastine hydrochloride (Astelin) 是一种选择性组胺 1拮抗剂，可研究过敏性鼻炎、哮喘、糖尿病高脂血症和 SARS-CoV-2 。
T0211	Azelastine Azelastina,Astelin,Azelastinum,氮卓斯汀	SARS-CoV; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Azelastine (Azelastinum) 是一种选择性组胺 1 拮抗剂，可研究过敏性鼻炎、哮喘、糖尿病高脂血症和 SARS-CoV-2 。
T5863	Indinavir sulfate L735524 sulfate,MK-639 sulfate,硫酸茚地那韦	SARS-CoV; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Indinavir sulfate (L735524 sulfate) 是一种 HIV 蛋白酶抑制剂。它抑制 HIV-1 蛋白酶，IC50 值为 0.41 nM，Ki 值为 0.24 nM。它也是SARS-CoV 3CLpro 抑制剂，IC50为 1.71 μM。
T0860	Mefloquine hydrochloride Mefloquin hydrochloride,Mefloquine HCl,盐酸甲氟喹	Potassium Channel; SARS-CoV; Reactive Oxygen Species; Parasite; Autophagy	Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; NF-κB
	Mefloquine hydrochloride (Mefloquin hydrochloride) 是喹啉抗疟药，是抗 SARS-CoV-2进入抑制剂，可研究疟疾、系统性红斑狼疮和癌症。它也是 K+通道(KvQT1/minK) 拮抗剂，IC50约为 1 μM。
T6190	Telaprevir VX-950,LY-570310,Incivek,MP-424,特拉匹韦	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Telaprevir (Incivek) 是一种选择性可逆的HCV NS3-4A 蛋白酶抑制剂，作用于基因 1型 (H 株) NS3 蛋白酶结构域和 NS4A 辅因子肽，Ki 为 7 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。
T22394	Paritaprevir ABT450,ABT-450,帕利普韦,Veruprevir	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂，对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂，IC50为 1.31 μM。
T1525	Ritonavir RTV,利托那韦,Abbott 84538,A 84538,ABT 538	Apoptosis; SARS-CoV; HIV Protease	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Ritonavir (ABT 538) 是一种 HIV 蛋白酶抑制剂，可研究 HIV 感染和 AIDS 。它也是 SARS-CoV 3CLpro 的抑制剂，IC50为 1.61 μM。
T1623	Lopinavir ABT-378,洛匹那韦	SARS-CoV; HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Lopinavir (ABT-378) 是一种选择性肽模拟 HIV-1 蛋白酶的高效抑制剂。它通过阻止 HIV-1 的成熟而起作用，从而阻断其感染性。它也是 SARS-CoV 3CLpro 的抑制剂。
