87
3
53
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2467 |
R406 free base
R406 (free base) |
Apoptosis; FLT; Syk | Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors |
R406 free base (R406(free base)) 是一种具有口服活性的,ATP 竞争性的Syk/FLT3抑制剂,Ki 为 30 nM。它有效抑制 Syk 激酶活性,IC50为 41 nM,可减轻免疫复合物介导的炎症。它还抑制 Lyn 和 Lck,IC50分别为 63 nM 和 37 nM。 | |||
T11669 |
IR415
|
HBV | Microbiology/Virology |
IR415 选择性地与 HBx 相互作用 (Kd=2 nM) 并阻断 HBV 介导的 RNAi 抑制,逆转 HBx 蛋白对 Dicer 核糖核酸内切酶活性的抑制作用。IR415 具有抗 HBV 的活性。 | |||
T2268 |
VER49009
CCT0129397,VER 49009,VER-49009 |
HSP | Cytoskeletal Signaling; Metabolism |
VER49009 (CCT0129397) 是一种有效的 HSP90 抑制剂(IC50 =25 nM,Kd=78 nM)。 | |||
T26647 |
AR420626
AR 420626,AR-420626 |
Others | Others |
AR420626 是一种选择性脂肪酸 3 受体 (FA3R) 激动剂,对被选择性 FA3R 拮抗剂 β-羟基丁酸酯 (BHB) 完全阻断的猪甲酚 (SALS) 提供保护作用。 | |||
T11458 |
GPR40/FFAR1 modulator 1
|
GPR | Endocrinology/Hormones; GPCR/G Protein |
GPR40/FFAR1 modulator 1是一种针对Gq偶联的游离脂肪酸受体1 (GPR40/FFAR1) 的激动剂以及异构调节剂。 | |||
T34705 |
SR4554
SR 4554 |
Others | Others |
SR4554 是通过 19F 磁共振波谱 (MRS) 检测到的含氟 2-硝基咪唑无创肿瘤缺氧探针,用于检测肿瘤缺氧。 | |||
T6392 |
AR42
OSU-HDAC42,AR-42,(S)-(+)-N-羟基-4-(3-甲基-2-苯基丁酰氨基)苯甲酰胺,AR 42,HDAC-42 |
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
AR42 (OSU-HDAC42) 是一种 HDAC 抑制剂(IC50: 30 nM)。 | |||
T23308 |
SAR407899 hydrochloride
6-(哌啶-4-氧基)异喹啉-1(2H)-酮盐酸盐 |
ROCK | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
SAR407899 hydrochloride 是一种选择性,ATP 竞争性的ROCK 抑制剂,对人和大鼠ROCK2的Ki 值分别为 36 和 41 nM,对ROCK2的IC50值为 135 nM。 | |||
T6174 |
R406
R-406 besylate |
Apoptosis; FLT; Syk | Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors |
R406 (R-406 besylate) 是一种具有口服活性的 ATP 竞争性 Syk/FLT3抑制剂,Ki 为 30 nM。它有效抑制 Syk 激酶活性,IC50为 41 nM。它还抑制 Lyn 和 Lck,IC50值分别为 63 nM 和 37 nM。它可减轻免疫复合物介导的炎症。 | |||
T15010 |
CR4056
6-(1H-imidazol-1-yl)-2-phenylquinazoline |
MAO; Imidazoline Receptor | Metabolism; Neuroscience |
CR4056 (6-(1H-imidazol-1-yl)-2-phenylquinazoline) 是一种特异性 MAO-A 抑制剂,IC50 为 202.7 nM,是 I2-咪唑啉受体的配体,IC50 为 596 nM。 | |||
T12831 |
SAR405 R enantiomer
|
Others | Others |
SAR405 R enantiomer 是一种 PIK3C3/Vps34 抑制剂,也是活性低于 SAR405 的对映体。 | |||
T12831L |
SAR405
|
PI3K; Autophagy | Autophagy; PI3K/Akt/mTOR signaling |
SAR-405 是一种选择性 PIK3C3/Vps34 抑制剂,IC50为1.2 nM,Kd 为1.5 nM,可防止自噬并与肿瘤细胞中的 MTOR 抑制协同作用。它抑制饥饿或 mTOR 抑制诱导的自噬,具有抗癌活性。 | |||
TQ0256 |
FGFR4-IN-1
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR4-IN-1 是一种 FGFR4 抑制剂 (IC50:0.7 nM)。 | |||
T8740 |
COH-SR4
COH-SR4 (Mitochondria uncoupler SR4) |
Others; AMPK | Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling |
COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) 是线粒体氧化磷酸化的解偶联剂,可调节 amp 依赖性激酶 (ampk)-雷帕霉素 (mtor) 信号的哺乳动物靶点,并抑制 hepg2 肝癌细胞的增殖。它对白血病、黑色素瘤、乳腺癌和肺癌显示出强大的抗增殖活性。它是一种AMPK 活化剂,通过激活 AMPK 来抑制脂肪细胞分化,可用于肥胖及代谢紊乱相关的研究。 | |||
T6585 |
SAR405838
MI773,MI 773,MI-77301,MI-773 |
Mdm2; E1/E2/E3 Enzyme | Apoptosis; Ubiquitination |
SAR405838 (MI 773) 是 MI-773 的类似物,具有抗肿瘤活性。它是一种高效、选择性的MDM2-p53相互作用抑制剂,与 MDM2 结合的Ki 值为 0.88 nM。 | |||
T7672 |
MD2-TLR4-IN-1
|
TLR | Immunology/Inflammation |
MD2-TLR4-IN-1 是一种骨髓分化蛋白 2/toll 样受体 4 (MD2-TLR4) 复合物抑制剂,能够抑制巨噬细胞 LPS 诱导的 TNF-α 和 IL-6 的表达,IC50值分别为 0.89 和 0.53 μM。 | |||
