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Search Results for " rho-kinase "

Targets Recommended: ROCK

64

抑制剂 & 化合物

2

天然产物

1

化合物库

3

重组蛋白

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Cat. No.	Product Name
L7700	神经再生化合物库		524 compounds
	524 种神经再生相关化合物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

神经再生化合物库

Cat.No: L7700

Compounds: 524

Cat. No.	Product Name	Target	Signaling Pathways
T12721	Rho-Kinase-IN-1	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Rho-Kinase-IN-1 是一种 ROCK 抑制剂，对 ROCK1 和 ROCK2 的 Kis 分别为 30.5 nM 和 3.9 nM。 Rho-Kinase-IN-1 可用于细胞过度增殖、重塑、水肿和炎症疾病的研究。
T2633	GSK429286A RHO-15	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	GSK429286A (RHO-15) 是一种选择性ROCK1/2抑制剂，IC50值为14 和 63 nM。
T7391	SAR407899	ROCK; Rho	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	SAR407899 是一种选择性的 ATP 竞争性ROCK 抑制剂，对ROCK-2的IC50值为 135 nM，对人和大鼠ROCK-2的Ki 值分别为 36 和 41 nM。它是 Rho 激酶抑制剂，有效抑制 endothelin-1 诱导的肾阻力动脉收缩。
T14960	Chroman 1	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Chroman 1 是高效的的ROCK 选择性抑制剂，对 ROCK2 (IC50=1 pM) 的抑制作用强于 ROCK1 (IC50=52 pM) 。它对MRCK 也有抑制作用，IC50为 150 nM。
T2155	Thiazovivin	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Thiazovivin 是一种ROCK 抑制剂，能提高 iPSC 的生成效率，对人胚胎干细胞具有保护作用。
T12746	ROCK inhibitor-2	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	ROCK inhibitor-2 是一种 ROCK1和 ROCK2的选择性双重抑制剂，IC50值分别为 17 nM 和2 nM。
T7301	BDP5290	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	BDP5290 是一种有效 ROCK 和 MRCK 抑制剂，对 ROCK1、ROCK2、MRCKα 和 MRCKβ 的 IC50 分别为 5、50 、10 和 100 nM。
T3513	GSK180736A GSK180736	ROCK; GRK; PKA	Cell Cycle/Checkpoint; Cytoskeletal Signaling; GPCR/G Protein; Stem Cells; Tyrosine Kinase/Adaptors
	GSK180736A 是 Rho 相关卷曲螺旋激酶 1 (ROCK1) 抑制剂，IC50值为 100 nM。它也是选择性的ATP-竞争性 G 蛋白偶联受体激酶 2 抑制剂，IC50值为 0.77 μM，其选择性比其他 GRK 高 100 倍以上。
T14989	CMPD101	ROCK; GRK; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; GPCR/G Protein; Stem Cells
	CMPD101 是膜透性的 GRK2/3高选择性小分子抑制剂，IC50分别为 18 nM 和 5.4 nM。它针对 GRK1、GRK5 ROCK-2 和 PKCα 的选择性较小，IC50值分别为 3.1 μM，2.3 μM，1.4 μM 和 8.1 μM，可研究心衰疾病。
T7885	Afuresertib hydrochloride	ROCK; Akt; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells
	Afuresertib hydrochloride 是一个口服有效的，ATP 竞争性的选择性泛Akt 抑制剂，作用于Akt1、Akt2和Akt3，Ki 值分别为 0.08、2和 2.6 nM。
T4095	ZINC00881524 ROCK inhibitor	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	ZINC00881524 (ROCK inhibitor)是一种特异性有效 ROCK 抑制剂。
T15798	LX7101	ROCK; LIM Kinase; PKA	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells; Tyrosine Kinase/Adaptors
	LX7101是 LIMK 和ROCK2高效抑制剂，对LIMK1/2、ROCK、PKA 的IC50分别为24、1.6、10 和小于1 nM。
T4488	GSK-25 GSK25	ROCK; S6 Kinase; mTOR	Cell Cycle/Checkpoint; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	GSK-25 是一种选择性的，具有口服活性的 ROCK1抑制剂。它对 31 种激酶以及 RSK1 和 p70S6K 保持良好的选择性，RSK1的 IC50 为 398 nM，p70S6K 的 IC50 为 1000nM。它可抑制 P450，对 CYP2C9、CYP2D6和 CYP3A4的 IC50分别为2.5、5.2和2.5 μM。
TQ0187	SR-3677	ROCK; Autophagy	Autophagy; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	SR-3677 是一种有效且特异性的 ROCK2 抑制剂，IC50值为3 nM。
T12747	ROCK2-IN-2	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	ROCK2-IN-2 是 ROCK2 的特异性抑制剂（IC50 <1 μM）。
T1898	RKI-1447 RKI1447	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	RKI-1447 是一种高效的ROCK1和ROCK2的小分子抑制剂，IC50值分别为14.5和6.2 nM。
