268
46
1
90
11
Cat. No. | Product Name | ||
---|---|---|---|
DO1200 | 药物靶点库 | 53200 compounds | |
数量多,含53200种小分子化合物,是高通量筛选的有力工具; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9281 |
(S)-2-((R)-3-(4-chlorophenyl)-N’-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-methylbutanamide
|
Others | Others |
(S)-2-((R)-3-(4-chlorophenyl)-N’-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-methylbutanamide 是一种大麻素受体拮抗剂/反向激动剂。 | |||
T23217 |
(R)-4-Carboxyphenylglycine
|
Others | Others |
(R)-4-Carboxyphenylglycine is a NMDA receptor antagonist. | |||
TQ0162 |
R-1479
4'-Azidocytidine |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
R-1479 (4'-Azidocytidine) 是一种 RdRp 抑制剂,对于 HCV 亚基因组复制子系统中的 HCV RNA 复制,IC50 值为 1.28 μM。 | |||
T12634 |
(R)-NVS-ZP7-4
|
Others | Others |
(R)-NVS-ZP7-4 是 NVS-ZP7-4 的 R 型异构体。 NVS-ZP7-4 是一个报道用于探测内质网锌水平影响的化学分子,是一种锌转运体 SLC39A7(ZIP7)的抑制剂,并研究 ZIP7 作为 Notch 通路中的一种新的可成药节点。 | |||
T37265 |
15(R)-Lipoxin A4
15(R)-Lipoxin A4,AT-Lipoxin A4 |
Others | Others |
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspirin-triggered formation of 15(R)-HETE from arachidonic acid. [1] [2] 15(R)-LXA4 inhibits LTB4-induced chemotaxis, adherence, and transmigration of neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.[2] [3] The anti-inflammatory effects of aspirin may... | |||
T14900 |
CCR2-RA-[R]
(5R)-4-乙酰基-1-(4-氯-2-氟苯基)-5-环己基-1,5-二氢-3-羟基-2H-吡咯-2-酮 |
CCR | Immunology/Inflammation; Microbiology/Virology |
CCR2-RA-[R] 是一种 C-C 趋化因子受体 2 型 (CCR2) 变构拮抗剂,IC50值为103 nM。 | |||
T23216 |
(R)-3C4HPG
|
Others | Others |
NMDA and AMPA/kainate receptor antagonist | |||
T85200 |
17(R)-Resolvin D4
4(S),5(R),17(R)-trihydroxy-DHA,17(R)-RvD4 |
Others | Others |
17(R)-Resolvin D4 (17(R)-RvD4) is an epimer of RvD4, generated through the aspirin-induced modification process. | |||
T67699L |
ALK/ROS1 inhibitor 2e HCL
(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base) |
Apoptosis | Apoptosis |
ALK/ROS1 inhibitor 2e HCL 具有抗凋亡、抗增殖和抗肿瘤活性。 | |||
T12617L |
(R)-CR8
(R)-CR8,(R)-Isomer,(2R)-2-[[9-异丙基-6-[[[4-(2-吡啶基)苯基]甲基]氨基]-9H-嘌呤-2-基]氨基]-1-丁醇,CR8 |
Apoptosis; CDK | Apoptosis; Cell Cycle/Checkpoint |
(R)-CR8 ((R)-Isomer) 是 Roscovitine 类似物,是CDK1/2/5/7/9抑制剂。它作为一种分子胶降解剂来消耗细胞周期蛋白 K。它诱导细胞凋亡并具有神经保护作用。 | |||
T19618 |
(R)-(-)-JQ1 Enantiomer
(R)-(-)2-(4-(4-氯苯基)-2,3,9-三甲基-6H-噻吩并[3,2-F][1,2,4]三唑并[4,3-A][1,4]二氮杂环庚烷-6-基)乙酸叔丁酯 |
Epigenetic Reader Domain | Chromatin/Epigenetic |
(R)-(-)-JQ1 Enantiomer 是 (+)-JQ1 的立体异构体。 (+)-JQ1 是一种 BET 溴结构域抑制剂,对BRD4(1/2)的IC50 为 77 和 33 nM。 | |||
T26889 |
Borofalan(10B)
L-4-Boronophenylalanine,4-10硼酸-L-苯丙氨酸 |
Others | Others |
Borofalan(10B) (L-4-Boronophenylalanine) 具有抗肿瘤作用,可用于研究复发性或局部晚期头颈癌。 | |||
T15707 |
Laninamivir
(4S,5R,6R)-5-乙酰氨基-4-胍基-6-((1R,2R)-2,3-二羟基-1-甲氧基丙基)-5,6-二氢-4H-吡喃-2-甲酸,R 125489 |
Influenza Virus | Microbiology/Virology |
Laninamivir (R 125489) 是一种流感神经氨酸酶抑制剂,对流感病毒 H12N5 NA (N5),pH1N1 N1 NA (p09N1) 和 A/RI/5+/1957 H2N2 N2 (p57N2) 的 IC50值分别为 0.90 nM、1.83 nM 和 3.12 nM。 | |||
T17921 |
(S,R,S)-AHPC-PEG4-N3
VH032-PEG4-N3,VHL Ligand-Linker Conjugates 5,E3 ligase Ligand-Linker Conjugates 4 |
Others; PROTAC Linker | Others; PROTAC |
(S,R,S)-AHPC-PEG4-N3 (VHL Ligand-Linker Conjugates 5) is a synthesized conjugate that functions as a ligand-linker in E3 ligase-based systems. It is composed of the (S,R,S)-AHPC VHL ligand and a 4-unit PEG linker, both commonly employed in PROTAC technology. | |||
T15190L |
(S,R,S)-AHPC-PEG4-NH2
VHL Ligand-Linker Conjugates 4,E3 ligase Ligand-Linker Conjugates 7 Free Base,VH032-PEG4-NH2 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) 是一种合成的 E3 连接酶配体-接头偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 4 单元 PEG 接头。 | |||
T67699 |
(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide
|
Others | Others |
(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67699,CAS号为 2365497-12-5。 | |||
T78825 |
D4R agonist-1
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
D4R agonist-1 是一种具有选择性和有效性的 D4R 部分激动剂(Ki:2.2 nM)。D4R agonist-1 可用于研究神经系统疾病。 | |||
T10293 |
AM095 free acid
[4'-[3-甲基-4-[[[((R)-1-苯基乙基)氧基]羰基]氨基]异恶唑-5-基]联苯-4-基]乙酸 |
LPA Receptor; LPL Receptor | GPCR/G Protein |
AM095 free acid 是LPA1受体拮抗剂,对重组人和小鼠 LPA1 的IC50值分别为 0.98 和 0.73 μM。 | |||
T33519 |
MTOB
α-keto-γ-Methylthiobutyric acid,4-甲硫基-2-氧丁酸钠,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid |
Others | Others |
