10
5
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T25158 |
Bishomoreserpine
Reserpic acid |
Others | Others |
Bishomoreserpine is a reserpine analog with a potent inhibitory. | |||
T30595 |
Bromoreserpine
|
Others | Others |
Bromoreserpine 是 reserpine的类似物。 | |||
T31426 |
Dibromoreserpine
|
Others | Others |
Dibromoreserpine is a biochemical. | |||
T32228 |
Isoreserpine
NSC 80138 |
Others | Others |
Isoreserpine is a biochemical. | |||
T0218 |
Biperiden
Bipariden,Akineton,KL 373,比哌立登,Biperidine |
AChR | Neuroscience |
Biperiden (Bipariden) 是中枢 M1胆碱受体阻断剂,有抗帕金森症活性。 | |||
T29193 |
Yohimbic acid, ethyl ester
|
Others | Others |
Yohimbic acid, ethyl ester is a biochemical with possible effects on reserpine action. | |||
T25576 |
KF 392
KF392,KF-392 |
Others | Others |
KF 392 is antiulcer. It was found that KF-392 given orally to rats at 1.0 to 5.0 mg/kg had a marked suppression on the developments of Shay ulcer as well as the aspirin-, stress-, and reserpine-induced gastric lesions. | |||
T71787 |
Deserpidine hydrochloride
|
Others | Others |
Deserpidine hydrochloride is the salf form of Deserpidine (free base), which is an antihypertensive drug related to reserpine which occurs naturally in Rauwolfia canescens. Deserpidine is a competitive inhibitor of the angiotensin converting enzyme (ACE). By competing with angiotensin I for ACE, deserpidine blocks the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor. Reduced level of serum angiotensin II causes a decrease in blood pressure. Deserpidine also decrea... | |||
T68803 |
Perafensine
|
Others | Others |
Perafensine is a drug which was investigated as an antidepressant but was never marketed. It has been reported to antagonize the effects of reserpine and to inhibit the reuptake of norepinephrine (norepinephrine reuptake inhibitor); whether it also affects the reuptake of serotonin or dopamine is unclear | |||
T84941 |
(±)-N-desmethyl Venlafaxine hydrochloride
Wy 45494 |
Others | Others |
(±)-N-desmethyl Venlafaxine, a minor active metabolite of venlafaxine, serves as a selective norepinephrine and serotonin reuptake inhibitor (SNRI). Generated through the metabolization by the cytochrome P450 (CYP) isoform CYP3A4, it exhibits reuptake inhibition of norepinephrine and serotonin in rat synaptosome preparations, demonstrated by IC50 values of 4.7 and 1.6 µM, respectively. Clinically, it has been shown to counteract reserpine-induced hypothermia in mice, displaying efficacy at a min... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0791 |
Reserpine
利血平,Serpalan,Serpasil,Serpivite |
Others; Potassium Channel; MRP; Monoamine Transporter; Autophagy | Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Others |
Reserpine (Serpalan) 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中,导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。 | |||
T21772 |
Reserpine hydrochloride
|
||
Reserpine hydrochloride 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中,导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。 | |||
T8270 |
Deserpidine
地舍平,Harmonyl |
RAAS | Endocrinology/Hormones |
Deserpidine (Harmonyl) 是从 Rauwolfia canescens 的根中分离的生物碱。Deserpidine 与 Reserpine 相关。Deserpidine 是竞争性血管紧张素转化酶抑制剂,可以被用作抗高血压药以及镇定剂。Deserpidine 还减少了肾上腺皮质血管紧张素 II 诱导的醛固酮分泌。 | |||
T1379 |
L-5-Hydroxytryptophan
5-羟基色氨酸,L-oxitriptan,Oxitriptan,L-5-HTP |
Amino Acids and Derivatives; Endogenous Metabolite | Metabolism |
L-5-Hydroxytryptophan (L-5-HTP) 是一种天然氨基酸和膳食补充剂,可以用作抗抑郁剂、食欲抑制剂和睡眠辅助剂,是神经递质血清素的前体,是利血平(reserpine) 的拮抗剂。它能够用于肌阵挛、纤维肌痛症、偏头痛和小脑共济失调的研究。 | |||
TN4319 |
Isopimaric acid
|
Antifection | Microbiology/Virology |
Isopimaric acid is active against MDR and MRSA strains of S. aureus which are becoming increasingly resistant to antibiotics, the minimum inhibitory concentrations (MIC) are 32-64 microg/mL . Isopimaric acid is also possible that an antagonistic interacti |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMID-0075 |
Reserpine-d9
|
||
Reserpine-d9 是 Reserpine 的氘代化合物。Reserpine 的 CAS 号为 50-55-5。Reserpine 是一种从催吐萝芙木的根中发现的生物碱。它抑制去甲肾上腺素吸收到储存囊泡中,导致中枢和外周轴突末端的儿茶酚胺和血清素耗尽。它可作为抗高血压药和抗精神病药以及研究工具。 |