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Search Results for " ror "

Targets Recommended: Aurora Kinase ROR Others

93

抑制剂 & 化合物

23

天然产物

21

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T24727	ROR Modulator I ROR-Modulator-I,RORModulatorI	Others	Others
	ROR Modulator I is the first potent inverse agonist of the retinoid-related orphan receptor. It also has dual selectivity for RORβ and RORγt.
T4050	GSK2981278 ROR gama modulator 1	ROR	Metabolism
	GSK2981278 (ROR gama modulator 1) 是 RORγ的选择性反向激动剂。它能够抑制 il17启动子的激活，并且干扰 RORγ-DNA 结合。
T12750	ROR agonist-1	Others	Others
	ROR agonist-1 is a potent and orally bioavailable the retinoic acid receptor-related orphan receptor C2 (RORC2) inverse agonist(inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5).
T12753	RORγt Inverse agonist 6	ROR	Metabolism
	RORγt Inverse agonist 6 是 RORγt inverse 的激动剂。 RORγt Inverse agonist 6 可用于研究 Th17 驱动的自身免疫性疾病。
T9623	RORγt inverse agonist 13	ROR	Metabolism
	RORγt inverse agonist 13 是一种口服有效的RORγt 选择性反向激动剂，IC50为 63.8 nM。
T39250	Bevurogant	ROR	Metabolism
	Bevurogant 是 RORγt 受体的拮抗剂，可用于治疗慢性炎症性疾病的研究。
T67943	RORγ inverse agonist 1	Others	Others
	RORγ inverse agonist 1具有抗炎活性，可用来治疗风湿和银屑病。
T4670	SR0987	ROR	Metabolism
	SR0987是SR1078 的类似物，是RORγt 的激动剂，其EC50=800 nM。它可上调IL17 的表达，并且抑制PD-1 的表达。
T5163	SR1001	ROR	Metabolism
	SR1001 是选择性RORα及RORγt 的反向激动剂，其Ki 分别为 172 和 111 nM。
TQ0007	Cintirorgon LYC-55716	ROR	Metabolism
	Cintirorgon (LYC-55716) 是一种首创的、口服有活力的的RORγ选择性激动剂。它通过调节 RORγ 表达的 T 淋巴免疫细胞的基因表达，提高效应子功能，降低免疫抑制，抑制肿瘤生长，提高生存率。
T4594	SR1078 SR 1078	ROR	Metabolism
	SR1078 是视黄酸受体相关孤儿受体 (RORα/RORγ) 激动剂。它能够与 RORα 和 RORγ 的配体结合区直接结合，增强该受体的转录活性，促使 RORα/γ 靶基因的转录。
T7388	GSK805	ROR	Metabolism
	GSK805 是能够生物利用的、具有 CNS 穿透性的 RORγt 抑制剂。
T9635	Cedirogant ABBV-157	ROR	Metabolism
	Cedirogant (ABBV-157) 是一种口服有活性的 RORγt 反向激动剂，可用于研究银屑病。
T5160	SR3335 ML 176	ROR	Metabolism
	SR3335 (ML 176) 是特异性RORα反向激动剂，能够与 RORα直接结合，其Ki=220 nM。
T16832	S18-000003	ROR	Metabolism
	S18-000003 是口服有活性的维甲酸相关孤儿受体 (RORγt) 选择性抑制剂，在竞争性结合试验中，对 hRORγt 的 IC50值小于 30 nM。它对 RORγt 的选择性比其他 ROR 家族成员 (IC50>10 μM)更高。它可用于银屑病的研究，胸腺畸变风险较低。
T14369	AZD-0284	ROR	Metabolism
	AZD-0284 是核受体 (RORγ) 的选择性反向激动剂。它对呼吸道疾病及斑块型寻常型银屑病具有潜在的应用价值。
T39797	RORγ agonist 1	Others	Others
	RORγ agonist 1 is a highly potent and orally bioavailable compound that activates the RORγ receptor. Its efficacy is demonstrated by an EC50 value of 21 nM and it exhibits antitumor activity.
T39038	RORγt inhibitor 1	Others	Others
	RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC 50 value of 1 nM.
TMAZ-0111A	Anti-ROR2 Monoclonal Antibody-APC
	Anti-ROR2 Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting ROR2. Anti-ROR2 Monoclonal Antibody-APC can be used ELISA, FACS.
TMAZ-0111B	Anti-ROR2 Monoclonal Antibody-Biotin
