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Search Results for " rna "

Targets Recommended: DNA/RNA Synthesis DNA/RNA Synthesis

687

抑制剂 & 化合物

128

天然产物

8

化合物库

267

重组蛋白

16

同位素标记化合物

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Cat. No.	Product Name
L1200	表观遗传库		953 compounds
	953 种表观遗传学研究相关的生物活性小分子的特有集合，用于表观遗传学研究及其相关的检测和高通量、高内涵筛选；
L8100	细胞周期化合物库		677 compounds
	677 种细胞周期相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L6120	黄酮类天然产物库		514 compounds
	514 种黄酮类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
L5500	毒性化合物库		262 compounds
	262 个细胞毒性化合物的特有集合，可用于高通量、高内涵筛选。
L1380	转录因子库		695 compounds
	695 种转录因子靶向、结构新颖的化合物；
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；
L9420	外泌体相关化合物库		76 compounds
	76 种外泌体相关的化合物，可以用于高通量和高内涵筛选；
L3800	NF-κB 通路分子库		729 compounds
	729 个 NF-κB 信号通路相关的小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

表观遗传库

Cat.No: L1200

Compounds: 953

细胞周期化合物库

Cat.No: L8100

Compounds: 677

黄酮类天然产物库

Cat.No: L6120

Compounds: 514

毒性化合物库

Cat.No: L5500

Compounds: 262

转录因子库

Cat.No: L1380

Compounds: 695

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

外泌体相关化合物库

Cat.No: L9420

Compounds: 76

NF-κB 通路分子库

Cat.No: L3800

Compounds: 729

Cat. No.	Product Name	Target	Signaling Pathways
T79924	T4 RNA ligase	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	T4 RNA ligase为一RNA连接酶，催化单链DNA分子的连接作用。该酶在酶促低核糖核苷酸合成及RNA 3'端标记过程中应用。
T79923	T7 RNA polymerase	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	T7 RNA polymerase是一种由大肠杆菌表达的聚合酶，由T7噬菌体的RNA聚合酶基因编码。它在合成mRNA体外转录（IVT）过程中显示出高度专一性。T7 RNA polymerase能在Mg2+的作用下，针对含有T7启动子序列的单链或双链DNA模板，使用NTP作为底物进行RNA合成，产生的RNA与DNA模板的启动子下游区域互补。
T74884	RNA splicing modulator 1	Others	Others
	RNA splicing modulator 1 (compound 233) 是一种 RNA 剪接调节剂，AC50值 <100 nM。
T74885	RNA splicing modulator 2	Others	Others
	RNA splicing modulator 2 (compound 256) 是 RNA 拼接调节剂。
T74886	RNA splicing modulator 3	Others	Others
	RNA splicing modulator 3 (compound 236) 是一种 RNA 剪接调节剂，AC50值 <100 nM。
T74631	RNA polymerase II-IN-2	Others	Others
	RNA polymerase II-IN-2 (compound 20iii)是高效的RNA polymerase II (Pol II)抑制剂，其Ki值为74.1 nM。该化合物对癌细胞展现出细胞毒性，其对CHO和HEK293细胞的毒性分别为α-amanitin的2倍和5倍。
T81356	PTBP1-RNA-binding inhibitor P6 TFA PTBP1 α3-helix derived peptide P6 TFA
	PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA 为剪接因子PTBP1的特定钉合肽抑制剂，用于抑制PTBP1调控的RNA选择性剪接事件。该抑制剂通过与PTBP1的RNA识别基序相结合，从而发挥其作用。
T74630	RNA polymerase II-IN-1	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	RNA polymerase II-IN-1（compound 19iv）是一款鹅膏毒素类化合物，能够抑制RNA聚合酶II（Pol II），其半抑制浓度IC50为36.66 nM。该化合物相较于α-Amanitin，对癌细胞展现出更高的细胞毒性，而对正常细胞的毒性较低。
TD0005	SYBR GREEN II SUPER Green II RNA gel stain 10,000× concentrate in DMSO (Electrophoresis Grade),SUPER Green II （效果同SYBR Green II）RNA染料（10,000× DMSO溶液）（电泳级）
	1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity. 2) High sensitivity: at least 100pg ssDNA or RNA can be detected, which is 25 ~ 100 times higher than EB staining. 3) High SIGNal-to-noise ratio: the sample fluorescence signal is strong, while the background signal is low. 4) Simple operation: like EB, the dye does not degrade in the prefabricated gel and electrophoresis process;The dyeing process after electrophoresis takes only 30 minutes without decolor...
T1349	5-Fluorouridine	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	5-Fluorouridine 是一种 5-fluorouracil 的代谢物，具有抗癌作用。它对 L1210 细胞的生长具有细胞毒性作用，其作用的 IC50值为 2 nM。它能抑制人结肠癌细胞 rRNA 的合成。
T36971	5-Ethynyluridine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	5-Ethynyluridine 可用于标记新合成的 RNA。这种方法称为使用点击化学 (RICK) 捕获新转录的 RNA 相互作用组，系统地捕获与多种 RNA 结合的蛋白质，包括新生 RNA 和传统上被忽视的非多腺苷酸化 RNA。
T83729	Tat-CIRP TFA Tat-Cold-inducible RNA Binding Protein
	Tat-CIRP是一种肽类抑制剂，用于抑制髓样分化2蛋白(MD-2，亦称淋巴细胞抗原96 [LY96])与寒冷诱导的RNA结合蛋白(CIRP)之间的蛋白-蛋白相互作用。它通过与MD-2结合，干扰MD-2与CIRP之间的相互作用，这一作用在共免疫沉淀实验中得到证实。在体内实验中，Tat-CIRP (10及20 mg/kg) 能够减少由中脑动脉闭塞(MCAO)引发的小鼠脑梗死体积。同样，在通过血栓引发脑梗死的恒河猴模型中，Tat-CIRP同样能减少脑梗死体积，并缩短患中风一侧手臂抓取并放下食物的时间。
T8354	Triazavirin	Nucleoside Antimetabolite/Analog; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Triazavirin 是一种核酸的核苷类似物和抗病毒剂，通过抑制病毒 RNA 和 DNA 的合成以及基因组片段的复制而起作用。在流感传播阶段，它可作为保护剂。
T1767	BMH-21 BMH21	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	BMH-21 是一种小分子 DNA 嵌入剂，可结合核糖体 DNA 并抑制 RNA 聚合酶 I (Pol I) 转录，具有抗癌活性。
T14522	Beaucage reagent	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Beaucage reagent 可用于DNA切割。
T13166	TK216	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	TK216 是一种口服有效的 E26 转录因子抑制剂，具有抗癌活性。它直接结合 EWS-FLI1 并抑制 EWS-FLI1 蛋白质相互作用，也可阻止 EWS-FLI1 与 RNA 解旋酶 A 的结合。
T12019	Methylproamine	Others	Others
	Methylproamine是一种与DNA结合的辐射保护剂，可以修复辐射诱导的短暂活性氧。
T15611	JH-RE-06	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	JH-RE-06是一种REV1-REV7互作抑制剂，IC50为0.78 μM，Kd 为0.42 μM。它靶向与 POLζ 的 REV7 亚基相互作用的 REV1，可改善化疗效果。它通过阻止诱变 POLζ 的募集来破坏诱变性跨损伤合成。
T6801	CeMMEC13	Carboxypeptidase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Proteases/Proteasome
	CeMMEC13 是一种异喹啉酮，可选择性抑制 TAF1 的第二个溴结构域，IC50为 2.1 μM。
T26674	AT-130 AT 130	HBV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	AT-130 是一种苯基丙烯酰胺衍生物，是乙型肝炎病毒复制的非核苷抑制剂。它抑制病毒 DNA 的合成，EC50为 0.13 μM。
T1154	Rifaximin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Rifaximin 是一种胃肠道选择性抗生素，与细菌 DNA 依赖性 RNA 聚合酶的 β 亚基结合，抑制细菌 RNA 合成。与革兰氏阴性菌（MIC：8-50 毫克/毫升）相比，它对革兰氏阳性菌株（MIC：0.03-5 毫克/毫升）的敏感性更高。
TP1115	L-Asparaginase L-ASNase	Others	Others