T7391 |
SAR407899
|
ROCK; Rho | Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
SAR407899 是一种选择性的 ATP 竞争性ROCK 抑制剂,对ROCK-2的IC50值为 135 nM,对人和大鼠ROCK-2的Ki 值分别为 36 和 41 nM。它是 Rho 激酶抑制剂,有效抑制 endothelin-1 诱导的肾阻力动脉收缩。 | |||
T8503 |
TLR4-IN-C34
|
TLR | Immunology/Inflammation |
TLR4-IN-C34 是 TLR4 的抑制剂,可减少内毒素血症和坏死性小肠结肠炎模型中的全身炎症 | |||
T60336 |
CCR4 antagonist 3-1
|
CCR | Immunology/Inflammation; Microbiology/Virology |
CCR4 antagonist 3-1 是一种具有较低活性的趋化因子受体 4 (CCR4) 拮抗剂,对 [125I]TARC (胸腺和活化调节趋化因子) 具有抑制作用,IC50 值为 1.7 μM。CCR4 antagonist 3-1 对放射标记的[125I]TARC和巨噬细胞来源的趋化因子(MDC) 与 CEM 细胞表面的CCR4 受体的结合有抑制作用, 并对 TARC 介导的 CEM 细胞的体外迁移有抑制作用,IC50 值为 6.4 μM。 | |||
T76590 |
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin
|
||
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin,是一种催产素受体拮抗剂,可消除 CA1 锥体神经元中催产素增强的抑制性突触后电流。 | |||
T76616 |
(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
|
||
(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH 是一种黄体生成素释放激素 (LHRH) 的类似物,主要通过促进垂体分泌黄体生成素 (LH) 和促卵泡激素 (FSH) 来在生殖调控中发挥关键作用。 | |||
T10507 |
GPR40 Agonist 2
|
GPR | Endocrinology/Hormones; GPCR/G Protein |
GPR40 Agonist 2 is a GPR40 agonist. It can be used in the research of diabetes. | |||
T11459 |
GPR40 agonist 1
|
Others | Others |
GPR40 agonist 1 is an effective new GPR40 agonist (EC50s: 17 nM and 2 nM for rGPR40 and hGPR40). | |||
T81214 |
SAR441255
|
||
SAR441255为高效单分子肽GLP-1/GIP/GCG受体激动剂,能平衡激活三种靶受体,表现出高效力。此外,SAR441255对糖尿病肥胖猴子具有显著的急性血糖调节效果。 | |||
T22750 |
DR4485 hydrochloride
DR 4485 hydrochloride |
Others | Others |
5-HT7 antagonist | |||
T61650 |
CXCR4 antagonist 9
|
Others | Others |
CXCR4 antagonist 9 (Compound 2) is a potent CXCR4 antagonist displaying an IC50 of 15 nM. It effectively inhibits the cytosolic calcium increase induced by CXCL12, with an IC50 value of 1.3 nM [1]. | |||
T28957 |
TFR4OHT
TFR-4-OHT,TFR 4 OHT |
Others | Others |
TFR4OHT is a selective ER modulator (SERM). | |||
T74387 |
Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH
|
Others | Others |
Tri(TLR4-IN-C34-C2-amide-PEG1)-amide-C3-COOH为包括TLR4抑制剂TLR4-IN-C34的连接子。该化合物通过抑制肠细胞与巨噬细胞内TLR4活性,能够减轻内毒素血症及坏死性小肠结肠炎小鼠模型中的全身性炎症。 | |||
T80977 |
TLR4 agonist-1 TEA
|
Others | Others |
TLR4agonist-1 (TEA) (compound 17a)为Toll-like Receptor 4 (TLR4)的高效激动剂,在RAW 264.7及MM6细胞中能有效促进MIP-1β的生成。 | |||
T60811 |
CXCR4 antagonist 7
|
Others | Others |
CXCR4 antagonist 7 (Compound PARA-B) 是可用于研究HIV 感染、炎症性疾病、癌症和 WHIM 综合症的CXCR4拮抗剂 (IC50 = 9.3 nM)。 | |||
T63692 |
FGFR4-IN-7
|
Others | Others |
FGFR4-IN-7 是共价的、可逆的 FGFR4 抑制剂 (IC50: 0.42 μM),能够阻断 FGFR4 信号通路,进而诱导细胞凋亡 (apoptosis)。FGFR4-IN-7 能够用于研究肝癌 (HCC)。 | |||
T80978 |
TLR4 agonist-1
|
Others | Others |
TLR4agonist-1 (compound 17a)是一种针对Toll-like Receptor 4 (TLR4)的高效激动剂,能有效激发RAW 264.7与MM6细胞产生MIP-1β。 | |||
T76483 |
[Sar4] Substance P (4-11)
|
||
[Sar4] Substance P (4-11)为Substance P (4-11)的类似物,后者是Substance P (Substance P) C端片段并充当Substance P激动剂。 | |||
T63369 |
CXCR4 antagonist 4
|
||
CXCR4 antagonist 4 是口服具有活力的、有效的CXCR4拮抗剂,IC50 值为 24 nM。CXCR4 antagonist 4能够抑制 CYP 2D6 的活性,增加 PAMPA 的通透性,有效阻碍人类免疫缺陷病毒的进入 (IC50=7 nM)。 | |||
T11280 |
FGFR4-IN-4
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity. | |||
