首页工具

登录

搜索结果

Search Results for " protein kinase c "

Targets Recommended: PKC

185

抑制剂 & 化合物

61

天然产物

1

化合物库

124

重组蛋白

1

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L3800	NF-κB 通路分子库		729 compounds
	729 个 NF-κB 信号通路相关的小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

NF-κB 通路分子库

Cat.No: L3800

Compounds: 729

Cat. No.	Product Name	Target	Signaling Pathways
TP1053L	Protein Kinase C 19-31 acetate Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Protein Kinase C 19-31 acetate(121545-65-1 free base) 是一种蛋白激酶 C (PKC) 的肽抑制剂，源自 PKCa 的假底物调节结构域（残基 19-31），在 25 位用丝氨酸取代野生型丙氨酸作为蛋白激酶 C 底物肽，用于测试蛋白激酶 C 活性。
TP1051L	Protein Kinase C Peptide Substrate acetate Protein Kinase C Peptide Substrate acetate(120253-69-2 free base)	Others	Others
	Protein Kinase C Peptide Substrate acetate(120253-69-2 free base) 以依赖于第二信使和特定衔接蛋白的方式靶向特定细胞间隔物，以响应激活 g 蛋白偶联受体、酪氨酸激酶受体或酪氨酸激酶偶联受体的细胞外信号。
TP1503	Protein Kinase C (19-36) Protein Kinase C 19-36
	Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.
TP1053	Protein Kinase C (19-31) Protein Kinase C 19-31,PKC (19-31)
	Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate pepti
T17148	TPPB	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	TPPB 是可渗透细胞的苯并内酰胺衍生蛋白的激酶 C 激活剂，Ki 值为11.9 nM。
T7648	HA-100	Myosin; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	HA-100 是蛋白激酶和ROCK 抑制剂，抑制PKG，PKA，PKC 和MLC 激酶的IC50值分别为 4、8、12 和 240 μM。
T7885	Afuresertib hydrochloride	ROCK; Akt; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells
	Afuresertib hydrochloride 是一个口服有效的，ATP 竞争性的选择性泛Akt 抑制剂，作用于Akt1、Akt2和Akt3，Ki 值分别为 0.08、2和 2.6 nM。
TP1051	Protein Kinase C Peptide Substrate PRKCE,Peptide Epsilon,PKCε
	Protein Kinase C Peptide Substrate targets specific cell spacers ina manner that is dependent on second messengers and specific adaptor proteins in response to extracellular signals that activate g protein-coupled receptors, tyrosine Kinase receptors, or
T1911	Afuresertib GSK2110183C,GSK2110183	ROCK; Akt; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells
	Afuresertib (GSK2110183) 是一个选择性，ATP 竞争性，口服有效的泛 Akt 抑制剂，作用于 Akt1、Akt2和 Akt3，Ki 值分别为 0.08、2、2.6 nM。
T14989	CMPD101	ROCK; GRK; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; GPCR/G Protein; Stem Cells
	CMPD101 是膜透性的 GRK2/3高选择性小分子抑制剂，IC50分别为 18 nM 和 5.4 nM。它针对 GRK1、GRK5 ROCK-2 和 PKCα 的选择性较小，IC50值分别为 3.1 μM，2.3 μM，1.4 μM 和 8.1 μM，可研究心衰疾病。
T12494	PKC-IN-1	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	PKC-IN-1 是 ATP-竞争性可逆 PKC 抑制剂，对人 PKCβ 和 PKCα 的 Ki 值分别为 5.3 和 10.4 nM，对人 PKCα、PKCβI、PKCβII、PKCθ、PKCγ、PKC mu 和 PKCε 的IC50值分别为 2.3、8.1、7.6、25.6、57.5、314 和 808 nM。
T14069	A-3 hydrochloride	CaMK; Casein Kinase; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Neuroscience; Stem Cells; Tyrosine Kinase/Adaptors
	A-3 hydrochloride 是一种细胞可渗透的、可逆的、ATP 竞争性非选择性拮抗剂。它抑制 PKA 、酪蛋白激酶 II 和肌球蛋白轻链激酶，Ki 值分别为4.3 µM、5.1 µM 和7.4 µM。它还抑制 PKC 和酪蛋白激酶 I 的活性，Ki 分别为 47 µM 和 80 µM。
TP1052	Protein Kinase C (19-31) (TFA)(121545-65-1,free) PKC (19-31) (TFA),Protein Kinase C (19-31) (TFA)
	Protein Kinase C (19-31) TFA, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate p
T35407	Ζ-Stat	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	ζ-Stat 是非典型的、特异性的PKC-ζ抑制剂，IC50为 5 μM。ζ-Stat 能够减少黑色素瘤细胞系的增殖并诱导细胞凋亡，在体外显示除抗肿瘤活性。
TP1955L	PKC β pseudosubstrate acetate PKC β pseudosubstrate醋酸盐,Protein kinase C beta pseudosubstrate,PKC beta pseudosubstrate,PKC β pseudosubstrate acetate (172308-76-8 Free base)	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) 是一种选择性的、细胞渗透的 PKC 抑制剂。
T13314	VTX-27	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	VTX-27 是蛋白激酶 C θ (PKC θ) 的一种选择性抑制剂，对 PKC θ 和 PKC δ 的 Ki 值分别为 0.08 nM 和 16 nM。
T2441	TAS-301 TAS 301	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	TAS-301 是一种平滑肌迁移和增殖抑制剂，能够抑制 PDGF 诱导的 PKC 的活化，可抑制大鼠颈动脉球囊损伤后的内膜增厚。
T7659	Bisindolylmaleimide IV	Others; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Others
	Bisindolylmaleimide IV 是一种蛋白激酶 C 细胞渗透抑制剂，其 IC50范围为 0.1-0.55 μM。它也抑制 PKA，IC50范围为3.1-11.8 μM。在细胞培养中，它有效抑制人巨细胞病毒(HCMV)复制，IC50为 0.2 μM。
T26019	R59949 R-59949,R 59949	Others; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Others
	R59949 是一种泛二酰甘油激酶(DGK)抑制剂，IC50为 300 nM。它通过提高内源性配体二酰甘油水平来激活蛋白激酶 C(PKC)。它强烈抑制 Ⅰ 型 DGKα 和 γ 的活性，中度减弱 Ⅱ 型 DGKθ 和 κ 的活性。
T76387	Protein kinase C substrate
	Protein kinase C substrate，蛋白激酶C的底物，关键用于蛋白质检测。作为信号转导中重要的调控元素，Protein kinase C通过特定底物的磷酸化作用发挥其功能。
T76419	Protein Kinase C γ Peptide
	Protein Kinase C γ Peptide，Protein Kinase Cγ 的肽片段，为显性共济失调的致病蛋白，能够负向调节隐性共济失调相关失联蛋白的核输入。
T8764	PKC-iota inhibitor 1	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	PKC-iota inhibitor 1 是一种蛋白激酶 C-iota(PKC-ι ℩)的抑制剂，IC50值为 0.34 μM。
T76421	Protein Kinase C β Peptide
	Protein Kinase C β Peptide为Protein Kinase Cβ的多肽片段，与高血糖降低内皮源性一氧化氮（NO）生成相关。抑制Protein Kinase Cβ能够减轻急性高血糖导致的内皮依赖性血管舒张功能障碍。
T14943	CGP60474	VEGFR; CDK; PKC	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	CGP60474 是一种高效的抗内毒素药物，抑制细胞周期蛋白依赖激酶(CDK) ，抑制 CDK1/B、CDK2/E、CDK2/a、CDK4/D、CDK5/p25、CDK7/H 和 CDK9/T 的IC50分别为 26、3、4、216、10、200 和 13 nM。它是选择性和 ATP 竞争性PKC 抑制剂。
T17019	TCS 21311 NIBR3049	GSK-3; JAK; PKC	Angiogenesis; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Stem Cells
	TCS 21311 (NIBR3049) 是一种高选择性JAK3抑制剂，IC50为 8 nM，它的选择性是 JAK1、JAK2 和 TYK2 的100倍以上，还抑制PKCα、PKCθ和GSK3β，IC50值分别为 13、68 和 3 nM。
TQ0028	EX229 Compound 991,C991	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	EX229 (C991) 是一种 AMP 活化蛋白激酶 (AMPK) 的有效变构激动剂，是苯并咪唑衍生物，其对 α1β1γ1、α2β1γ1 和 α1β2γ1 的Kd 值分别为 0.06、0.06 和 0.51 μM。
