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Search Results for " r-isomer "
Targets Recommended: Others

67

抑制剂 & 化合物

3

天然产物

1

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T26744 BAY-598 R-isomer

BAY598 R-isomer,BAY 598 R-isomer

Others Others
BAY-598 R-异构体是BAY589的R-异构体,它可用作参考化合物。它是是赖氨酸N-甲基转移酶(SMYD2)的抑制剂,对SMYD2比蛋白酶激活的受体1(PAR1)具有选择性。
T12617 (R)-CR8 trihydrochloride

CR8, (R)-Isomer trihydrochloride

Apoptosis; CDK Apoptosis; Cell Cycle/Checkpoint
(R)-CR8 trihydrochloride (CR8, (R)-Isomer trihydrochloride) 是一种 CDK1/2/5/7/9 抑制剂,可作为分子胶降解剂,具有神经保护活性,可诱导细胞凋亡。
T11650 INCB3344 R-isomer

Others Others
INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.
T63166L (S, R)-LSN 3318839

(S, R)-LSN 3318839(Isomer-2764704-18-7)

Glucagon Receptor GPCR/G Protein
T70544 MKC-963 (R-isomer)

Others Others
MKC-963 is a platelet aggregation inhibitor and autoinducer of CYP3A4.
T12617L (R)​-​CR8

(R)-CR8,(R)-Isomer,(2R)-2-[[9-异丙基-6-[[[4-(2-吡啶基)苯基]甲基]氨基]-9H-嘌呤-2-基]氨基]-1-丁醇,CR8

Apoptosis; CDK Apoptosis; Cell Cycle/Checkpoint
(R)​-​CR8 ((R)-Isomer) 是 Roscovitine 类似物,是CDK1/2/5/7/9抑制剂。它作为一种分子胶降解剂来消耗细胞周期蛋白 K。它诱导细胞凋亡并具有神经保护作用。
T71236 Oxybutynin R-isomer HCl

Others Others
Oxybutynin R-isomer , also known as Aroxybutynin, is a muscarinic receptor antagonist. Aroxybutynin is the optically avtice inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Oxybutynin exerts direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. It exhibits one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. No blo...
T6183 ISRIB (trans-isomer)

ISRIB,ISRIB trans-isomer,trans-isomer,trans-ISRIB

Apoptosis; PERK; Autophagy Apoptosis; Autophagy
ISRIB (trans-isomer) (ISRIB trans-isomer)是一种 PERK 的高效抑制剂,可有效逆转 eIF2α 磷酸化的作用,IC50值为 5 nM。
T33384 Midodrine (R-isomer HCl)

ProAmatine,Midodrine,ST-1085,Gutron,Amatine

Others Others
Midodrine is a vasopressor/antihypertensive agent for the treatment of symptomatic postural hypotension.
T69703 BAY-6035-R-isomer

Others Others
BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.
TD0058 6-TRITC

四甲基罗丹明-6-异硫氰酸(单一化合物),R isomer [Tetramethylrhodamine-6-isothiocyanate]

6-TRITC can bind to various antibody proteins, and the antibody does not lose its specificity of binding to certain antigens, and has a strong yellow-green fluorescence in alkaline solution.
T5517 (R)-Carisbamate

Others Others
(R)-Carisbamate 是 Carisbamate 的 R-异构体。 Carisbamate 是一种实验性抗惊厥药。
T26914L (R)-AZD 9639

Others Others
(R)-AZD 9639 是 AZD 9639 的 R型异构体。AZD 9639 是一种新型呼吸道合胞病毒(RSV)融合抑制剂,具有抗病毒活性。
T22413 (R)-Viloxazine Hydrochloride

Others; Reductase Endocrinology/Hormones; Metabolism; Others
(R)-Viloxazine Hydrochloride是Viloxazine的R型异构体,Viloxazine是一种选择性去甲肾上腺素再摄取抑制剂(NRI),可用作抗抑郁药。
T50052 1,2-diphenylpropan-2-amine

