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Search Results for " pyridoxal "

Targets Recommended: Endogenous Metabolite

10

抑制剂 & 化合物

8

天然产物

9

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T78509	Pyridoxal Pyridoxaldehyde	Endogenous Metabolite	Metabolism
	Pyridoxal为维生素B6的一种活性形态。
T5314	pyridoxal isonicotinoyl hydrazone 吡哆醛异烟酰肼,PIH	Others	Others
	pyridoxal isonicotinoyl hydrazone (PIH) 是亲脂的三价铁螯合剂，具有高铁螯合特性。
T3578L	Pyridoxal calcium phosphate	Others	Others
	Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), known as an active form of vitamin B6, is a coenzyme involved in many enzymatic reactions.
T38294	4-Deoxypyridoxine hydrochloride	S1P Receptor	GPCR/G Protein
	4-Deoxypyridoxine hydrochloride 通过抑制 S1P 裂解酶 (SPL) 活性来抑制细胞内 S1P 的降解，与 S1P 一样，减少化学诱导的胰岛素瘤细胞系的细胞凋亡。
T75316	Pyridoxamine 5′-phosphate	Others	Others
	Pyridoxamine 5′-phosphate 是维生素 B6 与磷酸结合的活性形式。Pyridoxamine 5′-phosphate 是 Pyridoxal 5'-phosphate hydrate 的胺化形式，是多种酶的中心代谢物、强力抗氧化剂、维生素 B6 和酶底物的辅助因子。Pyridoxamine 5′-phosphate 能与 Pyridoxal 5'-phosphate hydrate 相互转化。
T78364	Alanine aminotransferase	Endogenous Metabolite	Metabolism
	Alanine aminotransferase是一种酶，能促进L-丙氨酸与2-氧代谷氨酸之间可逆的转化为丙酮酸和L-谷氨酸。
T29033	U-7524 2-Aminooxyacetic acid,U 7524,Aminooxyacetic acid,U7524,AOAA	Others	Others
	U-7524, also known as AOAA and Aminooxyacetic acid, is an inhibitor of 4-aminobutyrate aminotransferase (GABA-T). AOAA is also a general inhibitor of pyridoxal phosphate (PLP)-dependent enzymes (this includes GABA-T). It functions as an inhibitor by attac
T62150	Cap-dependent endonuclease-IN-25	Others	Others
	Cap-dependent endonuclease-IN-25 是一种大环吡啶并三嗪衍生物，也是一种 cap-dependent 核酸内切酶 (CEN) 的有效抑制剂。Cap-dependent endonuclease-IN-25 具有潜力进行由 Orthomyxoviridae 家族病毒引起的病毒感染的研究。
T73614	Tyrosine decarboxylase	Others	Others
	Tyrosine decarboxylase (TDC; TyrDC)，即酪氨酸脱羧酶，广泛存在于植物、昆虫和不同微生物中，常用于生化研究。Tyrosine decarboxylase 是一种5'-磷酸吡哆醛 (PLP) 依赖性脱羧酶，可以催化酪氨酸中羧基的去除，产生酪胺和二氧化碳。
T79929	L-Methionine γ-lyase Methionine lyase	Others	Others
	L-Methionine γ-lyase（Methionine lyase）是一种依赖磷酸吡哆醛的多功能酶，专门催化L-蛋氨酸（L-methionine）及其类似物的α, γ-裂解反应。该酶因其抗癌和抗感染活性被用于相关疾病的研究，同时也适用于同型半胱氨酸血症研究领域。