T6515	Go6976 Gö 6976	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Go6976是蛋白激酶C (PKC)的小分子抑制剂。Go6976作为研究PKC 在各种生理和病理生理过程中的作用的工具，广泛应用于生物医学研究。
T6313	Go 6983 Goe 6983	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Go 6983 是一种PKC 抑制剂，能够作用于PKCα、PKCβ、PKCγ、PKCδ和PKCζ，IC50值分别为 7、7、6、10 和 60 nM。
T76388	Protein kinase C α peptide TFA
	Protein kinase C α peptide (TFA) 为PKC-α的脂质依赖性丝氨酸/苏氨酸蛋白激酶多肽片段，关键调节细胞生存、增殖、分化、迁移及粘附等过程。
T6278	Sotrastaurin 索曲妥林,AEB071	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Sotrastaurin (AEB071) 是一种口服有效的泛 PKC 抑制剂，对 PKCθ、PKCβ、PKCα、PKCη、PKCδ 和 PKCε，Ki 分别为 0.22、0.64、0.95、1.8、2.1 和 3.2 nM。
T5600	Darovasertib LXS196	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Darovasertib (LXS196) 是一种有效的、选择性的和具有口服活性的蛋白激酶C(PKC) 抑制剂，有用于葡萄膜黑素瘤的研究潜力，对 PKCα、PKCθ 和 GSK3β 的 IC50值分别为 1.9、0.4 和 3.1 μM。
T76422	Protein Kinase C (661-671)
	Protein Kinase C (661-671) 是蛋白激酶 C (PKC) β1 亚种的片段肽。PKC 在细胞生长控制和肿瘤促进中发挥作用。
T76444	Protein Kinase C (660-673)
	Protein Kinase C (660-673) (PKC βII (660-673)) 是具有 RACK1结合亲和力的 PKCβII V5 肽。
T6280	Enzastaurin LY317615,恩扎妥林	Apoptosis; PKC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling
	Enzastaurin (LY317615) 是一种PKCβ抑制剂，IC50值为 6 nM。它对 PKCβ 选择性是 PKCα，PKCγ 和 PKCε 的 6-20 倍。
T1606	Fasudil HA-1077,AT877,法舒地尔	ROCK; Serine/threonin kinase; Calcium Channel; PKA; PKC; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
	Fasudil (HA-1077) 是一种非特异性 RhoA/ROCK 抑制剂，也是 Ca2+通道拮抗剂和血管扩张剂。它对蛋白激酶有抑制作用，ROCK1 的 Ki 值为 0.33 μM，ROCK2 和 PKA、PKC、PKG 的 IC50值分别 0.158 μM 和 4.58 μM、12.30 μM、1.650 μM。
T1977	Dorsomorphin Compound C,BML-275	AMPK; Autophagy; TGF-beta/Smad	Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Stem Cells
	Dorsomorphin (BML-275) 是一种 AMPK 抑制剂 (Ki=109 nM)，具有选择性和 ATP 竞争性。Dorsomorphin 可以抑制 BMP I 型受体 ALK2、ALK3 和 ALK6。Dorsomorphin 可诱导自噬，具有抗肿瘤活性。
T7604	Valrubicin Valstar,AD-32,戊柔比星	Antibiotic; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology
	Valrubicin (AD-32) 是一种具有抗炎和抗肿瘤作用的化疗剂，能够抑制 TPA 和 PDBu 诱导的 PKC 活化，IC50值分别为 0.85 和 1.25 μM。
T76008	Protein Kinase C (19-31) (TFA)
	Protein Kinase C (19-31) TFA 是蛋白激酶 C (PKC)的抑制剂,是由 PKCa (残基 19-31) 伪底物调控域衍生而来，25 位丝氨酸取代野生型丙氨酸作为蛋白激酶 C 底物肽，用于检测蛋白激酶 C 的活性。Protein kinase C (PKC) TFA 通过磷酸化丝氨酸和苏氨酸氨基酸残基上的羟基来调控其它蛋白的功能。
T10549	Bisindolylmaleimide VIII acetate Ro 31-7549 acetate,Bis VIII acetate	Apoptosis; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling
	Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) 是一种选择性蛋白激酶 C 抑制剂。它促进 Fas 介导的细胞凋亡，并抑制 T 细胞介导的自身免疫性疾病。
T76456	Protein Kinase C (19-35) Peptide
	Protein Kinase C (19-35) Peptide 是PKC 假底物抑制剂/区域。Protein Kinase C (19-35) Peptide 阻断PKC 激酶结构域的底物结合位点，使PKC 的细胞质形式失活。
T11740	Delcasertib KAI-9803,BMS-875944	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Delcasertib (KAI-9803) 是一种有效且选择性的 δ-蛋白激酶 C (δPKC) 抑制剂，可改善急性心肌梗死动物模型的缺血再灌注损伤。
T12148	N-Desmethyltamoxifen hydrochloride	Estrogen Receptor/ERR; Endogenous Metabolite; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones; Metabolism
	N-Desmethyltamoxifen hydrochloride 是 Tamoxifen 在人体内主要的三苯氧胺代谢物。它是蛋白激酶 C 抑制剂，也是人体 AML 细胞神经酰胺代谢的有效调节因子，可限制神经酰胺糖基化、水解和鞘氨醇磷酸化。
T2609	Masitinib AB1010,马赛替尼	Apoptosis; FAK; c-Fms; FGFR; Bcr-Abl; PDGFR; Src; c-Kit; Hck	Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Masitinib (AB1010) 是生物口服可利用的选择性 c-Kit 抑制剂 (对于人重组c-Kit，IC50=200 nM)，它还抑制PDGFRα/β(IC50s=540/800 nM)，Lyn(对 LynB 的IC50=510 nM)，Lck，较小程度上抑制FGFR3和FAK。它有抗增殖，促凋亡活性，且毒性低。
T80509	PKC 20-28,myristoylated Myristoylated protein kinase C inhibitor 20-28	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	PKC20-28,myristoylated（Myristoylated protein kinase C inhibitor 20-28）为具细胞渗透性之PKC抑制剂，可抑制AngII所诱导之IKca电流激活，用途涵盖癌症与心血管疾病研究。
T3060	Fasudil hydrochloride Fasudil (HA-1077) HCl,盐酸法舒地尔,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877	ROCK; Serine/threonin kinase; Calcium Channel; HIV Protease; PKA; PKC; Autophagy	Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Proteases/Proteasome; Stem Cells; Tyrosine Kinase/Adaptors
	Fasudil hydrochloride (HA-1077) 是一种非特异性RhoA/ROCK 抑制剂，也抑制蛋白激酶，对 ROCK1、PKA、PKC 和 MLCK 的 Ki 值分别为 0.33 μM、1.0 μM、9.3 μM 和 55 μM。
T6146	Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK; Autophagy; TGF-beta/Smad	Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Stem Cells
	Dorsomorphin dihydrochloride (BML-275 2HCl) 是一种 AMPK 抑制剂 (Ki=109 nM)，具有选择性和 ATP 竞争性。Dorsomorphin dihydrochloride 可以抑制 BMP I 型受体 ALK2、ALK3 和 ALK6。Dorsomorphin dihydrochloride 可诱导自噬，具有抗肿瘤活性。
T6588	Mitoxantrone 米托蒽醌,mitozantrone	Topoisomerase; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair
	Mitoxantrone (mitozantrone) 是一种拓扑异构酶 II (Topo II) 的抑制剂，一种蛋白激酶 C (PKC) 的抑制剂 (IC50=8.5 μM)。Mitoxantrone 具有抗肿瘤活性，可以治疗急性髓系白血病、肝细胞癌、乳腺癌等。
T4185	lavendustin C HDBA,NSC 666251,N-(2,5-二羟基苄基)-5-氨基水杨酸	CaMK; EGFR; Tyrosinase; Src	Angiogenesis; JAK/STAT signaling; Neuroscience; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	lavendustin C (NSC 666251) 是 Ca2+钙调蛋白依赖性激酶 II 抑制剂，IC50为 0.2 µM。它抑制 EGFR 相关酪氨酸激酶和 pp60c-src(+)激酶，IC50分别为 0.012 和 0.5 µM。
T3689	Ruboxistaurin hydrochloride Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride,芦布妥林	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Ruboxistaurin hydrochloride (LY 333531 hydrochloride) 是蛋白激酶 C(PKC) 的同工酶选择性抑制剂，竞争性且可逆地抑制 PKCβI 和 PKCβII，IC50 值分别为 4.7 和 5.9 nM。
T8376	PKCβ inhibitor 1 KUN79359	Apoptosis; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling
	PKCβ inhibitor 1 (KUN79359) 是一种 ATP 竞争性和选择性PKCβ抑制剂，对人 PKCβ1 和 PKCβ2 的IC50分别为 21 和 5 nM。