T1870	Y-27632	ROCK; Apoptosis	Apoptosis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Y-27632 是一种 ROCK-I 和 ROCK-II 抑制剂，具有口服有效性、ATP 竞争性。Y-27632 还抑制分离诱导的小鼠前列腺干或祖细胞凋亡。
T7648	HA-100	Myosin; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	HA-100 是蛋白激酶和ROCK 抑制剂，抑制PKG，PKA，PKC 和MLC 激酶的IC50值分别为 4、8、12 和 240 μM。
T2011	RKI1313 RKI 1313,RKI-1313	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	RKI1313 (RKI-1313) 是一种选择性抑制剂，可抑制 ROCK 依赖性信号传导、细胞骨架变化、不依赖锚定的集落形成、迁移和侵袭。
T2482	AT13148	ROCK; SGK; Akt; PKA; S6 Kinase	Cell Cycle/Checkpoint; Cytoskeletal Signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors
	AT13148 是一种 ATP 竞争性 AGC 激酶口服抑制剂，能够抑制 Akt1/Akt2/Akt3、p70S6K、PKA 和 ROCKI/ROCKII 的活性，IC50值分别为 38/402/50、8、3 和 6 nM/4 nM。
T7764	CCG-222740	ROCK; Rho; Ras	Cell Cycle/Checkpoint; Cytoskeletal Signaling; GPCR/G Protein; MAPK; Stem Cells
	CCG-222740 是一种口服有效的选择性Rho/MRTF 途径抑制剂。它也是 α-平滑肌的肌动蛋白表达抑制剂，可减少皮肤纤维化并阻止黑色素瘤转移。
T1911	Afuresertib GSK2110183C,GSK2110183	ROCK; Akt; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells
	Afuresertib (GSK2110183) 是一个选择性，ATP 竞争性，口服有效的泛 Akt 抑制剂，作用于 Akt1、Akt2和 Akt3，Ki 值分别为 0.08、2、2.6 nM。
T6867	Belumosudil KD025,Rezurock,ROCK inhibitor,SLx-2119	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Belumosudil (Rezurock) 是一种选择性的ROCK2抑制剂，对 ROCK1 和 ROCK2 的IC50值分别为 24 µM 和 105 nM，具有抗纤维化作用。
T13384L	Y-33075 dihydrochloride	CaMK; ROCK; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Neuroscience; Stem Cells
	Y-33075 dihydrochloride 是一种选择性ROCK 抑制剂，IC50为 3.6 nM。
T23308	SAR407899 hydrochloride 6-(哌啶-4-氧基)异喹啉-1(2H)-酮盐酸盐	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	SAR407899 hydrochloride 是一种选择性，ATP 竞争性的ROCK 抑制剂，对人和大鼠ROCK2的Ki 值分别为 36 和 41 nM，对ROCK2的IC50值为 135 nM。
TQ0110	ROCK-IN-2 TC-S 7001,Azaindole 1	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	ROCK-IN-2 (Azaindole 1) 是一种选择性，ATP-竞争型的ROCK 抑制剂，对ROCK-1和ROCK-2的IC50值分别为 0.6 和 1.1 nM。
T4276L	Hydroxyfasudil Hydroxy-Fasudil,HA-1100,羟基法舒地尔	ROCK; PKA	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Hydroxyfasudil (Hydroxy-Fasudil) 是一种ROCK 抑制剂，对ROCK1和ROCK2的IC50分别为 0.73 和 0.72 μM。
T3518	GSK269962A GSK269962B,GSK 269962,GSK269962A HCl	ROCK; S6 Kinase	Cell Cycle/Checkpoint; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	GSK269962A (GSK269962A HCl) 是一种有效的ROCK 抑制剂，具有抗炎和血管舒张作用。它作用于重组人ROCK1和ROCK2，IC50分别为 1.6 和 4 nM。
T4276	Hydroxyfasudil Hydrochloride Hydroxyfasudil (HA-1100) HCl,羟基法舒地尔盐酸盐,RHO-激酶抑制剂,HA 1100 hydrochloride	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Hydroxyfasudil Hydrochloride (HA 1100 hydrochloride) 是一种ROCK 抑制剂，对ROCK1和ROCK2的IC50值分别为 0.73 和 0.72 μM。
T1606	Fasudil HA-1077,AT877,法舒地尔	ROCK; Serine/threonin kinase; Calcium Channel; PKA; PKC; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
	Fasudil (HA-1077) 是一种非特异性 RhoA/ROCK 抑制剂，也是 Ca2+通道拮抗剂和血管扩张剂。它对蛋白激酶有抑制作用，ROCK1 的 Ki 值为 0.33 μM，ROCK2 和 PKA、PKC、PKG 的 IC50值分别 0.158 μM 和 4.58 μM、12.30 μM、1.650 μM。
T1725	Y-27632 dihydrochloride 反式-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐,Y-27632 2HCl	ROCK; Apoptosis	Apoptosis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Y-27632 dihydrochloride (Y-27632 2HCl) 是一种 ROCK-I 和 ROCK-II 抑制剂，具有口服有效性、ATP 竞争性。Y-27632 dihydrochloride 还抑制分离诱导的小鼠前列腺干或祖细胞凋亡。
T3060	Fasudil hydrochloride Fasudil (HA-1077) HCl,盐酸法舒地尔,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK; Serine/threonin kinase; Calcium Channel; HIV Protease; PKA; PKC; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
