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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8701 |
GRP-60367
|
Others | Others |
GRP-60367 是一种小分子狂犬病病毒进入抑制剂,对某些 RABV 株具有纳摩尔作用效果。 | |||
T61763 |
GRP-60367 hydrochloride
|
Others | Others |
GRP-60367 hydrochloride is a novel small-molecule entry inhibitor of rabies virus (RABV), exhibiting nanomolar potency against select RABV strains. This first-in-class compound effectively targets the RABV G protein [1]. | |||
T77137 | Rafivirumab | ||
Rafivirumab (CR57) 是一种用于预防狂犬病的抗狂犬病病毒 (rabies virus) 单克隆抗体。Rafivirumab 对广泛的 RABV 变体具有中和效力。Rafivirumab 可用于鸡尾酒疗法的研究。 | |||
T77081 | Mazorelvimab | ||
Mazorelvimab (SYN023) 是一种由 CTB011 和 CTB012 组成的抗狂犬病病毒 (RABV) 人源化单克隆抗体混合型。Mazorelvimab 可与RABV 糖蛋白 (G) 上的非重叠表位结合。Mazorelvimab 在预防狂犬病中有潜在应用。 | |||
T80589 |
Zamerovimab
SYN023,CTB011 |
||
Zamerovimab (CTB011; SYN023) 是一种由 CTB011 和 CTB012 组成的人源化单克隆抗体混合物,能与狂犬病病毒 (RABV) 糖蛋白的非重叠表位发生结合,且 CTB011 特异性结合抗原位点III。该混合物适用于狂犬病相关研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3794 |
Pentagalloylglucose
Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖 |
Influenza Virus | Microbiology/Virology |
1,2,3,4,6-O-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) 存在于多种植物中,具有重要的药理作用。Pentagalloylglucose 表现出显著的抗狂犬病病毒 (RABV) 活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03222 |
Rabies virus (RABV) (strain ERA) Glycoprotein (His)
Glycoprotein,G |
RABV | E. coli |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie... | |||
TMPH-03219 |
Rabies virus (RABV) (strain India) Glycoprotein (His)
Glycoprotein,G |
RABV | P. pastoris (Yeast) |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie... | |||
TMPH-03220 |
Rabies virus (RABV) (strain India) Glycoprotein (His & SUMO)
Glycoprotein,G |
RABV | E. coli |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie... | |||
TMPH-03226 |
Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST)
Phosphoprotein M2,Matrix protein,M |
RABV | E. coli |
Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 49.9 kDa and the accessio... | |||
TMPH-03229 |
Rabies virus (RABV) (strain PM) Phosphoprotein (His)
P,Protein M1,Phosphoprotein |
RABV | E. coli |
Rabies virus (RABV) (strain PM) Phosphoprotein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.2 kDa and the accession number is P69480. | |||
TMPH-03223 |
Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (His)
G,Glycoprotein |
RABV | Baculovirus Insect Cells |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie... | |||
TMPH-03228 |
Rabies virus (RABV) (strain SAD B19) Matrix Protein (His)
Nucleoprotein,Nucleocapsid protein,N |
RABV | E. coli |
Rabies virus (RABV) (strain SAD B19) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.7 kDa and the accession number is P16285. | |||
TMPH-03225 |
Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc)
Matrix protein,M,Phosphoprotein M2 |
RABV | E. coli |
Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Rabies virus (RABV) (strain CVS-11) Matrix Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa an... | |||
TMPH-03224 |
Rabies virus (RABV) (strain HEP-Flury) Glycoprotein (E. coli, His)
G,Glycoprotein |
RABV | E. coli |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie... | |||
TMPY-06619 |
Rabies virus(RABV) (strain CVS-11) Nucleoprotein/NP Protein (His)
|
RABV | E. coli |
Rabies virus(RABV) (strain CVS-11) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 51.69 kDa and the accession number is Q8JXF6. | |||
TMPH-03227 |
Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His)
Nucleoprotein,Nucleocapsid protein,N |
RABV | E. coli |
Rabies virus (RABV) (strain PM1503/AVO1) Matrix Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.7 kDa and the accession number is P15197. | |||
TMPH-03221 |
Rabies virus (RABV) (strain CVS-11) Glycoprotein (His & Myc & SUMO)
G,Glycoprotein |
RABV | E. coli |
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. Rabie... |