化合物

Protein Kinase C 19-31 acetate

Cat.No: TP1053L

Synonym: Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate

Target: PKC

Protein Kinase C Peptide Substrate acetate

Cat.No: TP1051L

Synonym: Protein Kinase C Peptide Substrate acetate(120253-69-2 free base)

Target: Others

Protein Kinase C (19-36)

Cat.No: TP1503

Synonym: Protein Kinase C 19-36

Protein Kinase C (19-31)

Cat.No: TP1053

Synonym: Protein Kinase C 19-31,PKC (19-31)

Cat.No: T17148

Target: PKC

Cat.No: T7648

Target: Myosin, PKA, PKC

Afuresertib hydrochloride

Cat.No: T7885

Target: ROCK, Akt, PKC

Protein Kinase C Peptide Substrate

Cat.No: TP1051

Synonym: PRKCE,Peptide Epsilon,PKCε

Cat.No: T1911

Synonym: GSK2110183C,GSK2110183

Target: ROCK, Akt, PKC

Cat.No: T14989

Target: ROCK, GRK, PKC

Cat.No: T12494

Target: PKC

A-3 hydrochloride

Cat.No: T14069

Target: CaMK, Casein Kinase, PKA, PKC

Protein Kinase C (19-31) (TFA)(121545-65-1,free)

Cat.No: TP1052

Synonym: PKC (19-31) (TFA),Protein Kinase C (19-31) (TFA)

Cat.No: T35407

Target: PKC

PKC β pseudosubstrate acetate

Cat.No: TP1955L

Synonym: PKC β pseudosubstrate醋酸盐,Protein kinase C beta pseudosubstrate,PKC beta pseudosubstrate,PKC β pseudosubstrate acetate (172308-76-8 Free base)

Target: PKC

Cat.No: T13314

Target: PKC

Cat.No: T2441

Synonym: TAS 301

Target: PKC

Bisindolylmaleimide IV

Cat.No: T7659

Target: Others, PKC

Cat.No: T26019

Synonym: R-59949,R 59949

Target: Others, PKC

Protein kinase C substrate

Cat.No: T76387

Protein Kinase C γ Peptide

Cat.No: T76419

PKC-iota inhibitor 1

Cat.No: T8764

Target: PKC

Protein Kinase C β Peptide

Cat.No: T76421

Cat.No: T14943

Target: VEGFR, CDK, PKC

Cat.No: T17019

Synonym: NIBR3049

Target: GSK-3, JAK, PKC

Cat.No: TQ0028

Synonym: Compound 991,C991

Target: AMPK

Cat.No: T6515

Synonym: Gö 6976

Target: PKC

Cat.No: T6313

Synonym: Goe 6983

Target: PKC

Protein kinase C α peptide TFA

Cat.No: T76388

Cat.No: T6278

Synonym: 索曲妥林,AEB071

Target: PKC

Cat.No: T5600

Synonym: LXS196

Target: PKC

Protein Kinase C (661-671)