	L-Asparaginase (L-ASNase) 是催化 L-天冬酰胺转化的水解酶，从血浆中去除 L-天冬酰胺，导致 RNA 和 DNA 合成抑制，随后引起细胞凋亡。它用于急性淋巴细胞白血病的研究。
T8955	PCNA-I1	Others	Others
	PCNA-I1 是PCNA(增殖细胞核抗原)抑制剂。它能够直接与 PCNA 三聚体结合(Kd:0.41 μM)，在体内外均表现出抗肿瘤活性。
T3489	Dasabuvir ABT-333,达塞布韦	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Dasabuvir (ABT-333) 是丙型肝炎病毒非结构蛋白 5B 的非核苷抑制剂，是一种 RNA 依赖性 RNA 聚合酶，具有抗 HCV 的潜在活性。
T8886	NITD-2	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	NITD-2 是一种登革病毒 (DENV) 聚合酶抑制剂，可抑制 DENV RdRp 介导的 RNA 延伸。
T4686	Simeprevir TMC435,西咪匹韦,TMC-435350,Olysio	HCV Protease; SARS-CoV	Microbiology/Virology; Proteases/Proteasome
	Simeprevir (TMC435) 是一种有效的 HCV NS3/4A 蛋白酶抑制剂，抑制 HCV 复制，EC50 为 7.8 nM。它也是 SARS-CoV-2 3CLpro 抑制剂。
T2037	TH588	DNA/RNA Synthesis; MTH1	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	TH588 是 nudix 水解酶家族抑制剂，可有效和选择性地参与和抑制细胞中的 MTH1，IC50值 5 nM。
T2100	CX-5461	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	CX5461 是一种口服有效的rRNA 合成抑制剂，可抑制 Pol I 驱动的 rRNA 转录。
T40168	DHODH-IN-16	Dehydrogenase	Metabolism
	DHODH-IN-16 是一种有效的二氢乳清酸脱氢酶抑制剂（DHODH，IC50 = 0.396 nM）。
T14501	BAY-2402234	Dehydrogenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	BAY-2402234 是一种选择性二氢乳清酸脱氢酶的抑制剂，可研究骨髓恶性肿瘤。
T36757	DMT-dU-CE Phosphoramidite	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	DMT-dU-CE Phosphoramidite 是一个核苷分子，通常用于合成 DNA 和 DNA 测序试验。
T16961	Supinoxin RX-5902	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Supinoxin (RX-5902) 是磷酸化 p68 RNA 解旋酶的强效口服活性抑制剂，是一种抗肿瘤试剂。它与 Y593 磷酸化的 p68 相互作用并减弱 β-catenin 的核穿梭性。它诱导细胞凋亡并抑制 TNBC 癌细胞系的生长，IC50的范围为 10 nM 至 20 nM。
T2410	Nedaplatin 奈达铂,NSC 375101D	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Nedaplatin (NSC-375101D) 是顺铂的衍生物，是肿瘤集落形成单位的 DNA 损伤剂，IC50为94 μM。
T36687	Ac-rC Phosphoramidite	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Ac-rC Phosphoramidite 可以修饰二硫化磷酸寡核苷酸。
T1233	Oxolinic acid Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox	Dopamine Receptor; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Microbiology/Virology; Neuroscience
	Oxolinic acid (Nidantin) 是一种抗生素，对革兰氏阴性菌和革兰氏阳性菌均有效，可研究急性和慢性尿路感染。它是一种 DNA/RNA 合成抑制剂，也是一种多巴胺摄取抑制剂，能刺激小鼠的活跃过度。
T8873	Bractoppin	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Bractoppin 是一种BRCA1 (t)BRCT domain 识别磷酸肽的选择性抑制剂，IC50为 74 nM。它优先抑制 BRCA1 -tBRCT 依赖的 DNA 损伤。它减少 BRCA1 对 DNA 断裂片段的招募，进而抑制损伤诱导的 G2 期阻滞和重组酶 RAD51 的组装。
T38889	Thailanstatin A	Others; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; Others
	Thailanstatin A 是真核 RNA 剪接抑制剂，IC50为650 nM，通过非共价结合到剪接体的 U2 snRNA 亚复合物的 SF3b 亚单位发挥作用。Thailanstatin A 对多种癌细胞系的抑制显示 nM 级别的 IC50。它与 Trastuzumab 上的赖氨酸结合，可产生“无连接子” ADC。
T15235	Enocitabine	Nucleoside Antimetabolite/Analog; HCV Protease; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Enocitabine 是一种核苷类似物，抑制 DNA 复制剂。Enocitabine 抑制人巨细胞病毒的复制，显示出抗白血病和抗病毒活性。
T7747	Datelliptium chloride hydrochloride	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Datelliptium chloride hydrochloride 是一种衍生自玫瑰树碱的 DNA 嵌入剂，具有抗肿瘤活性。
T35648	4-Thiouridine	Others	Others
	4-Thiouridine (4-TU) 是一种光活化核糖核苷类似物，广泛用于RNA 分析。
T38237	2′-O-Methylcytidine	Nucleoside Antimetabolite/Analog; HCV Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	2'-O-Methylcytidine 是 2'-代核苷，可抑制 HCV 复制。它在体外抑制 NS5B 催化的 RNA 合成，其抑制方式是与底物核苷三磷酸竞争。
T12438	PfDHODH-IN-1	Dehydrogenase; Parasite	Metabolism; Microbiology/Virology
	PfDHODH-IN-1 是 Leflunomide 活性代谢物的类似物，具有抗疟疾活性。它是恶性疟原虫二氢乳清酸脱氢酶抑制剂。
T16703	Quarfloxin CX-3543	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Quarfloxin (CX-3543) 是一种氟喹诺酮衍生物，具有抗肿瘤活性，可靶向抑制RNA pol I 的活性，在神经母细胞瘤细胞中的 IC50 值在纳摩尔范围内。它破坏核糖体 DNA 模板中核仁蛋白和 G-四链体 DNA 结构之间的相互作用。
T9111	8-Azaadenosine	Adenosine deaminase	Metabolism
	8-Azaadenosine 是 ADAR1抑制剂和是 A-to-I 编辑抑制剂。它可阻断 RNA 编辑并抑制甲状腺癌细胞的增殖、3D 生长、侵袭和迁移。
T4345	CeMMEC1 CeMMEC1 HCl	Epigenetic Reader Domain; Carboxypeptidase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
	CeMMEC1 是一种 BRD4 抑制剂，对 TAF1 有很好的亲和力，IC50为0.9 μM。
T13659	DMTr-LNA-5MeU-3-CED-phosphoramidite	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	DMTr-LNA-5MeU-3-CED-phosphoramidite 是核苷的衍生物。
T14495	Baloxavir Baloxavir acid,S-033447	Influenza Virus	Microbiology/Virology
	Baloxavir (S-033447) 是衍生自前药 Baloxavir marboxil，是流感病毒聚合酶 PA 亚基的一流帽依赖性核酸内切酶抑制剂。它抑制病毒 RNA 的转录和复制，具有强大的抗病毒活性。
T40661	ML-60218	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	ML-60218 是广谱 RNA pol III 抑制剂，对酿酒酵母和人类的 IC50 分别为 32 和 27 μM。 ML-60218 会破坏已组装的病毒质并阻碍新病毒质的形成。
T11020	DHODH-IN-11	Dehydrogenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	DHODH-IN-11 是一种来氟米特衍生物和弱二氢乳清酸脱氢酶 (DHODH) 抑制剂，pKa 为 5.03
T9103	BVDV-IN-1	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	BVDV-IN-1 是一种牛病毒性腹泻病毒 (BVDV) 的非核苷抑制剂 (NNI)，EC50 为 1.8 μM。它直接与 BVDV RdRp 的疏水口袋结合，对耐 NNI 氨基硫脲 (TSC) 的 BVDV 具有抗病毒活性。

化合物

T4 RNA ligase

Cat.No: T79924

Target: DNA/RNA Synthesis

T7 RNA polymerase

Cat.No: T79923

Target: DNA/RNA Synthesis

RNA splicing modulator 1

Cat.No: T74884

Target: Others

RNA splicing modulator 2

Cat.No: T74885

Target: Others

RNA splicing modulator 3

Cat.No: T74886

Target: Others

RNA polymerase II-IN-2

Cat.No: T74631

Target: Others

PTBP1-RNA-binding inhibitor P6 TFA

Cat.No: T81356

Synonym: PTBP1 α3-helix derived peptide P6 TFA

RNA polymerase II-IN-1

Cat.No: T74630

Target: DNA/RNA Synthesis

Cat.No: TD0005

Synonym: SUPER Green II RNA gel stain *10,000× concentrate in DMSO* (Electrophoresis Grade),SUPER Green II （效果同SYBR Green II）RNA染料（10,000× DMSO溶液）（电泳级）

