Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70048 |
Sch 58053
|
Others | Others |
Sch 58053 is an analog of Ezetimibe and a selective inhibitor of lymphatic cholesterol transport in the intestine. | |||
T70049 |
Ro 04-5595 free base
|
Others | Others |
Ro 04-5595 is a selective antagonist of NMDA receptors NR2B subunits. Ro 04-5595 had an EC 50 of 186 ± 32 nmol/L. Ro 04-5595 was predicted to bind the EVT-101 binding site, not the ifenprodil-binding site. Specific binding, defined with a new NR2B-specific antagonist Ro 04-5595 at 10 microM was fully inhibited by several compounds with the following rank order of affinities--Ro 25-6981 > CP-101,606 > Ro 04-5595 = ifenprodil >> eliprodil > haloperidol > spermine > spermidine > MgCl2 > CaCl2--and... |