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Search Results for " r 450 "
Targets Recommended: Others

2

抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T10952L Dabuzalgron HCl

R1240,R-450,R450,RO-1151240,R-1240,RO1151240

Others Others
Dabuzalgron, an adrenoceptor agonist, is used potentially for the treatment of urinary incontinence.
T35458 (R)-nitro-Blebbistatin

Others Others
(R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin , which is the inactive form of (-)-blebbistatin . Prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (R)-nitro-Blebbistatin has the same stereoche...

化合物

Dabuzalgron HCl
Cat.No: T10952L
Synonym: R1240,R-450,R450,RO-1151240,R-1240,RO1151240
Target: Others
(R)-nitro-Blebbistatin
Cat.No: T35458
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T1011 Itraconazole

伊曲康唑,R51211

P450; Hedgehog/Smoothened; Antibiotic; Autophagy; Antifungal Autophagy; GPCR/G Protein; Metabolism; Microbiology/Virology; Stem Cells
Itraconazole (R51211) 属于三唑类天然产物,是一种抗真菌剂,具有口服活性。Itraconazole 是一种 Hedgehog 信号通路拮抗剂,一种 oxysterol-binding protein (OSBP) 抑制剂,也是一种细胞色素 P-450 依赖性酶的抑制剂。

天然产物

Itraconazole
Cat.No: T1011
Synonym: 伊曲康唑,R51211
Target: P450, Hedgehog/Smoothened, Antibiotic, Autophagy, Antifungal
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