T61409 |
CXCR4 antagonist 3
|
Others | Others |
CXCR4 antagonist 3 (compound 12a), an effective antagonist of CXCR4, exhibits an IC50 of 11 nM. It is a congener of TIQ15, showcasing exceptional properties such as CXCR4 antagonism, CYP 2D6 inhibition, metabolic stability, and permeability. With its potential for research on the human immunodeficiency virus, CXCR4 antagonist 3 holds great promise [1]. | |||
T34421 |
RSR4
RSR 4,RSR-4 |
Others | Others |
RSR4 is one of the most effective allosteric effectors of hemoglobin. | |||
T74389 |
Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH
|
Others | Others |
Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH 是一种融合了TLR4-IN-C34抑制剂的连接子。这种抑制剂在阻断肠细胞与巨噬细胞内的TLR4上发挥作用,有效减轻了内毒素血症及坏死性小肠结肠炎小鼠模型中的全身性炎症现象。 | |||
T62542 |
GPR40 agonist 5
|
Others | Others |
GPR40 agonist 5 是一种口服具有活力的 GPR40 (G 蛋白偶联受体 40) 激动剂 (EC50: 47 nM)。GPR40 agonist 5 能够减少血糖水平,改善糖耐量。GPR40 agonist 5 对 2 型糖尿病小鼠的高血糖状态表现出充足的控制作用。 | |||
T61363 |
CXCR4 antagonist 8
|
Others | Others |
CXCR4 antagonist 8 (Compound 3) is a potent inhibitor of CXCR4. It demonstrates an IC50 value of 57 nM in CXCR4 antagonism. In addition, it effectively inhibits the increase in cytosolic calcium induced by CXCL12 with an IC50 value of 0.24 nM. Furthermore, Compound 3 shows efficacy in the inhibition of CXCL12/CXCR4-mediated cell migration [1]. | |||
T78879 |
CXCR4-IN-2
|
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
CXCR4-IN-2(compound A1)是一款具有抗癌活性的双功能氟化小分子,是CXCR4的强效抑制剂。它对小鼠结直肠癌(CRC)细胞展现出显著的细胞毒性(IC50:60 μg/mL;72小时)和抗增殖能力,能够引导细胞在G2/M期发生阻滞并诱导细胞凋亡(apoptosis)。 | |||
T79880 |
FGFR4-IN-16
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR4-IN-16 (CY-15-2)为FGFR-4选择性共价抑制剂,适用于癌症研究领域。 | |||
T39661 |
CCR4 antagonist 3
CCR4 antagonist 3 |
Others | Others |
CCR4 antagonist 3 is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antagonist 3 has antitumor activity. | |||
T64583 |
Phospho-Akt (Ser473) Antibody #9271R
|
Others | Others |
Phospho-Akt (Ser473) Antibody #9271R 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64583。 | |||
T34913 |
TR4161
TR 4161,TR-4161 |
Others | Others |
TR4161 is a prostaglandin bronchodilator of low tracheobronchial irritancy. | |||
T28849 |
SR48527
SR-48527,SR 4852 |
Others | Others |
SR48527 is a selective antagonist of NTS1R. | |||
T74388 |
Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
|
Others | Others |
Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH 是一种含有 TLR4抑制剂 TLR4-IN-C34 的连接子。TLR4-IN-C34 抑制肠细胞和巨噬细胞中的TLR4,减少内毒素血症和坏死性小肠结肠炎小鼠模型的全身炎症。 | |||
T62816 |
NVP-CLR457
|
Others | Others |
NVP-CLR457 (compound 40) 是一种口服具有活力的、平衡的泛 I 类 PI3K 抑制剂,具有抗肿瘤作用。NVP-CLR457 表现出显著的剂量依赖性 PK / PD / 疗效关系。 | |||
T39662 |
CCR4 antagonist 3 hydrochloride
|
Others | Others |
CCR4 antagonist 3 hydrochloride is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antagonist 3 has antitumor activity. | |||
T62359 |
TLR4/NF-κB/MAPK-IN-1
|
Others | Others |
TLR4/NF-κB/MAPK-IN-1通过抑制 TLR4/NF-kB/MAPK 途径,是一种新型抗神经炎症剂。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN2296 |
Vinaginsenoside R4
越南参皂苷R4 |
Others | Others |
