Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37029 |
PtdIns-(3,4,5)-P3-biotin (sodium salt)
PtdIns-(3,4,5)-P3-biotin (sodium salt) |
Others | Others |
The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins. |