	Anti-ROR2 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting ROR2. Anti-ROR2 Monoclonal Antibody-Biotin can be used ELISA, FACS.
T40043	RORγt Inverse agonist 10	Others	Others
	RORγt Inverse agonist 10 is a highly potent and orally bioavailable compound that acts as an antagonist for the retinoic acid receptor-related orphan nuclear receptor gamma t (RORγt). With an IC50 of 51 nM, it effectively inhibits the activity of RORγt, a prominent transcription factor involved in the regulation of genes associated with the pathogenesis of psoriasis, including IL-17A, IL-22, and IL-23R.
T39720	RORγt inverse agonist 23	Others	Others
	RORγt inverse agonist 23, an orally available novel retinoic acid receptor-related orphan receptor γt inverse agonist, is a potent and selective RORγt inverse agonist.
TMAZ-0111P	Anti-ROR2 Monoclonal Antibody-PE
	Anti-ROR2 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting ROR2. Anti-ROR2 Monoclonal Antibody-PE can be used ELISA, FACS.
TMAZ-0111A5	Anti-ROR2 Monoclonal Antibody-AF555
	Anti-ROR2 Monoclonal Antibody-AF555 is a biotin-conjugated humanized rabbit antibody targeting ROR2. Anti-ROR2 Monoclonal Antibody-AF555 can be used ELISA, FACS.
TMAZ-0111A6	Anti-ROR2 Monoclonal Antibody-AF647
	Anti-ROR2 Monoclonal Antibody-AF647 is a biotin-conjugated humanized rabbit antibody targeting ROR2. Anti-ROR2 Monoclonal Antibody-AF647 can be used ELISA, FACS.
T79464	RORγ antagonist 1	ROR	Metabolism
	RORγ antagonist1 (化合物22) 作为RORγ的有效拮抗剂 (KD=0.18 μM)，在HPAF-II胰腺癌异种移植模型中显示出了抗增殖性能。该化合物通过抑制RAS/MAPK和AKT/mTORC1通路，并引发caspase依赖的细胞凋亡(apoptosis)机制，从而在胰腺癌细胞中发挥作用。
T63678	RORγt modulator 2	Others	Others
	RORγt modulator 2 是一种类视黄醇相关孤儿受体 γt (RORyt) 的调节剂 (IC50<50 nM)，能够用于 RORγt 介导的疾病的研究，如疼痛、炎症、哮喘、类风湿性关节炎、COPD、多发性硬化、银屑病、结肠炎、神经退行性疾病和癌症。
T63124	RORγt modulator 4	Others	Others
	RORγt modulator 4 是一种 RORγt 调节剂。RORγt modulator 4 能够调节源自小鼠脾脏的细胞中 IL-17A 产生的活性。
T72596	RORγt modulator 5	Others	Others
	RORγt modulator 5 是一种 RORγt 调节剂，Ki 值 <100 nM。RORγt modulator 5 可用于研究 RORy 介导的炎症、代谢、自身免疫和其他疾病。
T63609	RORγt modulator 3	Others	Others
	RORγt modulator 3 是一种类视黄醇相关孤儿受体 γt (RORγt) 的调节剂，能够用于研究 RORγt 介导的疾病，如疼痛、COPD、炎症、哮喘、结肠炎、多发性硬化、类风湿性关节炎、银屑病、神经退行性疾病和癌症。
T72595	RORγt inhibitor 2	Others	Others
	RORγt inhibitor 2 是一种有效的RORγt 抑制剂，IC50为 9.2 nM。RORγt inhibitor 2可用于研究由RORγt 介导的癌症、炎症或自身免疫性疾病。
T63874	RORγt inverse agonist 28	Others	Others
	RORγt inverse agonist 28 是有效的 RORγt 反向激动剂。RORγt inverse agonist 28 能够调节 Th17 细胞的分化，并抑制 IL-17 的产生。RORγt inverse agonist 28 对炎症和自身免疫性疾病表现出研究潜力。
T64145	RORγt/DHODH-IN-1	Others	Others
	RORγt/DHODH-IN-1 (compound (R)-14d) 是一种有效的、口服具有活力 RORγt (IC50: 0.083 μM) 和 DHODH (IC50: 0.172 μM) 的双重抑制剂。RORγt/DHODH-IN-1 具有明显的体内抗炎作用。
T6690	T0901317 N-(2,2,2-三氟乙基)-N-[4-[2,2,2-三氟-1-羟基-1-(三氟甲基)乙基]苯基]苯磺酰胺	Apoptosis; FXR; Liver X Receptor; ROR	Apoptosis; Metabolism