Vinaginsenoside R4 是分离自水培人参的叶子中。它能够抑制黑色素的生物合成,并增强斑马鱼的色素沉着,对 melan-a 细胞没有任何细胞毒性作用。 | |||
TN6691 |
Notoginsenoside R4
|
||
Notoginsenoside R4 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6691,CAS号为 87741-77-3。 | |||
T3S1589 |
Notoginsenoside Fa
|
Others | Others |
Notoginsenoside Fa 是一种原人参二醇型皂苷,从P. notoginseng 提取出来得到,有激活和恢复退化脑功能的潜能。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05481 |
DcR2/TRAIL R4 Protein, Human, Recombinant (hFc)
TRUNDD,TRAIL-R4,tumor necrosis factor receptor supe... |
Human | HEK293 Cells |
DcR2/TRAIL R4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.5 kDa and the accession number is Q9UBN6. | |||
TMPY-01381 |
DcR2/TRAIL R4 Protein, Human, Recombinant (His)
CD264,TRAILR4,tumor necrosis factor receptor superf... |
Human | HEK293 Cells |
DcR2/TRAIL R4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is Q9UBN6. | |||
TMPY-01359 |
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin ... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2. | |||
TMPY-00850 |
ST2/IL-1 RL1 Protein, Human, Recombinant
ST2,IL1RL1,ST2L,IL33R,T1,DER4,ST2V,IL‑1 R4... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2. | |||
TMPY-00849 |
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
ST2V,FIT-1,DER4,interleukin 1 receptor-like 1,T1,IL... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2. | |||
TMPJ-00850 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Protein T1,suppression of tumorigenicity 2,Ly84,DER4 |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. | |||
TMPK-00694 |
CD1A Protein, Human, Recombinant (His)
CD1,HTA1,FCB6,T6,R4,CD1a |
Human | HEK293 Cells |
CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tails (CTs) of all human CD1 isoforms, with the exception of CD1a, contain tyrosine-based sorting motifs, responsible for the internalization of proteins by the clathrin-mediated pathway. CD1a closer to MHC class I in its trafficking and potential antigen-loading compartments among CD1 isoforms. | |||
TMPK-00379 |
FGFR4 Protein, Human, Recombinant (His & Avi)
CD334,FGFR4,TKF,FGF R4,FGFR-4,MGC20292,JTK... |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1. | |||
TMPK-00381 |
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
CD334,FGFR-4,FGFR4,FGF R4,TKF,JTK2,MGC2029... |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1. | |||
TMPK-01322 |
FGFR4 Protein, Rhesus macaque, Recombinant (His)
TKF,JTK2,FGF R4,CD334,FGFR-4,FGFR4,MGC2029... |
Rhesus | HEK293 Cells |
FGFR4 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.66 kDa and the accession number is XP_028705775.1. | |||
TMPK-00380 |
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR4,TKF,FGFR4 β,FGF R4,FGFR... |
Human | HEK293 Cells |
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1. | |||
TMPK-00378 |
FGFR4 beta Protein, Human, Recombinant (His & Avi)
JTK2,CD334,FGFR4 β,FGF R4,TKF,FGFR-4,FGF |
Human | HEK293 Cells |
FGFR4 beta Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1. | |||
TMPY-03318 |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His)
tumor necrosis factor receptor superfamily, member 10d, deco... |
