Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T73341 |
Quipazine
2-(1-哌嗪基)喹啉 |
Others | Others |
Quipazine 是一种5-HT 激动剂,取代大鼠内皮层中 5-HT3R 的 [3H]GR65630 的Ki 值为 1.4 nM。Quipazine 对SARS-CoV-2具有抗病毒活性,EC50值为 31.64 μM。Quipazine 在外周模型中表现为 5-HT3R 的激动剂,可用于神经疾病研究。 | |||
T23212 |
Quipazine dimaleate
|
5-HT Receptor | GPCR/G Protein; Neuroscience |
Quipazine dimaleate 是一种选择性 5-HT3 激动剂。 | |||
T71792 |
Quipazine maleate
|
Others | Others |
Quipazine maleate is a selective 5-HT receptor agonist that promotes the proliferation and apoptosis of human hepatocyte strain of L-02 strain and could also exert an excitatory effect on raphe neurons via stimulation of 5-HT2A receptors. Like quipazine, quipazine derivatives produce contracture of smooth muscle organs and bronchospasm. | |||
T24537 |
N-Methylquipazine
NMethylquipazine,J366.838J,N-Methylquipazine;NMethylquipazine,N-Methylquipazine |
Others | Others |
N-Methylquipazine is an agonist of 5-HT3. It has almost the same affinity for 5-HT3 sites as quipazine. | |||
T23042 |
N-Methylquipazine dimaleate
|
Others | Others |
5-HT3 agonist | |||
T68141 |
Seganserin
|
5-HT Receptor | GPCR/G Protein; Neuroscience |
Seganserin 是一种非选择性5-羟色胺2-HT 受体拮抗剂,可逆转了氟西汀和喹帕嗪对黄体酮诱导的食欲亢进,抑郁和痛觉的抑制作用,逆转氟西汀和喹帕嗪诱导的抗抑郁和镇痛作用。 |