MTOB (α-keto-γ-Methylthiobutyric acid) 是 c 末端结合蛋白 (CtBP) 的底物,可干扰 CtBP 在细胞培养物和小鼠中的致癌活性。它还积极调节 TCF-4 信号传导,导致癌症干细胞 (CSC) 生长和自我更新。 | |||
T18640 |
(S,R,S)-AHPC-C4-NH2 hydrochloride
VH032-C4-NH2 hydrochloride,E3 ligase Ligand-Linker Conjugates 28,VHL Ligand-Linker Conjugates 13 |
Others; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-C4-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 28) 是一种合成的 E3 连接酶配体- linker 偶联物,包含基于 (S,R,S)-AHPC 的 VHL 配体和 linker。 | |||
T19335 |
Danegaptide Hydrochloride
GAP-134 (Hydrochloride),ZP 1609 Hydrochloride,(4R)-甘氨酰基-4-(苯甲酰基氨基)-L-脯氨酸盐酸盐 |
Gap Junction Protein | Cytoskeletal Signaling |
Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) 是一种具有口服活性的间隙连接蛋白选择性修饰剂,具有抗心律不齐的作用。 | |||
T5415 |
γ-GT
H-GLA(PNA)-OH,L-谷氨酸 5-(3-甲酸-4硝基苯胺)铵盐 |
Others | Others |
γ-GT (H-GLA(PNA)-OH) 是一种 γ-谷氨酰转移酶(glutamyl transferase)的底物。 | |||
T70814 |
Alnespirone
|
Others | Others |
Alnespirone, also known as S-20499, is a selective 5-HT1A receptor full agonist of the azapirone chemical class. It has both antidepressant and anxiolytic effects. | |||
T11361 | γ-Secretase modulator 4 | Others | Others |
γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.017 μM and 0.014 μM in mouse and human, respectively. | |||
T14045 |
Leukotriene B4
LTB4,5(S),12(R)-DiHETE |
Others | Others |
Leukotriene B4 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | |||
T67112 |
(R)-5,7-Difluorochroman-4-ol
|
Others | Others |
(R)-5,7-Difluorochroman-4-ol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67112,CAS号为 1270294-05-7。 | |||
T63089 |
(R)-IL-17 modulator 4
|
Others | Others |
(R)-IL-17 modulator 4 是 IL-17 modulator 4 的 R 构型形式,是 IL-17 modulator 1 的前药。其中 IL-IL-17 modulator 1 是一种高效的、口服具有活力的 IL-17 调节剂。 | |||
T124872 |
4,R-ajmalicine N-oxide
|
Others | Others |
4,R-ajmalicine N-oxide 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124872。 | |||
T66671 |
(R)-3-Amino-4-(benzyloxy)-4-oxobutanoic acid
|
||
(R)-3-Amino-4-(benzyloxy)-4-oxobutanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66671,CAS号为 79337-40-9。 | |||
T67059 |
(R)-1-(4-Nitrophenyl)ethanamine hydrochloride
|
Others | Others |
(R)-1-(4-Nitrophenyl)ethanamine hydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67059,CAS号为 57233-86-0。 | |||
T66871 |
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate
|
Others | Others |
Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66871,CAS号为 141942-85-0。 | |||
T19645 |
PNU-100440
(5R)-3-[3-氟-4-(4-吗啡啉基)苯基]-5-羟甲基-2-恶唑烷酮 |
Others | Others |
PNU-100440 是一种生物活性化合物。它是合成利奈唑胺二聚物的中间体,利奈唑胺二聚物是抗菌剂利奈唑胺的杂质。 | |||
T18666 |
(S,R,S)-AHPC-C4-NH2
VH032-C4-NH2 |
Others | Others |
(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate of an E3 ligase ligand-linker, which combines the VHL ligand based on (S,R,S)-AHPC and a linker specifically designed for EED-Targeted PROTAC[1]. | |||
T65787 |
(R)-3-Amino-4-hydroxybutanoic acid
|
||
(R)-3-Amino-4-hydroxybutanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65787,CAS号为 16504-56-6。 | |||
T85014 |
(R)-4-Amino-3-hydroxybutyric Acid
L-γ-Amino-β-hydroxybutyric Acid |
Others | Others |
(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizure... | |||
T65902 |
(R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate
|
Others | Others |
(R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65902,CAS号为 219823-47-9。 | |||
T67182 |
(R)-4-Propyldihydrofuran-2(3H)-one
|
Others | Others |
(R)-4-Propyldihydrofuran-2(3H)-one 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67182,CAS号为 63095-51-2。 | |||
T67274 |
(R)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(R)-1-phenylethoxy]phthalazine
|
Others | Others |
(R)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(R)-1-phenylethoxy]phthalazine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67274。 | |||
T66101 |
(R)-2-Aminopent-4-enoic acid hydrochloride
|
Others | Others |
(R)-2-Aminopent-4-enoic acid hydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66101,CAS号为 108412-04-0。 | |||
T65025 |
(R)-Boc-4-methoxy-β-Phe-OH
|
Others | Others |
(R)-Boc-4-methoxy-β-Phe-OH 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65025,CAS号为 500788-87-4。 | |||
T65588 |
(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid
|
Others | Others |
(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65588,CAS号为 936630-57-8。 | |||
T67273 |
(R)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(R)-1-phenylethyl]-1-phthalazinamine
|
