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Search Results for " s100b "

Targets Recommended: Others

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T11553	Heptamidine dimethanesulfonate SBi4211 dimethanesulfonate	Others	Others
	Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) 是一种与喷他脒有关的、强效的钙结合蛋白 S100B 的抑制剂 (Kd=6.9 μM)，选择性地杀死表达 S100B 的黑素瘤细胞。它是有效的强直性肌营养不良 (DM) 研究工具。
T11553L	Heptamidine SBi4211	Others	Others
	Heptamidine is an effective Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM). It selectively kills melanoma cells with S100B over those without S100B. It is a useful tool for the investigation of Myotonic dystrophy.
T68231	SEN205A	Others	Others
	SEN205A is a novel s100b inhibitor
T28355	Pentamidine dimesylate	Others	Others
	Pentamidine dimesylate is an inhibitor of calcium-dependent complex formation with p53 [(Ca)S100B-p53) in malignant melanoma (MM). Pentamidine dimesylate restores p53 tumor suppressor activity in vivo.
T85157	Nε-(1-Carboxyethyl)-L-lysine CEL	Others	Others
	Nε-(1-Carboxyethyl)-L-lysine (CEL), a known advanced glycation end product (AGE), forms through the interaction of methyl glyoxal and lysine residues within proteins. Unlike its free form, protein-bound CEL can attach to the receptor for AGEs (RAGE). Its concentrations are notably higher in the lenses of diabetic cataract patients and are reduced in rat heart mitochondria following sustained caloric restriction. Furthermore, at 1 mM, CEL impedes glutamate uptake and the release of S100B in rat h...

化合物

Heptamidine dimethanesulfonate

Cat.No: T11553

Synonym: SBi4211 dimethanesulfonate

Pentamidine dimesylate

Cat.No: T28355

Synonym:

Target: Others

Nε-(1-Carboxyethyl)-L-lysine

Cat.No: T85157

Synonym: CEL

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00990	S100B Protein, Mouse, Recombinant (His) S-100 protein subunit beta,S-100 protein beta chain,S100...	Mouse	E. coli
	S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotective effects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage, which easily penetrates into cerebrospinal flui...
TMPY-02531	S100B Protein, Human, Recombinant (His) S100β,S100-B,S100beta,S100 calcium binding protein ...	Human	E. coli
	S100B Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 12 kDa and the accession number is A0A0S2Z4C5.
TMPK-01369	S100B Protein, Canine, Recombinant (hFc) S100 calcium-binding,S100-B,100β,100beta,NEF,Protein S100,S1...	Canine	HEK293 Cells
	S100B, a calcium-binding protein of the EF-hand type exerts both intracellular and extracellular functions.The intracellular, and extracellular, roles of S100B are attractive therapeutic targets for the treatment of both cardiac and vascular disease.
TMPY-03020	S100B Protein, Mouse, Recombinant (hFc) AI850290,S100 calcium binding protein B,Bpb	Mouse	HEK293 Cells
	S100B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is P50114.
TMPY-00913	S100B Protein, Human, Recombinant (hFc) NEF,S100 calcium binding protein B,S100beta,S100-B,...	Human	HEK293 Cells
	S100B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 37.2 kDa and the accession number is A0A0S2Z4C5.