5-Fluorouridine

Cat.No: T1349

Target: Others, DNA/RNA Synthesis

5-Ethynyluridine

Cat.No: T36971

Target: Nucleoside Antimetabolite/Analog

Cat.No: T83729

Synonym: Tat-Cold-inducible RNA Binding Protein

Cat.No: T8354

Target: Nucleoside Antimetabolite/Analog, Influenza Virus, DNA/RNA Synthesis

Cat.No: T1767

Synonym: BMH21

Target: DNA/RNA Synthesis

Beaucage reagent

Cat.No: T14522

Target: DNA/RNA Synthesis

Cat.No: T13166

Target: Others, DNA/RNA Synthesis

Cat.No: T12019

Target: Others

Cat.No: T15611

Target: DNA/RNA Synthesis

Cat.No: T6801

Target: Carboxypeptidase, DNA/RNA Synthesis

Cat.No: T26674

Synonym: AT 130

Target: HBV, DNA/RNA Synthesis

Cat.No: T1154

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: TP1115

Synonym: L-ASNase

Target: Others

Cat.No: T8955

Target: Others

Cat.No: T3489

Synonym: ABT-333,达塞布韦

Target: HCV Protease

Cat.No: T8886

Target: DNA/RNA Synthesis

Cat.No: T4686

Synonym: TMC435,西咪匹韦,TMC-435350,Olysio

Target: HCV Protease, SARS-CoV

Cat.No: T2037

Target: DNA/RNA Synthesis, MTH1

Cat.No: T2100

Target: DNA/RNA Synthesis

Cat.No: T40168

Target: Dehydrogenase

Cat.No: T14501

Target: Dehydrogenase, DNA/RNA Synthesis

DMT-dU-CE Phosphoramidite

Cat.No: T36757

Target: DNA/RNA Synthesis

Cat.No: T16961

Synonym: RX-5902

Target: Apoptosis, DNA/RNA Synthesis

Cat.No: T2410

Synonym: 奈达铂,NSC 375101D

Target: DNA/RNA Synthesis

Ac-rC Phosphoramidite

Cat.No: T36687

Target: Nucleoside Antimetabolite/Analog

Cat.No: T1233

Synonym: Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox

Target: Dopamine Receptor, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T8873