Others | Others |
(R)-4-[2-(Diphenylphosphino)-1-naphthalenyl]-N-[(R)-1-phenylethyl]-1-phthalazinamine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67273。 | |||
T1725 |
Y-27632 dihydrochloride
反式-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐,Y-27632 2HCl |
ROCK; Apoptosis | Apoptosis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells |
Y-27632 dihydrochloride (Y-27632 2HCl) 是一种 ROCK-I 和 ROCK-II 抑制剂,具有口服有效性、ATP 竞争性。Y-27632 dihydrochloride 还抑制分离诱导的小鼠前列腺干或祖细胞凋亡。 | |||
T65603 |
(2R,4R)-4-Methylpiperidine-2-carboxylic acid
|
Others | Others |
(2R,4R)-4-Methylpiperidine-2-carboxylic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65603,CAS号为 74892-81-2。 | |||
T15190 |
(S,R,S)-AHPC-PEG4-NH2 hydrochloride
E3 ligase Ligand-Linker Conjugates 7,VH032-PEG4-NH2 hydrochloride,VHL Ligand-Linker Conjugates 4 hydrochloride |
Others | Others |
(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology. | |||
T66178 |
(2R,4R)-Ethyl 4-methylpiperidine-2-carboxylate
|
Others | Others |
(2R,4R)-Ethyl 4-methylpiperidine-2-carboxylate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66178,CAS号为 74892-82-3。 | |||
T70070 |
Cisapride tartrate
|
Others | Others |
Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Cisapride was indicated for the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease. The Food and Drug Administration (FDA) in America stopped the marketing of cisapride as of 14th July 2000. They had received at least 341 reports o... | |||
T66393 |
(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid hydrochloride
|
Others | Others |
(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid hydrochloride 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66393,CAS号为 1204818-19-8。 | |||
T67220 |
(R)-2-Amino-2-(4-fluorophenyl)acetic acid
|
||
(R)-2-Amino-2-(4-fluorophenyl)acetic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67220,CAS号为 93939-74-3。 | |||
T64973 |
(R)-2-Amino-3-(4-fluorophenyl)propanoic acid
|
||
(R)-2-Amino-3-(4-fluorophenyl)propanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64973,CAS号为 18125-46-7。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN2296 |
Vinaginsenoside R4
越南参皂苷R4 |
Others | Others |
Vinaginsenoside R4 是分离自水培人参的叶子中。它能够抑制黑色素的生物合成,并增强斑马鱼的色素沉着,对 melan-a 细胞没有任何细胞毒性作用。 | |||
T8281 |
(R)-Sulforaphane
L-Sulforaphane,(R)-1-异硫氰酰-4-(甲基亚磺酰)丁烷 |
Nrf2 | Immunology/Inflammation |
L-Sulforaphane 是高效的Keap1/Nrf2/ARE途径诱导剂。与 S-异构体相比,它对大鼠肝脏和肺部的致癌解毒酶系统的诱导能力更强。 | |||
TN5798 |
(R)-4-Methoxydalbergione
(+)-4-Methoxydalbergione,(R)-4-甲氧基黄檀醌 |
||
(R)-4-Methoxydalbergione 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5798,CAS号为 4646-86-0。 | |||
T40942 |
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone
|
Others | Others |
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, an antiangiogenic homoisoflavonoid, exhibits activity against human retinal microvascular endothelial cells. | |||
T10938 |
D-Kynurenine
D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103 |
GPR; AhR; Endogenous Metabolite | Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism |
D-Kynurenine (ZINC901103) 是 D-色氨酸的代谢物和 GPR109B 的激动剂。 D-Kynurenine 激活 AhR 并促进上皮细胞向间充质的转化。 D-Kynurenine 在 D-氨基酸氧化酶的荧光分析中用作底物。 | |||
T8078 |
Gamma-decalactone
Decan-4-olide,γ-Decalactone,丙位癸内酯 |
Others | Others |
Gamma-decalactone (Decan-4-olide) 是一种具有果味桃子味的食品添加剂。蓖麻油酸 (12-羟基-十八烷基-9-烯酸) 常作为 γ-Decalactone 的生产过程中的底物。 | |||
TN6384 |
(R)-5-Hydroxy-7-(4-hydroxyphenyl)-1-phenylheptan-3-one
|
||
(R)-5-Hydroxy-7-(4-hydroxyphenyl)-1-phenylheptan-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6384,CAS号为 1961196-24-6。 | |||
TN6364 |
(R)-5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylheptan-3-one
|
||
(R)-5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylheptan-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6364,CAS号为 68622-73-1。 | |||
TN1446 |
Bisabolol oxide A
甜没药萜醇氧化物A,[S-(R*,R*)]-α’-4-二甲基-α’-(4-甲基-3-戊烯基)-3-环己烯-1-甲醇 |
Others | Others |
Bisabololoxide A induces apoptosis in rat thymocytes. | |||
T0508 |
γ-Aminobutyric acid
Gamma-aminobutyric acid,4-Aminobutyric acid,4-氨基丁酸,γ-氨基丁酸,GABA,4-Aminobutanoic acid,Piperidic acid |
GABA Receptor; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Neuroscience |
γ-Aminobutyric acid (4-Aminobutyric acid) 是成年哺乳动物大脑中主要的抑制性神经递质,能够与离子移变 GABA 受体(GABAA) 受体和促代谢受体 (GABAB) 受体结合发挥作用。 | |||
TN6691 |
Notoginsenoside R4