Cat.No: T76422

Protein Kinase C (660-673)

Cat.No: T76444

Cat.No: T6280

Synonym: LY317615,恩扎妥林

Target: Apoptosis, PKC, Autophagy

Cat.No: T1606

Synonym: HA-1077,AT877,法舒地尔

Target: ROCK, Serine/threonin kinase, Calcium Channel, PKA, PKC, Autophagy

Cat.No: T1977

Synonym: Compound C,BML-275

Target: AMPK, Autophagy, TGF-beta/Smad

Cat.No: T7604

Synonym: Valstar,AD-32,戊柔比星

Target: Antibiotic, PKC

Protein Kinase C (19-31) (TFA)

Cat.No: T76008

Bisindolylmaleimide VIII acetate

Cat.No: T10549

Synonym: Ro 31-7549 acetate,Bis VIII acetate

Target: Apoptosis, PKC

Protein Kinase C (19-35) Peptide

Cat.No: T76456

Cat.No: T11740

Synonym: KAI-9803,BMS-875944

Target: PKC

N-Desmethyltamoxifen hydrochloride

Cat.No: T12148

Target: Estrogen Receptor/ERR, Endogenous Metabolite, PKC

Cat.No: T2609

Synonym: AB1010,马赛替尼

Target: Apoptosis, FAK, c-Fms, FGFR, Bcr-Abl, PDGFR, Src, c-Kit, Hck

PKC 20-28,myristoylated

Cat.No: T80509

Synonym: Myristoylated protein kinase C inhibitor 20-28

Target: PKC

Fasudil hydrochloride

Cat.No: T3060

Synonym: Fasudil (HA-1077) HCl,盐酸法舒地尔,HA-1077,Fasudil HCl,HA-1077 hydrochloride,AT-877

Target: ROCK, Serine/threonin kinase, Calcium Channel, HIV Protease, PKA, PKC, Autophagy