T3334	Velpatasvir GS-5816,维帕他韦	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Velpatasvir (GS-5816) 是一种的 HCV NS5A 抑制剂。它也是 SARS-CoV 3CLpro 的抑制剂，IC50为 2.16 μM。
T76900	Adintrevimab
	Adintrevimab (ADG 20)，一种人IgG1单克隆抗体，针对SARS-CoV(SARS-CoV)。它能抑制SARS-CoV-2变体及其他具有大流行潜力的SARS样冠状病毒。
T79279	SARS-CoV-2 Mpro-IN-8	SARS-CoV	Microbiology/Virology
	SARS-CoV-2 Mpro-IN-8（compound 6b）是一抗SARS-CoV-2抗病毒化合物。
T60962	SARS-CoV-2-IN-18	Others	Others
	SARS-CoV-2-IN-18 (Compound 26) 是 SARS-CoV-2 3C-样蛋白酶的有效抑制剂 (IC50 = 45 nM)。
T79676	SARS-CoV-2 3CLpro-IN-21	Virus Protease	Microbiology/Virology
	SARS-CoV-2 3CLpro-IN-21（Compound D6）作为一种抑制剂，不可逆且共价地作用于SARS-CoV-2 3CLpro，展现出0.03μM的IC50值。该化合物同样对SARS-CoV-1 3CLpro具有抑制效果，其IC50为0.12 μM。
T79426	SARS-CoV-2-IN-61	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-61（化合物 8i）是SARS-CoV-2 PLpro的抑制剂，其抗病毒活性表现在其IC50值为16 µM。
T69548	UAWJ9-36-1	Others	Others
	UAWJ9-36-1 is a SARS-CoV-2 Protease inhibitor (IC50 = 51 nM). UAWJ9-36-1 showed potent binding and enzymatic inhibition against the Mpro's from SARS-CoV-2, SARS-CoV, MERS-CoV, HCoV-OC43, HCoV-NL63, HCoV-229E, and HCoV-HKU1. UAWJ9-36-1 is a promising candidate to be further developed as a broad-spectrum coronavirus antiviral.
T79660	SARS-CoV-2 3CLpro-IN-17	SARS-CoV	Microbiology/Virology
	SARS-CoV-2 3CLpro-IN-17 (Compound 3h)为选择性SARS-CoV-2 3CLpro抑制剂，具有0.322μM的IC50s值。
T79243	SARS-CoV-2-IN-43	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-43(Compound 8h)是一种有效的抗病毒剂，能够抑制SARS-CoV-2的复制。
T81207	SARS-CoV-2-IN-64	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-64（compound 9）为鹅去氧胆酸衍生物，对SARS-CoV-2刺突糖蛋白具有显著抑制作用。
T79227	SARS-CoV-2-IN-49	SARS-CoV	Microbiology/Virology
	SARS-CoV-2-IN-49为针对SARS-CoV-2主要蛋白酶的一种不可逆共价结合抑制剂。
T72312	SARS-CoV-2 3CLpro-IN-10	Others	Others
	SARS-CoV-2 3CLpro-IN-10(5d)为一种有效的抗 SARS-CoV-2 3CL 蛋白酶抑制剂，其IC50值仅为190 nM，同时对SARS-CoV-1的IC50值为790 nM，对MERS-CoV的IC50值则为70 nM，显示出广谱的抗病毒活性。