	T0901317 是一种口服有效且高度选择性的LXR 激动剂，对 LXRα 的EC50为 20 nM。它激活FXR，EC50为 5 μM。它是RORα和RORγ双重反向激动剂，Ki 值分别为 132 nM 和 51 nM。它诱导细胞凋亡，并抑制低密度脂蛋白受体缺失小鼠动脉粥样硬化的发展。
T79470	RORγt inverse agonist 31	ROR	Metabolism
	RORγt inverse agonist 31 (14g) 为一有效RORγt反向激动剂，具备0.428 μM的IC50值。该化合物能够缓解Imiquimod诱发的小鼠牛皮癣症状。
T62564	RORγt inverse agonist 30	Others	Others
	RORγt inverse agonist 30 (Compound 1) 是一种有效的 RORγt 反向激动剂 (IC50: 46 nM)。靶向核受体 RORγt 能够有效治疗自身免疫性疾病。
T64146	RORγt/DHODH-IN-3	Others	Others
	RORγt/DHODH-IN-3 (compound (S)-14d) 是一种有效的、口服具有活力 RORγt (IC50: 0.098 μM) 和 DHODH (IC50: 0.432 μM) 的双重抑制剂。RORγt/DHODH-IN-1 具有明显的体内抗炎作用。
T72254	RORγt inverse agonist 26	Others	Others
	RORγt inverse agonist 26 是一种有效的 RORγt 反向激动剂。RORγt inverse agonist 26 调节 Th17 细胞的分化并抑制 IL-17的产生。RORγt inverse agonist 26 具有研究炎症和自身免疫性疾病的潜力。
T62462	RORγt/DHODH-IN-2	Others	Others
	RORγt/DHODH-IN-2 (compound 1) 是一种有效的 RORγt/DHODH 双重抑制剂，能够用于研究炎症性肠病 (IBD)。
T64017	RORγt agonist 3	Others	Others
	RORγt agonist 3 是 RORγt 的有效激动剂。RORγt agonist 3 能够促使 Th17 细胞分化，增加促炎细胞因子水平，进而提高淋巴细胞的细胞毒性。RORγt agonist 3 能够阻碍调节性 T 细胞的产生，并免疫反应产生抑制作用。
T64140	RORγt agonist 2	Others	Others
	RORγt agonist 2 是 RORγt 的有效的激动剂。RORγt agonist 2 能够诱导 Th17 细胞分化，增加促炎细胞因子水平，进而增强淋巴细胞的细胞毒性。RORγt agonist 2 对调节性 T 细胞的产生表现出抑制作用，能够抑制免疫反应。
TMAZ-0111A4	Anti-ROR2 Monoclonal Antibody-AF488
	Anti-ROR2 Monoclonal Antibody-AF488 is a biotin-conjugated humanized rabbit antibody targeting ROR2. Anti-ROR2 Monoclonal Antibody-AF488 can be used ELISA, FACS.
T72252	RORγt inverse agonist 14	ROR	Metabolism
	RORγt inverse agonist 14 (8e) 是一种高效、口服活性及选择性 RORγt 反向激动剂（EC50 为 2.5 nM），具有抗炎作用，主要应用于风湿性关节炎和牛皮癣的研究。
T62956	RORγt inverse agonist 29	Others	Others
	RORγt inverse agonist 29 是一种有效的、选择性的、口服具有活力的 RORγt 反向激动剂，其 IC50 值为 21 nM。RORγt inverse agonist 29 能够用于皮肤炎症和银屑病等自身免疫性疾病的研究。
T5520L	Cetrorelix diacetate NS-75A,醋酸西曲瑞克,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate	GNRH Receptor	GPCR/G Protein
	Cetrorelix diacetate (NS-75A) 是GnRH 受体的强效拮抗剂(IC50:1.21 nM)。
T17174	Troriluzole BHV4157,BHV-4157,BHV-4157a,FC 4157,BHV 4157	transporter	Metabolism
	Troriluzole 是一种具有口服活性谷氨酸调节剂，具有抗癌活性。Troriluzole 可提高位于神经胶质细胞的兴奋性氨基酸转运体的表达，可用于研究脊髓小脑性共济失调、阿尔茨海默病和广泛性焦虑症 (GAD) 。
T5520	Cetrorelix Acetate 醋酸西曲瑞克,Cetrorelix	GNRH Receptor	GPCR/G Protein
	Cetrorelix Acetate 是一种GnRH 受体的强效拮抗剂(IC50:1.21 nM)。
T61093	MicroRNA-21-IN-2	Others	Others
	microRNA-21-IN-2，一种潜在的miR-21抑制剂，其AC50值为3.29 μM，主要用于癌症研究。
T5524	Aurora kinase inhibitor-3 Aurora Kinase Inhibitor III	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) 是一种有效的，选择性 Aurora A 激酶抑制剂，IC50为 42 nM。
T12010	Aurora B inhibitor 1	Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic
	Aurora B inhibitor 1 是一种 Aurora B (Aurora-1) 抑制剂（Ki <0.010 uM），具有潜在的抗癌活性，可用于研究癌症。