	Fasudil hydrochloride (HA-1077) 是一种非特异性RhoA/ROCK 抑制剂，也抑制蛋白激酶，对 ROCK1、PKA、PKC 和 MLCK 的 Ki 值分别为 0.33 μM、1.0 μM、9.3 μM 和 55 μM。
T7552	H-1152	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	H-1152 是一种膜通透的选择性ROCK 抑制剂，Ki 为 1.6 nM，对ROCK2的IC50为 12 nM。
T61497	Rho-Kinase-IN-2	Others	Others
	Rho-Kinase-IN-2 (Compound 23) is an orally active and selective inhibitor of Rho Kinase (ROCK), which can penetrate the central nervous system (CNS). It exhibits a high affinity for ROCK2 with an inhibition constant (IC50) of 3 nM. This compound is of potential interest for further investigations in the field of Huntington's disease research [1].
T7492	Ripasudil free base K-115 (free base)	ROCK; Antibacterial	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Microbiology/Virology; Stem Cells
	Ripasudil free base (K-115 (free base)) 是一种ROCK 特异性抑制剂，能够抑制ROCK1和ROCK2的活性，IC50值分别为 51 和 19 nM。
T26078	Rhodblock 6 Rhodblock6,Rhodblock-6	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Rhodblock 6 是一种 Rho 激酶 (ROCK) 抑制剂，可抑制磷酸化 MRLC（肌球蛋白调节轻链）定位,通过特异性抑制 Rho 激酶的活性发挥作用。
T69665	Zelasudil RXC007	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Zelasudil (RXC007) 是一种 Rho 相关 (ROCK) 激酶抑制剂，可用于研究特发性肺纤维化和炎症。
T36196	CAY10746	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	CAY10746 是一种选择性 Rho 激酶 (ROCK) 抑制剂,对 ROCK I、ROCK II 具有抑制作用，IC50 值分别为 0.014 μM 和 0.003 μM。CAY10746 可用于研究糖尿病和视网膜病变。
T10358	Netarsudil Dihydrochloride AR-13324 Dihydrochloride	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) 是 Rho 相关蛋白激酶 (ROCK) 和去甲肾上腺素转运蛋白 (NET) 的抑制剂，可有效降低眼压 (IOP)。
T35328	H-1152 dihydrochloride H-1152 2HCl,H-1152 dihydrochloride	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	H-1152 dihydrochloride (H-1152 2HCl) 是 Rho 相关蛋白激酶 (ROCK) 的特异性抑制剂，IC50 为 12 nM，Ki 为 1.6 nM。 H-1152 dihydrochloride 抑制 PKA、PKC、PKG、Aurora A 和 CaMKII，IC50 值分别为 3.03 μM、5.68 μM、0.360 μM、0.745 μM 和 0.180 μM。
T60924	Verosudil AR-12286	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Verosudil (AR-12286) 是一种高效的 Rho 激酶 (ROCK) 抑制剂，对 ROCK1 和 ROCK2 的 Ki 分别为 2 和 2 nM。AR-12286 可逆转类固醇诱导的小鼠眼内压，可通过增加眼房水通过小梁网流出来减缓眼压。
T24722	ROCK-IN-32 ROCK-inhibitor-32,ROCK inhibitor 32	Others	Others
	ROCK-IN-32 is an effective Rho-kinase inhibitor.
T69132	NSC-4231	Others	Others
	NSC-4231 is a novel Rho-Kinase-II Inhibitor with Vasodilatory Activity.
T28387	PF-4950834 PF 4950834,PF4950834	Others	Others
	PF-4950834, a ATP-competitive, selective Rho kinase inhibitor, provides therapeutic benefits in chronic inflammatory diseases.
T30121	ARC-3002 ARC3002	Others	Others
	ARC-3002 is a highly potent and selective fluorescent probe of Rho kinase (ROCK).
T71106	Cotosudil 2HCl	Others	Others
	Cotosudil 2HCl is the salt form of Cotosudil Free Base, a Rho-associated (ROCK) kinase inhibitor.
T16855	SB-772077B dihydrochloride	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	SB-772077B dihydrochloride is an aminofurazan-based Rho kinase inhibitor (IC50s: 5.6 nM and 6 nM toward ROCK1 and ROCK2, respectively).
T10358L2	Netarsudil mesylate AR-13324 (mesylate)	Others	Others
	Netarsudil mesylate is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.
T69142	NSC-2888	Others	Others
	NSC-2888 is a Novel Rho-Kinase-II Inhibitor with Vasodilatory Activity.
T69123	NSC-2488	Others	Others
	NSC-2488 is a novel Rho-Kinase-II Inhibitor with Vasodilatory Activity.