Target: Others, DNA/RNA Synthesis

Thailanstatin A

Cat.No: T38889

Target: Others, ADC Cytotoxin

Cat.No: T15235

Target: Nucleoside Antimetabolite/Analog, HCV Protease, DNA/RNA Synthesis

Datelliptium chloride hydrochloride

Cat.No: T7747

Target: DNA/RNA Synthesis

Cat.No: T35648

Target: Others

2′-O-Methylcytidine

Cat.No: T38237

Target: Nucleoside Antimetabolite/Analog, HCV Protease

Cat.No: T12438

Target: Dehydrogenase, Parasite

Cat.No: T16703

Synonym: CX-3543

Target: DNA/RNA Synthesis

Cat.No: T9111

Target: Adenosine deaminase

Cat.No: T4345

Synonym: CeMMEC1 HCl

Target: Epigenetic Reader Domain, Carboxypeptidase, DNA/RNA Synthesis

DMTr-LNA-5MeU-3-CED-phosphoramidite

Cat.No: T13659

Target: Nucleoside Antimetabolite/Analog

Cat.No: T14495

Synonym: Baloxavir acid,S-033447

Target: Influenza Virus

Cat.No: T40661

Target: DNA/RNA Synthesis

Cat.No: T11020

Target: Dehydrogenase, DNA/RNA Synthesis

Cat.No: T9103

Target: DNA/RNA Synthesis

Cat. No.	Product Name	Target	Signaling Pathways
T13499	3-Methyluridine	Endogenous Metabolite	Metabolism
	3-Methyluridine 是一种修饰的细胞 RNA 的核苷(RNA nucleoside)。它通常以 RNA 修饰的形式出现，能够在古菌的 23S rRNA、真细菌的 16S 和 23S rRNA 以及真核核糖体 18S、25S 和 28SRNA 的中检测到。
T13969	Xanthopterin (hydrate)	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Xanthopterin hydrate 是东方大黄蜂翅膀中黄色颗粒的主要成分，是一种非共轭的蝶啶天然产物，在 386/456 nm 处产生特征性的激发光。它可抑制 RNA 合成，引起大鼠肾脏生长和肥大。
T40179	Sodium Camptothecin	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Sodium Camptothecin 是一种植物生物碱，具有抗肿瘤活性。它是可逆 RNA 合成抑制剂，可以抑制腺病毒的复制。它能抑制 DNA 合成，并引起细胞内预形成的病毒 DNA 断裂。
T24729	Roseoflavin	Antibacterial	Microbiology/Virology
	Roseoflavin 是天然色素，起初分离自Streptomyces davawensis。Roseoflavin 是核黄素和黄素单核苷酸的抗代谢类似物，显示出抗菌活性。
T5270	5-Methylcytosine	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	5-Methylcytosine 是一种存在于真核 DNA 中的甲基化核苷酸碱基。它是由 DNA 甲基转移酶作用形成的表观遗传修饰。
T2S1635	3-Isomangostin	MTH1	DNA Damage/DNA Repair
	3-Isomangostin 可从莽吉柿壳中提取的一种天然产物，是一种乙酰胆碱酯酶选择性抑制剂，也是一种有效的人醛糖还原酶抑制剂，IC50 为 3.48 uM。它抑制 MutT 同源物 1 (MTH1)，IC50 为 52 nM。它具有清除自由基、抗疟原虫和抗癌的活性。
TN1134	Euscaphic acid	Apoptosis; LDL; PI3K; DNA/RNA Synthesis; NO Synthase; Prostaglandin Receptor	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; PI3K/Akt/mTOR signaling
	Euscaphic acid 是来源于枣的一种三萜，是DNA 聚合酶抑制剂，可诱导细胞凋亡。它抑制小牛 DNA 聚合酶 α 和大鼠 DNA 聚合酶 β 的IC50值分别为 61 和 108 μM。
T21498	Phleomycin	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Phleomycin 是在链霉菌中发现的，引起 DNA 切割的抗癌糖肽抗生素之一。它类似于博来霉素，它结合并插入 DNA 以破坏双螺旋的完整性。
T1465	Mupirocin Pseudomonic acid,莫匹罗星,BRL-4910A	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Mupirocin (BRL-4910A) 是从Pseudomonas fluorescens 中分离得到的一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA，并抑制细菌蛋白和RNA 的合成起抗菌作用。
T5901	3-Hydroxy-2-methylpyridine	Others	Others
	3-Hydroxy-2-methylpyridine 是分离自可可碱提取物，可用于合成嘧啶。
T1068	Dithranol 1,8,9-trihydroxyanthracene,cignoline,蒽林,Anthralin	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	Dithranol (cignoline) 是蒽醌衍生物，可破坏线粒体功能和结构，用于治疗皮肤病。
T37101	1-Hydroxyanthraquinone	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	1-Hydroxyanthraquinone 是口服有效的天然产物，来源于植物 Tabebuia avellanedae，显示出致癌活性。
TQ0184	Chebulinic acid	ATPase; Proton pump; DNA/RNA Synthesis; Antibacterial; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Stem Cells
	Chebulinic acid 是从诃子果中提取的一种天然产物，结核分枝杆菌 DNA 促旋酶的有效抑制剂。它也能抑制 SMAD-3 phosphorylation 和 H+ K+-ATPase 的活性。
T8148	Mupirocin calcium hydrate 莫匹罗星钙,Mupirocin calcium	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Mupirocin calcium hydrate 是从Pseudomonas fluorescens 中分离得到的，一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA，并抑制细菌蛋白和RNA 的合成起到抗菌作用。
T35455	N-Nitrosodiethylamine Diethylnitrosamine,NDEA	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	N-Nitrosodiethylamine (NDEA) 是致癌物质二烷基硝胺。它主要存在于水、烟草烟雾、腌制食品、油炸食品以及许多酒精饮料中。它与 DNA 修复/复制相关的核酶的变化相关。
T7520	Deoxycytidine triphosphate	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Deoxycytidine triphosphate 是一种核苷三磷酸，是合成 DNA 的原料，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
T6S0232	Eriodictyol 圣草酚,Huazhongilexone	Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物，具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 18 nM。它可诱导Nrf2信号通路。
T6S0139	Neobavaisoflavone	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎，抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶，也可抑制血小板聚集。
T16674	Pseudouridine	Endogenous Metabolite	Metabolism
	Pseudouridine 是非编码 RNA 中丰富的修饰核苷，通过稳定 RNA 结构增强核糖体 RNA 和的转移 RNA 功能。
T17143	Toyocamycin 丰加霉素,Vengicide	Apoptosis; Others; IRE1; Antibiotic; Antifungal	Apoptosis; Cell Cycle/Checkpoint; Microbiology/Virology; Others
	Toyocamycin (Vengicide) 是放线菌类产生的腺苷类似物，为 X 盒结合蛋白 1 (XBP1) 抑制剂，抑制 IRE1α 诱导的 ATP 依赖性 XBP1 mRNA 的断裂，IC50值为 80 nM。它还诱导凋亡。
T6194	Fidaxomicin 非达米星,Tiacumicin B,OPT-80,Clostomicin B1,PAR-101	Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Fidaxomicin (Tiacumicin B) 是一种大环RNA 聚合酶抑制剂，具有窄谱活性。它选择性地根除致病性艰难梭菌，对构成正常健康肠道菌群的多种细菌影响很小。
T4593	ISOPIMPINELLIN 5,8-Dimethoxypsoralen,异茴芹内酯,4,9-Dimethoxypsoralen	Antiviral; DNA/RNA Synthesis; Parasite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology
	Isopimpinellin (4,9-Dimethoxypsoralen) 是从 Pimpinella saxifrage 根部分离得到的一种天然产物，具有抗病毒和抗利什曼病活性。
T9715	Aplidine	SARS-CoV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Aplidine 是有效的eEF1A2(KD=80 nM) 靶向的抗癌药物。Aplidine 具有抗病毒活性，抑制SARS-CoV-2的 IC90为 0.88 nM。Aplidine 在多发性骨髓瘤，晚期癌症及 COVID-19 领域有研究的价值。
T2998	Dihydromyricetin Ampelopsin,Ampeloptin,二氢杨梅素	Influenza Virus; GABA Receptor; DNA/RNA Synthesis; mTOR; Autophagy	Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
	Dihydromyricetin (Ampelopsin) 是一种来自 Ampelopsis Grossedentata 的天然抗氧化剂类黄酮，是二氢嘧啶酶抑制剂，IC50 为 48 μM。它通过抑制mTOR 信号从而激活自噬。它还是流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 22 μM。
TN2132	Quinizarin 1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌	Others; DNA/RNA Synthesis; Antifungal	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Quinizarin (1,4-Dihydroxyanthraquinone) 是一种杀菌剂和杀虫剂，可抑制肿瘤细胞生长。
T13791	N2-methylguanine 6-羟基-2-氨甲基嘌呤	DNA/RNA Synthesis; Endogenous Metabolite; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	N2-methylguanine (N2-methylguanine) 是一种在人体体液中发现的内源性甲基化核苷，是一种修饰的核苷。
T0064	Adenine Vitamin B4,腺嘌呤,6-Aminopurine	DNA/RNA Synthesis; Endogenous Metabolite; AChR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Neuroscience
	Adenine (6-Aminopurine) 是一种嘌呤衍生物，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
TWP2911	Thymidine beta-胸苷,5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Thymidine (DThyd) 是一种细胞同步剂，是脱氧核糖核酸的特殊前体。它可在 DNA 复制前在 G1/S 边界阻滞细胞，是DNA 合成抑制因子。
TN1097	β-Boswellic acid Beta-boswellic acid,β-乳香酸	Lipoxygenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	β-Boswellic acid (Beta-boswellic acid) 是从乳香的树胶脂中分离出来的一种天然产物。它是 5-脂氧合酶(5-LO) 产物形成的非还原型抑制剂，其直接与 5-LO 相互作用或阻断其易位。具有抗癌、抗肿瘤和抗高血脂活性。
T40426	Cytidine 5'-diphosphate trisodium salt CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐	Others	Others
	Cytidine 5'-diphosphate trisodium salt (CDP) 可通过尿苷单磷酸激酶 (UMPK) 催化将磷酸基从 ATP 转移到胞苷一磷酸 (CMP) 生成用于合成 DNA 和 RNA 的胞苷三磷酸。
T7004	Tubercidin 结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine	Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Tubercidin (Sparsomycin A) 是从Streptomyces tubercidicus 得到的抗生素，抑制粪链球菌生长的IC50值为 0.02 μM。它是腺苷磷酸化酶的弱抑制剂，并干扰腺苷和 AMP 的磷酸化。它有抗病毒作用。
T6116	Bleomycin Sulfate Blenoxane,硫酸博来霉素,硫酸博莱霉素,NSC125066	DNA/RNA Synthesis; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Bleomycin Sulfate (Blenoxane) 是一种糖肽抗生素，一种 DNA 合成抑制剂。Bleomycin Sulfate 可以引起 DNA 链断裂而不引起 RNA 链断裂。Bleomycin Sulfate 具有抗肿瘤活性。
T3343	5-methoxyflavone 5-methoxy-2-phenylchromen-4-one,5-甲氧基黄酮	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) 是一种类黄酮，是DNA 聚合酶 β 的抑制剂和 β-淀粉样蛋白毒性的神经保护剂。它通过调控嗜离子 GABAA 受体，起到镇静中枢神经系统的作用。
T6758	Anisomycin 茴香霉素,Flagecidin,NSC 76712,Wuningmeisu C	Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic; JNK	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; MAPK; Microbiology/Virology
	Anisomycin (Flagecidin) 属于细菌抗生素，是一种蛋白合成抑制剂和一种 JNK 激活剂。Anisomycin 通过抑制肽基转移酶或 80S 核糖体系统来干扰蛋白质和 DNA 的合成。
T7174	Urolithin A 尿石素A,3,8-二羟基-6H-二苯并[B,D]吡喃-6-酮	Apoptosis; Reactive Oxygen Species; DNA/RNA Synthesis; Endogenous Metabolite; Autophagy; Drug Metabolite	Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; NF-κB
	Urolithin A 是一种鞣花酸的肠道微生物代谢产物，可诱导自噬和凋亡，抑制细胞周期进程，抑制DNA 合成，具有抗炎、抗增殖和抗氧化的特性。
TN2111	Prunin Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷	Phosphatase; Anti-infection; Virus Protease	Metabolism; Microbiology/Virology
	Prunin (Naringenin 7-0-glucoside) 是一种人肠道病毒 A71 抑制剂。它抑制蛋白酪氨酸磷酸酶 1B，IC50值为 5.5 μM。
T1335	Mycophenolic acid 霉酚酸,Mycophenolate,RS-61443	Apoptosis; Dehydrogenase; Endogenous Metabolite; Antibacterial; Antibiotic; UGT; Antifungal	Apoptosis; Metabolism; Microbiology/Virology
	Mycophenolic acid (Mycophenolate) 是一种有效的非竞争性肌苷单磷酸脱氢酶 (IMPDH) 抑制剂，EC50为 0.24 µM。它对多种 RNA 病毒具有抗病毒作用。它也是一种免疫抑制剂，具有抗血管生成和抗肿瘤作用。
T0746	Orotic acid 乳清酸,Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog; Dehydrogenase; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Orotic acid (Vitamin B13) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T38427	dUTP trisodium 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	dUTP trisodium (Deoxyuridine triphosphate) 是在 5'-位具有三磷酸基团的脱氧尿苷磷酸盐，可用于 PCR。
T6567	Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin (Fluoroquinolone) 是合成的氟喹诺酮类抗生素，有抑制细菌DNA 旋转酶的超螺旋活性的作用，能阻止DNA 复制。
T0062	Folic acid Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,叶酸,Folacin	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Folic acid (Vitamin B9) 是维生素B9，是合成DNA/RNA，新细胞产生和维持的必要成分。
T6225	Adenine hydrochloride Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenine hydrochloride (6-Aminopurine hydrochloride) 是一种嘌呤，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T1591L	Cytidine Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Cytidine (Cytosine-1-β-D-ribofuranoside) 是一种嘧啶核苷，由通过 β-N1-糖苷键与核糖结合的胞嘧啶组成。它是尿苷的前体，用于 RNA 合成。
T8186	Xanthosine 5'-monophosphate sodium salt XMP,黄苷-5′-单磷酸钠,L-XMP Sodium	Others	Others
	Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) 是嘌呤代谢的一种中间体。它可用于研究遗传密码，核酸结构以及 DNA，RNA 和蛋白质合成。
T6369	Adenine hemisulfate 硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐	DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Adenine hemisulfate (Diadenine sulphate) 是一种嘌呤，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
T1507	Streptozocin STZ,Streptozotocin,链脲佐菌素,NSC-85998,链脲菌素,U 9889	DNA Alkylator/Crosslinker; DNA Alkylation; DNA/RNA Synthesis; Antibacterial; Antibiotic; Autophagy	Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Streptozocin (NSC-85998) 是一种抗生素，可诱导 DNA 甲基化。Streptozocin 对产生胰岛素的胰岛 B 细胞具有毒性，常用于构建 1 型糖尿病的动物模型。该产品在溶液中不稳定，建议现配现用。
T0974	Novobiocin Sodium Albamycinsodium,新生霉素钠,Cathomycin,Albamycin	Potassium Channel; DNA gyrase; Topoisomerase; Antibacterial; Antibiotic; ABC; Autophagy	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology
	Novobiocin Sodium (Albamycinsodium) 是源自 Streptomyces niveus 的抗生素。它的化学结构类似于香豆素。Novobiocin 与 DNA 促旋酶结合并阻断三磷酸腺苷活性。
T20945	2,4-D Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2,4-Dichlorophenoxyacetic acid (Hedonal) 是一种合成生长素，用作植物生长调节剂，也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分，用于破坏肌动蛋白细胞骨架，以控制根系伸长和细胞生成。
T3271	Orotic acid zinc 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate	Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Orotic acid zinc (Zinc Orotate) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T3376	Cynaroside 朝蓟糖甙,Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,木犀草苷,Luteolin 7-glucoside	Others; Influenza Virus; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Cynaroside (Luteolin 7-O-Glucoside) 是一个抗氧化类黄酮。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 32 nM。
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天然产物

