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Search Results for " rabv "
Targets Recommended: Others

5

抑制剂 & 化合物

1

天然产物

12

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T8701 GRP-60367

Others Others
GRP-60367 是一种小分子狂犬病病毒进入抑制剂,对某些 RABV 株具有纳摩尔作用效果。
T61763 GRP-60367 hydrochloride

Others Others
GRP-60367 hydrochloride is a novel small-molecule entry inhibitor of rabies virus (RABV), exhibiting nanomolar potency against select RABV strains. This first-in-class compound effectively targets the RABV G protein [1].
T77137 Rafivirumab

Rafivirumab (CR57) 是一种用于预防狂犬病的抗狂犬病病毒 (rabies virus) 单克隆抗体。Rafivirumab 对广泛的 RABV 变体具有中和效力。Rafivirumab 可用于鸡尾酒疗法的研究。
T77081 Mazorelvimab

Mazorelvimab (SYN023) 是一种由 CTB011 和 CTB012 组成的抗狂犬病病毒 (RABV) 人源化单克隆抗体混合型。Mazorelvimab 可与RABV 糖蛋白 (G) 上的非重叠表位结合。Mazorelvimab 在预防狂犬病中有潜在应用。
T80589 Zamerovimab

SYN023,CTB011

Zamerovimab (CTB011; SYN023) 是一种由 CTB011 和 CTB012 组成的人源化单克隆抗体混合物,能与狂犬病病毒 (RABV) 糖蛋白的非重叠表位发生结合,且 CTB011 特异性结合抗原位点III。该混合物适用于狂犬病相关研究。

化合物

GRP-60367
Cat.No: T8701
Synonym:
Target: Others
GRP-60367 hydrochloride
Cat.No: T61763
Synonym:
Target: Others
Rafivirumab
Cat.No: T77137
Synonym:
Target:
Mazorelvimab
Cat.No: T77081
Synonym:
Target:
Zamerovimab
Cat.No: T80589
Synonym: SYN023,CTB011
Target:
Cat. No. Product Name Target Signaling Pathways
T3794 Pentagalloylglucose

Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖

Influenza Virus Microbiology/Virology
1,2,3,4,6-O-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) 存在于多种植物中,具有重要的药理作用。Pentagalloylglucose 表现出显著的抗狂犬病病毒 (RABV) 活性。

天然产物

Pentagalloylglucose
Cat.No: T3794
Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖
Target: Influenza Virus
Cat. No. Product Name Species Expression System
TMPH-03222 Rabies virus (RABV) (strain ERA) Glycoprotein (His)

Glycoprotein,G

RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03219 Rabies virus (RABV) (strain India) Glycoprotein (His)

Glycoprotein,G

RABV P. pastoris (Yeast)
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03220 Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO)

Glycoprotein,G

RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03226 Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST)

Phosphoprotein M2,Matrix protein,M

RABV E. coli
Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 49.9 kDa and the accessio...
TMPH-03229 Rabies virus (RABV) (strain PM) Phosphoprotein (His)

P,Protein M1,Phosphoprotein

RABV E. coli
Rabies virus (RABV) (strain PM) Phosphoprotein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.2 kDa and the accession number is P69480.
TMPH-03223 Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His)

G,Glycoprotein

RABV Baculovirus Insect Cells
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPH-03228 Rabies virus (RABV) (strain SAD B19) Matrix Protein (His)

Nucleoprotein,Nucleocapsid protein,N

RABV E. coli
Rabies virus (RABV) (strain SAD B19) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.7 kDa and the accession number is P16285.
TMPH-03225 Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc)

Matrix protein,M,Phosphoprotein M2

RABV E. coli
Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa an...
TMPH-03224 Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His)

G,Glycoprotein

RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...
TMPY-06619 Rabies virus(RABV) (strain CVS-11) Nucleoprotein/NP Protein (His)

RABV E. coli
Rabies virus(RABV) (strain CVS-11) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 51.69 kDa and the accession number is Q8JXF6.
TMPH-03227 Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His)

Nucleoprotein,Nucleocapsid protein,N

RABV E. coli
Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.7 kDa and the accession number is P15197.
TMPH-03221 Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO)

G,Glycoprotein

RABV E. coli
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie...

重组蛋白

Rabies virus (RABV) (strain ERA) Glycoprotein (His)
Cat.No: TMPH-03222
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain India) Glycoprotein (His)
Cat.No: TMPH-03219
Species: RABV
Expression System: P. pastoris (Yeast)
Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO)
Cat.No: TMPH-03220
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST)
Cat.No: TMPH-03226
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain PM) Phosphoprotein (His)
Cat.No: TMPH-03229
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His)
Cat.No: TMPH-03223
Species: RABV
Expression System: Baculovirus Insect Cells
Rabies virus (RABV) (strain SAD B19) Matrix Protein (His)
Cat.No: TMPH-03228
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc)
Cat.No: TMPH-03225
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His)
Cat.No: TMPH-03224
Species: RABV
Expression System: E. coli
Rabies virus(RABV) (strain CVS-11) Nucleoprotein/NP Protein (His)
Cat.No: TMPY-06619
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His)
Cat.No: TMPH-03227
Species: RABV
Expression System: E. coli
Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO)
Cat.No: TMPH-03221
Species: RABV
Expression System: E. coli
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