Others Others
1,2-diphenylpropan-2-amine 是Remacemide 的(S,R)-异构体单盐酸盐代谢产物。1,2-diphenylpropan-2-amine 具有抗惊厥作用。
T1021 (R)-Lansoprazole

Dexlansoprazole,右旋兰索拉唑,T 168390,TAK 390,R-(+)-Lansoprazole

Proton pump Membrane transporter/Ion channel
(R)-Lansoprazole (T 168390) 是Lansoprazole 的R 型异构体。Lansoprazole 是口服有效的质子泵抑制剂,能抑制胃酸生成。Lansoprazole 是中性鞘磷脂酶(N-SMase)的抑制剂(外泌体抑制剂),能透过血脑屏障。
T72754L (R)-JAK2/STAT3-IN-10a

Antiviral Immunology/Inflammation
(R)-JAK2/STAT3-IN-10a 是 JAK2/STAT3-IN-1 的R型异构体。JAK2/STAT3-IN-1 是一种 GP130 D1 结构域抑制剂,具有抗肿瘤活性,抑制 JAK2 和 STAT3 磷酸化。(R)-JAK2/STAT3-IN-1 对 GP130 蛋白的 KD 值为3.8μM。
T68002L (R)-Naroparcil

Others Others
(R)-Naroparcil 是 Naroparcil 的异构体。 Naroparcil 是一种4-甲基伞形酮基 β-D-木糖苷类似物,与血管平滑肌细胞增殖有关,在 Wessler 淤滞模型中抑制血栓的形成。
T63898 Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-

PPAR DNA Damage/DNA Repair; Metabolism
Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-是一种PPARα/γ双激动剂,EC50 分别为 0.358μM 和1.21μM。Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-是AleglitazarR 型异构体。
T29905 Alprenolol tartrate, (R)-

Others Others
Alprenolol tartrate, (R)-, is the R isomer of Alprenolol tartrate.
T12611 R 80123

Others Others
R 80123 is a highly selective inhibitor of phosphodiesterase,is the Z-isomer of R 79595
T13442 (R)-BAY1238097

Others Others
(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a selective BET inhibitor.
T21265 (R)-Amlodipine

D-Amlodipine,(R)-(+)-Amlodipine,(+)-Amlodipine

Others Others
(R)-Amlodipine is the R isomer of Amlodipine, a medication used to prevent chest pain and lower blood pressure.
T17307 (R)-Ofloxacin

DR3354,D-Ofloxacin,DR-3354,DR 3354,(R)-氧氟沙星,(R)-(+)-Ofloxacin,(+)-Ofloxacin

Others Others
(R)-Ofloxacin is a R-isomer of Ofloxacin, an antibiotic used to treat a number of bacterial infections.
T70780 BW 737C89

Others Others
BW 737C89 is a highly potent dopamine D1 receptor antagonist; BW-737C is the (S)-isomer; BW-736C is the (R)-isomer.
T12621 (R)-FT671

Others Others
(R)-FT671 is the R-isomer of FT671. FT671 is a potent, non-covalent and selective inhibitor of USP7 (IC50 of 52 nM)
T29671 Adrafinil, (R)-

UNII-Z61JQF40LJ,Adrafinil (R)-,R-(+)-Adrafinil

Others Others
Adrafinil, (R)- is the R isomer of Adrafinil -- a eugeroic that was formerly used to promote alertness, attention, wakefulness, mood, and other parameters, particularly in the elderly.
T31176 Dabelotine, (R)-

UNII-3NZJ1HNE7Y

Others Others
Dabelotine, (R)- 是 Dabelotine 的 R 型异构体。Dabelotine 是一种肾上腺素能受体激动剂,可用于研究痴呆症。
T84578 15(R)-15-methyl Prostaglandin F2α

15(R)-15-methyl PGF2α

Others Others
15(R)-15-methyl PGF2α, a metabolically stable analog of PGF2α, is an inactive, prodrug PGF agonist intended for activation by gastric acid through oral administration. This transformation involves acid-catalyzed epimerization that converts 15(R)-15-methyl PGF2α into its active counterpart, the 15(S)-isomer. Upon conversion, the 15(S)-isomer has been shown to induce luteolysis in rhesus monkeys following an approximately 12 mg/animal dosage, a response not observed with the 15(R)-isomer.
T26266 TH-162