化合物

MERS-CoV-IN-1

Cat.No: T9614

Target: SARS-CoV

Cat.No: T9458

Target: SARS-CoV

SARS-CoV-IN-1

Cat.No: T12837

Target: Others

Cat.No: T7872

Target: Others

SARS-CoV MPro-IN-1

Cat.No: T37174

Target: Others

SARS-CoV-2-IN-1

Cat.No: T12836

Target: Others

Cat.No: T9618

Target: SARS-CoV

PLpro inhibitor

Cat.No: T12502

Synonym: 5-(乙酰氨基)-2-甲基-N-[(1R)-1-(1-萘基)乙基]苯甲酰胺

Target: SARS-CoV

Cat.No: T15781

Target: Serine/threonin kinase, AAK1 (AP2 associated kinase 1)

SARS-CoV-2 nsp13-IN-1

Cat.No: T62413

Target: Antiviral

Cat.No: T0100L

Synonym: Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632

Target: P450, SARS-CoV, HIV Protease, P-gp

Direct Violet 1

Cat.No: T20033

Synonym: NSC75778,NSC 75778,Airedale Violet ND,NSC-75778,直接青莲N,Direct Violet N,CCRIS 2413

Target: SARS-CoV

Amantadine hydrochloride

Cat.No: T1406

Synonym: 盐酸金刚烷胺,1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride

Target: Dopamine Receptor, Influenza Virus

Atazanavir sulfate

Cat.No: T0100

Synonym: 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦

Target: P450, SARS-CoV, HIV Protease, P-gp

SARS-CoV-2 nsp3-IN-1

Cat.No: T60861

Target: Others

SARS-CoV-2 Mpro-IN-1

Cat.No: T60686

Target: Others

SARS-CoV-2 nsp14-IN-1

Cat.No: T62829

Target: Others

SARS-CoV-2 3CLpro-IN-1

Cat.No: T63537

Target: Others

SARS-CoV-2/MERS Mpro-IN-1

Cat.No: T72230

Target: Others

SARS-CoV-2-IN-39

Cat.No: T77516

Target: Antiviral, SARS-CoV

SARS-CoV-2-IN-13

Cat.No: T60919

Target: SARS-CoV

1-(4-fluorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]Piperazine

Cat.No: T9876

Target: Others

Cat.No: T60095

Target: SARS-CoV

Cat.No: T60951

Synonym: EIDD-2801,Lagevrio,MK-4482

Target: SARS-CoV, Influenza Virus

Cat.No: T9066

Synonym: CI 934

Target: SARS-CoV

Cat.No: T78704

Target: SARS-CoV

CTP Synthetase-IN-1 Ammonium salt

Cat.No: T72505L

Synonym: CTPS-IN-1 Ammonium salt,CTP Synthetase-IN-1 Ammonium salt（2338811-71-3 Free base)

Target: Others

Cat.No: T38271

Synonym: TH 1217

Target: Others

Cat.No: T0860L

Synonym: Ro215998,WR 142490,Ro-215998,氟甲喹羟哌啶,Lariam,Ro 215998

Target: Others

Cat.No: T4578

Synonym: PNU-140690

Target: SARS-CoV, HIV Protease

Azelastine hydrochloride

Cat.No: T0211L

Synonym: Optivar,Azelastine HCl,Allergodil,盐酸氮卓斯汀,Astelin

Target: SARS-CoV, Histamine Receptor

Cat.No: T0211

Synonym: Azelastina,Astelin,Azelastinum,氮卓斯汀

Target: SARS-CoV, Histamine Receptor

Indinavir sulfate

Cat.No: T5863

Synonym: L735524 sulfate,MK-639 sulfate,硫酸茚地那韦

Target: SARS-CoV, HIV Protease

Mefloquine hydrochloride

Cat.No: T0860

Synonym: Mefloquin hydrochloride,Mefloquine HCl,盐酸甲氟喹

Target: Potassium Channel, SARS-CoV, Reactive Oxygen Species, Parasite, Autophagy