3-Methyluridine

Cat.No: T13499

Target: Endogenous Metabolite

Xanthopterin (hydrate)

Cat.No: T13969

Target: Others, DNA/RNA Synthesis

Sodium Camptothecin

Cat.No: T40179

Target: DNA/RNA Synthesis

Cat.No: T24729

Target: Antibacterial

5-Methylcytosine

Cat.No: T5270

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T2S1635

Target: MTH1

Cat.No: TN1134

Target: Apoptosis, LDL, PI3K, DNA/RNA Synthesis, NO Synthase, Prostaglandin Receptor

Cat.No: T21498

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T1465

Synonym: Pseudomonic acid,莫匹罗星,BRL-4910A

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

3-Hydroxy-2-methylpyridine

Cat.No: T5901

Target: Others

Cat.No: T1068

Synonym: 1,8,9-trihydroxyanthracene,cignoline,蒽林,Anthralin

Target: Others, DNA/RNA Synthesis

1-Hydroxyanthraquinone

Cat.No: T37101

Target: DNA/RNA Synthesis

Chebulinic acid

Cat.No: TQ0184

Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad

Mupirocin calcium hydrate

Cat.No: T8148

Synonym: 莫匹罗星钙,Mupirocin calcium

Target: Others, Antibacterial, Antibiotic

N-Nitrosodiethylamine

Cat.No: T35455

Synonym: Diethylnitrosamine,NDEA

Target: DNA/RNA Synthesis

Deoxycytidine triphosphate

Cat.No: T7520

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T6S0232

Synonym: 圣草酚,Huazhongilexone

Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite

Neobavaisoflavone

Cat.No: T6S0139

Target: Apoptosis, DNA/RNA Synthesis

Cat.No: T16674

Target: Endogenous Metabolite

Cat.No: T17143

Synonym: 丰加霉素,Vengicide

Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal

Cat.No: T6194

Synonym: 非达米星,Tiacumicin B,OPT-80,Clostomicin B1,PAR-101

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T4593

Synonym: 5,8-Dimethoxypsoralen,异茴芹内酯,4,9-Dimethoxypsoralen

Target: Antiviral, DNA/RNA Synthesis, Parasite

Cat.No: T9715

Target: SARS-CoV, DNA/RNA Synthesis

Dihydromyricetin

Cat.No: T2998

Synonym: Ampelopsin,Ampeloptin,二氢杨梅素

Target: Influenza Virus, GABA Receptor, DNA/RNA Synthesis, mTOR, Autophagy

Cat.No: TN2132

Synonym: 1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌

Target: Others, DNA/RNA Synthesis, Antifungal

N2-methylguanine

Cat.No: T13791

Synonym: 6-羟基-2-氨甲基嘌呤

Target: DNA/RNA Synthesis, Endogenous Metabolite, Antibacterial

Cat.No: T0064

Synonym: Vitamin B4,腺嘌呤,6-Aminopurine

Target: DNA/RNA Synthesis, Endogenous Metabolite, AChR

Cat.No: TWP2911

Synonym: beta-胸苷,5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

β-Boswellic acid

Cat.No: TN1097

Synonym: Beta-boswellic acid,β-乳香酸

Target: Lipoxygenase, DNA/RNA Synthesis

Cytidine 5'-diphosphate trisodium salt

Cat.No: T40426

Synonym: CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐

Target: Others

Cat.No: T7004

Synonym: 结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine

Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic

Bleomycin Sulfate

Cat.No: T6116

Synonym: Blenoxane,硫酸博来霉素,硫酸博莱霉素,NSC125066

Target: DNA/RNA Synthesis, Antibiotic

5-methoxyflavone

Cat.No: T3343

Synonym: 5-methoxy-2-phenylchromen-4-one,5-甲氧基黄酮

Target: DNA/RNA Synthesis

Cat.No: T6758

Synonym: 茴香霉素,Flagecidin,NSC 76712,Wuningmeisu C

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic, JNK

Cat.No: T7174

Synonym: 尿石素A,3,8-二羟基-6H-二苯并[B,D]吡喃-6-酮

Target: Apoptosis, Reactive Oxygen Species, DNA/RNA Synthesis, Endogenous Metabolite, Autophagy, Drug Metabolite

Cat.No: TN2111

Synonym: Naringenin 7-0-glucoside,柚皮素-7-O-葡萄糖苷

Target: Phosphatase, Anti-infection, Virus Protease

Mycophenolic acid

Cat.No: T1335

Synonym: 霉酚酸,Mycophenolate,RS-61443

Target: Apoptosis, Dehydrogenase, Endogenous Metabolite, Antibacterial, Antibiotic, UGT, Antifungal

Cat.No: T0746

Synonym: 乳清酸,Vitamin B13,6-Carboxyuracil

Target: Nucleoside Antimetabolite/Analog, Dehydrogenase, Endogenous Metabolite

Cat.No: T38427

Synonym: 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate

Target: DNA/RNA Synthesis

Cat.No: T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T0062

Synonym: Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,叶酸,Folacin

Target: DNA/RNA Synthesis, Endogenous Metabolite

Adenine hydrochloride

Cat.No: T6225

Synonym: Adenine HCl,腺嘌呤盐酸盐,6-Aminopurine hydrochloride

Target: DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T1591L

Synonym: Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Xanthosine 5'-monophosphate sodium salt

Cat.No: T8186

Synonym: XMP,黄苷-5′-单磷酸钠,L-XMP Sodium

Target: Others

Adenine hemisulfate

Cat.No: T6369

Synonym: 硫酸腺嘌呤,Diadenine sulphate,Adenine sulfate,Adeninsulfat,1H-嘌呤-6-胺硫酸盐

Target: DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T1507

Synonym: STZ,Streptozotocin,链脲佐菌素,NSC-85998,链脲菌素,U 9889

Target: DNA Alkylator/Crosslinker, DNA Alkylation, DNA/RNA Synthesis, Antibacterial, Antibiotic, Autophagy