化合物

ROR Modulator I

Cat.No: T24727

Synonym: ROR-Modulator-I,RORModulatorI

Target: Others

Cat.No: T4050

Synonym: ROR gama modulator 1

Target: ROR

ROR agonist-1

Cat.No: T12750

Target: Others

RORγt Inverse agonist 6

Cat.No: T12753

Target: ROR

RORγt inverse agonist 13

Cat.No: T9623

Target: ROR

Cat.No: T39250

Target: ROR

RORγ inverse agonist 1

Cat.No: T67943

Target: Others

Cat.No: T4670

Target: ROR

Cat.No: T5163

Target: ROR

Cat.No: TQ0007

Synonym: LYC-55716

Target: ROR

Cat.No: T4594

Synonym: SR 1078

Target: ROR

Cat.No: T7388

Target: ROR

Cat.No: T9635

Synonym: ABBV-157

Target: ROR

Cat.No: T5160

Synonym: ML 176

Target: ROR

Cat.No: T16832

Target: ROR

Cat.No: T14369

Target: ROR

RORγ agonist 1

Cat.No: T39797

Target: Others

RORγt inhibitor 1

Cat.No: T39038

Target: Others

Anti-ROR2 Monoclonal Antibody-APC

Cat.No: TMAZ-0111A

Anti-ROR2 Monoclonal Antibody-Biotin

Cat.No: TMAZ-0111B

RORγt Inverse agonist 10

Cat.No: T40043

Target: Others

RORγt inverse agonist 23

Cat.No: T39720

Target: Others

Anti-ROR2 Monoclonal Antibody-PE

Cat.No: TMAZ-0111P

Anti-ROR2 Monoclonal Antibody-AF555

Cat.No: TMAZ-0111A5

Anti-ROR2 Monoclonal Antibody-AF647

Cat.No: TMAZ-0111A6

RORγ antagonist 1

Cat.No: T79464

Target: ROR

RORγt modulator 2

Cat.No: T63678

Target: Others

RORγt modulator 4

Cat.No: T63124

Target: Others

RORγt modulator 5

Cat.No: T72596

Target: Others

RORγt modulator 3

Cat.No: T63609

Target: Others

RORγt inhibitor 2

Cat.No: T72595

Target: Others

RORγt inverse agonist 28

Cat.No: T63874

Target: Others

RORγt/DHODH-IN-1

Cat.No: T64145

Target: Others

Cat.No: T6690

Synonym: N-(2,2,2-三氟乙基)-N-[4-[2,2,2-三氟-1-羟基-1-(三氟甲基)乙基]苯基]苯磺酰胺

Target: Apoptosis, FXR, Liver X Receptor, ROR

RORγt inverse agonist 31

Cat.No: T79470

Target: ROR

RORγt inverse agonist 30

Cat.No: T62564

Target: Others

RORγt/DHODH-IN-3

Cat.No: T64146

Target: Others

RORγt inverse agonist 26

Cat.No: T72254

Target: Others

RORγt/DHODH-IN-2

Cat.No: T62462

Target: Others

RORγt agonist 3

Cat.No: T64017

Target: Others

RORγt agonist 2

Cat.No: T64140

Target: Others

Anti-ROR2 Monoclonal Antibody-AF488

Cat.No: TMAZ-0111A4

RORγt inverse agonist 14

Cat.No: T72252

Target: ROR

RORγt inverse agonist 29

Cat.No: T62956

Target: Others

Cetrorelix diacetate

Cat.No: T5520L

Synonym: NS-75A,醋酸西曲瑞克,SB-075 acetate,SB-075 diacetate,Cetrorelix acetate,NS-75A diacetate