化合物

Cat.No: T78509

Synonym: Pyridoxaldehyde

Target: Endogenous Metabolite

pyridoxal isonicotinoyl hydrazone

Cat.No: T5314

Synonym: 吡哆醛异烟酰肼,PIH

Target: Others

Pyridoxal calcium phosphate

Cat.No: T3578L

Target: Others

4-Deoxypyridoxine hydrochloride

Cat.No: T38294

Target: S1P Receptor

Pyridoxamine 5′-phosphate

Cat.No: T75316

Target: Others

Alanine aminotransferase

Cat.No: T78364

Target: Endogenous Metabolite

Cat.No: T29033

Synonym: 2-Aminooxyacetic acid,U 7524,Aminooxyacetic acid,U7524,AOAA

Target: Others

Cap-dependent endonuclease-IN-25

Cat.No: T62150

Target: Others

Tyrosine decarboxylase

Cat.No: T73614

Target: Others

L-Methionine γ-lyase

Cat.No: T79929

Synonym: Methionine lyase

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3578	Pyridoxal phosphate PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate	Reverse Transcriptase; Endogenous Metabolite	Metabolism; Microbiology/Virology
	Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式，可抑制逆转录酶活性，用于研究迟发性运动障碍症。
T8083	Pyridoxal 5'-phosphate monohydrate Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛	Others	Others
	Pyridoxal 5-phosphate monohydrate 是维生素B6的活性形式，也是多种酶的重要辅因子。它是维生素 B6 在细胞内磷酸化过程中最重要的辅酶变异体，能够与其他变异体（如 PNP 、 PMP）发生互换。
T5085	Pyridoxal 5'-phosphate hydrate Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),5-磷酸吡多醛水合物,PLP,Pyridoxal 5'-phosphate hydrate	Others; Endogenous Metabolite	Metabolism; Others
	Pyridoxal 5'-phosphate hydrate (PLP) 是内源性代谢产物的一种。
T4761	Pyridoxal hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	Pyridoxal hydrochloride 是内源性代谢产物的一种。
T0710	L-Cycloserine Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,环丝氨酸,(S)-4-Amino-3-isoxazolidone	HIV Protease; GABA Receptor	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	L-Cycloserine ((-)-Cycloserine) 不可逆地抑制大肠杆菌以及各种动物大脑中的 GABA 吡哆醛 5'-磷酸依赖性转氨酶，导致体内抑制性神经递质 γ-氨基丁酸水平升高。
T0973L	Pyridoxine hydrochloride Pyridoxine HCl,吡哆醇盐酸盐,Pyridoxol (hydrochloride),吡哆醇盐酸盐(维生素B6),Vitamin B6 (hydrochloride),Vitamin B6	Nrf2; Endogenous Metabolite	Immunology/Inflammation; Metabolism
	Pyridoxine hydrochloride (Vitamin B6) 是一种吡啶衍生物。在于阿尔茨海默病细胞模型中，通过 Nrf-2/HO-1 途径发挥抗氧化作用。
T0973	Pyridoxine 吡哆醇,Pyridoxol,Vitamin B6,Gravidox,吡多素（维生素B6）	PLK; Nrf2; Endogenous Metabolite	Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism
	Pyridoxine (Vitamin B6) 是一种吡啶衍生物，通过 Nrf-2/HO-1 途径发挥抗氧化作用，作用于阿尔茨海默病细胞模型。
T4920	2-Ketoglutaric acid Sodium Oxoglutaric acid,AKG,2-oxoglutarate monobasic,LPHA-酮戊二酸钠,α-Ketoglutaric acid sodium salt	Tyrosinase; Endogenous Metabolite	Metabolism; Proteases/Proteasome
	2-Ketoglutaric acid Sodium (AKG) 是一种三羧酸循环的中间产物，它可以由谷氨酸通过谷氨酸脱氢酶氧化脱氨产生，也可以作为磷酸吡哆醛依赖的转氨化反应的产物(由支链氨基酸转氨酶介导)，其中谷氨酸是常见的氨基供体。

天然产物

Pyridoxal phosphate

Cat.No: T3578

Synonym: PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Target: Reverse Transcriptase, Endogenous Metabolite

Pyridoxal 5'-phosphate monohydrate

Cat.No: T8083

Synonym: Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate,5-磷酸吡哆醛

Target: Others

Pyridoxal 5'-phosphate hydrate

Cat.No: T5085

Synonym: Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),5-磷酸吡多醛水合物,PLP,Pyridoxal 5'-phosphate hydrate

Target: Others, Endogenous Metabolite

Pyridoxal hydrochloride

Cat.No: T4761

Target: Others, Endogenous Metabolite

Cat.No: T0710

Synonym: Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,环丝氨酸,(S)-4-Amino-3-isoxazolidone

Target: HIV Protease, GABA Receptor

Pyridoxine hydrochloride

Cat.No: T0973L

Synonym: Pyridoxine HCl,吡哆醇盐酸盐,Pyridoxol (hydrochloride),吡哆醇盐酸盐(维生素B6),Vitamin B6 (hydrochloride),Vitamin B6

Target: Nrf2, Endogenous Metabolite

Cat.No: T0973

Synonym: 吡哆醇,Pyridoxol,Vitamin B6,Gravidox,吡多素（维生素B6）

Target: PLK, Nrf2, Endogenous Metabolite

2-Ketoglutaric acid Sodium

Cat.No: T4920

Synonym: Oxoglutaric acid,AKG,2-oxoglutarate monobasic,LPHA-酮戊二酸钠,α-Ketoglutaric acid sodium salt

