3
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T60908 |
SARM1-IN-2
|
Others | Others |
SARM1-IN-2 是一种有效的 SARM1 抑制剂,可用于研究代谢系统和神经系统相关疾病。 | |||
T8860 |
DSRM-3716
|
Androgen Receptor | Endocrinology/Hormones |
DSRM-3716 是选择性的SARM1 NADase 抑制剂,IC50为 75 nM,相较于其他 NAD+加工酶、受体和转运蛋白具有选择性。DSRM-3716显示出强大的轴突保护作用。 | |||
T13907 |
Sulfo-ara-F-NMN
CZ-48 |
Others | Others |
Sulfo-ara-F-NMN 是一种具有细胞渗透性的烟酰胺单核苷酸 (NMN) 的类似物。Sulfo-ara-F-NMN 对激活 SARM1具有选择性,对 CD38具有抑制作用, IC50 约为 10 μM。Sulfo-ara-F-NMN 对具有更高的环化酶活性 CZ-48或 NMN 的激活会引起 SARM1的构象变化,导致 cADPR 的产生、NAD 的消耗和非凋亡细胞死亡。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01741 |
SARM1 Protein, Human, Recombinant (His & KSI)
Sterile alpha and Armadillo repeat protein,Sterile alpha mot... |
Human | E. coli |
SARM1 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 48.8 kDa and the accession number is Q6SZW1. | |||
TMPH-01740 |
SARM1 Protein, Human, Recombinant (His & Myc)
Tir-1 homolog,Sterile alpha and Armadillo repeat pr... |
Human | Baculovirus Insect Cells |
SARM1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 80.4 kDa and the accession number is Q6SZW1. |