Cat.No: T6190

Synonym: VX-950,LY-570310,Incivek,MP-424,特拉匹韦

Target: HCV Protease, SARS-CoV

Cat.No: T22394

Synonym: ABT450,ABT-450,帕利普韦,Veruprevir

Target: HCV Protease

Cat.No: T1525

Synonym: RTV,利托那韦,Abbott 84538,A 84538,ABT 538

Target: Apoptosis, SARS-CoV, HIV Protease

Cat.No: T1623

Synonym: ABT-378,洛匹那韦

Target: SARS-CoV, HIV Protease

Cat.No: T3334

Synonym: GS-5816,维帕他韦

Target: HCV Protease, SARS-CoV

Cat.No: T76900

SARS-CoV-2 Mpro-IN-8

Cat.No: T79279

Target: SARS-CoV

SARS-CoV-2-IN-18

Cat.No: T60962

Target: Others

SARS-CoV-2 3CLpro-IN-21

Cat.No: T79676

Target: Virus Protease

SARS-CoV-2-IN-61

Cat.No: T79426

Target: SARS-CoV

Cat.No: T69548

Target: Others

SARS-CoV-2 3CLpro-IN-17

Cat.No: T79660

Target: SARS-CoV

SARS-CoV-2-IN-43

Cat.No: T79243

Target: SARS-CoV

SARS-CoV-2-IN-64

Cat.No: T81207

Target: SARS-CoV

SARS-CoV-2-IN-49

Cat.No: T79227

Target: SARS-CoV

SARS-CoV-2 3CLpro-IN-10

Cat.No: T72312

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T7060	Amantadine 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine	Others	Others
	Amantadine (1-Aminoadamantane) 是抗病毒药物，也是是 NMDA 型谷氨酸受体的弱拮抗剂，能促进高多巴胺的释放，并阻断多巴胺的再摄取。
T1188	Mizoribine Bredinin,NSC 289637,咪唑立宾,HE 69	HCV Protease; SARS-CoV; Tyrosinase	Microbiology/Virology; Proteases/Proteasome
	Mizoribine (NSC-289637) 是一种免疫抑制剂，抑制HCVRNA 复制，有抗 HCV 活性，IC50约为 100 μM。它抑制SARS-CoV 复制，对 SARS-CoV Frankfurt-1 和 SARS-CoV HKU39849 的 IC50分别为 3.5 μg/mL 和 16 μg/mL。
T9715	Aplidine	SARS-CoV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Aplidine 是有效的eEF1A2(KD=80 nM) 靶向的抗癌药物。Aplidine 具有抗病毒活性，抑制SARS-CoV-2的 IC90为 0.88 nM。Aplidine 在多发性骨髓瘤，晚期癌症及 COVID-19 领域有研究的价值。
T8689	Chloroquine CQ,氯喹	SARS-CoV; TLR; HIV Protease; Antibiotic; Parasite; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Chloroquine 是一种 Toll 样受体抑制剂，可以抑制自噬。Chloroquine 具有抗疟疾和抗炎活性，广泛用于治疗疟疾和类风湿性关节炎。Chloroquine 还具有抗 SARS-CoV-2 (COVID-19) 活性、抗 HIV-1 活性。
T3S1447	Arteannuin B	SARS-CoV; Ferroptosis	Apoptosis; Microbiology/Virology
	Arteannuin B 与青蒿素共同存在，有强效抗疟活性，具有抗 SARS-CoV-2 的活性，EC50为 10.28 μM。
T79947	10-Hydroxyaloin A	SARS-CoV	Microbiology/Virology
	10-Hydroxyaloin A有效抑制SARS-CoV-2，与SARS-CoV-2 Mpro活性位点显著结合。
T80010	(25S)-Antcin B	SARS-CoV	Microbiology/Virology
	Antcin-B是3CLPro的高亲和力有效抑制剂，可用于SARS-CoV-2的研究。
T73900	(±)-Alliin	Others	Others
	(±)-Alliin 是大蒜的主要活性成分。(±)-Alliin 被认为是SARS-CoV-2 (Mpro)的虚拟抑制剂。
T75533	Dihydromaniwamycin E	Others	Others
	Dihydromaniwamycin E 是一种热休克代谢物，对influenza 和SARS-CoV-2病毒具有抗病毒活性。
T75534	Maniwamycin E	Others	Others
	Maniwamycin E，一种耐热链霉菌培养提取物中分离得到的马尼瓦霉素衍生物，展示了对SARS-CoV-2和H1N1流感病毒的抗病毒活性。
T75540	Ipomoeassin F	Others	Others
	Ipomoeassin F 是一种高效且具有选择性的内质网(ER)蛋白转位抑制剂，它通过作用于ER膜上的Sec61复合物（Sec61α）的成孔亚基来实现其功能。此化合物能特异性抑制SARS-CoV-2蛋白在ER膜上的转位，同时阻碍分泌蛋白和I型跨膜蛋白（TMP）的ER转运，但对III型TMP的转运不产生影响。