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Notoginsenoside R4 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6691,CAS号为 87741-77-3。 | |||
T13355 |
Xanthorrhizol
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Antibacterial | Microbiology/Virology |
Xanthorrhizol 是从 Curcuma xanthorrhiza 中分离的一种抗菌剂。 | |||
T83552 |
(8R,8'R)-Matairesinol 4,4'-di-O-β-D-glucopyranoside
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Others | Others |
(8R,8'R)-Matairesinol 4,4'-di-O-β-D-glucopyranoside (MDG) 是Trachelospermum asiaticum中分离的天然产物。 | |||
T65265 |
N-((2S,3R,4R,5S,6R)-2-(((2R,3S,4S,5R,6S)-3,5-Dihydroxy-2-(hydroxymethyl)-6-(((2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-5-hydroxy-6-(hydroxymethyl)-4-(((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)acetamide
|
Others | Others |
N-((2S,3R,4R,5S,6R)-2-(((2R,3S,4S,5R,6S)-3,5-Dihydroxy-2-(hydroxymethyl)-6-(((2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-5-hydroxy-6-(hydroxymethyl)-4-(((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)acetamide 在生命科学相关研究中具有广泛的应用。 | |||
T65097 |
(2R,3R,4R,5R)-4-(((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal
|
Others | Others |
(2R,3R,4R,5R)-4-(((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T65097,CAS号为 33404-34-1。 | |||
T65274 |
N-((2R,3R,4R,5R)-5,6-Dihydroxy-1-oxo-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)hexan-2-yl)acetamide
|
Others | Others |
N-((2R,3R,4R,5R)-5,6-Dihydroxy-1-oxo-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)hexan-2-yl)acetamide 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T65274,CAS号为 71208-06-5。 | |||
T83517 |
(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate
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(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate (compound 7a) 是一种特定立体化学配置的二萜类化合物。 | |||
T83559 |
(3R)-6,4'-Dihydroxy-8-methoxyhomoisoflavan
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"(3R)-6,4'-Dihydroxy-8-methoxyhomoisoflavan"是一种自然产生的化合物,可从Dracaena cochinchinensis的红色树脂中提取。 | |||
T39394 |
(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone
|
Others | Others |
(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is derived exclusively from the roots of Sophora flavescens. | |||
T75607 |
(25R)-12α-Hydroxyspirost-4-en-3-one
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Others | Others |
(25R)-12α-Hydroxyspirost-4-en-3-one 是由 Nocardia globerula 作用于 Hecogenin 产生的一种次要代谢物。 | |||
TN1270 |
LPRP-Et-97543
(3R)-5,7-Dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one |
Others | Others |
(3R)-5,7-Dihydroxy-6-methyl-3-(4'-hydroxybenzyl)chroman-4-one is a natural product | |||
T83567 |
(25R)-Spirost-4-ene-3,6,12-trione
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(25R)-Spirost-4-ene-3,6,12-trione,一种可从T. terrestrisL中提取的天然产物。 | |||
T83418 |
2-((1R,2R)-2-Formyl-1,3,3-trimethylcyclohexyl)-4-hydroxy-5-isopropylbenzaldehyde
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2-((1R,2R)-2-Formyl-1,3,3-trimethylcyclohexyl)-4-hydroxy-5-isopropylbenzaldehyde 是一种具有生物活性的天然产物化合物。 | |||
TN1240 |
(2R,3R)-3,7-Dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one
3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone,(2R,3R)-3,7,4'-三羟基-5-甲氧基-8-异戊烯基二氢黄酮 |
Others | Others |
3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is a natural product | |||
T65346 |
(2R,3R,4S,5R)-2-(6-(Benzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
|
Others | Others |
(2R,3R,4S,5R)-2-(6-(Benzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T65346,CAS号为 4294-16-0。 | |||
TN2393 |
(R,E)-Deca-2-ene-4,6-diyne-1,8-diol
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Others | Others |
(R,E)-Deca-2-ene-4,6-diyne-1,8-diol is a natural from Toricellia angulata | |||
T67200 |
(1R,4aS,10aR)-methyl 7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate
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Others | Others |
(1R,4aS,10aR)-methyl 7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T67200,CAS号为 1235-74-1。 | |||
T83568 |
(25R)-Ruscogenin-3-yl α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranoside
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(25R)-Ruscogenin-3-yl α-L-rhamnopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranoside (compound 1) 为源自麦冬须 (Ophiopogon japonicus) 根的甾体皂苷。 | |||
TN2378 |
3,4-O-Isopropylidene-2-methylbutane