Target: GNRH Receptor

Cat.No: T17174

Synonym: BHV4157,BHV-4157,BHV-4157a,FC 4157,BHV 4157

Target: transporter

Cetrorelix Acetate

Cat.No: T5520

Synonym: 醋酸西曲瑞克,Cetrorelix

Target: GNRH Receptor

MicroRNA-21-IN-2

Cat.No: T61093

Target: Others

Aurora kinase inhibitor-3

Cat.No: T5524

Synonym: Aurora Kinase Inhibitor III

Target: Aurora Kinase

Aurora B inhibitor 1

Cat.No: T12010

Target: Aurora Kinase

Cat. No.	Product Name	Target	Signaling Pathways
T3S1251	Neoruscogenin	ROR	Metabolism
	Neoruscogenin 是甾体 sapogenin 家族的成员，是一种可生物利用且具有高亲和力的核受体RORα (NR1F1)激动剂。
T2834	Nobiletin Hexamethoxyflavone,川陈皮素,川皮苷	Apoptosis; MMP; Reactive Oxygen Species; ROR; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome
	Nobiletin (Hexamethoxyflavone) 是一种来自柑橘皮的聚甲氧基黄酮，是RORs 激动剂，可改善记忆力丧失。它可降低分化的 C2C12 肌管中的ROS 水平，并具有抗炎，抗癌，抗血管生成，抗增殖，抗转移和诱导细胞凋亡作用。
T1079	Metronidazole Flagyl,Metronidazol,甲硝唑,Anagiardil	Apoptosis; NADPH; Hydrogenase; Antibacterial; Antibiotic; Parasite; Antifection	Apoptosis; Metabolism; Microbiology/Virology
	Metronidazole (Metronidazol) 是一种合成的硝基咪唑衍生物，一种抗生素和抗原虫剂，具有口服活性和血脑屏障渗透性。Metronidazole 可用于治疗或预防厌氧菌引起的系统或局部感染。
T13502	3-Oxo-5β-cholanoic acid 3-氧代-5β-胆烷酸,Dehydrolithocholic acid	ROR	Metabolism
	3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) 是胆汁酸的一种代谢产物。3-Oxo-5β-cholanoic acid 直接与关键转录因子RORγt(Kd=1.13 μM) 结合抑制TH17细胞分化。
T3933	Jatrorrhizine Yatrorizine,neprotin,药根碱	MAO; 5-HT Receptor; Antibacterial; AChE	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Jatrorrhizine (neprotin) 是一种从黄连中分离得到的生物碱，具有抗菌、抗氧化、抗疟原虫和神经保护活性。它通过抑制 uptake-2 transporter 的活性减少血清素和去甲肾上腺素的摄取。它是一种有口服活性的乙酰胆碱酯酶制剂。
T4912	Jatrorrhizine chloride 盐酸药根碱,Yatrorhizine chloride,Neprotine chloride	Others; 5-HT Receptor; OCT; Antibacterial; AChE	GPCR/G Protein; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others
	Jatrorrhizine chloride (Neprotine chloride) 是从黄连中分离得到的生物碱，具有神经保护、抗菌、抗氧化和抗疟原虫活性。它通过抑制摄取2转运蛋白的活性减少血清素和去甲肾上腺素的摄取。它是具有口服活性的乙酰胆碱酯酶抑制剂。
T3840	Dihydroresveratrol 3,4',5-Trihydroxybibenzyl,二氢白藜芦醇,二氢藜芦醇	Estrogen Receptor/ERR; Others	Endocrinology/Hormones; Others
	Dihydroresveratrol (3,4',5-Trihydroxybibenzyl) 是一种激素受体调节剂，是一种植物雌激素。它在皮摩尔和纳摩尔浓度下促进前列腺和乳腺癌细胞增殖。
TN1586	Dihydrorotenone	Apoptosis; Mitochondrial Metabolism	Apoptosis; Metabolism
	Dihydrorotenone 是一种线粒体抑制剂，是天然杀虫剂。它通过触发内质网应激并激活 p38 信号通路来诱导人浆细胞凋亡，可能诱发帕金森综合症。
T37009	Oxychlororaphine 吩嗪-1-甲酰胺,phenazine-1-carboxamide	Antibacterial	Microbiology/Virology
