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Search Results for " s.aureus "

Targets Recommended: Others

5

抑制剂 & 化合物

5

天然产物

13

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T60804	Antibacterial agent 114	Others	Others
	Antibacterial agent 114 (compound 1) 是一种有效的抗菌剂，其对铜绿假单胞菌、枯草芽孢杆菌、大肠杆菌、粪肠球菌、鼠伤寒沙门氏菌的 MIC 值分别为 625、625、625、625、625、1250 和 1250 μM。
T80317	Combi-2
	Combi-2为针对S.aureus、S.sanguis及E.coli具有抗菌活性的肽类化合物。
T63252	Antibacterial agent 113	Others	Others
	Antibacterial agent 113 是有效的抗菌剂 (antibacterial)，对P.aeruginosa、S.mutans、B.subtilis、E.coli、E.faecalis、S.typhimuriumand 和S.aureus microorganisms 表现出抗菌作用，MIC 值均为 15625 μM。
T64197	Antibacterial agent 112	Others	Others
	Antibacterial agent 112 (compound 2) 是一种有效的抗菌剂 (antibacterial)。Antibacterial agent 112 对 P.aeruginosa (MIC: 625 μM)、S.mutans (MIC: 625 μM)、B.subtilis (MIC: 1250 μM)、E.coli (MIC: 1250 μM)、E.faecalis (MIC: 1250 μM)、S.typhimuriumand (MIC: 1250 μM) 和 S.aureus microorganisms (MIC: 1250 μM)具有抗菌活性。
T61251	Antibacterial agent 97	Others	Others
	Antibacterial agent 97 (hit compound) 是一种有效的抗菌剂。Antibacterial agent 97 对大肠杆菌(E.coli)和金黄色酿脓葡萄球菌 (S.aureus)的 MIC 分别为 16 和 16 μg/mL[1]。

化合物

Antibacterial agent 114

Cat.No: T60804

Target: Others

Cat.No: T80317

Antibacterial agent 113

Cat.No: T63252

Target: Others

Antibacterial agent 112

Cat.No: T64197

Target: Others

Antibacterial agent 97

Cat.No: T61251

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3907	Tenuigenin Senegenin,Senegin,远志皂苷元	NF-κB; Caspase; Antibacterial	Apoptosis; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Tenuigenin (Senegenin) 是从中草药远志根中分离出来的主要活性成分，用于中药，具有抗氧化和抗炎活性。它抑制 NF-κB 活化，预防金黄色葡萄球菌诱导的肺炎。
T2909	Fraxetin 7,8-dihydroxy-6-methoxy coumarin,秦皮素,弗拉西汀	Apoptosis; Others	Apoptosis; Others
	Fraxetin (7,8-dihydroxy-6-methoxy coumarin) 是从秦皮中分离出来的一种天然产物，可诱导细胞凋亡，具有抗肿瘤、抗氧化作用和抗炎作用。
T6873	Lauric Acid 月桂酸,Dodecylic acid,dodecanoic acid,Vulvic acid,N-Dodecanoic acid	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	Lauric Acid (Dodecylic acid) 是一种有抗菌活性的中链脂肪酸，对P. acnes，S.aureus 和S. epidermidis 的 EC50值分别为 2，6，4 μg/mL。
T80343	MCF	Others	Others
	MCF为源自蜂毒的抗菌肽，对E.coli W 160-37、S.aureus 8530及B.subtilis展现出抗菌活性，其最小抑菌浓度(MIC)值分别为E.coli W 160-37为35-45 μg/ml，S.aureus 8530为25-35 μg/ml，及B.subtilis为15-25 μg/ml。
T80330	XT-1	Others	Others
	XT-1是一种抗菌肽，源自热带爪蟾Xenopus tropicalis的皮肤分泌物，表现出对S.aureus、E.coli和C.albicans的强烈活性，其最小抑菌浓度(MIC)分别为5μM、6μM和50μM。