Rhesus | HEK293 Cells |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is XP_001107922.1. | |||
TMPY-03317 |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc)
tumor necrosis factor receptor superfamily, member 10d, deco... |
Rhesus | HEK293 Cells |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is XP_001107922.1. | |||
TMPK-00248 |
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)
DCR2,TNFRSF10D,RSF10D,CD264,TRUNDD,TRAILR4 |
Human | HEK293 Cells |
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 19.4 kDa and t... | |||
TMPK-00249 |
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated
TNFRSF10D,CD264,TRUNDD,DCR2,RSF10D,TRAILR4 |
Human | HEK293 Cells |
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is ... | |||
TMPY-02147 |
ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His)
ST2L,FIT-1,IL‑1 R4,interleukin 1 receptor-like 1,ST... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (isoform a, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.3 kDa and the accession number is Q01638-1. | |||
TMPJ-00849 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc)
Protein ST2,IL-1 R4,IL-33R,ST2V,suppression of tumo... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (V192A, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-110 KDa and the accession number is P14719-2. | |||
TMPY-02112 |
FGFR4 Protein, Human, Recombinant (His)
TKF,JTK2,CD334,fibroblast growth factor receptor 4 |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1. | |||
TMPY-02904 |
TLR4 Protein, Human, Recombinant (His)
TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284 |
Human | Baculovirus Insect Cells |
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed... | |||
TMPY-01087 |
FCGR4 Protein, Mouse, Recombinant (His)
Fcgr3a,FcgammaRIV,Fcrl3,Fc receptor, IgG, low affinity IV,48... |
Mouse | HEK293 Cells |
FCGR4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.4 kDa and the accession number is A0A0B4J1G0. | |||
TMPY-01719 |
DR4/TRAIL R1 Protein, Human, Recombinant (hFc)
TRAILR1,tumor necrosis factor receptor superfamily member 10... |
Human | HEK293 Cells |
DR4/TRAIL R1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is O00220. | |||
TMPY-05958 |
SARS-CoV-2 Spike RBD Protein (R408I, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike RBD Protein (R408I, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.5 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-00974 |
FGFR4 Protein, Mouse, Recombinant (His)
Fgfr-4,fibroblast growth factor receptor 4 |
Mouse | HEK293 Cells |
FGFR4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is A0A0R4IZY3. | |||
TMPK-00706 |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi)
DR4,MGC9365,TNFRSF10A,TRAIL-R,TRAIL R1,CD261,APO2 |
Human | HEK293 Cells |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220. | |||
TMPK-00449 |
HER4/ERBB4 Protein, Human, Recombinant (His & Avi), Biotinylated
E4ICD,ALS19,ErbB4,4ICD,HER4,p180erbB4,MGC138404 |
Human | HEK293 Cells |
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS. HER4/ERBB4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The... | |||
TMPH-00034 |
