Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T71457 |
RGH-618
|
Others | Others |
RGH-618 is an agonist of metabotropic glutamate receptor types 1 and 5, for the treatment of anxiety disorders. | |||
T71998 |
673-A
|
Others | Others |
673-A is an aldehyde dehydrogenase (ALDH1A) inhibitor that depletes CD133+ cancer stem cells (CSC) in ovarian cancer cell lines. 673-A triggers necroptosis in ovarian CSCs and induces expression of mitochondrial uncoupling proteins (UCP). 673-A also overcomes chemotherapy resistance in vivo. |