天然产物

Cat.No: T3907

Synonym: Senegenin,Senegin,远志皂苷元

Target: NF-κB, Caspase, Antibacterial

Cat.No: T2909

Synonym: 7,8-dihydroxy-6-methoxy coumarin,秦皮素,弗拉西汀

Target: Apoptosis, Others

Cat.No: T6873

Synonym: 月桂酸,Dodecylic acid,dodecanoic acid,Vulvic acid,N-Dodecanoic acid

Target: Others, Endogenous Metabolite, Antibacterial

Cat.No: T80343

Target: Others

Cat.No: T80330

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03518	ACP Protein, S. aureus, Recombinant (GST) acpP,Fatty acid synthase acyl carrier prot...	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 35.5 kDa and the accession number is P0A001.
TMPH-01773	ELANE Protein, Human, Recombinant (GST) Neutrophil elastase,ELA2,Medullas...	Human	E. coli
	Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae. ELANE Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 52.6 kDa and the accession number is P08246.
TMPH-03520	ACP Protein, S. aureus, Recombinant (His & SUMO) acpP,Cytosolic-activating factor,Fatty acid s	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.5 kDa and the accession number is P0A001.
TMPH-00229	Cathelicidin-4 Protein, Bovine, Recombinant (His & SUMO) Cathelicidin-4,Indolicidin,CATHL4	Bovine	E. coli
	Potent microbicidal activity; active against S.aureus and E.coli. Cathelicidin-4 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 17.9 kDa and the accession number is P33046.
TMPH-02875	ROMO1 Protein, Mouse, Recombinant (His) Protein MGR2 homolog,Romo1,Reactive oxygen specie	Mouse	E. coli
	Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.; Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
TMPH-03519	ACP Protein, S. aureus, Recombinant (His) Cytosolic-activating factor,Fatty acid syn...	Staphylococcus aureus	P. pastoris (Yeast)
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.5 kDa and the accession number is P0A001.
TMPY-02835	DEFB103A Protein, Human, Recombinant (His) DEFB3,HBP3,defensin, beta 103A,hBD-3,DEFB103,DEFB-3...	Human	E. coli
	Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. Beta-defensin 3 shows antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Beta-defensin 3 is abundantly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kid...
TMPH-03145	Thanatin Protein, Podisus maculiventris, Recombinant (His & KSI) Thanatin	Podisus maculiventris	E. coli
	Insect defense peptide with a broad spectrum of activity against Gram-positive and Gram-negative bacteria and fungi. No activity against S.aureus. Stops respiration in bacteria but does not permeabilize their inner membranes. Thanatin Protein, Podisus maculiventris, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 17.8 kDa and the accession number is P55788.
TMPH-02879	REG3G Protein, Mouse, Recombinant (His) Regenerating islet-derived protein III-gamma,Reg3g,...	Mouse	P. pastoris (Yeast)
	Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regula...
TMPH-03550	EsxA Protein, S. aureus, Recombinant (His & SUMO) esxA,Type VII secretion sys	Staphylococcus aureus	E. coli
	Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion. Modulates host cell apoptotic pathways and mediates together with EsxB the release of S.aureus from the host cell. By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity. EsxA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27....
TMPH-01575	KRT10 Protein, Human, Recombinant (His) Keratin, type I cytoskeletal 10,Keratin-10,Cytokera...	Human	E. coli
	Plays a role in the establishment of the epidermal barrier on plantar skin.; (Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization.; (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occu...
TMPH-03578	SCIN Protein, S. aureus, Recombinant (His & Myc) scn,Staphylococcal complement inhibitor	Staphylococcus aureus	E. coli
	Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses. SCIN Protein, S. aureus, ...
TMPH-00064	MRJP1 Protein, Apis mellifera, Recombinant (His) Royalactin,Major royal jelly protein 1,Apalbumin 1,MRJP1,56-...	Apis mellifera	P. pastoris (Yeast)
	Induces the differentiation of honeybee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vitellogenin (Vg) and juvenile hormone, and reduces developmental time by increasing the activity of mitogen-activated protein kinase and inducing the 20-hydroxyecdysone protein (20E). Most abundant protein found in the royal jelly which is the food of the queen honey bee larva. The ...

重组蛋白

ACP Protein, S. aureus, Recombinant (GST)

Cat.No: TMPH-03518

Species: Staphylococcus aureus

Expression System: E. coli

ELANE Protein, Human, Recombinant (GST)

Cat.No: TMPH-01773

Species: Human

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03520

Species: Staphylococcus aureus

Expression System: E. coli

Cathelicidin-4 Protein, Bovine, Recombinant (His & SUMO)

Cat.No: TMPH-00229

Species: Bovine

Expression System: E. coli

ROMO1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02875

Species: Mouse

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03519

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

DEFB103A Protein, Human, Recombinant (His)

Cat.No: TMPY-02835

Species: Human

Expression System: E. coli

Thanatin Protein, Podisus maculiventris, Recombinant (His & KSI)

Cat.No: TMPH-03145

Species: Podisus maculiventris

Expression System: E. coli

REG3G Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02879

Species: Mouse

Expression System: P. pastoris (Yeast)

EsxA Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03550

Species: Staphylococcus aureus

Expression System: E. coli

KRT10 Protein, Human, Recombinant (His)

Cat.No: TMPH-01575

Species: Human

Expression System: E. coli

SCIN Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03578

Species: Staphylococcus aureus

Expression System: E. coli

MRJP1 Protein, Apis mellifera, Recombinant (His)

Cat.No: TMPH-00064

Species: Apis mellifera

Expression System: P. pastoris (Yeast)

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