L-PIA,(R)​-PIA,(R)​- PIA,(R)​-​PIA,L-2-N6-(Phenylisopropyl)adenosine

Others Others
TH-162, also known as (R)​-​PIA and Adenosine, N-(1-methyl-2-phenylethyl)-, (R)-, is an agonist of the A1 adenosine receptor. Affinity for adenosine receptors is approx. 100× that of the (+)-isomer.
T21234 (R)-Dihydrolipoic acid

Others Others
(R)-Dihydrolipoic acid is a R-isomer of Dihydrolipoic acid. It is optically active, but only the R-enantiomer is biochemically significant. The lipoic acid/dihydrolipoic acid pair participate in a variety of biochemical transformations.
T37227 (±)8(9)-DiHET

Others Others
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. The 8(S),9(R)-EET isomer is metabolized by platelet COX to form 8(S),9(R),11(R)-THETA, a trihydroxy fatty acid which may act as a renal vasoconstrictor.
T17951 Fmoc-Gly-Gly-D-Phe-OtBu

Others; ADC Linker Antibody-drug Conjugate/ADC Related; Others
Fmoc-Gly-Gly-D-Phe-OtBu, an ADC cleavable linker, is utilized in the synthesis of antibody-drug conjugates. It is the R-isomer of Fmoc-Gly-Gly-Phe-OtBu [1].
T72820 (R)-Casopitant

(R)-GW679769

Others Others
(R)-Casopitant ((R)-GW679769) 是Casopitant 的异构体。Casopitant 是一种 NK(1)-受体拮抗剂。Casopitant 可用于化疗引起的恶心和呕吐的研究。
T61309 (R)-Oxybutynin

Others Others
(R)-Oxybutynin (Aroxybutynin) is an orally active muscarinic receptor antagonist, which exhibits antimuscarinic, antispasmodic, and anticholinergic activity. This compound, being the (R)-isomer of Oxybutynin, competitively antagonizes Carbachol-induced contractions. It is particularly useful in researching neurogenic bladder dysfunction-related incontinence [1] [2] [3].
T72913 (R)-MLN-4760

Others Others
(R)-MLN-4760 是 MLN-4760 的活性较低的 R 型异构体,是一种ACE2抑制剂,IC50值为 8.4 μM。
T36840 (R)-Omeprazole (sodium salt)

Others Others
(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).
T38031 (R)-KT109

(R)-KT109

Others Others
(R)-KT109 is the (R) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (R)-KT109 is an inhibitor of DAGLβ (IC50 = 0.79 nM) and of DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol . It also inhibits α/β-hydrolase domain-containing protein 6 (ABHD6) with an IC50 value of 2.51 nM. (R)-KT109 is more potent at DAGLβ, DAGLα, and ABHD6 than (S)-KT109 .
T84559 15(S)-Fluprostenol

Others Others
15(S)-Fluprostenol, an isomer of the FP receptor agonist fluprostenol, serves as a potential active metabolite of 15(S)-fluprostenol isopropyl ester. It can function as an agonist at FP receptors, though with lower potency compared to its 15(R) epimer, fluprostenol.
T84624 8-iso-15(R)-Prostaglandin F2α

8-iso-15-epi PGF2α

Others Others
8-iso-15(R)-Prostaglandin F2α (8-iso-15(R) PGF2α) is a chemically distinct member within a broad group of prostaglandin-like eicosanoids, produced through the free radical peroxidation of arachidonic acid contained in membrane phospholipids. It represents the C-15 epimer of 8-isoPGF2α, distinguished as the sole isoprostane isomer extensively examined across numerous biological systems.
T62881 (R)-BAY-899

Others Others
(R)-BAY-899 是一种 BAY-899 的 R 型异构体。其中 BAY-899 是一种选择性的、口服具有活力的促黄体生成激素受体 (LH-R) 拮抗剂,作用于 hLH (人 LH) (IC50: 185 nM) 和 rLH (大鼠 LH) (IC50: 46 nM)。
T35467 (±)18-HETE