(2R)-2-[(4S)-2,2-二甲基-1,3-二氧戊环-4-基]-1,2-丙二醇,2-(2,2-Dimethyl-1,3-dioxolan-4-yl)propane-1,2-diol |
Others | Others |
2-(2,2-Dimethyl-1,3-dioxolan -4-yl)propane-1,2-diol is a natural product from plants | |||
TN2413 |
Diacetylpiptocarphol
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Others | Others |
Diacetylpiptocarphol has antiplasmodial activity | |||
TN2402 | Catalponol methylthiomethyl ether | Others | Others |
Catalponol methylthiomethyl ether is a natural product from plants | |||
T83554 |
(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one
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'(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one' 是倍半萜类内酯化合物。 | |||
TN2035 |
Paeonilactone A
(3R,3AR,6S,7AR)-四氢-6-羟基-3,6-二甲基-2,5(3H,4H)-苯并呋喃二酮,芍药内苷A |
Others | Others |
Paeonilactone A是一种天然产物,属于芍药科芍药属,其产品编号为 TN2035,CAS号为 98751-79-2。Paeonilactone A可用作对照参考。 | |||
T41095 |
(E)-3-(4-Methoxyphenyl)acrylic acid
(E)-3-(4-甲氧基苯基)丙烯酸 |
Glucosidase | Metabolism |
(E)-3-(4-Methoxyphenyl)acrylic acid 是从 Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. 的根茎中分离出来的一种小分子化合物。它是一种新型 α-葡萄糖苷酶抑制剂。(E)-3-(4-甲氧基苯基)丙烯酸具有保肝活性、抗失水活性、增强认知效果,并可用于降低血压血糖。 | |||
T4858 |
4-Hydroxyphenylpyruvic acid
4-羟苯基丙酮酸,4-Hydroxyphenylpyruvic acid |
Endogenous Metabolite | Metabolism |
4-Hydroxyphenylpyruvic acid 是一种苯丙氨酸代谢的中间产物,是一种酶抑制剂。 | |||
T6S1369 |
Vitexin
牡荆素,Apigenin-8-C-glucoside |
Antioxidant | oxidation-reduction |
Vitexin 是一种存在于多种药用植物(如榕树、螺旋藻)中的 c-糖基化的黄酮。 它具有广泛的药理作用,包括抗氧化,抗癌,抗炎,抗痛觉过敏和神经保护作用。 | |||
T6491 |
(-)-(S)-Equol
(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
(-)-(S)-Equol (4',7-Dihydroxyisoflavan) 是雌激素受体β的高亲和力配体。 | |||
T5S0053 |
Coptisine
黄连碱,Coptisin |
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Coptisine (Coptisin) 是一种从黄连中分离到的生物碱,是非竞争性的IDO 抑制剂,Ki=为 5.8 μM,IC50=6.3 μM。 | |||
T4S2326 |
Cornuside
7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside |
ERK; p38 MAPK; NF-κB; JNK | MAPK; NF-κB |
Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷,可用于炎症疾病的研究和促进血液循环。 它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应,用于炎性过敏性疾病中的潜能。 | |||
T82818 |
Brevianamide R
|
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Brevianamide R (compound 4) 是从发酵大米中的曲霉菌 (Aspergillus versicolor) 分离出的生物碱。 | |||
T65765 |
(R)-(-)-2-Butanol
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Others | Others |
(R)-(-)-2-Butanol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T65765,CAS号为 14898-79-4。 | |||
T35624 |
Ajoene
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Others | Others |
Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 µg/ml) and Gram-negative bacteria (MICs = 136-200 µg/ml), as well as yeasts (MICs = 10-20 µg/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 µM), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 µM).2It reduces... | |||
T37452 |
Stephacidin B
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Others | Others |
Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc... | |||
T36000 |
3-Hydroxyterphenyllin
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Others | Others |
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi... | |||
T38330 |
Collinin
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Others | Others |
Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a... | |||
T36448 |
(E)-Ajoene
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Others | Others |
(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fungi (MICs = 15-50 μg/ml).1(E)-Ajoene inhibits proliferation of a variety of cancer cells, including MDA-MB-231 breast, HeLa cervical, and WHCO1 esophageal cancer cells (IC50s = 18.6, 61, and 39.2 μM, respectively).2It also inhibits human glutathione reductase andT. cruzitrypanoth... |
Cat. No. | Product Name | Species | Expression System |
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TMPY-01052 |
R-Cadherin/CDH4 Protein, Human, Recombinant (His)
R-CAD,cadherin 4, type 1, R |
Human | HEK293 Cells |
The cadherin superfamily is a large family that engage in both homo- and heterotypic, calcium-dependent, cell-cell adhesion events, and can be divided into at least four subfamilies based on the extracellular (EC) regions and cytoplasmic domains, that is: classical cadherins, desmosomal cadherins, protocadherins, and cadherin-like molecules. Human cadherin 4, type 1, R-cadherin (retinal), also known as CDH4, CAD4 and RCAD, is a classical cadherin from the cadherin superfamily. It is a calcium-de... | |||