Novobiocin Sodium

Cat.No: T0974

Synonym: Albamycinsodium,新生霉素钠,Cathomycin,Albamycin

Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy

Cat.No: T20945

Synonym: Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸

Target: DNA/RNA Synthesis

Orotic acid zinc

Cat.No: T3271

Synonym: 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

Cat.No: T3376

Synonym: 朝蓟糖甙,Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,木犀草苷,Luteolin 7-glucoside

Target: Others, Influenza Virus, DNA/RNA Synthesis

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-06071	SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 108.3 kDa and the accession number is YP_009725307.1.
TMPH-00533	T7 RNA polymerase Protein, Enterobacteria phage T7, Recombinant (His & Myc) T7 RNA polymerase,DNA-directed RNA polymer...	Escherichia phage T7	E. coli
	Highly processive DNA-dependent RNA polymerase that catalyzes the transcription of class II and class III viral genes. Recognizes a specific promoter sequence and enters first into an 'abortive phase' where very short transcripts are synthesized and released before proceeding to the processive transcription of long RNA chains. Unwinds the double-stranded DNA to expose the coding strand for templating. Participates in the initiation of viral DNA replication presumably by making primers accessible...
TMPH-03184	P2 Protein, Pseudomonas phage phi6, Recombinant (His & Myc) P2,Protein P2,RNA-directed RNA polymerase	Pseudomonas phage phi6	E. coli
	Rna-dependent RNA polymerase part of the packaging complex that packages the viral RNA segments, replicate them into a double-stranded form and transcribe them. P2 Protein, Pseudomonas phage phi6, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.2 kDa and the accession number is P11124.
TMPH-03734	Zaire ebolavirus (strain Mayinga-76) L Protein (His) Transcriptase,L,RNA-directed RNA polymeras...	ZEBOV	E. coli
	Zaire ebolavirus (strain Mayinga-76) L Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.9 kDa and the accession number is Q05318.
TMPH-01246	POLR3A Protein, Human, Recombinant (His) RNA polymerase III subunit C160,RNA polyme...	Human	E. coli
	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft ...
TMPH-02384	Lake Victoria marburgvirus (MARV) (strain Popp-67) L Protein (His & Myc) L,Replicase,RNA-directed RNA polymerase L,...	MARV	E. coli
	Lake Victoria marburgvirus (MARV) (strain Popp-67) L Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.7 kDa and the accession number is P35262.
TMPY-03983	CIRBP Protein, Human, Recombinant (His) cold inducible RNA binding protein,CIRP	Human	E. coli
	CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator.CIRBP can bind the 3 translated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for...
TMPH-02356	Influenza A H1N1 (strain A/USA:Huston/AA/1945) Polymerase acidic Protein (His) PA,RNA-directed RNA polymerase subunit P2,...	H1N1	P. pastoris (Yeast)
	Influenza A H1N1 (strain A/USA:Huston/AA/1945) Polymerase acidic Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.6 kDa and the accession number is A4U6V9.
TMPH-02357	Influenza A H3N2 (strain A/X-31) Polymerase acidic Protein (His) Polymerase acidic protein,PA,RNA-directed RNA	H3N2	E. coli
	Influenza A H3N2 (strain A/X-31) Polymerase acidic Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.6 kDa and the accession number is Q9IQ47.
TMPH-03677	Vaccinia virus (strain Copenhagen) OPG065 Protein (His & Myc) OPG065,RNA-binding protein E3,p25,RNA-bind...	VACV	E. coli
	Vaccinia virus (strain Copenhagen) OPG065 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.5 kDa and the accession number is P21081.
TMPH-01247	POLR3K Protein, Human, Recombinant (His) RNA polymerase III subunit C11,POLR3K,RNA ...	Human	Baculovirus Insect Cells
	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase I...
TMPH-03699	VSIV (strain 94GUB Central America) L Protein (His) RNA-directed RNA polymerase L,Replicase,Tr...	VSIV	E. coli
	VSIV (strain 94GUB Central America) L Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.4 kDa and the accession number is Q8B0H0.
TMPH-03735	Zaire ebolavirus (strain Kikwit-95) L Protein (His & Myc) RNA-directed RNA polymerase L,L,Large stru...	ZEBOV	E. coli
	Zaire ebolavirus (strain Kikwit-95) L Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.9 kDa and the accession number is Q6V1Q2.
TMPH-00505	RPB1 Protein, Drosophila melanogaster, Recombinant (His) RNA polymerase II subunit A,DNA-directed RNA	Fruit fly	P. pastoris (Yeast)
	RPB1 Protein, Drosophila melanogaster, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 33.6 kDa and the accession number is P04052.
TMPH-00729	RpoH Protein, E. coli, Recombinant (His & Myc) RNA polymerase sigma-32 factor,Heat shock regulator...	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. Intracellular concentration of free RpoH protein increases in response to heat shock, which causes association with RNA polymerase (RNAP) and initiation of transcription of heat shock genes, including numerous global transcriptional regulators and genes involved in maintaining membrane...
TMPH-00506	NXF2 Protein, Drosophila melanogaster, Recombinant (His) nxf2,Nuclear RNA export factor 2	Fruit fly	Baculovirus Insect Cells
	NXF2 Protein, Drosophila melanogaster, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 33.7 kDa and the accession number is Q9VV73.
TMPH-01110	CIRBP Protein, Human, Recombinant (GST) A18HNRNP,CIRP,Glycine-rich RNA-binding protein CIRP...	Human	E. coli
	CIRBP Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPH-03193	Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO) DNA/RNA-binding protein Alba	Pyrococcus furiosus	E. coli
	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes. Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molec...
TMPH-01900	DDX5 Protein, Human, Recombinant (His & Myc) HELR,RNA helicase p68,HLR1,G17P1,DEAD box protein 5...	Human	E. coli
	DDX5 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 74.1 kDa and the accession number is P17844.
TMPH-02587	CIRBP Protein, Mouse, Recombinant (His) CIRP,A18 hnRNP,Glycine-rich RNA-binding protein CIR...	Mouse	E. coli
	Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN.
TMPH-00728	FliA Protein, E. coli, Recombinant fliA,Sigma-27,Sigma F,Sigma-28,RNA polymerase sigma...	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. FliA Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27.7 kDa and the accession number is P0AEM6.
TMPH-00673	NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His) NAD-capped RNA hydrolase NudC,nudC,NADH pyrophospha...	E. coli	E. coli
	mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates. NADH pyrophosphatase Protein, E. coli O157:H7, Recombina...
TMPH-00727	FliA Protein, E. coli, Recombinant (His) RNA polymerase sigma factor for flagellar operon,Si...	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.
TMPH-01244	POLM Protein, Human, Recombinant (His) DNA-directed DNA/RNA polymerase mu,Terminal transfe...	Human	E. coli
	Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. POLM Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.8 kDa and the accession number is Q9NP87.
TMPH-00102	RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc) RBP47A,RNA-binding protein 47A,Polyadenylate-bindin...	Arabidopsis thaliana	E. coli
	Heterogeneous nuclear ribonucleoprotein (hnRNP)-protein binding the poly(A) tail of mRNA and probably involved in some steps of pre-mRNA maturation. RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.5 kDa and the accession number is F4I3B3.
TMPH-02053	RBM14 Protein, Human, Recombinant (His & SUMO) RNA-binding protein 14,RRM-containing coactivator a...	Human	E. coli
	RBM14 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01249	ADAR Protein, Human, Recombinant (GST) DRADA,K88DSRBP,p136,136 kDa double-stranded RNA-bin...	Human	E. coli
	ADAR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 47.2 kDa and the accession number is P55265.
TMPH-01355	FXR1 Protein, Human, Recombinant (His) FXR1,RNA-binding protein FXR1,FMR1 autosomal homolo...	Human	E. coli
	RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs. FXR1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 70.5 kDa and the accession number is P51114.
TMPH-02380	RPB5 Protein, Kluyveromyces marxianus, Recombinant (His) RPB5,DNA-directed RNA polymerases I, II, and III su...	Kluyveromyces marxianus	E. coli
	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol...
TMPH-01245	POLM Protein, Human, Recombinant (His & Myc) DNA-directed DNA/RNA polymerase mu,POLM,Terminal tr...	Human	Baculovirus Insect Cells
	Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. POLM Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 58.8 kDa and the accession number is Q9NP87.
TMPY-03344	LSM3 Protein, Human, Recombinant (His) SMX4,YLR438C,USS2,LSM3 homolog, U6 small nuclear RNA	Human	E. coli
	LSM3 (LSM3 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. LSM3 is a member of the snRNP Sm proteins family. It plays role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as a component of the pre-catalytic spliceosome (spliceosome B complex). Sm-like proteins can be detected in a variety of organisms. They all have the Sm sequence motif, which consists of 2 regions separated by a linker ...
TMPH-00731	RpoS Protein, E. coli, Recombinant RNA polymerase sigma factor RpoS,rpoS,Sigma S,Sigma...	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. Controls, positively or negatively, the expression of several hundred genes, which are mainly involved in metabolism, transport, regulation and stress management.; Protects stationary phase cells from killing induced by endoribonuclease MazF.
TMPH-00974	DHX9 Protein, Human, Recombinant (His & SUMO) Nuclear DNA helicase II,ATP-dependent RNA helicase ...	Human	E. coli
	DHX9 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01248	ADAR Protein, Human, Recombinant (His & SUMO) ADAR1,IFI-4,136 kDa double-stranded RNA-binding pro...	Human	E. coli
	Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri...
TMPH-00730	RpoS Protein, E. coli, Recombinant (His) Sigma S,rpoS,RNA polymerase sigma factor RpoS,Sigma...	E. coli	E. coli
	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. Controls, positively or negatively, the expression of several hundred genes, which are mainly involved in metabolism, transport, regulation and stress management.; Protects stationary phase cells from killing induced by endoribonuclease MazF.
TMPH-00280	PRKRA Protein, Bovine, Recombinant (His & Myc) Protein kinase, interferon-inducible double-stranded RNA...	Bovine	E. coli
	PRKRA Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.4 kDa and the accession number is Q2HJ92.
TMPH-02133	DDX39B Protein, Human, Recombinant (GST) UAP56,HLA-B-associated transcript 1 protein,DDX39B,ATP-depen...	Human	E. coli
	Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it fun...
TMPH-00980	DHX33 Protein, Human, Recombinant (His) ATP-dependent RNA helicase DHX33,DEAH box protein 3...	Human	E. coli
	DHX33 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01902	DDX60 Protein, Human, Recombinant (His) Probable ATP-dependent RNA helicase DDX60,DEAD box ...	Human	E. coli
	Positively regulates DDX58/RIG-I- and IFIH1/MDA5-dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-I to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV). DDX60 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is Q8IY2...
TMPH-00732	RtcB Protein, E. coli, Recombinant (His) rtcB,3'-phosphate/5'-hydroxy nucleic acid ligase,RNA	E. coli	P. pastoris (Yeast)
	GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splicing 'dirty' DNA breaks, characterized by 3'-phosphate (or cyclic-phosphate) and 5'-hydroxy ends that cannot be sealed by classical DNA ligases.
TMPH-02055	RBPMS Protein, Human, Recombinant (His & Myc) RBPMS,Heart and RRM expressed sequence,RNA-binding ...	Human	E. coli
	Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA. RBPMS Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-...
TMPH-02052	RBMX Protein, Human, Recombinant (GST) Glycoprotein p43,RNA-binding motif protein, X chrom...	Human	E. coli
	RBMX Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPH-00979	DDX3Y Protein, Human, Recombinant (His & Myc) DDX3Y,DBY,DEAD box protein 3, Y-chromosomal,ATP-dependent	Human	Baculovirus Insect Cells
	DDX3Y Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPH-00976	DDX19A Protein, Human, Recombinant (His & SUMO) DDX19L,DDX19A,DDX19-like protein,DEAD box protein 19A,ATP-de...	Human	E. coli
	DDX19A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00973	DHX36 Protein, Human, Recombinant (His & Myc) DEAH-box protein 36,G4R1,ATP-dependent DNA/RNA heli...	Human	E. coli
	DHX36 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.2 kDa and the accession number is Q9H2U1.
TMPH-02884	CTDP1 Protein, Mouse, Recombinant (His & Myc) Fcp1,Ctdp1,RNA polymerase II subunit A C-terminal d...	Mouse	E. coli
	Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation. CTDP1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The p...
TMPH-01460	HNRNPA1 Protein, Human, Recombinant (His) Single-strand RNA-binding protein,hnRNP core protei...	Human	E. coli
	HNRNPA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.9 kDa and the accession number is P09651.
TMPH-01556	EIF2AK2 Protein, Human, Recombinant (His) EIF2AK2,PKR,eIF-2A protein kinase 2,PRKR,p68 kinase,Interfer...	Human	P. pastoris (Yeast)
	EIF2AK2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 64.0 kDa and the accession number is P19525.
TMPH-00975	DDX1 Protein, Human, Recombinant (His & Myc) DBP-RB,DDX1,ATP-dependent RNA helicase DDX1,DEAD bo...	Human	E. coli
	DDX1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01899	ALKBH5 Protein, Human, Recombinant (His) ABH5,Alkylated DNA repair protein alkB homolog 5,RNA	Human	E. coli
	ALKBH5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.2 kDa and the accession number is Q6P6C2.
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重组蛋白

SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His)

Cat.No: TMPY-06071

Species: SARS-CoV-2

Expression System: Baculovirus Insect Cells

T7 RNA polymerase Protein, Enterobacteria phage T7, Recombinant (His & Myc)

Cat.No: TMPH-00533

Species: Escherichia phage T7

Expression System: E. coli

P2 Protein, Pseudomonas phage phi6, Recombinant (His & Myc)

Cat.No: TMPH-03184

Species: Pseudomonas phage phi6

Expression System: E. coli

Zaire ebolavirus (strain Mayinga-76) L Protein (His)

Cat.No: TMPH-03734

Species: ZEBOV

Expression System: E. coli

POLR3A Protein, Human, Recombinant (His)

Cat.No: TMPH-01246

Species: Human

Expression System: E. coli

Lake Victoria marburgvirus (MARV) (strain Popp-67) L Protein (His & Myc)

Cat.No: TMPH-02384

Species: MARV

Expression System: E. coli

CIRBP Protein, Human, Recombinant (His)

Cat.No: TMPY-03983

Species: Human

Expression System: E. coli

Influenza A H1N1 (strain A/USA:Huston/AA/1945) Polymerase acidic Protein (His)

Cat.No: TMPH-02356

Species: H1N1

Expression System: P. pastoris (Yeast)

Influenza A H3N2 (strain A/X-31) Polymerase acidic Protein (His)

Cat.No: TMPH-02357

Species: H3N2

Expression System: E. coli

Vaccinia virus (strain Copenhagen) OPG065 Protein (His & Myc)

Cat.No: TMPH-03677

Species: VACV

Expression System: E. coli

POLR3K Protein, Human, Recombinant (His)

Cat.No: TMPH-01247

Species: Human

Expression System: Baculovirus Insect Cells

VSIV (strain 94GUB Central America) L Protein (His)

Cat.No: TMPH-03699

Species: VSIV

Expression System: E. coli

Zaire ebolavirus (strain Kikwit-95) L Protein (His & Myc)

Cat.No: TMPH-03735

Species: ZEBOV

Expression System: E. coli

RPB1 Protein, Drosophila melanogaster, Recombinant (His)

Cat.No: TMPH-00505

Species: Fruit fly

Expression System: P. pastoris (Yeast)

RpoH Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00729

Species: E. coli

Expression System: E. coli

NXF2 Protein, Drosophila melanogaster, Recombinant (His)

Cat.No: TMPH-00506

Species: Fruit fly

Expression System: Baculovirus Insect Cells

CIRBP Protein, Human, Recombinant (GST)

Cat.No: TMPH-01110

Species: Human

Expression System: E. coli

Alba Protein, Pyrococcus furiosus, Recombinant (His & SUMO)

Cat.No: TMPH-03193

Species: Pyrococcus furiosus

Expression System: E. coli

DDX5 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01900

Species: Human

Expression System: E. coli

CIRBP Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02587

Species: Mouse

Expression System: E. coli

FliA Protein, E. coli, Recombinant

Cat.No: TMPH-00728

Species: E. coli

Expression System: E. coli

NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His)

Cat.No: TMPH-00673

Species: E. coli

Expression System: E. coli

FliA Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00727

Species: E. coli

Expression System: E. coli

POLM Protein, Human, Recombinant (His)

Cat.No: TMPH-01244

Species: Human

Expression System: E. coli

RBP47A Protein, Arabidopsis thaliana, Recombinant (His & Myc)