Others Others
(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, whereas 18(S)-HETE does not affect perfusion pressure. 18-HETE has negligible effects on ATPase activity. 18(R)-HETE at 1 μM completely blocks 20-HETE-induced vasoconstriction of renal arterioles.
T71736 AMG-628, (R)-

Others Others
AMG-628, (R)- is the R isomer of AMG-628 --- a potent, ATP-competitive inhibitor of Raf kinases. AMG-628 displays selectivity for Raf kinases and inhibits activation of tyrosine protein kinases such as VEGFR2, Lyn, Flt1 and Fms. AMG-628 has shown to inhibit growth, and induces cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation.
T70430 XK469

Others Others
XK489 is a synthetic quinoxaline phenoxypropionic acid derivative with proapoptotic and antiproliferative activities. R(+)XK469 selectively inhibits topoisomerase II-beta, blocks activation of MEK/MAPK signaling kinases, stimulates caspases, and upregulates p53-dependent proteins, including cyclins A and B1, thereby arresting cancer cells in the G2/M phase of the cell cycle. Both R(+) and S(-) isomers of this agent are cytotoxic, although the R-isomer is more potent.
T73507 NS1219

(R)-SPD502

Others Others
NS1219 ((R)-SPD502) 是 NS 1209 的异构体。NS1209 是一种选择性AMPA 受体拮抗剂,具有神经保护活性。NS1209 可用于中风、神经性疼痛和癫痫的研究。
T72663 (Rac)-Etavopivat

(Rac)-FT-4202

Others Others
(Rac)-Etavopivat((Rac)-FT-4202) 是Etavopivat 异构体。Etavopivat 是一种具有口服活性的的红细胞丙酮酸激酶-R (PKR) 激活剂,可以用于镰状细胞病和其他血红蛋白疾病研究。
T38148 (S)-KT109

(S)-KT109

Others Others
(S)-KT109 is the (S) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (S)-KT109 is a less potent inhibitor of DAGLβ (IC50 = 39.81 nM), DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (IC50 = 794.3 nM), and α/β-hydrolase domain-containing protein 6 (ABHD6; IC50 = 630.9 nM) than (R)-KT109 .
T36608 (±)8-HEPE

Others Others
(±)8-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 8(S)-HEPE and 8(R)-HEPE. The ability of (±)8-HEPE to induce hatching of E. modestus and B. balanoides eggs is probably due to the presence of the 8(R) isomer within the racemic mixture.[1][2] Reference:[1]. Shing, T.K.M., Gibson, K.H., Wiley, J.R., et al. First total synthesis of a barnacle hatching factor 8(R)-hydroxy-eicosa-5(Z),9(E),11(Z)-pentaenoic acid. Tetrahedron Letters 35, 1067-1070 (1994).[2]. Hill, E...
T71483 Streptonigrin (racemate)

Others Others
Streptonigrin is an aminoquinone antitumor and antibacterial antibiotic produced by Streptomyces flocculus. Streptonigrin inhibits β-Catenin/Tcf signaling and shows cytotoxicity in β-catenin-activated cells. Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells. Note: Streptonigrin from natural resource is (-)-rotation, has CAS#3930-19-6 and is a R-isomer.
T84598 15(R),19(R)-hydroxy Prostaglandin F2α

15(R),19(R)-hydroxy PGF2α

Others Others
19(R)-Hydroxylated prostaglandins (PGs) are present at µg/ml concentrations in the semen of some mammalian species, notably primates, with the majority being from the PGE series and featuring a 15(S),19(R) hydroxyl stereochemistry. These compounds are also observed in marsupials' seminal plasma, where F-type 1 and 2-series compounds are predominant. The 15(R)-hydroxy epimer represents the inverse or "unnatural" isomer at C-15 for these 19-hydroxylated PGs. Although the biological function of 19(...