天然产物

Cat.No: T7060

Synonym: 1-Aminoadamantane,1-金刚烷胺,金刚烷胺,1-Adamantanamine,1-Adamantylamine

Target: Others

Cat.No: T1188

Synonym: Bredinin,NSC 289637,咪唑立宾,HE 69

Target: HCV Protease, SARS-CoV, Tyrosinase

Cat.No: T9715

Target: SARS-CoV, DNA/RNA Synthesis

Cat.No: T8689

Synonym: CQ,氯喹

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

Cat.No: T3S1447

Target: SARS-CoV, Ferroptosis

10-Hydroxyaloin A

Cat.No: T79947

Target: SARS-CoV

Cat.No: T80010

Target: SARS-CoV

Cat.No: T73900

Target: Others

Dihydromaniwamycin E

Cat.No: T75533

Target: Others

Cat.No: T75534

Target: Others

Cat.No: T75540

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-06626	SARS-COV-2 BQ.1/BQ.1.1 (Omicron) Nucleoprotein/NP Protein (His)	SARS-CoV-2	E. coli
	SARS-COV-2 BQ.1/BQ.1.1 (Omicron) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.36 kDa and the accession number is YP_009724397.2.
TMPY-06452	SARS-CoV-2 (P.1) Spike S1+S2 trimer Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 (P.1) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 136.59 kDa and the accession number is YP_009724390.1.
TMPY-06448	SARS-CoV-2 (AY.1) Spike S1+S2 trimer Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 (AY.1) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 136.19 kDa and the accession number is YP_009724390.1.
TMPK-01348	3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306) COVID-19,3CL Protease,M Proteinase,3CL Pro...	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306) is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.
TMPY-06616	SARS-CoV-2 BJ.1 (Omicron) Spike S1+S2 trimer Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 BJ.1 (Omicron) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 136.37 kDa and the accession number is YP_009724390.1.
TMPY-06496	SARS-CoV-2 XE(BA.1 x BA.2) Nucleocapsid Protein (His)	SARS-CoV-2	E. coli
	SARS-CoV-2 XE(BA.1 x BA.2) Nucleocapsid Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.75 kDa and the accession number is YP_009724397.2.
TMPY-06632	SARS-CoV-2 XBB.1 (Omicron) Spike S1+S2 trimer Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 XBB.1 (Omicron) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 136.31 kDa and the accession number is YP_009724390.1.
TMPY-06653	SARS-COV-2 XBB.1 (Omicron) Spike RBD Protein (His & Avi), Biotinylated	SARS-CoV-2	HEK293 Cells
	SARS-COV-2 XBB.1 (Omicron) Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.38 kDa and the accession number is YP_009724390.1.
TMPY-06492	SARS-CoV-2 XD(BA.1 x AY.4) Spike S1+S2 trimer Protein (His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 XD(BA.1 x AY.4) Spike S1+S2 trimer Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 137.32 kDa and the accession number is YP_009724390.1.
TMPH-02212	TLR8 Protein, Human, Recombinant (His) TLR8,Toll-like receptor 8	Human	P. pastoris (Yeast)
	Endosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against pathogens through recognition of RNA degradation products specific to microorganisms that are initially processed by RNASET2. Recognizes GU-rich single-stranded RNA (GU-rich RNA) derived from SARS-CoV-2, SARS-CoV-1 and HIV-1 viruses. Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the recruitment of TIR-con...
TMPH-02236	TMPRSS2 Protein, Human, Recombinant (E. coli, His) Transmembrane protease serine 2,TMPRSS2,Serine protease ...	Human	E. coli
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia....
TMPH-02237	TMPRSS2 Protein, Human, Recombinant (His & Myc) Serine protease 10,Transmembrane protease serine 2,...	Human	HEK293 Cells
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia....
TMPH-01283	EEF1A1 Protein, Human, Recombinant (His) EF-1-alpha-1,EEF1A,EEF1A...	Human	E. coli
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IFNG promoter-binding complex with TXK and PARP1.; (Microbial infection) Required for the translation of viral proteins and viral replication during human coronavirus SARS-CoV-2 infection.
TMPH-01284	EEF1A1 Protein, Human, Recombinant EF-Tu,LENG7,EEF1A,eEF1A-1,EF1...	Human	E. coli
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IFNG promoter-binding complex with TXK and PARP1.; (Microbial infection) Required for the translation of viral proteins and viral replication during human coronavirus SARS-CoV-2 infection.
TMPJ-01425	SARS-CoV-2 NSP1 Protein (His) SARS-CoV 2 nsp1,SARS-	SARS-CoV-2	E. coli
	The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close associa...
TMPJ-00679	SGTA Protein, Human, Recombinant (His) α-SGT,Alpha-SGT,SGT,Small Glutamine-Rich Tetratricopeptide R...	Human	E. coli
	Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV...
TMPY-06885	SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)
	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) AMPK, AMPK(α1, β1, γ1)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-02030	CD82 Protein, Human, Recombinant (His) CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,T...	Human	HEK293 Cells
	CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud...