Target: Tyrosinase, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02870	PDXP Protein, Mouse, Recombinant (His & SUMO) Pdxp,Pyridoxal phosphate phosphatase,Chronophin,	Mouse	E. coli
	Functions as a pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP and therefore plays a role in vitamin B6 metabolism. Also functions as a protein serine phosphatase that specifically dephosphorylates 'Ser-3' in proteins of the actin-depolymerizing factor (ADF)/cofilin family like CFL1 and DSTN. Thereby, regulates cofilin-dependent actin cytoskel...
TMPH-02869	PDXP Protein, Mouse, Recombinant (His) Chronophin,Pdxp,Pyridoxal phosphate phosphatase,	Mouse	P. pastoris (Yeast)
	PDXP Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 33.5 kDa and the accession number is P60487.
TMPH-01990	PDXP Protein, Human, Recombinant (His) PDXP,Chronophin,Pyridoxal phosphate phosphatase	Human	Baculovirus Insect Cells
	PDXP Protein, Human, Recombinant (His) is expressed in Baculovirus.
TMPY-03754	SCLY Protein, Human, Recombinant (His) selenocysteine lyase,hSCL,SCL	Human	Baculovirus Insect Cells
	SCLY, also known as selenocysteine lyase, belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. It is a novel enzyme that exclusively decomposes L-selenocysteine into L-alanine and H2Se in various mammalian tissues. SCLY contains pyridoxal 5'-phosphate and weighs approximately 85,000. SCLY participates in selenoamino acid metabolism. It employs one cofactor, pyridoxal phosphate. Its maximum reactivity is at about pH 9.0. It was shown that 1 mol of selenocysteine is conver...
TMPY-03445	Aspartate Aminotransferase Protein, Human, Recombinant (His) ASTQTL1,glutamic-oxaloacetic transaminase 1, soluble,cCAT,cA...	Human	E. coli
	GOT1 (Glutamic-Oxaloacetic Transaminase 1) is a Protein Coding gene. GOT1 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme that exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. GOT1 is an important regulator of levels of glut...
TMPH-03329	Mcpt2 Protein, Rat, Recombinant (His & Myc) Mast cell protease 2,Mcpt2,Mast cell protease II,Group-speci...	Rat	E. coli
	This enzyme, isolated from small intestine, specifically inactivates the apo forms of a certain group of intracellular pyridoxal phosphate-requiring enzymes. It has chymotrypsin-like specificity towards small substrates. Mcpt2 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P00770.
TMPY-01099	GPT Protein, Rat, Recombinant (His) Gpt1,ALAT,glutamic-pyruvate transaminase (alanine aminotrans...	Rat	Baculovirus Insect Cells
	Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (GPT), is a pyridoxal enzyme that belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily. Gpt / Gpt1 / ALT catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. Gpt / Gpt1 / ALT is expressed in the liver, kidney, heart, and skeletal musc...
TMPY-03503	GCSH Protein, Human, Recombinant (His) glycine cleavage system protein H (aminomethyl carrier),NKH,...	Human	E. coli
	Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). GCSH is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in GCSH gene are a cause of nonketotic h...
TMPY-01100	GPT2 Protein, Rat, Recombinant (His) glutamic pyruvate transaminase (alanine aminotransferase) 2	Rat	Baculovirus Insect Cells
	Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (Gpt), is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. As a key enzyme for gluconeogenesis, Gpt is a widely-used serum marker for liver injury. Two ALT isoenzymes have been identified, ALT1 and ALT2 (GPT1 and GPT2), which are encoded by separate genes and share ...

重组蛋白

PDXP Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02870

Species: Mouse

Expression System: E. coli

PDXP Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02869

Species: Mouse

Expression System: P. pastoris (Yeast)

PDXP Protein, Human, Recombinant (His)

Cat.No: TMPH-01990

Species: Human

Expression System: Baculovirus Insect Cells

SCLY Protein, Human, Recombinant (His)

Cat.No: TMPY-03754

Species: Human

Expression System: Baculovirus Insect Cells

Aspartate Aminotransferase Protein, Human, Recombinant (His)

Cat.No: TMPY-03445

Species: Human

Expression System: E. coli

Mcpt2 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03329

Species: Rat

Expression System: E. coli

GPT Protein, Rat, Recombinant (His)

Cat.No: TMPY-01099

Species: Rat

Expression System: Baculovirus Insect Cells

GCSH Protein, Human, Recombinant (His)

Cat.No: TMPY-03503

Species: Human

Expression System: E. coli

GPT2 Protein, Rat, Recombinant (His)

Cat.No: TMPY-01100

Species: Rat

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0463	Pyridoxal-d3
	Pyridoxal-d3 是 Pyridoxal 的氘代化合物。
TMIH-0464	Pyridoxal-d3 Hydrochloride
	Pyridoxal-d3 Hydrochloride 是 Pyridoxal Hydrochloride 的氘代化合物。
TMID-0152	Pyridoxine-d2 HCl
	Pyridoxine-d2 HCl 是 Pyridoxine HCl 的氘代化合物。Pyridoxine HCl 的 CAS 号为 58-56-0。Pyridoxine hydrochloride 是一种吡啶衍生物。在于阿尔茨海默病细胞模型中，通过Nrf-2/HO-1 途径发挥抗氧化作用。

同位素标记化合物

Cat.No: TMIH-0463

Pyridoxal-d3 Hydrochloride

Cat.No: TMIH-0464

Pyridoxine-d2 HCl

Cat.No: TMID-0152

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