Dorsomorphin dihydrochloride

Cat.No: T6146

Synonym: BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

Target: AMPK, Autophagy, TGF-beta/Smad

Cat.No: T6588

Synonym: 米托蒽醌,mitozantrone

Target: Topoisomerase, PKC

Cat.No: T4185

Synonym: HDBA,NSC 666251,N-(2,5-二羟基苄基)-5-氨基水杨酸

Target: CaMK, EGFR, Tyrosinase, Src

Ruboxistaurin hydrochloride

Cat.No: T3689

Synonym: Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride,芦布妥林

Target: PKC

PKCβ inhibitor 1

Cat.No: T8376

Synonym: KUN79359

Target: Apoptosis, PKC

Cat. No.	Product Name	Target	Signaling Pathways
TN1557	Decursinol angelate	ERK; VEGFR; PKC; JNK	Angiogenesis; Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors
	Decursinol angelate 是从朝鲜当归根部分离得到的一种天然产物，是 PKC 激酶的激活剂，有细胞毒性，抗肿瘤和抗炎活性。
T5771	Hypocrellin A	Antibacterial; PKC; Parasite	Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology
	Hypocrellin A 是一种天然的PKC 抑制剂，具有光诱导的抗肿瘤、抗真菌和抗病毒活性，还对 MHC 限制性抗原呈递发挥免疫调节作用。
T2851	Daphnetin 7,8-Dihydroxycoumarin,Daphnetol,瑞香素	EGFR; PKA; PKC; Parasite; Autophagy	Angiogenesis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Daphnetin (7,8-Dihydroxycoumarin) 是从 Genus Daphne 中分离得到的香豆素衍生物，有抗氧化、抗炎、抗疟疾和解热作用，可用于凝血功能障碍、类风湿性关节炎等疾病的相关研究。
T4S1335	Daphnoretin Dephnoretin,西瑞香素,Thymelol	Influenza Virus; Caspase; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome
	Daphnoretin (Thymelol) 是从了哥王中提取得到的一种天然产物，具有抗癌和抗病毒活性。它通过在 G2/M 期连续阻断细胞并激活 caspase-3 通路导致 HOS 细胞死亡。
T2750	Ginkgolide C 银杏内酯C,BN-52022	MMP; Sirtuin; Endogenous Metabolite; AMPK	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Ginkgolide C (BN-52022) 是从银杏叶中分离到的一种黄酮类天然产物，可增强体内大鼠的心脏功能，具有减少血小板聚集，改善阿尔兹海默症等作用。
T5S2017	Ingenol (-)-Ingenol,巨大戟二萜醇,巨大戟醇	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Ingenol ((-)-Ingenol) 是一种PKC 激活剂，Ki 值为 30 μM，具有抗肿瘤活性。从 Ingenol 酯中配制新的衍生物可能是开发新的先导化合物以重新激活潜伏 HIV 的创新方法。Ingenol mebutate 是治疗光化性角化病的有效方法。
TN1499	Cimiracemoside C 千层纸素A-7-0-Β-D-葡萄糖醛酸苷,Cimicifugoside M	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Cimiracemoside C (Cimicifugoside M) 是在升麻中发现的一种天然产物，可激活 AMPK 并具有抗糖尿病的潜在活性。
T6S0052	Chelerythrine Toddalin,Broussonpapyrine,白屈菜红碱,Cheleritrine	Apoptosis; BCL; PKC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling
	Chelerythrine (Broussonpapyrine) 是一种天然生物碱，为有效、选择性的 Ca2+/磷脂依赖性PKC 拮抗剂，IC50值为 0.7 μM。它具有抗肿瘤、抗糖尿病、抗炎的活性。它抑制BclXL-Bak BH3肽结合，IC50为 1.5 μM，并从 BclXL 取代了 Bax。它诱导细胞凋亡和自噬。
TN1299	Desmethylglycitein 4',6,7-三羟基异黄酮,4',6,7-三羟异黄酮,6-羟基大豆苷元,6,7,4'-Trihydroxyisoflavone	PI3K; CDK; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) 是大豆中苷元的代谢产物，具有抗氧化性和抗癌活性。它是蛋白激酶 C(PKC)α 的直接抑制剂，抑制正常人皮肤成纤维细胞中的太阳紫外线诱导的基质金属蛋白酶1。它在体内直接结合CDK1和CDK2，抑制 CDK1 和 CDK2 活性。
T13265	Urolithin B 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮	ERK; NF-κB; Akt; Endogenous Metabolite; JNK; AMPK	Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Urolithin B 是一种 ellagitannins 的肠道微生物代谢产物，具有抗炎和抗氧化作用。它也是骨骼肌质量的调节因子，通过减少 IκBα 的磷酸化和降解来抑制 NF-κB 活性，并抑制 JNK、ERK 和 Akt 的磷酸化，并增强 AMPK 的磷酸化。
T3419	Chelerythrine chloride 白屈菜红碱,盐酸白屈菜红碱	Apoptosis; BCL; PKC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling
	Chelerythrine chloride 是一种可渗透细胞的蛋白激酶 C 抑制剂，对磷酸盐受体具有竞争性，而对 ATP 是非竞争性的。它诱导细胞凋亡和自噬。
T5552	Methyl cinnamate	Tyrosinase; Antibacterial; AMPK	Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Methyl cinnamate 是花椒的有效成分，也是一种天然香料。它是一种防止食品褐变的酪氨酸酶抑制剂，具有抗菌活性。它通过由 CaMKK2-AMPK 信号途径介导的机制具有抗脂活性。
T22464	1,2-Dimyristoyl-sn-glycerol 1,2-DMG,1,2-二肉豆蔻酸甘油酯	Others; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Others
	1,2-Dimyristoyl-sn-glycerol (1,2-DMG) 是饱和二酰甘油的一种，可作为激活 PKC 的弱活性第二信使。
T3001	Honokiol 和厚朴酚,NSC 293100	ERK; HCV Protease; MEK; Akt; Autophagy	Autophagy; Cytoskeletal Signaling; MAPK; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Honokiol (NSC-293100) 是厚朴提取物的活性成分，靶向多种信号分子，具有抗氧化，抗炎，抗血管生成和抗癌活性。它可抑制 Akt 的激活并增强 ERK1/ERK2 的磷酸化。
TQ0198	Phorbol 12-myristate 13-acetate 佛波醇12-十四酸酯13-乙酸酯,PMA	S1P Receptor; PKC; NF-κB	Chromatin/Epigenetic; Cytoskeletal Signaling; GPCR/G Protein; NF-κB
	Phorbol 12-myristate 13-acetate (PMA) 属于佛波酯类天然产物，是一种 PKC、SphK、NF-κB 的激活剂。Phorbol 12-myristate 13-acetate 可诱导 THP1 细胞分化。
T6680	Staurosporine Antibiotic AM-2282,星形孢菌素,AM-2282,CGP 41251,星孢菌素	Apoptosis; PKA; Antibacterial; Antibiotic; Src; PKC; Antifungal	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Staurosporine (AM-2282) 是一种蛋白激酶抑制剂，对 PKC、PKA、c-Fgr、Phosphorylase kinase 和 TAOK2 均有抑制活性 (IC50=6/15/2/3/3000 nM)，具有 ATP 竞争性和非选择性。Staurosporine 也可以诱导凋亡。
TN1136	Procyanidin A1 原花青素 A1,Proanthocyanidin A1,原花色素A1	LDL; Calcium Channel; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism
	Procyanidin A1 (Proanthocyanidin A1) 是一种原花青素二聚体，具有抗过敏作用，可抑制蛋白激酶 C 激活下游脱粒或 RBL-213 细胞内部储存的 Ca2+流入。
T3375	Verbascoside 毛蕊花苷,麦角甾苷,Kusaginin,Acteoside,TJC160	Apoptosis; PARP; Antibacterial; PKC; p53; HSV	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Microbiology/Virology
	Verbascoside (Kusaginin) 是从Lantana camara 中得到的糖苷类物质，是具有ATP 竞争性的PKC 抑制剂，IC50值为 25 µM，它还有抗炎，抗肿瘤，抗神经性疼痛等作用。
T3S1416	Decursin Decursinol angelate,前胡素,(+)-Decursin,紫花前胡素	Apoptosis; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling
	Decursin (Decursinol angelate) 是一种细胞毒性剂，是一种来自朝鲜当归根的有效蛋白激酶 C 激活剂。它通过 Hippo/YAP 信号通路抑制 HepG2 细胞的生长。它通过下调 CXCR7 表达来抑制胃癌中的肿瘤生长，迁移和侵袭。
T7792	Hispidin 6-[(1E)-2-(3,4-二羟基苯基)乙烯基]-4-羟基-2H-吡喃-2-酮	Endogenous Metabolite; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
	Hispidin 是来自裂蹄木层孔菌的酚类天然产物，是一种 PKC 抑制剂，具有很强的抗氧化、抗癌、抗糖尿病和抗痴呆作用。
T0392	Artemisinin Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,青蒿素,Artemisinine	HCV Protease; Ferroptosis; Akt; Parasite	Apoptosis; Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Artemisinin (Qinghaosu) 是一种倍半萜烯内酯，是从青蒿植物的地上部分分离的一种抗疟疾药物。它有神经保护和抗癌作用。