TMPY-01894	SIGIRR Protein, Human, Recombinant (His) TIR8,single immunoglobulin and toll-interleukin 1 r...	Human	HEK293 Cells
	SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01247	FLT3 Protein, Human, Recombinant (T227M, His) FLK2,FLK-2,CD135,STK1,fms-related tyrosine...	Human	HEK293 Cells
	FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) thyroid peroxidase,MSA,TPX,TDH2A	Human	Baculovirus Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPY-03290	HGF Protein, Mouse, Recombinant hepatocyte growth factor (hepapoietin A,NK1,scatter...	Mouse	HEK293 Cells
	HGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 79.3 kDa and the accession number is Q08048-1.
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc) WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...	Human	HEK293 Cells
	TIGIT Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is Q495A1-1.
TMPY-01147	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) RSPO,CRISTIN3,R-spondin 1	Human	HEK293 Cells
	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-04346	PD-L2 Protein, Human, Recombinant (His) PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed...	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00947	VCAM-1 Protein, Human, Recombinant (hFc) INCAM-100,CD106,VCAM-1,vascular c...	Human	HEK293 Cells
	VCAM-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 100.8 kDa and the accession number is P19320-1.
TMPY-01949	CD19 Protein, Human, Recombinant (His) CD19 molecule,B4,CVID3	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is P15391-1.
TMPY-04165	FGFR3 Protein, Human, Recombinant (His) JTK4,CEK2,fibroblast growth factor receptor 3,HSFGFR3EX,CD33...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P22607-1.
TMPY-00820	IgG1 Fc Protein, Human, Recombinant (C103S) Ighg1,IgG1 Fc	Human	HEK293 Cells
	IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His) HHF5,CD220,insulin receptor	Human	HEK293 Cells
	Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
TMPY-04348	CTLA-4 Protein, Human, Recombinant (His) ALPS5,CD152,GRD4,cytotoxic T-lymphocyte-associated ...	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number is P16410-1.
TMPY-02813	ErbB4 Protein, Human, Rhesus, Recombinant (His) erb-b2 receptor tyrosine kinase 4	Human,Rhesus	HEK293 Cells
	ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His) thymic stromal lymphopoietin	Human	HEK293 Cells
	TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His) D1S166E,tumor necrosis factor receptor sup...	Human	HEK293 Cells
	CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-00853	IL-1RA Protein, Human, Recombinant DIRA,IL1RA,interleukin 1 receptor antagoni...	Human	E. coli
	IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-01850	CEACAM3 Protein, Human, Recombinant (His) W282,W264,CEA,CD66D,CGM1,MGC11987...	Human	HEK293 Cells
	CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp...
TMPY-02245	SNAP-25 Protein, Human, Recombinant (His) synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ	Human	E. coli
	Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-00203	LOXL2 Protein, Mouse, Recombinant (His) 1110004B06Rik,4930526G1<...	Mouse	HEK293 Cells
	Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-01851	CD73 Protein, Human, Recombinant (His) eN,NT5,E5NT,NT,5'-nucleotidase, ecto (CD73),NTE,CALJA,eNT,CD...	Human	HEK293 Cells
	CD73 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.2 kDa and the accession number is P21589-1.
TMPY-01281	ACVR2B Protein, Mouse, Recombinant (His) ActRIIB,activin A receptor, type IIB,4930516B21...	Mouse	HEK293 Cells
	ACVR2B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is P27040-1.
TMPY-03967	BTN3A3 Protein, Human, Recombinant (His) BTF3,BTN3.3,butyrophilin subfamily 3 member A3,BTN3A3	Human	HEK293 Cells
	BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-02525	RGMA Protein, Human, Recombinant (His) repulsive guidance molecule family member a,RGM	Human	HEK293 Cells
	RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form...
TMPY-05208	PD-L1 Protein, Human, Recombinant CD274 molecule,PDCD1L1,PD-L1,PDL<...	Human	HEK293 Cells
	PD-L1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.2 kDa and the accession number is Q9NZQ7-1.
TMPY-00978	Progranulin Protein, Human, Recombinant (His) PGRN,PCDGF,CLN11,Granulin,GP88,GEP,Granuli...	Human	HEK293 Cells
	Progranulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.2 kDa and the accession number is P28799-1.
TMPY-03407	NQO1 Protein, Human, Recombinant (His) NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1...	Human	E. coli
	NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPY-01258	IL-13RA1 Protein, Human, Recombinant (His) NR4,interleukin 13 receptor, alpha 1,CD2	Human	HEK293 Cells
	IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1.
TMPY-03531	PSGL-1/CD162 Protein, Human, Recombinant (His) selectin P ligand,PSGL-1,PSGL1,CD1	Human	HEK293 Cells
	PSGL-1/CD162 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q14242-1.
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重组蛋白