化合物

BAY-598 R-isomer
Cat.No: T26744
Synonym: BAY598 R-isomer,BAY 598 R-isomer
Target: Others
(R)-CR8 trihydrochloride
Cat.No: T12617
Synonym: CR8, (R)-Isomer trihydrochloride
Target: Apoptosis, CDK
INCB3344 R-isomer
Cat.No: T11650
Synonym:
Target: Others
(S, R)-LSN 3318839
Cat.No: T63166L
Synonym: (S, R)-LSN 3318839(Isomer-2764704-18-7)
Target: Glucagon Receptor
MKC-963 (R-isomer)
Cat.No: T70544
Synonym:
Target: Others
(R)​-​CR8
Cat.No: T12617L
Synonym: (R)-CR8,(R)-Isomer,(2R)-2-[[9-异丙基-6-[[[4-(2-吡啶基)苯基]甲基]氨基]-9H-嘌呤-2-基]氨基]-1-丁醇,CR8
Target: Apoptosis, CDK
Oxybutynin R-isomer HCl
Cat.No: T71236
Synonym:
Target: Others
ISRIB (trans-isomer)
Cat.No: T6183
Synonym: ISRIB,ISRIB trans-isomer,trans-isomer,trans-ISRIB
Target: Apoptosis, PERK, Autophagy
Midodrine (R-isomer HCl)
Cat.No: T33384
Synonym: ProAmatine,Midodrine,ST-1085,Gutron,Amatine
Target: Others
BAY-6035-R-isomer
Cat.No: T69703
Synonym:
Target: Others
6-TRITC
Cat.No: TD0058
Synonym: 四甲基罗丹明-6-异硫氰酸(单一化合物),R isomer [Tetramethylrhodamine-6-isothiocyanate]
Target:
(R)-Carisbamate
Cat.No: T5517
Synonym:
Target: Others
(R)-AZD 9639
Cat.No: T26914L
Synonym:
Target: Others
(R)-Viloxazine Hydrochloride
Cat.No: T22413
Synonym:
Target: Others, Reductase
1,2-diphenylpropan-2-amine
Cat.No: T50052
Synonym:
Target: Others
(R)-Lansoprazole
Cat.No: T1021
Synonym: Dexlansoprazole,右旋兰索拉唑,T 168390,TAK 390,R-(+)-Lansoprazole
Target: Proton pump
(R)-JAK2/STAT3-IN-10a
Cat.No: T72754L
Synonym:
Target: Antiviral
(R)-Naroparcil
Cat.No: T68002L
Synonym:
Target: Others
Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
Cat.No: T63898
Synonym:
Target: PPAR
Alprenolol tartrate, (R)-
Cat.No: T29905
Synonym:
Target: Others
R 80123
Cat.No: T12611
Synonym:
Target: Others
(R)-BAY1238097
Cat.No: T13442
Synonym:
Target: Others
(R)-Amlodipine
Cat.No: T21265
Synonym: D-Amlodipine,(R)-(+)-Amlodipine,(+)-Amlodipine
Target: Others
(R)-Ofloxacin
Cat.No: T17307
Synonym: DR3354,D-Ofloxacin,DR-3354,DR 3354,(R)-氧氟沙星,(R)-(+)-Ofloxacin,(+)-Ofloxacin
Target: Others
BW 737C89
Cat.No: T70780
Synonym:
Target: Others
(R)-FT671
Cat.No: T12621
Synonym:
Target: Others
Adrafinil, (R)-
Cat.No: T29671
Synonym: UNII-Z61JQF40LJ,Adrafinil (R)-,R-(+)-Adrafinil
Target: Others
Dabelotine, (R)-
Cat.No: T31176
Synonym: UNII-3NZJ1HNE7Y
Target: Others
15(R)-15-methyl Prostaglandin F2α
Cat.No: T84578
Synonym: 15(R)-15-methyl PGF2α
Target: Others
TH-162
Cat.No: T26266
Synonym: L-PIA,(R)​-PIA,(R)​- PIA,(R)​-​PIA,L-2-N6-(Phenylisopropyl)adenosine
Target: Others
(R)-Dihydrolipoic acid
Cat.No: T21234
Synonym:
Target: Others
(±)8(9)-DiHET
Cat.No: T37227
Synonym:
Target: Others
Fmoc-Gly-Gly-D-Phe-OtBu
Cat.No: T17951
Synonym:
Target: Others, ADC Linker
(R)-Casopitant
Cat.No: T72820
Synonym: (R)-GW679769
Target: Others
(R)-Oxybutynin
Cat.No: T61309
Synonym:
Target: Others
(R)-MLN-4760
Cat.No: T72913
Synonym:
Target: Others
(R)-Omeprazole (sodium salt)
Cat.No: T36840
Synonym:
Target: Others
(R)-KT109
Cat.No: T38031
Synonym: (R)-KT109
Target: Others
15(S)-Fluprostenol
Cat.No: T84559
Synonym:
Target: Others
8-iso-15(R)-Prostaglandin F2α
Cat.No: T84624
Synonym: 8-iso-15-epi PGF2α
Target: Others
(R)-BAY-899
Cat.No: T62881
Synonym:
Target: Others
(±)18-HETE
Cat.No: T35467
Synonym:
Target: Others
AMG-628, (R)-
Cat.No: T71736
Synonym:
Target: Others
XK469
Cat.No: T70430
Synonym:
Target: Others
NS1219
Cat.No: T73507
Synonym: (R)-SPD502
Target: Others
(Rac)-Etavopivat
Cat.No: T72663
Synonym: (Rac)-FT-4202
Target: Others
(S)-KT109
Cat.No: T38148
Synonym: (S)-KT109
Target: Others
(±)8-HEPE
Cat.No: T36608
Synonym:
Target: Others
Streptonigrin (racemate)
Cat.No: T71483
Synonym:
Target: Others
15(R),19(R)-hydroxy Prostaglandin F2α
Cat.No: T84598
Synonym: 15(R),19(R)-hydroxy PGF2α
Target: Others
Cat. No. Product Name Target Signaling Pathways
T5302 (R)-pyrrolidine-2-carboxylic acid