	Oxychlororaphine (phenazine-1-carboxamide) 强烈抑制 Streptomyces sp. 411 的生长。
T2986	Jatrorrhizine hydrochloride	Others; 5-HT Receptor; Antibacterial; AChE	GPCR/G Protein; Microbiology/Virology; Neuroscience; Others
	Jatrorrhizine hydrochloride 是从小檗的根中提取的化合物，具有具有神经保护、抗菌、抗疟原虫和抗氧化活性。Jatrorrhizine hydrochloride 是一种具有口服活性和选择性的乙酰胆碱酯酶 (AChE)抑制剂，抑制去甲肾上腺素 (NE) 的摄取。
T41264	Roridin L2	Others	Others
	Roridin L2 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 T41264，CAS号为 85124-22-7。
TN6425	Saprorthoquinone
	Saprorthoquinone is a natural product from Salvia prionitis.
T80004	Tetrahydrorhombifoline	Others	Others
	TetraHydrorhombifoline为Genista vuralii A. Duran & H. Dural 地上部分所含喹啉西啶类生物碱。G. vuralii 生物碱提取物显示出抗菌与抗真菌作用。
T32198	Retrorsine N-oxide Isatidine	Others	Others
	Isatidine is a pyrrolizidine alkaoid.
TN7556	Cannabigerorcinic Acid Cannabigerorcinolic Acid,CBGOA,Cannabiorcogerolic Acid	Others	Others
	Cannabigerorcinic acid, structurally akin to recognized phytocannabinoids, serves as an analytical reference standard designed for research and forensic purposes.
TN1360	Afrormosine	Others	Others
	Afrormosine is a natural product
T34389	Rorifone 10-(Methylsulfonyl)decanenitrile
	Rorifone is a biochemical.
TN2147	Retrorsine	P450; OCT	Membrane transporter/Ion channel; Metabolism
	Retrorsine 特异性地抑制肝细胞增殖，并在肝损伤后唤起小肝细胞样祖细胞。逆转录酶可用于肝细胞损伤的研究。
TMA0600	Dihydrorobinetin	Others	Others
	(+)-Dihydrorobinetin is reported as a chemical marker of vinegars aged in acacia wood and can be used for authenticity purposes.
TN7510	all-trans-13,14-Dihydroretinol	Others	Others
	All-trans-13,14-Dihydroretinol, a metabolite of all-trans-retinoic acid, is synthesized through the enzymatic action of retinol saturase on all-trans-retinoic acid.
TN7558	Cannabigerorcin Cannabiorcogerol,Cannabigerorcinol,CBGO	Others	Others
	Cannabigerorcin, a phytocannabinoid, serves as an analytical reference standard. It is designated for research and forensic applications.
TN3864	Dihydroresveratrol 3-O-glucoside	Others	Others
	Dihydroresveratrol 3-O-glucoside 是一种天然产物，存在于Camellia sinensis var. assamica (J.W. Mast.) Kitam.叶子。
T75436	Jatrorrhizine hydroxide	Others	Others
	Jatrorrhizine hydroxide, 一种从黄连中提取的生物碱，展现了神经保护、抗菌、抗疟原虫及抗氧化的活性。作为一种高效的乙酰胆碱酯酶(AChE)抑制剂(IC50=872 nM)，其对BuChE的选择性高达115倍。此外，Jatrorrhizine hydroxide还能通过抑制uptake-2 transporter活性来减少血清素(5-HT)和去甲肾上腺素(NE)的摄取，表现出口服活性。