SARS-COV-2 BQ.1/BQ.1.1 (Omicron) Nucleoprotein/NP Protein (His)

Cat.No: TMPY-06626

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 (P.1) Spike S1+S2 trimer Protein (His)

Cat.No: TMPY-06452

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 (AY.1) Spike S1+S2 trimer Protein (His)

Cat.No: TMPY-06448

Species: SARS-CoV-2

Expression System: HEK293 Cells

3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306)

Cat.No: TMPK-01348

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 BJ.1 (Omicron) Spike S1+S2 trimer Protein (His)

Cat.No: TMPY-06616

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 XE(BA.1 x BA.2) Nucleocapsid Protein (His)

Cat.No: TMPY-06496

Species: SARS-CoV-2

Expression System: E. coli

SARS-CoV-2 XBB.1 (Omicron) Spike S1+S2 trimer Protein (His)

Cat.No: TMPY-06632

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-COV-2 XBB.1 (Omicron) Spike RBD Protein (His & Avi), Biotinylated

Cat.No: TMPY-06653

Species: SARS-CoV-2

Expression System: HEK293 Cells

SARS-CoV-2 XD(BA.1 x AY.4) Spike S1+S2 trimer Protein (His)

Cat.No: TMPY-06492

Species: SARS-CoV-2

Expression System: HEK293 Cells

TLR8 Protein, Human, Recombinant (His)

Cat.No: TMPH-02212

Species: Human

Expression System: P. pastoris (Yeast)

TMPRSS2 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02236

Species: Human

Expression System: E. coli

TMPRSS2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02237

Species: Human

Expression System: HEK293 Cells

EEF1A1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01283

Species: Human

Expression System: E. coli

EEF1A1 Protein, Human, Recombinant

Cat.No: TMPH-01284

Species: Human

Expression System: E. coli

SARS-CoV-2 NSP1 Protein (His)

Cat.No: TMPJ-01425

Species: SARS-CoV-2

Expression System: E. coli

SGTA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00679

Species: Human

Expression System: E. coli

SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)

Cat.No: TMPY-06885

Expression System:

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04451

Species: Human

Expression System: Baculovirus Insect Cells

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03878

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-02501

Species: Human

Expression System: HEK293 Cells

CD82 Protein, Human, Recombinant (His)

Cat.No: TMPY-02030

Species: Human

Expression System: HEK293 Cells

SIGIRR Protein, Human, Recombinant (His)

Cat.No: TMPY-01894

Species: Human

Expression System: HEK293 Cells

FLT3 Protein, Human, Recombinant (T227M, His)