T5891	D-ERYTHRO-SPHINGOSINE trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine,鞘氨醇,D-鞘氨醇	Phosphatase; Endogenous Metabolite; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
	D-erythro-Sphingosine (trans-4-Sphingenine) 是一种非常有效的p32激酶活化剂，EC50为 8 μM。它也是一种PP2A 激活剂，抑制蛋白激酶 C (PKC)。
T9605	Sangivamycin BA-90912,桑霉素,NSC 65346	Nucleoside Antimetabolite/Analog; PKC	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair
	Sangivamycin (NSC-65346) 是蛋白激酶 C (PKC) 的有效抑制剂 (Ki = 10 μM)。 Sangivamycin 对多种人类癌症细胞具有抗增殖活性。
T11665	Ionomycin calcium SQ23377 calcium,罗红霉素钙盐(链霉菌属载体)	Apoptosis; Calcium Channel; Antibacterial; Antibiotic; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Ionomycin calcium (SQ23377 calcium) 是选择性钙离子载体，也是一种由 Streptomyces conglobatus 产生的抗生素。它对二价阳离子具有高度特异性，还诱导蛋白激酶 C 激活。Ionomycin 促进细胞凋亡。
T16791	Rottlerin Mallotoxin,NSC 56346,粗糠柴苦素,NSC 94525	CaMK; Apoptosis; Others; HIV Protease; PKA; PKC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Neuroscience; Others; Proteases/Proteasome; Tyrosine Kinase/Adaptors
	Rottlerin (NSC-56346) 是一种从Mallotus Philippinensis 中得到的天然产物，是 PKC 的特异性抑制剂，抑制HIV-1整合和狂犬病病毒感染。它通过活化 caspase 3 诱导细胞凋亡.
T6S0923	Hypericin Hypericine,金丝桃素,Cyclosan	Apoptosis; Antiviral; Influenza Virus; Tyrosine Kinases; Antibacterial; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Hypericin (Cyclosan) 是贯叶连翘的提取物，有抗菌、抗病毒、抗肿瘤和抗抑郁作用。
T5736	1,3-Dicaffeoylquinic acid CYNARIN,1,3-二咖啡酰奎宁酸,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid	Reactive Oxygen Species; Akt; PI3K	Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	1,3-Dicaffeoylquinic acid (CYNARIN) 是一种咖啡酰奎宁酸衍生物，具有抗氧化、自由基清除作用。
TN1033	Sennidin A	HCV Protease; transporter; Akt; PI3K	Cytoskeletal Signaling; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Sennidin A 是从狭叶番泻分离得到的一种天然产物，能够抑制 HCV NS3 解旋酶，其 IC50值为0.8 μM。它诱导 Akt 和葡萄糖转运蛋白4的磷酸化，刺激葡萄糖掺入。
TN1034	Sennidin B	HCV Protease; transporter; Akt; PI3K	Cytoskeletal Signaling; Metabolism; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Sennidin B 是从Cassia angustifolia 分离得到的Sennidin A 异构体，它刺激葡萄糖掺入，诱导Akt 和葡萄糖转运蛋白4 的磷酸化。
T3892	Isoacteoside 异麦角甾苷,Isoverbascoside	NF-κB	NF-κB
	Isoacteoside 具有抗炎作用，通过作用于 caspase-1、丝裂原活化蛋白激酶（c-Jun N-末端激酶、p38、细胞外信号调节蛋白激酶）和核因子-kappa B 途径介导。
T3908	10-Gingerol 10-姜酚	Apoptosis	Apoptosis
	10-Gingerol 是一种姜根脂的主要刺激性成分，具有抗炎、抗氧化和抗增殖作用，能够抑制 MDA-MB-231 肿瘤细胞的增殖(IC50:12.1 μM)。
T4037	Phorbol 4β-Phorbol,佛波醇,(+)-Phorbol	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Phorbol (4β-Phorbol) 是具有毒性的二萜类化合物，其酯类具有强大的生物活性。
T5239	Cholesteryl sulfate sodium Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate	Endogenous Metabolite; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
	Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) 是内源性代谢产物的一种。
TWS1977	Kamebakaurin 尾叶香茶菜丙素,Kamebakaurine	NF-κB	NF-κB
	Kamebakaurin (Kamebakaurine) 是一种提取自Isodon japonicus 中的天然产物，是一种NF-κB 的抑制剂，能够抑制 p50 的 DNA 结合活性。
T6S1418	Praeruptorin C	Antioxidant; Calcium Channel	Membrane transporter/Ion channel; Metabolism; oxidation-reduction
	Praeruptorin C 是白花前胡中的一种主要成分，是钙拮抗剂，pD2′值为 5.7。
TN1448	(-)-Bornyl acetate L-(-)-Bornyl acetate,左旋乙酸冰片酯,Bornyl acetate,(-)-乙酸龙脑酯	p38 MAPK; NF-κB; JNK; Antifungal	MAPK; Microbiology/Virology; NF-κB
	(-)-Bornyl acetate (L-(-)-Bornyl acetate) 是存在于牛膝草油中的一种具有抗真菌活性的 (+)-Bornyl acetate 低活性异构体。
T7285	Ionomycin	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Ionomycin 是一种钙离子载体和一种结合钙离子(Ca2+)的抗生素。它是由联合链霉菌(Streptomyces conglobatus)产生的。它在研究中用于提高细胞内钙水平(Ca2+)，并作为了解 Ca2+跨生物膜运输的研究工具。Ionomycin 可促进细胞凋亡，诱导蛋白激酶 C (PKC)活化。
T3889	Platycodin D	Prostaglandin Receptor; AMPK	Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; PI3K/Akt/mTOR signaling
	Platycodin D 是从桔梗中分离得到的一种皂苷类天然产物，是AMPKα的激活剂，具有抗肥胖活性。它可刺激 TNF-α 合成或抑制 TNF-α mRNA 的降解。
T6S1597	Mulberroside A 桑皮苷 A,桑皮苷A	TNF; Tyrosinase; Interleukin	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Mulberroside A 是桑中的一种主要活性成分，可降低TNF-α、IL-1β和IL-6的表达，抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化。它抑制蘑菇酪氨酸酶，具有抗炎和抗细胞凋亡作用。
T6S1369	Vitexin 牡荆素,Apigenin-8-C-glucoside	Antioxidant	oxidation-reduction
	Vitexin 是一种存在于多种药用植物（如榕树、螺旋藻）中的 c-糖基化的黄酮。它具有广泛的药理作用，包括抗氧化，抗癌，抗炎，抗痛觉过敏和神经保护作用。
T3877	Esculentoside A	NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Esculentoside A 是一种三萜皂苷，从商陆根部分离得到。它在具有抗炎活性，对环氧合酶-2 具有选择性抑制活性。它通过抑制NF-κB 和丝裂原活化蛋白激酶信号通路抑制 LPS 诱导的急性肺损伤中的炎症反应。
T23772	Balanol Ophiocordin,BA1,Azepinostatin,(-)-Balanol,(3R-trans)-Balanol	Others	Others
	Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.
T22723	Dihydrosphingosine	Others	Others
	Dihydrosphingosine is a Protein kinase C inhibitor.
T17198	UCN-02 7-epi-Hydroxystaurosporine	Others	Others
	UCN-02 is a selective protein kinase C inhibitor produced by Streptomyces strain N-12 (IC50s: 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively).
T75565	Vanicoside A	Others	Others
	Vanicoside A 是一种来自Polygonum pensylvanicum 的蛋白激酶 C (PKC)抑制剂。
TN4986	Selinidin	IκB/IKK; p38 MAPK; TNF	Apoptosis; MAPK; NF-κB
	Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.
T16726	Rebeccamycin	Topoisomerase; ADC Cytotoxin	Antibody-drug Conjugate/ADC Related; DNA Damage/DNA Repair
	Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.
TN3711	Corylifol C	ERK; EGFR; p38 MAPK; MEK	Angiogenesis; JAK/STAT signaling; MAPK; Tyrosine Kinase/Adaptors
	Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6) μg/ml, respectively).
T21441	Prostratin 12-Deoxyphorbol-13-acetate	Others	Others
	Prostratin, a protein kinase C activator, has been shown to exhibit promising therapeutic potential against other diseases such as cancer and Alzheimer's disease. Prostratin has the potential to be useful in the treatment of HIV as it could flush viral re
T68802	Vibsanin A	Others	Others
	Vibsanin A，作为一种蛋白激酶C (PKC) 激活剂，展现出对人类癌细胞系的抗增殖活性，同时也兼具HSP90抑制剂的功能。
------------------------ 更多 ------------------------