ASFV (isolate Tick/South Africa/Pretoriuskop Pr4/1996) p12 Protein (His)
Protein p12,Pret-110,Inner membrane protein p12 |
ASFV | E. coli |
Virus attachment protein. ASFV (isolate Tick/South Africa/Pretoriuskop Pr4/1996) p12 Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 12.7 kDa and the accession number is P0C9Y3. | |||
TMPY-03683 |
FGFR4 Protein, Rhesus, Recombinant (His)
fibroblast growth factor receptor 4 |
Rhesus | HEK293 Cells |
FGFR4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.8 kDa and the accession number is XP_001087243.1. | |||
TMPY-01348 |
CD200R4 Protein, Mouse, Recombinant (His)
Cd200r4,CD200 receptor 4,F630107N04Rik,MCD200RLa |
Mouse | HEK293 Cells |
CD200R4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is Q6XJV4. | |||
TMPK-00707 |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated
TNFRSF10A,CD261,DR4,APO2,TRAIL-R,MGC9365,TRAIL R1 |
Human | HEK293 Cells |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220. | |||
TMPJ-01255 |
CFHR4 Protein, Human, Recombinant (His)
CFHL4,Complement factor H-related protein 4,FHR-4,CFHR4<... |
Human | HEK293 Cells |
Complement factor H-related protein 4 is a protein that in humans is encoded by the CFHR4 gene. It is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains. CFHR4 is synthesized as a 578 amino acid precursor that contains an 19 amino acid signal peptide and a 569 amino acid mature chain. Human CFHR4 is involved in complement regulation. It can associate with lipoproteins a... | |||
TMPH-01065 |
CCR4 Protein-VLP, Human, Recombinant (His)
CC-CKR-4,CCR4,CCR-4,CD194,C-C chemokine receptor ty... |
Human | HEK293 Cells |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cel... | |||
TMPH-01797 |
NR4A2 Protein, Human, Recombinant (His)
NR4A2,Immediate-early response protein NOT,Nuclear ... |
Human | P. pastoris (Yeast) |
Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. NR4A2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 68.6 kDa and the accession number is P43354. | |||
TMPY-01404 |
CD200R4 Protein, Mouse, Recombinant (hFc)
CD200 receptor 4,F630107N04Rik,Cd200r4,MCD200RLa |
Mouse | HEK293 Cells |
CD200R4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is Q6XJV4. | |||
TMPY-02635 |
FGFR4 Protein, Rat, Recombinant (hFc)
fibroblast growth factor receptor 4 |
Rat | HEK293 Cells |
FGFR4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q498D6. | |||
TMPJ-00534 |
hFcgR4 Protein, Mouse, Recombinant (His)
Low Affinity Immunoglobulin γ Fc Region Receptor IV,FcgR... |
Mouse | HEK293 Cells |
Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of sensory perception of pain, wound healing etc. Three groups are included for Fc γ receptors (FcR), and they are Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). Among these, CD64 possess high affinity even for monomeric IgG, while CD32 and CD16 display a relative lower affinity ... | |||
TMPK-00585 |
FOLR4/Juno Protein, Human, Recombinant (His)
Folate receptor 4,FR-δ,Folbp3,FR-delta,Izumo1r,Juno,FR δ,FOL... |
Human | HEK293 Cells |
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno's presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor. FOLR4/Juno Pro... | |||