Cat.No: TMPY-01247

Species: Human

Expression System: HEK293 Cells

Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

Cat.No: TMPY-02779

Species: Human

Expression System: Baculovirus Insect Cells

HGF Protein, Mouse, Recombinant

Cat.No: TMPY-03290

Species: Mouse

Expression System: HEK293 Cells

TIGIT Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04970

Species: Human

Expression System: HEK293 Cells

R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01147

Species: Human

Expression System: HEK293 Cells

PD-L2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04346

Species: Human

Expression System: HEK293 Cells

VCAM-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00947

Species: Human

Expression System: HEK293 Cells

CD19 Protein, Human, Recombinant (His)

Cat.No: TMPY-01949

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04165

Species: Human

Expression System: HEK293 Cells

IgG1 Fc Protein, Human, Recombinant (C103S)

Cat.No: TMPY-00820

Species: Human

Expression System: HEK293 Cells

Insulin Receptor Protein, Human, Recombinant (long isoform, His)

Cat.No: TMPY-01146

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Human, Recombinant (His)

Cat.No: TMPY-04348

Species: Human

Expression System: HEK293 Cells

ErbB4 Protein, Human, Rhesus, Recombinant (His)

Cat.No: TMPY-02813

Species: Human,Rhesus

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant (R127A & R130S, His)

Cat.No: TMPY-05220

Species: Human

Expression System: HEK293 Cells

CD30/TNFRSF8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01827

Species: Human

Expression System: HEK293 Cells

IL-1RA Protein, Human, Recombinant

Cat.No: TMPY-00853

Species: Human

Expression System: E. coli

CEACAM3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01850

Species: Human

Expression System: HEK293 Cells

SNAP-25 Protein, Human, Recombinant (His)

Cat.No: TMPY-02245

Species: Human

Expression System: E. coli

LOXL2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00203

Species: Mouse

Expression System: HEK293 Cells

CD73 Protein, Human, Recombinant (His)

Cat.No: TMPY-01851

Species: Human

Expression System: HEK293 Cells

ACVR2B Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01281

Species: Mouse

Expression System: HEK293 Cells

BTN3A3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03967

Species: Human

Expression System: HEK293 Cells

RGMA Protein, Human, Recombinant (His)

Cat.No: TMPY-02525

Species: Human

Expression System: HEK293 Cells

PD-L1 Protein, Human, Recombinant

Cat.No: TMPY-05208

Species: Human

Expression System: HEK293 Cells

Progranulin Protein, Human, Recombinant (His)

Cat.No: TMPY-00978

Species: Human

Expression System: HEK293 Cells

NQO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03407

Species: Human

Expression System: E. coli

IL-13RA1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01258

Species: Human

Expression System: HEK293 Cells

PSGL-1/CD162 Protein, Human, Recombinant (His)

Cat.No: TMPY-03531

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
TMID-0082	Lopinavir-d8
	Lopinavir-d8 是 Lopinavir 的氘代化合物。Lopinavir 的 CAS 号为 192725-17-0。Lopinavir 是一种选择性肽模拟 HIV-1 蛋白酶的高效抑制剂。它通过阻止 HIV-1 的成熟而起作用，从而阻断其感染性。它也是SARS-CoV 3CLpro的抑制剂。
TMIJ-0076	Ritonavir-13C-d3
	Ritonavir-13C-d3 是 Ritonavir 的 13C 和氘代化合物。Ritonavir 的 CAS 号为 155213-67-5。Ritonavir 是一种 HIV 蛋白酶抑制剂，可研究 HIV 感染和 AIDS 。它也是SARS-CoV 3CLpro的抑制剂，IC50为 1.61 μM。
T38297	Ribavirin-13C5 Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...

同位素标记化合物

Cat.No: TMID-0082

Ritonavir-13C-d3

Cat.No: TMIJ-0076

Cat.No: T38297

Synonym: Ribavirin-13C5

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