D-脯氨酸,D-Proline

Others; Endogenous Metabolite Metabolism; Others
(R)-pyrrolidine-2-carboxylic acid (D-Proline) 是天然氨基酸 L -脯氨酸的异构体。D -氨基酸在人类血浆和唾液中含量相对较高。这些氨基酸可能是细菌来源,但也有证据表明它们是通过氨基酸消旋酶活性内源性产生的。
TN7295 (R)-(+)-Tetrahydroberberine

(R)-(+)-Canadine,(+)-Canadine

Others Others
(R)-(+)-Tetrahydroberberine 为 (S)-(-)-Tetrahydroberberine 的非活性异构体,常用作实验对照物。其中,(S)-(-)-Tetrahydroberberine 是生物碱种类,作为小檗碱生物合成路径中的中间体,具备杀虫作用。
T74193 (R)-IDHP

Others Others
(R)-IDHP为IDHP异构体,属于丹参代谢物。该化合物能通过抑制血管平滑肌细胞电压依赖性钙通道与受体操作钙通道的Ca2+释放和Ca2+内流,发挥血管松弛作用,适用于心脑血管疾病研究。

天然产物

(R)-pyrrolidine-2-carboxylic acid
Cat.No: T5302
Synonym: D-脯氨酸,D-Proline
Target: Others, Endogenous Metabolite
(R)-(+)-Tetrahydroberberine
Cat.No: TN7295
Synonym: (R)-(+)-Canadine,(+)-Canadine
Target: Others
(R)-IDHP
Cat.No: T74193
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TMIH-0187 Dexlansoprazole-d4

(R)-Lansoprazole-d4

Dexlansoprazole-d4 是 Dexlansoprazole 的氘代化合物。Dexlansoprazole 的 CAS 号为 138530-94-6。(R)-Lansoprazole 是Lansoprazole 的R型异构体。Lansoprazole 是口服有效的质子泵抑制剂,能抑制胃酸生成。Lansoprazole 是中性鞘磷脂酶(N-SMase)的抑制剂(外泌体抑制剂),能透过血脑屏障。

同位素标记化合物

Dexlansoprazole-d4
Cat.No: TMIH-0187
Synonym: (R)-Lansoprazole-d4
Target:
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