TMPK-00708 |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)
TRAIL R1,APO2,DR4,CD261,TRAIL-R,TNFRSF10A,MGC9365 |
Human | HEK293 Cells |
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations. | |||
TMPK-01171 |
FOLR4/Juno Protein, Mouse, Recombinant (His)
Juno,FOLR4, LOC390243,Folate receptor 4,FR δ,FR-del... |
Mouse | HEK293 Cells |
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno's presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor. FOLR4/Juno Pro... | |||
TMPY-06037 |
FGFR4 Protein, Human, Recombinant (His), Biotinylated
CD334,TKF,JTK2,fibroblast growth factor receptor 4 |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1. | |||
TMPY-02862 |
FGFR4 Protein, Rat, Recombinant (His)
fibroblast growth factor receptor 4 |
Rat | HEK293 Cells |
FGFR4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.3 kDa and the accession number is Q498D6. | |||
TMPY-03322 |
FGFR4 Protein, Rhesus, Recombinant (hFc)
fibroblast growth factor receptor 4 |
Rhesus | HEK293 Cells |
FGFR4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.6 kDa and the accession number is XP_001087243.1. | |||
TMPY-01987 |
FCGR4 Protein, Mouse, Recombinant (His & Avi), Biotinylated
FcgammaRIV,FcγRIV,4833442P21Rik,Fcgr3a,FcgRIV,Fcrl3,CD16-2,F... |
Mouse | HEK293 Cells |
FCGR4 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is A0A0B4J1G0. | |||
TMPH-01796 |
NR4A1 Protein, Human, Recombinant (His & Myc)
ST-59,NR4A1,Nuclear hormone receptor NUR/77,Orphan ... |
Human | E. coli |
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury. NR4A1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expre... | |||
TMPY-01720 |
DR4/TRAIL R1 Protein, Human, Recombinant (His)
APO2,tumor necrosis factor receptor superfamily member 10a,T... |
Human | HEK293 Cells |
DR4/TRAIL R1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O00220. | |||
TMPY-01977 |
FCGR4 Protein, Mouse, Recombinant (His & Avi)
Fcrl3,CD16-2,FcgammaRIV,FcγRIV,Fc receptor, IgG, low affinit... |
Mouse | HEK293 Cells |
FCGR4 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is A0A0B4J1G0. | |||
TMPY-01019 |
FGFR4 Protein, Mouse, Recombinant (His & hFc)
Fgfr-4,fibroblast growth factor receptor 4 |
Mouse | HEK293 Cells |
FGFR4 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67 kDa and the accession number is A0A0R4IZY3. | |||
TMPY-00806 |
FGFR4 Protein, Human, Recombinant (hFc)
fibroblast growth factor receptor 4,CD334,TKF,JTK2 |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is P22455-1. | |||
TMPY-06553 |
CXCR4 Protein, Human, Recombinant
NPYY3R,chemokine (C-X-C motif) receptor 4,D2S201E,HM89,NPYRL... |
Human | HEK293 Cells |
CXCR4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 39.75 kDa and the accession number is P61073-1. | |||
TMPK-00448 |
HER4/ERBB4 Protein, Human, Recombinant (His & Avi)
HER4,ALS19,4ICD,p180erbB4,MGC138404,E4ICD,ErbB4 |
Human | HEK293 Cells |
Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS. HER4/ERBB4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted mol... | |||
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