Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70523 |
RK-682
|
Others | Others |
RK-682 is a natural selective inhibitor of protein tyrosine phosphatases (PTPases). | |||
T41370 |
(Rac)-RK-682
|
Others | Others |
(Rac)-RK-682 是 RK-682 的外消旋体。(Rac)-RK-682 是一种蛋白质酪氨酸磷酸酶 (PTPases) 抑制剂。(Rac)-RK-682 抑制蛋白酪氨酸磷酸酶 1B (PTP-1B)、低分子量蛋白酪氨酸磷酸酶 (LMW-PTP)、细胞分裂周期 25B (CDC-25B),IC50分别为 8.6 μM、12.4 μM 和 0.7 μM。 | |||
T36367 |
RK-682 (calcium salt)
|
Others | Others |
Protein tyrosine phosphatases (PTPs) remove phosphate from tyrosine residues of cellular proteins. Reversible phosphorylation catalyzed by the coordinated actions of protein tyrosine kinases and phosphatases is key to the regulation of the signaling events that control cell growth and proliferation, differentiation, and survival or apoptosis, as well as adhesion and motility. RK-682, a bioactive compound originally isolated from the fermentation of Streptomyces sp. 88-682, is an inhibitor of the... | |||
T70521 |
CGP-49823
|
Others | Others |
CGP-49823 is a non-peptide tachykinin NK1 receptor antagonist. |