Cat.No: TMPH-00102

Species: Arabidopsis thaliana

Expression System: E. coli

RBM14 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02053

Species: Human

Expression System: E. coli

ADAR Protein, Human, Recombinant (GST)

Cat.No: TMPH-01249

Species: Human

Expression System: E. coli

FXR1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01355

Species: Human

Expression System: E. coli

RPB5 Protein, Kluyveromyces marxianus, Recombinant (His)

Cat.No: TMPH-02380

Species: Kluyveromyces marxianus

Expression System: E. coli

POLM Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01245

Species: Human

Expression System: Baculovirus Insect Cells

LSM3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03344

Species: Human

Expression System: E. coli

RpoS Protein, E. coli, Recombinant

Cat.No: TMPH-00731

Species: E. coli

Expression System: E. coli

DHX9 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-00974

Species: Human

Expression System: E. coli

ADAR Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01248

Species: Human

Expression System: E. coli

RpoS Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00730

Species: E. coli

Expression System: E. coli

PRKRA Protein, Bovine, Recombinant (His & Myc)

Cat.No: TMPH-00280

Species: Bovine

Expression System: E. coli

DDX39B Protein, Human, Recombinant (GST)

Cat.No: TMPH-02133

Species: Human

Expression System: E. coli

DHX33 Protein, Human, Recombinant (His)

Cat.No: TMPH-00980

Species: Human

Expression System: E. coli

DDX60 Protein, Human, Recombinant (His)

Cat.No: TMPH-01902

Species: Human

Expression System: E. coli

RtcB Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00732

Species: E. coli

Expression System: P. pastoris (Yeast)

RBPMS Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02055

Species: Human

Expression System: E. coli

RBMX Protein, Human, Recombinant (GST)

Cat.No: TMPH-02052

Species: Human

Expression System: E. coli

DDX3Y Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00979

Species: Human

Expression System: Baculovirus Insect Cells

DDX19A Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-00976

Species: Human

Expression System: E. coli

DHX36 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00973

Species: Human

Expression System: E. coli

CTDP1 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02884

Species: Mouse

Expression System: E. coli

HNRNPA1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01460

Species: Human

Expression System: E. coli

EIF2AK2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01556

Species: Human

Expression System: P. pastoris (Yeast)

DDX1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00975

Species: Human

Expression System: E. coli

ALKBH5 Protein, Human, Recombinant (His)

Cat.No: TMPH-01899

Species: Human

Expression System: E. coli

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Cat. No.	Product Name	Target	Signaling Pathways
TMID-0227	Rifabutin-d7
	Rifabutin-d7 是 Rifabutin 的氘代化合物。Rifabutin 的 CAS 号为 72559-06-9。Rifabutin是半合成的安莎霉素抗生素，抑制 DNA 依赖性 RNA 聚合酶，有抗分枝杆菌作用。
TMID-0286	Rifaximin-d6
	Rifaximin-d6 是 Rifaximin 的氘代化合物。Rifaximin 的 CAS 号为 80621-81-4。Rifaximin是一种胃肠道选择性抗生素，与细菌 DNA 依赖性 RNA 聚合酶的 β 亚基结合，抑制细菌 RNA 合成。与革兰氏阴性菌（MIC：8-50 毫克/毫升）相比，它对革兰氏阳性菌株（MIC：0.03-5 毫克/毫升）的敏感性更高。
T12955	Sofosbuvir D6 PSI-7977 D6,GS-7977 D6	Others	Others
	Sofosbuvir D6 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
T12135	Mycophenolic acid-d3 Mycophenolate-d3,Mycophenolate D3	Others; Antibacterial	Microbiology/Virology; Others
	Mycophenolic acid-d3 (Mycophenolate-d3) 是 Mycophenolic acid 的衍生物。Mycophenolic acid 是一种降低GTP 水平和损害RNA 聚合酶II (RNAP II)转录延伸的化合物，促进了近端位点的使用，能够逆转虫草素对选择性聚腺苷化的作用。
TMID-0065	Adenine-2-d1
	Adenine-2-d1 是 Adenine 的氘代化合物。Adenine 的 CAS 号为 73-24-5。Adenine 是一种嘌呤衍生物，是一种核碱基。它在细胞呼吸、以富含能量的 ATP 和 NAD 和 FAD 的形式和蛋白质合成作用，作为 DNA 和 RNA 的化学成分。
TMIH-0091	AOH-d3
	AOH-d3 是 AOH 的氘代化合物。AOH 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体，靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用，导致 DNA 复制应激，诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用，可抑制肿瘤细胞生长。
T38297	Ribavirin-13C5 Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...
TMID-0242	Capecitabine-d11
	Capecitabine-d11 是 Capecitabine 的氘代化合物。Capecitabine 的 CAS 号为 154361-50-9。Capecitabine 是一种可口服的前药，可由胸苷磷酸化酶催化转变为其活性代谢物 Fluorouracil。
T36895	5-Fluorouracil-13C,15N2 5-Fluorouracil-13C,15N2
	5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
TMIH-0025	13C-d3-AOH1996
	13C-d3-AOH1996 是 AOH1996 的 13C 和氘代化合物。AOH1996 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体，靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用，导致 DNA 复制应激，诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用，可抑制肿瘤细胞生长。
TMID-0076	Busulfan-d8
	Busulfan-d8 是 Busulfan 的氘代化合物。Busulfan 的 CAS 号为 55-98-1。Busulfan 是二甲磺酸盐的合成衍生物，具有抗肿瘤和细胞毒特性。是一种烷化剂，对骨髓具有选择性免疫抑制作用。
T71401	Oxaliplatin-d10
	Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2....
TMID-0166	Thymine-d4
	Thymine-d4 是 Thymine 的氘代化合物。Thymine 的 CAS 号为 65-71-4。Thymine 是 DNA 的四个碱基之一，在动物癌症模型中，能够作为5-氟尿嘧啶的靶标，其 Km=2.3 μM。
TMIJ-0331	Amantadine-d15 Hydrochloride
	Amantadine-d15 Hydrochloride 是 Amantadine Hydrochloride 的氘代化合物。Amantadine Hydrochloride 的 CAS 号为 665-66-7。Amantadine hydrochloride是一种抗病毒药物，用于预防或对症治疗甲型流感和帕金森病。它阻断质子流通过 M2 离子通道，从而阻止病毒 RNA 释放到感染细胞的细胞质中。
TMIH-0105	Baloxavir-d4
	Baloxavir-d4 是 Baloxavir 的氘代化合物。Baloxavir 的 CAS 号为 1985605-59-1。Baloxavir 是衍生自前药 Baloxavir marboxil，是流感病毒聚合酶 PA 亚基的一流帽依赖性核酸内切酶抑制剂。它抑制病毒 RNA 的转录和复制，具有强大的抗病毒活性。
TMIJ-0087	Mycophenolic acid-13C-d3
	Mycophenolic acid-13C-d3 是 Mycophenolic acid 的 13C 和氘代化合物。Mycophenolic acid 的 CAS 号为 24280-93-1。Mycophenolic acid 是一种有效的非竞争性肌苷单磷酸脱氢酶 (IMPDH) 抑制剂，EC50为 0.24 µM。它对多种 RNA 病毒具有抗病毒作用。它也是一种免疫抑制剂，具有抗血管生成和抗肿瘤作用。

同位素标记化合物

Cat.No: TMID-0227

Cat.No: TMID-0286

Cat.No: T12955

Synonym: PSI-7977 D6,GS-7977 D6

Target: Others

Mycophenolic acid-d3

Cat.No: T12135

Synonym: Mycophenolate-d3,Mycophenolate D3

Target: Others, Antibacterial

Cat.No: TMID-0065

Cat.No: TMIH-0091

Cat.No: T38297

Synonym: Ribavirin-13C5

Capecitabine-d11

Cat.No: TMID-0242

5-Fluorouracil-13C,15N2

Cat.No: T36895

Synonym: 5-Fluorouracil-13C,15N2

Cat.No: TMIH-0025

Cat.No: TMID-0076

Oxaliplatin-d10

Cat.No: T71401

Cat.No: TMID-0166

Amantadine-d15 Hydrochloride

Cat.No: TMIJ-0331

Cat.No: TMIH-0105

Mycophenolic acid-13C-d3

Cat.No: TMIJ-0087

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