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Search Results for " ritlecitinib tosylate "
Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T69822 Ritlecitinib tosylate

Others Others
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low clearance compound with demonstrated in vivo efficacy. The favorable efficacy and safety profile of this JAK3-specific inhibitor PF-06651600 led to its evaluation in several human clinical studies. JAK3 was among the first of the JAKs targeted for therapeutic intervention due to the strong validation provided by human SCID patients displaying JAK3 deficiencies.
T60565 (2R,5S)-Ritlecitinib

Others Others
(2R,5S)-Ritlecitinib (2R,5S)-PF-06651600) 是有效的选择性 JAK3抑制剂,IC50 值为144.8 nM。
T5382 Ritlecitinib

PF-06651600

JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
Ritlecitinib (PF-06651600) 是一种口服有效的选择性JAK3抑制剂,IC50值为 33.1 nM。

化合物

Ritlecitinib tosylate
Cat.No: T69822
Synonym:
Target: Others
(2R,5S)-Ritlecitinib
Cat.No: T60565
Synonym:
Target: Others
Ritlecitinib
Cat.No: T5382
Synonym: PF-06651600
Target: JAK
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