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Cat. No. | Product Name | Target | Signaling Pathways |
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TP1059 |
Peptide YY (PYY) (3-36), human
Peptide YY (3-36) |
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) 是一种肠胃激素肽,可以激动Y2受体,具有降低食欲的功效。 | |||
TP1762 |
Peptide YY (PYY), human
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Peptide YY (PYY), a novel 36 amino-acid amidated hormone is a component of the complex neuroendocrine control process.Peptide YY (PYY) can mediate its effects through the Neuropeptide Y receptors. | |||
TP1058 |
Peptide YY (PYY) (3-36), human TFA
Peptide YY (3-36) (TFA) |
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Peptide YY (PYY) (3-36), human (TFA) is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite[1]. | |||
T64716 |
Peptide YY (PYY) (3-36), human trifluoroacetate
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Peptide YY (PYY) (3-36), human trifluoroacetate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64716。 | |||
T75773 |
Peptide YY (PYY) (3-36), porcine TFA
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Peptide YY (PYY) (3-36), porcine TFA,为一种肠胃激素肽,作用于Y2受体,具有降低食欲的功能。 | |||
T35631 |
Peptide YY (human) (trifluoroacetate salt)
Peptide Tyrosine Tyrosine |
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Peptide YY (PYY) is a 36-amino acid peptide and anorectic gut hormone agonist for the neuropeptide Y receptors Y1, Y2, Y5, and Y6 with EC50 values of 0.7, 0.58, 1, and 0.8 nM, respectively, for supression of forskolin-induced cAMP accumulation. PYY is cleaved in vivo to PYY (3-36) . Release of PYY occurs postprandially in proportion to calorie intake from intestinal enteroendocrine L cells, indicating it may be a satiety signal. In humans, PYY inhibits food intake and gastrointestinal transit in... | |||
T81672 |
Nisotirostide
LY-3457263 |
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Nisotirotide (LY-3457263)为PYY类似物激动剂,适用于2型糖尿病及肥胖症研究领域。 | |||
T37528 |
tBPC
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Others | Others |
Positive allosteric modulator of neuropeptide Y receptor 4 (Y4R). Potentiates Y4R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC50 values are 0.03, 0.4 and 0.5 nM respectively). Shows selectivity for Y4R over Y1R, Y2R and Y5R. Schubert et al (2017) Identification and characterization of the first selective Y4 receptor positive allosteric modulator. J.Med.Chem. 60 7605 PMID:28795803 | |||
T14382 |
AZD7687
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Others | Others |
AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial TAG excursion with a steep concent |
Cat. No. | Product Name | Species | Expression System |
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TMPH-01852 |
Peptide YY/PYY Protein, Human, Recombinant (GST)
Peptide tyrosine tyrosine,PYY-I,PYY,Peptid... |
Human | E. coli |
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Peptide YY/PYY Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.1 kDa and the accession number is P10082. | |||
TMPH-02823 |
Peptide YY/PYY Protein, Mouse, Recombinant (GST)
Peptide tyrosine tyrosine,Pyy,Peptide YY |
Mouse | E. coli |
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. | |||
TMPY-00286 |
Neuropeptide Y Protein, Human, Recombinant (hFc)
PYY4,neuropeptide Y |
Human | HEK293 Cells |
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. NPY is a neuromodulator that is widely expressed throughout the central nervous system (CNS) and is consecrated with classic neurotransmitters including GABA and glutamate. NPY/Agouti-related protein (AgRP) ne... | |||
TMPH-01767 |
NPY2R Protein, Human, Recombinant (His)
Neuropeptide Y receptor type 2,NPY-Y2 receptor,NPY2R |
Human | E. coli |
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. NPY2R Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 48.8 kDa and the accession number is P49146. |