TMPK-00708 |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)
TRAIL R1,APO2,DR4,CD261,... |
Human | HEK293 Cells |
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations. | |||
TMPY-01055 |
IL-4R Protein, Human, Recombinant (His)
interleukin 4 receptor,I... |
Human | HEK293 Cells |
IL-4R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.18 kDa and the accession number is P24394-1. | |||
TMPY-05277 |
IL-4R Protein, Human, Recombinant (hFc)
IL4R,IL4RA,CD124 |
Human | HEK293 Cells |
IL-4R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is P24394-1. | |||
TMPK-00706 |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi)
DR4,MGC9365,TNFRSF10A,TR... |
Human | HEK293 Cells |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220. | |||
TMPK-00707 |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated
TNFRSF10A,CD261,DR4,APO2,TR |
Human | HEK293 Cells |
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.7 kDa and the accession number is O00220. | |||
TMPJ-00387 |
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Soluble IL-4R-alpha,Interleukin-<... |
Mouse | HEK293 Cells |
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ... | |||
TMPY-01065 |
GM-CSFR alpha Protein, Human, Recombinant (His)
GM-CSF-R-α,colony stimulating factor 2 |
Human | HEK293 Cells |
GM-CSFR alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P15509-1. | |||
TMPY-02030 |
CD82 Protein, Human, Recombinant (His)
CD82 molecule,SAR2,R2,KAI-1,4F9,K... |
Human | HEK293 Cells |
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud... | |||
TMPK-00710 |
Claudin-4 Protein-VLP, Human, Recombinant
Claudin4,CLDN4,Claudin-4,CPET... |
Human | HEK293 Cells |
Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs in... | |||
TMPK-00273 |
IL-13Ra1 Protein, Human, Recombinant (hFc)
NR4,CD213A1,IL-13 R alpha 1,CT19,... |
Human | HEK293 Cells |
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2. IL-13Ra1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells... | |||
TMPK-00272 |
IL-13RA1 Protein, Human, Recombinant (His & Avi), Biotinylated
AI882074,IL-13 R alpha 1,IL-13 R ... |
Human | HEK293 Cells |
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2. IL-13RA1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HE... | |||
TMPY-05060 |
BAFFR/TNFRSF13C Protein, Human, Recombinant (hFc)
BROMIX,BAFFR,CD268,BAFF-R,pr<... |
Human | HEK293 Cells |
BAFFR/TNFRSF13C Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.9 kDa and the accession number is Q5H8V1. | |||
TMPK-00238 |
IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi)
CD132,gammaC,γC,IMD4,IL2RG,SCIDX1,CIDX,IL-... |
Human | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Human, Recombinant (His... | |||
TMPY-06385 |
BAFFR/TNFRSF13C Protein, Human, Recombinant (hFc & Avi), Biotinylated
BAFFR,tumor necrosis factor |
Human | HEK293 Cells |
BAFFR/TNFRSF13C Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 35.79 kDa and the accession number is Q5H8V1. | |||
TMPK-00987 |
IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
IL-2 R γ/CD132,IL-2 R gamma,IMD4,... |
Cynomolgus | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein (Primary Amine Labeling)... | |||
TMPK-00986 |
IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)
SCIDX1,IL2RG,gammaC,γC,CIDX,IL-2 R γ/CD132... |
Cynomolgus | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant... | |||
TMPK-00239 |
IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi), Biotinylated
SCIDX,IMD4,IL-2 R gamma,CD132,SCIDX1,IL-2 ... |
Human | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Human, Recombinant (His... | |||
TMPK-00694 |
CD1A Protein, Human, Recombinant (His)
CD1,HTA1,FCB6,T6,R4,CD1a |
Human | HEK293 Cells |
CD1 proteins are a family of major histocompatibility complex (MHC) class I-like antigen-presenting molecules that present lipids to T cells. The cytoplasmic tails (CTs) of all human CD1 isoforms, with the exception of CD1a, contain tyrosine-based sorting motifs, responsible for the internalization of proteins by the clathrin-mediated pathway. CD1a closer to MHC class I in its trafficking and potential antigen-loading compartments among CD1 isoforms. | |||
TMPK-00490 |
GM-CSFR alpha Protein, Cynomolgus, Recombinant (His)
CSF2RY,SMDP4,GMCSFR-α,GMR |
Cynomolgus | HEK293 Cells |