天然产物

Cat.No: T3S1251

Target: ROR

Cat.No: T2834

Synonym: Hexamethoxyflavone,川陈皮素,川皮苷

Target: Apoptosis, MMP, Reactive Oxygen Species, ROR, Autophagy

Cat.No: T1079

Synonym: Flagyl,Metronidazol,甲硝唑,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

3-Oxo-5β-cholanoic acid

Cat.No: T13502

Synonym: 3-氧代-5β-胆烷酸,Dehydrolithocholic acid

Target: ROR

Cat.No: T3933

Synonym: Yatrorizine,neprotin,药根碱

Target: MAO, 5-HT Receptor, Antibacterial, AChE

Jatrorrhizine chloride

Cat.No: T4912

Synonym: 盐酸药根碱,Yatrorhizine chloride,Neprotine chloride

Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE

Dihydroresveratrol

Cat.No: T3840

Synonym: 3,4',5-Trihydroxybibenzyl,二氢白藜芦醇,二氢藜芦醇

Target: Estrogen Receptor/ERR, Others

Dihydrorotenone

Cat.No: TN1586

Target: Apoptosis, Mitochondrial Metabolism

Oxychlororaphine

Cat.No: T37009

Synonym: 吩嗪-1-甲酰胺,phenazine-1-carboxamide

Target: Antibacterial

Jatrorrhizine hydrochloride

Cat.No: T2986

Target: Others, 5-HT Receptor, Antibacterial, AChE

Cat.No: T41264

Target: Others

Saprorthoquinone

Cat.No: TN6425

Tetrahydrorhombifoline

Cat.No: T80004

Target: Others

Retrorsine N-oxide

Cat.No: T32198

Synonym: Isatidine

Target: Others

Cannabigerorcinic Acid

Cat.No: TN7556

Synonym: Cannabigerorcinolic Acid,CBGOA,Cannabiorcogerolic Acid

Target: Others

Cat.No: TN1360

Target: Others

Cat.No: T34389

Synonym: 10-(Methylsulfonyl)decanenitrile

Cat.No: TN2147

Target: P450, OCT

Dihydrorobinetin

Cat.No: TMA0600

Target: Others

all-trans-13,14-Dihydroretinol

Cat.No: TN7510

Target: Others

Cannabigerorcin

Cat.No: TN7558

Synonym: Cannabiorcogerol,Cannabigerorcinol,CBGO

Target: Others

Dihydroresveratrol 3-O-glucoside

Cat.No: TN3864

Target: Others

Jatrorrhizine hydroxide

Cat.No: T75436

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00572	ROR1 Protein, Canine, Recombinant (His) dJ537F10.1,ROR1,NTRKR1	Canine	HEK293 Cells
	ROR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 52.2 kDa and the accession number is A0A8I3MPB6.
TMPK-00413	ROR1 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) ROR1,NTRKR1,dJ537F10.1	Human,Cynomolgus,Rhesus	HEK293 Cells
	ROR1 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 44.9 kDa and the accession number is Q01973-1.
TMPK-00579	ROR2 Protein, Human, Recombinant (hFc) BDB,NTRKR2,BDB1,ROR2	Human	HEK293 Cells
	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain. ROR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The...
TMPK-00577	ROR2 Protein, Human, Recombinant (His & Avi) NTRKR2,ROR2,BDB1,BDB	Human	HEK293 Cells
	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain. ROR2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Av...
TMPK-00566	ROR2 Protein, Cynomolgus, Recombinant (His) BDB,BDB1,NTRKR2,ROR2	Cynomolgus	HEK293 Cells
	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain. ROR2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag...
TMPK-00578	ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated BDB1,NTRKR2,ROR2,BDB	Human	HEK293 Cells
	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain. ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated is expressed in HEK293 mamm...
TMPY-04649	ROR1 Protein, Human, Recombinant (His) dJ537F10.1,NTRKR1,receptor tyrosine kinase-like orphan recep...	Human	HEK293 Cells
	ROR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa and the accession number is Q01973.
TMPY-05394	ROR2 Protein, Human, Recombinant (His) BDB,BDB1,NTRKR2,receptor tyrosine kinase-like orphan recepto...	Human	HEK293 Cells
	ROR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.8 kDa and the accession number is Q01974.
TMPH-01792	RORC Protein, Human, Recombinant (His & SUMO) Nuclear receptor subfamily 1 group F member 3,RAR-related or...	Human	E. coli
	RORC Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 74.2 kDa and the accession number is P51449.
TMPH-01791	RORA Protein, Human, Recombinant (His) Retinoid-related orphan receptor-alpha,Nuclear receptor ...	Human	E. coli
	RORA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 57.6 kDa and the accession number is P35398.
TMPY-04068	ROR1 Protein, Human, Recombinant (hFc) NTRKR1,dJ537F10.1,receptor tyrosine kinase-like orphan recep...	Human	HEK293 Cells
	ROR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69 kDa and the accession number is Q01973.
TMPY-06508	ROR1 Protein, Mouse, Recombinant (hFc) 2810404D04Rik,receptor tyrosine kinase-like orphan receptor ...	Mouse	HEK293 Cells
	ROR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 68.53 kDa and the accession number is NP_038873.2.
TMPY-06850	ROR2 Protein, Mouse, Recombinant (His) receptor tyrosine kinase-like orphan receptor 2,mRor	Mouse	HEK293 Cells
	ROR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.64 kDa and the accession number is Q9Z138.
TMPY-06103	ROR1 Protein, Mouse, Recombinant (His) Ntrkr1,receptor tyrosine kinase-like orphan receptor 1,m...	Mouse	HEK293 Cells
	ROR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.3 kDa and the accession number is Q9Z139.
TMPY-04986	ROR1 Protein, Human, Recombinant, Biotinylated receptor tyrosine kinase-like orphan receptor 1,NTRKR1,dJ537...	Human	HEK293 Cells
	ROR1 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 42.8 kDa and the accession number is Q01973.
TMPY-06825	ROR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated receptor tyrosine kinase-like orphan receptor 1,dJ537F10.1,N...	Human	HEK293 Cells
	ROR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 70.53 kDa and the accession number is NP_005003.2.
TMPY-05603	ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated dJ537F10.1,NTRKR1,receptor tyrosine kinase-like orphan recep...	Human	HEK293 Cells
	ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 45.2 kDa and the accession number is Q01973.
TMPY-05639	ROR2 Protein, Human, Recombinant (His & Avi), Biotinylated BDB,receptor tyrosine kinase-like orphan receptor 2,NTRKR2,B...	Human	HEK293 Cells
	ROR2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 44.6 kDa and the accession number is Q01974.
TMPY-04428	ROR1 Protein, Human, Recombinant (aa 453-783, His & GST) NTRKR1,receptor tyrosine kinase-like orphan receptor 1,dJ537...	Human	Baculovirus Insect Cells
	ROR1 Protein, Human, Recombinant (aa 453-783, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65.3 kDa and the accession number is AAA60275.1.
TMPH-00498	Prorelaxin Protein, Canine, Recombinant (His) RLN,Prorelaxin	Canine	E. coli
	Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. Prorelaxin Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.6 kDa and the accession number is Q9TRM8.
TMPH-01241	TOP1 Protein, Human, Recombinant (His & Myc) DNA topoisomerase 1,TOP1,DNA topoisomerase I	Human	Baculovirus Insect Cells
	Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then rotates a...