化合物

Rho-Kinase-IN-1

Cat.No: T12721

Target: ROCK

Cat.No: T2633

Synonym: RHO-15

Target: ROCK

Cat.No: T7391

Target: ROCK, Rho

Cat.No: T14960

Target: ROCK

Cat.No: T2155

Target: ROCK

ROCK inhibitor-2

Cat.No: T12746

Target: ROCK

Cat.No: T7301

Target: ROCK

Cat.No: T3513

Synonym: GSK180736

Target: ROCK, GRK, PKA

Cat.No: T14989

Target: ROCK, GRK, PKC

Afuresertib hydrochloride

Cat.No: T7885

Target: ROCK, Akt, PKC

Cat.No: T4095

Synonym: ROCK inhibitor

Target: ROCK

Cat.No: T15798

Target: ROCK, LIM Kinase, PKA

Cat.No: T4488

Synonym: GSK25

Target: ROCK, S6 Kinase, mTOR

Cat.No: TQ0187

Target: ROCK, Autophagy

Cat.No: T12747

Target: ROCK

Cat.No: T1898

Synonym: RKI1447

Target: ROCK

Cat.No: T1870

Target: ROCK, Apoptosis

Cat.No: T7648

Target: Myosin, PKA, PKC

Cat.No: T2011

Synonym: RKI 1313,RKI-1313

Target: ROCK

Cat.No: T2482

Target: ROCK, SGK, Akt, PKA, S6 Kinase

Cat.No: T7764

Target: ROCK, Rho, Ras

Cat.No: T1911

Synonym: GSK2110183C,GSK2110183

Target: ROCK, Akt, PKC

Cat.No: T6867

Synonym: KD025,Rezurock,ROCK inhibitor,SLx-2119

Target: ROCK

Y-33075 dihydrochloride

Cat.No: T13384L

Target: CaMK, ROCK, PKC

SAR407899 hydrochloride

Cat.No: T23308

Synonym: 6-(哌啶-4-氧基)异喹啉-1(2H)-酮盐酸盐

Target: ROCK

Cat.No: TQ0110

Synonym: TC-S 7001,Azaindole 1

Target: ROCK

Cat.No: T4276L

Synonym: Hydroxy-Fasudil,HA-1100,羟基法舒地尔

Target: ROCK, PKA

Cat.No: T3518

Synonym: GSK269962B,GSK 269962,GSK269962A HCl

Target: ROCK, S6 Kinase

Hydroxyfasudil Hydrochloride

Cat.No: T4276

Synonym: Hydroxyfasudil (HA-1100) HCl,羟基法舒地尔盐酸盐,RHO-激酶抑制剂,HA 1100 hydrochloride

Target: ROCK

Cat.No: T1606

Synonym: HA-1077,AT877,法舒地尔

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

Y-27632 dihydrochloride

Cat.No: T1725

Synonym: 反式-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐,Y-27632 2HCl

Target: ROCK, Apoptosis

Fasudil hydrochloride

Cat.No: T3060

Synonym: Fasudil (HA-1077) HCl,盐酸法舒地尔,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Cat.No: T7552