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mamm... | |||
TMPK-00930 |
GM-CSFR alpha Protein, Mouse, Recombinant (His)
CSF2RAX,CSF2RX,CD116,CSF2RAY,GM-C... |
Mouse | HEK293 Cells |
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian... | |||
TMPY-02673 |
IGSF8 Protein, Mouse, Recombinant (hFc)
PGRL,ESTM34,EWI-2,AU041109,immuno... |
Mouse | HEK293 Cells |
IGSF8 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.8 kDa and the accession number is A0A0R4J117. | |||
TMPY-03077 |
IGSF8 Protein, Mouse, Recombinant (His)
R75384,KCT-4,AU041109,im... |
Mouse | HEK293 Cells |
IGSF8 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.2 kDa and the accession number is A0A0R4J117. | |||
TMPK-00254 |
GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated
GM-CSF-R-α,GMR-α,GMR-alpha,GM-CSF... |
Human | HEK293 Cells |
In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed... | |||
TMPY-05482 |
IL-4R Protein, Mouse, Recombinant (hFc)
interleukin 4 receptor,I... |
Mouse | HEK293 Cells |
IL-4R Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.1 kDa and the accession number is AAB87750.1. | |||
TMPY-02009 |
IL-4R Protein, Mouse, Recombinant (His)
interleukin 4 receptor,I... |
Mouse | HEK293 Cells |
IL-4R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is P16382-1. | |||
TMPY-05739 |
IL-4R Protein, Cynomolgus, Recombinant (hFc)
interleukin 4 receptor |
Cynomolgus | HEK293 Cells |
IL-4R Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.48 kDa and the accession number is G7Q0S7. | |||
TMPY-05307 |
IL-4R Protein, Cynomolgus, Recombinant (His)
interleukin 4 receptor |
Cynomolgus | HEK293 Cells |
IL-4R Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.2 kDa and the accession number is G7Q0S7. | |||
TMPY-02914 |
IL-4R Protein, Rat, Recombinant (His)
interleukin 4 receptor,I... |
Rat | HEK293 Cells |
IL-4R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is Q63257-1. | |||
TMPH-03116 |
IL-4R Protein, Pig, Recombinant (His)
IL4R,Interleukin-4 r... |
Sus scrofa (Pig) | E. coli |
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. IL-4R Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted mo... | |||
TMPY-03584 |
IL-4R Protein, Rat, Recombinant (hFc)
Il4ra,IL4R,inter |
Rat | HEK293 Cells |
IL-4R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.9 kDa and the accession number is Q63257-1. | |||
TMPY-01348 |
CD200R4 Protein, Mouse, Recombinant (His)
Cd200r4,CD200 receptor <... |
Mouse | HEK293 Cells |
CD200R4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is Q6XJV4. | |||
TMPY-06520 |
IL-4R alpha & IL-13R alpha 1 Heterodimer Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
IL-4R alpha & IL-13R alpha 1 Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 63.52 kDa and the accession number is NP_000409.1. | |||
TMPY-05111 |
IL-4R Protein, Human, Recombinant (His), Biotinylated
IL-4RA,IL4RA,CD124 |
Human | HEK293 Cells |
IL-4R Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.2 kDa and the accession number is P24394-1. | |||
TMPY-01404 |
CD200R4 Protein, Mouse, Recombinant (hFc)
CD200 receptor 4,F630107N04 |
Mouse | HEK293 Cells |
CD200R4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is Q6XJV4. | |||
TMPY-00816 |
GM-CSFR alpha Protein, Human, Recombinant (hFc)
CSF2RAX,CSF2R,CD116,CSF2RY,GM-CSF... |
Human | HEK293 Cells |
GM-CSFR alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.2 kDa and the accession number is P15509-1. | |||
TMPH-01186 |
CYP2C9 Protein, Human, Recombinant (His & Myc)
CYP2C10,Cytochrome P450 2C9,S-mephenytoin ... |
Human | E. coli |
CYP2C9 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-01163 |
Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His)
Rtn4r,NgR,NgR1,... |
Mouse | HEK293 Cells |
Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is Q99PI8. | |||
TMPY-06577 |
IL-4R Protein, Human, Recombinant (His & Avi), Biotinylated
CD124,IL4RA,IL4R |
Human | HEK293 Cells |
IL-4R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 26.99 kDa and the accession number is NP_000409.1. | |||
TMPY-03144 |
Nogo Receptor/RTN4R Protein, Human, Recombinant (His)
NGR,reticulon 4 recepto<... |
Human | HEK293 Cells |
Nogo Receptor/RTN4R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9BZR6. | |||
TMPK-01200 |
Nogo Receptor/RTN4R Protein, Cynomolgus, Recombinant (His)
NGR,NOGOR,RTN4R... |
Cynomolgus | HEK293 Cells |
NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes. | |||
TMPY-03318 |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His)
tumor necrosis factor re... |
Rhesus | HEK293 Cells |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is XP_001107922.1. | |||
TMPY-01381 |
DcR2/TRAIL R4 Protein, Human, Recombinant (His)
CD264,TRAILR4,tumor<... |
Human | HEK293 Cells |
DcR2/TRAIL R4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is Q9UBN6. | |||
TMPY-01719 |
DR4/TRAIL R1 Protein, Human, Recombinant (hFc)
TRAILR1,tumor necrosis f... |
Human | HEK293 Cells |
DR4/TRAIL R1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.3 kDa and the accession number is O00220. | |||
TMPY-03317 |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc)
tumor necrosis factor re... |
Rhesus | HEK293 Cells |
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is XP_001107922.1. | |||
TMPY-01056 |
Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc)
NOGOR,reticulon 4 recept... |
Human | HEK293 Cells |
Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 73 kDa and the accession number is Q9BZR6. | |||
TMPY-05481 |
DcR2/TRAIL R4 Protein, Human, Recombinant (hFc)
TRUNDD,TRAIL-R4,tumo... |
Human | HEK293 Cells |
DcR2/TRAIL R4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.5 kDa and the accession number is Q9UBN6. | |||
TMPY-01720 |
DR4/TRAIL R1 Protein, Human, Recombinant (His)
APO2,tumor necrosis factor r<... |
Human | HEK293 Cells |
DR4/TRAIL R1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is O00220. | |||
TMPY-01221 |
Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc)
NgR1,reticulon 4 recepto... |
Mouse | HEK293 Cells |
Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q99PI8. | |||
TMPY-06646 |
IL-4R & IL2RG Heterodimer Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
IL-4R & IL2RG Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.74 kDa and the accession number is NP_000409.1. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMIH-0271 |
Hydroxyzine dihydrochloride-d4
(R)-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy-1,1,2,2-d4)ethan-1-ol dihydrochloride |
||
Hydroxyzine dihydrochloride-d4 是 Hydroxyzine dihydrochloride 的氘代化合物。Hydroxyzine dihydrochloride 的 CAS 号为 2192-20-3。Hydroxyzine dihydrochloride是一种苯二氮卓抗组胺剂,是可口服的组胺 H1 受体和血清素拮抗剂,可有效治疗慢性荨麻疹、皮炎和组胺介导的瘙痒。它还可以作为止吐剂和镇静剂,有缓解焦虑和紧张的作用。 | |||
T11247 |
Etravirine D4
R-165335 D4,TMC-125 D4,依曲韦林 D4 |
Others | Others |
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine. | |||
TMIH-0272 |
Hydroxyzine dihydrochloride-d8
(R)-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy-1,1,2,2-d4)ethan-1,1,2,2-d4-1-ol dihydrochloride |
||
Hydroxyzine dihydrochloride-d8 是 Hydroxyzine dihydrochloride 的氘代化合物。 | |||
TMIH-0273 |
Hydroxyzine dihydrochloride-d10
(R)-2-(2-(4-((4-chlorophenyl)(phenyl)methyl)pi perazin-1-yl-2,2,3,3,5,5,6,6-d8)ethoxy)ethan-1, 1-d2-1-ol dihydrochloride |
||
Hydroxyzine dihydrochloride-d10 是 Hydroxyzine dihydrochloride 的氘代化合物。 | |||
TMID-0149 |
20 (R)-Hydroxy Prednisolone-d4
|
||
20 (R)-Hydroxy Prednisolone-d4 是 20 (R)-Hydroxy Prednisolone 的氘代化合物。20 (R)-Hydroxy Prednisolone 的 CAS 号为 15847-24-2。 | |||
TMID-0154 |
(1RS,2RS,5R)-Menthol-1,2,6,6-d4
|
||
(1RS,2RS,5R)-Menthol-1,2,6,6-d4 是 (1RS,2RS,5R)-Menthol 的氘代化合物。(1RS,2RS,5R)-Menthol 的 CAS 号为 1369536-10-6。 | |||
TMIH-0412 |
Oseltamivir-d3 acid(3R,4S,5S)
|
||
Oseltamivir-d3 acid(3R,4S,5S) 是 Oseltamivir acid(3R,4S,5S) 的氘代化合物。 | |||
TMIJ-0141 |
(S)-Amlodipine-d4
|
||
(S)-Amlodipine-d4 是 (S)-Amlodipine 的氘代化合物。(S)-Amlodipine 的 CAS 号为 103129-82-4。Levamlodipine 是一种二氢吡啶钙通道阻滞剂,具有舒张血管的作用,可用于高血压和心绞痛的研究。 | |||
T35513 |
13C15-Nivalenol
13C15-Nivalenol |
||
13C15-Nivalenol is intended for use as an internal standard for the quantification of nivalenol by GC- or LC-MS. Nivalenol is a trichothecene mycotoxin that has been found inFusarium.1It is lethal to mice (LD50= 6.9 mg/kg).2Nivalenol (5, 10, and 15 mg/kg) also induces thymic, splenic, and Peyer's patch cell apoptosis in mice.3 1.Yang, Z., Concannon, J., Ng, K.S., et al.Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulationSci. Rep.63026... | |||
T38297 |
Ribavirin-13C5
Ribavirin-13C5 |
||
Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro... | |||
T35790 |
Palmitic acid-1,2,3,4-13C4
Palmitic Acid-13C (C1, C2, C3, and C4 labeled) |
||
Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula... |