重组蛋白

ROR1 Protein, Canine, Recombinant (His)

Cat.No: TMPK-00572

Species: Canine

Expression System: HEK293 Cells

ROR1 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)

Cat.No: TMPK-00413

Species: Human,Cynomolgus,Rhesus

Expression System: HEK293 Cells

ROR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00579

Species: Human

Expression System: HEK293 Cells

ROR2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00577

Species: Human

Expression System: HEK293 Cells

ROR2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00566

Species: Cynomolgus

Expression System: HEK293 Cells

ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated

Cat.No: TMPK-00578

Species: Human

Expression System: HEK293 Cells

ROR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04649

Species: Human

Expression System: HEK293 Cells

ROR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-05394

Species: Human

Expression System: HEK293 Cells

RORC Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01792

Species: Human

Expression System: E. coli

RORA Protein, Human, Recombinant (His)

Cat.No: TMPH-01791

Species: Human

Expression System: E. coli

ROR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04068

Species: Human

Expression System: HEK293 Cells

ROR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-06508

Species: Mouse

Expression System: HEK293 Cells

ROR2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06850

Species: Mouse

Expression System: HEK293 Cells

ROR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06103

Species: Mouse

Expression System: HEK293 Cells

ROR1 Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-04986

Species: Human

Expression System: HEK293 Cells

ROR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06825

Species: Human

Expression System: HEK293 Cells

ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05603

Species: Human

Expression System: HEK293 Cells

ROR2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05639

Species: Human

Expression System: HEK293 Cells

ROR1 Protein, Human, Recombinant (aa 453-783, His & GST)

Cat.No: TMPY-04428

Species: Human

Expression System: Baculovirus Insect Cells

Prorelaxin Protein, Canine, Recombinant (His)

Cat.No: TMPH-00498

Species: Canine

Expression System: E. coli

TOP1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01241

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0160	Dextrorphan-d3 Tartrate Dextromethorphan EP Impurity B-d3 Tartrate
	Dextrorphan-d3 Tartrate 是 Dextrorphan Tartrate 的氘代化合物。Dextrorphan Tartrate 的 CAS 号为 77-07-6。Dextrorphan tartrate 是一种非竞争性 NMDA 谷氨酸受体拮抗剂。

同位素标记化合物

Dextrorphan-d3 Tartrate

Cat.No: TMIJ-0160

Synonym: Dextromethorphan EP Impurity B-d3 Tartrate

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