Target: ROCK

Rho-Kinase-IN-2

Cat.No: T61497

Target: Others

Ripasudil free base

Cat.No: T7492

Synonym: K-115 (free base)

Target: ROCK, Antibacterial

Cat.No: T26078

Synonym: Rhodblock6,Rhodblock-6

Target: ROCK

Cat.No: T69665

Synonym: RXC007

Target: ROCK

Cat.No: T36196

Target: ROCK

Netarsudil Dihydrochloride

Cat.No: T10358

Synonym: AR-13324 Dihydrochloride

Target: ROCK

H-1152 dihydrochloride

Cat.No: T35328

Synonym: H-1152 2HCl,H-1152 dihydrochloride

Target: ROCK

Cat.No: T60924

Synonym: AR-12286

Target: ROCK

Cat.No: T24722

Synonym: ROCK-inhibitor-32,ROCK inhibitor 32

Target: Others

Cat.No: T69132

Target: Others

Cat.No: T28387

Synonym: PF 4950834,PF4950834

Target: Others

Cat.No: T30121

Synonym: ARC3002

Target: Others

Cat.No: T71106

Target: Others

SB-772077B dihydrochloride

Cat.No: T16855

Target: ROCK

Netarsudil mesylate

Cat.No: T10358L2

Synonym: AR-13324 (mesylate)

Target: Others

Cat.No: T69142

Target: Others

Cat.No: T69123

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TQ0183	Narciclasine 水仙环素,Lycoricidinol	ROCK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Narciclasine (Lycoricidinol) 是一种植物生长调节剂。它通过调节Rho/Rho 激酶/LIM 激酶/cofilin 信号传导途径，大大增加GTP 酶RhoA 活性以及以RhoA 依赖性方式诱导肌动蛋白应力纤维形成。
T4969	Guanosine 5'-triphosphate trisodium salt 鸟苷-5'-三磷酸三钠盐,GTP Trisodium salt,5'-GTP trisodium salt	Endogenous Metabolite	Metabolism
	Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) 为G蛋白(G proteins)信号转导过程中的活化剂。

天然产物

Cat.No: TQ0183

Synonym: 水仙环素,Lycoricidinol

Target: ROCK

Guanosine 5'-triphosphate trisodium salt

Cat.No: T4969

Synonym: 鸟苷-5'-三磷酸三钠盐,GTP Trisodium salt,5'-GTP trisodium salt

Target: Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03764	YAP1 Protein, Human, Recombinant (His) YAP1-2gamma,YAP2L,YAP65	Human	P. pastoris (Yeast)
	Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1,...
TMPY-01958	RhoA Protein, Human, Recombinant (His) ras homolog family member A,ARHA,RHO12,RHO...	Human	Baculovirus Insect Cells
	Transforming protein RhoA, also known as Rho cDNA clone 12, Ras homolog gene family member A, RHOA and ARH12, is a cell membrane and cytoplasm protein that belongs to the small GTPase superfamily and Rho family. The Rho family of small GTPases plays a key role in the dynamic regulation of the actin cytoskeleton that underlies various important cellular functions such as shape changes, migration, and polarity. RHOA / ARH12 is part of a larger family of related proteins known as the Ras superfamil...
TMPY-04397	PAK-3 Protein, Human, Recombinant (His) PAK3β,hPAK3,bPAK,PAK3beta,MRX30,MRX47,CDKN1A,p21 protein (Cd...	Human	Baculovirus Insect Cells
	PAK3 is a member of PAK proteins, a family of serine/threonine p21-activating kinases, serve as effectors of small Rho GTPases Cdc42 and RAC and have been implicated in a wide range of biological activities. There are six mammalian PAKs which can be divided into two groups: group I PAKs (PAK1-3) and group II PAKs (PAK4-6). Although the two PAK groups are architecturally similar there are differences in their mode of regulation suggesting their cellular functions are likely to be different. Group...

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YAP1 Protein, Human, Recombinant (His)

Cat.No: TMPH-03764

Species: Human

Expression System: P. pastoris (Yeast)

RhoA Protein, Human, Recombinant (His)

Cat.No: TMPY-01958

Species: Human

Expression System: Baculovirus Insect Cells

PAK-3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04397

Species: Human

Expression System: Baculovirus Insect Cells

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