天然产物

Decursinol angelate

Cat.No: TN1557

Target: ERK, VEGFR, PKC, JNK

Cat.No: T5771

Target: Antibacterial, PKC, Parasite

Cat.No: T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol,瑞香素

Target: EGFR, PKA, PKC, Parasite, Autophagy

Cat.No: T4S1335

Synonym: Dephnoretin,西瑞香素,Thymelol

Target: Influenza Virus, Caspase, PKC

Cat.No: T2750

Synonym: 银杏内酯C,BN-52022

Target: MMP, Sirtuin, Endogenous Metabolite, AMPK

Cat.No: T5S2017

Synonym: (-)-Ingenol,巨大戟二萜醇,巨大戟醇

Target: PKC

Cimiracemoside C

Cat.No: TN1499

Synonym: 千层纸素A-7-0-Β-D-葡萄糖醛酸苷,Cimicifugoside M

Target: AMPK

Cat.No: T6S0052

Synonym: Toddalin,Broussonpapyrine,白屈菜红碱,Cheleritrine

Target: Apoptosis, BCL, PKC, Autophagy

Desmethylglycitein

Cat.No: TN1299

Synonym: 4',6,7-三羟基异黄酮,4',6,7-三羟异黄酮,6-羟基大豆苷元,6,7,4'-Trihydroxyisoflavone

Target: PI3K, CDK, PKC

Cat.No: T13265

Synonym: 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Chelerythrine chloride

Cat.No: T3419

Synonym: 白屈菜红碱,盐酸白屈菜红碱

Target: Apoptosis, BCL, PKC, Autophagy

Methyl cinnamate

Cat.No: T5552

Target: Tyrosinase, Antibacterial, AMPK

1,2-Dimyristoyl-sn-glycerol

Cat.No: T22464

Synonym: 1,2-DMG,1,2-二肉豆蔻酸甘油酯

Target: Others, PKC

Cat.No: T3001

Synonym: 和厚朴酚,NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Phorbol 12-myristate 13-acetate

Cat.No: TQ0198

Synonym: 佛波醇12-十四酸酯13-乙酸酯,PMA

Target: S1P Receptor, PKC, NF-κB

Cat.No: T6680

Synonym: Antibiotic AM-2282,星形孢菌素,AM-2282,CGP 41251,星孢菌素

Target: Apoptosis, PKA, Antibacterial, Antibiotic, Src, PKC, Antifungal

Cat.No: TN1136

Synonym: 原花青素 A1,Proanthocyanidin A1,原花色素A1

Target: LDL, Calcium Channel, PKC

Cat.No: T3375

Synonym: 毛蕊花苷,麦角甾苷,Kusaginin,Acteoside,TJC160

Target: Apoptosis, PARP, Antibacterial, PKC, p53, HSV

Cat.No: T3S1416

Synonym: Decursinol angelate,前胡素,(+)-Decursin,紫花前胡素

Target: Apoptosis, PKC

Cat.No: T7792

Synonym: 6-[(1E)-2-(3,4-二羟基苯基)乙烯基]-4-羟基-2H-吡喃-2-酮

Target: Endogenous Metabolite, PKC

Cat.No: T0392

Synonym: Qinghaosu,Artemisinine,Qinghaosu,NSC 369397,青蒿素,Artemisinine

Target: HCV Protease, Ferroptosis, Akt, Parasite

D-ERYTHRO-SPHINGOSINE

Cat.No: T5891

Synonym: trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine,鞘氨醇,D-鞘氨醇

Target: Phosphatase, Endogenous Metabolite, PKC

Cat.No: T9605

Synonym: BA-90912,桑霉素,NSC 65346

Target: Nucleoside Antimetabolite/Analog, PKC

Ionomycin calcium

Cat.No: T11665

Synonym: SQ23377 calcium,罗红霉素钙盐(链霉菌属载体)

Target: Apoptosis, Calcium Channel, Antibacterial, Antibiotic, PKC

Cat.No: T16791

Synonym: Mallotoxin,NSC 56346,粗糠柴苦素,NSC 94525

Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy

Cat.No: T6S0923

Synonym: Hypericine,金丝桃素,Cyclosan

Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC

1,3-Dicaffeoylquinic acid

Cat.No: T5736

Synonym: CYNARIN,1,3-二咖啡酰奎宁酸,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid

Target: Reactive Oxygen Species, Akt, PI3K

Cat.No: TN1033

Target: HCV Protease, transporter, Akt, PI3K

Cat.No: TN1034

Target: HCV Protease, transporter, Akt, PI3K

Cat.No: T3892

Synonym: 异麦角甾苷,Isoverbascoside

Target: NF-κB

Cat.No: T3908

Synonym: 10-姜酚

Target: Apoptosis

Cat.No: T4037

Synonym: 4β-Phorbol,佛波醇,(+)-Phorbol

Target: PKC

Cholesteryl sulfate sodium

Cat.No: T5239

Synonym: Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate

Target: Endogenous Metabolite, PKC

Cat.No: TWS1977

Synonym: 尾叶香茶菜丙素,Kamebakaurine

Target: NF-κB

Cat.No: T6S1418

Target: Antioxidant, Calcium Channel

(-)-Bornyl acetate

Cat.No: TN1448

Synonym: L-(-)-Bornyl acetate,左旋乙酸冰片酯,Bornyl acetate,(-)-乙酸龙脑酯

Target: p38 MAPK, NF-κB, JNK, Antifungal

Cat.No: T7285

Target: Calcium Channel

Cat.No: T3889

Target: Prostaglandin Receptor, AMPK

Cat.No: T6S1597

Synonym: 桑皮苷 A,桑皮苷A

Target: TNF, Tyrosinase, Interleukin

Cat.No: T6S1369

Synonym: 牡荆素,Apigenin-8-C-glucoside

Target: Antioxidant

Esculentoside A

Cat.No: T3877

Target: NF-κB, COX

Cat.No: T23772

Synonym: Ophiocordin,BA1,Azepinostatin,(-)-Balanol,(3R-trans)-Balanol

Target: Others

Dihydrosphingosine

Cat.No: T22723

Target: Others

Cat.No: T17198

Synonym: 7-epi-Hydroxystaurosporine

Target: Others

Cat.No: T75565

Target: Others

Cat.No: TN4986

Target: IκB/IKK, p38 MAPK, TNF

Cat.No: T16726

Target: Topoisomerase, ADC Cytotoxin

Cat.No: TN3711

Target: ERK, EGFR, p38 MAPK, MEK

Cat.No: T21441

Synonym: 12-Deoxyphorbol-13-acetate

Target: Others

Cat.No: T68802

Target: Others

--------- 更多 ---------

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02090	PKN1 Protein, Human, Recombinant (His) Protein kinase C-like 1,Protease-...	Human	E. coli
	PKN1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.5 kDa and the accession number is Q16512.
TMPY-04455	PKC iota Protein, Human, Recombinant (GST) PKCI,nPKC-iota,protein kinase...	Human	Baculovirus Insect Cells
	Protein kinase C iota type, also known as Atypical protein kinase C-lambda/iota, aPKC-lambda/iota and PRKCI, is a cytoplasm, membrane and nucleus protein which belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and PKC subfamily. PRKCI contains one AGC-kinase C-terminal domain, one OPR domain, one phorbol-ester/DAG-type zinc finger and one protein kinase domain. PRKCI is predominantly expressed in lung and brain, but also expressed at lower levels in many tissues includ...
TMPJ-01074	PKCE Protein, Human, Recombinant (His) PRKCE,PKCE,nPKC-ε,nPKC-E...	Human	E. coli
	Protein Kinase C Epsilon type is a member of the serine- and threonine-specific protein kinase family that can be activated by calcium and the second messenger diacylglycerol. Protein Kinase C Epsilon contains these domains: one AGC-kinase C-terminal domain, one C2 domain, one protein kinase domain and two phorbol-ester/DAG-type zinc fingers. Protein Kinase C Epsilon phosphorylate a variety of protein targets and has been identified to participate in diverse cellular signaling pathways. It has m...
TMPJ-01387	PACSIN2 Protein, Human, Recombinant (His) Protein Kinase C and Cas...	Human	HEK293 Cells
	Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2 (PACSIN2) is a member of the PACSIN family. PACSIN2 is localized to the plasma membrane via its coiled-coil domain. PACSIN2 is widely expressed and contains one FCH domain and one SH3 domain. PACSIN2 forms homo- and hetero-aggregates with other PACSINs. PACSIN2 may play a role in vesicle formation and transport. In addition, PACSIN2 is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymeri...
TMPH-01938	PRKCD Protein, Human, Recombinant (His) Tyrosine-protein kinase PRKCD,PRK...	Human	E. coli
	PRKCD Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-01143	MERTK/Mer Protein, Human, Recombinant (aa 1-323, His) MER,Receptor tyrosine kinase MerTK,Tyrosin...	Human	HEK293 Cells
	Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. It can’t be expressed in normal B- and T-lymphocytes, but it is usually expressed in numerous neoplastic B- and T-cell lines. MERTK could regulate many physiological processes, such as cell survival, migration, differentiation. It was demonstrated that t...
TMPJ-01307	PACSIN1 Protein, Human, Recombinant (His) Protein Kinase C and Cas...	Human	HEK293 Cells
	Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 (PACSIN1) belongs to the PACSIN family. PACSIN1 contains one FCH domain and one SH3 domain. PACSIN1 is highly expressed in the brain and at lower leves in the heart, pancreas, and liver. PACSIN1 may play a role in vesicle formation and transport. PACSIN1 has been shown to interact with DNM1, PACSIN3, Huntingtin, and PACSIN2. In addition, PACSIN1 is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).
TMPH-02275	Lck Protein, Human, Recombinant (His) Proto-oncogene Lck,T cell-spe...	Human	E. coli
	Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules...
TMPY-04389	MAP3K8 Protein, Human, Recombinant (GST) TPL2,MEKK8,EST,ESTF,COT,Tpl-2,c-C...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase kinase kinase 8, also known as Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2 and MAP3K8, is a cytoplasm protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase kinase subfamily. MAP3K8 is expressed in several normal tissues and human tumor-derived cell lines. Isoform 1 of MAP3K8 is activated specifically during the S and G2/M phases of the...
TMPH-02472	14-3-3 beta/alpha Protein, Mouse, Recombinant (His) Ywhab,Protein kinase C inhibitor ...	Mouse	P. pastoris (Yeast)
	14-3-3 beta/alpha Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 30.1 kDa and the accession number is Q9CQV8.
TMPH-02471	14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His) 14-3-3 protein beta/alpha,Protein kina...	Mouse	E. coli
	14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 33.6 kDa and the accession number is Q9CQV8.
TMPH-02473	14-3-3 zeta/delta Protein, Mouse, Recombinant (His & SUMO) Ywhaz,14-3-3 protein zeta/delta,SEZ-2,KCIP...	Mouse	E. coli
	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation. In neurons, regulates spine maturation through the modulation of ARHGEF7 activity. 14-3-3 zeta/delta Prot...
TMPJ-00648	EGFR vIII Protein, Human, Recombinant (His) EGFR,Proto-oncogene c-ErbB-1,Epidermal gro...	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 61-75 Kda and the accession number is NP_001333870.
TMPJ-01382	HSPB8 Protein, Human, Recombinant (His) Small stress protein-like protein HSP22,	Human	E. coli
	Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity，appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have bee...
TMPJ-00647	EGFR vIII Protein, Human, Recombinant (hFc) EGFR,Epidermal growth factor receptor,Prot...	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is NP_001333870.
TMPJ-00646	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated Epidermal growth factor receptor,EGFR,Prot...	Human	HEK293 Cells
	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is NP_001333870.
TMPH-01801	NME2 Protein, Human, Recombinant (His & Myc) NME2,nm23-H2,Histidine protein kinase NDKB...	Human	E. coli
	NME2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.2 kDa and the accession number is P22392.
TMPH-01977	Src Protein, Human, Recombinant (His) Proto-oncogene c-Src,Proto-on...	Human	E. coli
	Src Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00413	HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated Proto-oncogene-like protein c-Erb...	Human	HEK293 Cells
	HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 90-120 KDa and the accession number is P21860.
TMPH-01995	RAF1 Protein, Human, Recombinant (His & SUMO) RAF1,Raf-1,Proto-oncogene c-RAF,RAF proto-...	Human	E. coli
	RAF1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 89.1 kDa and the accession number is P04049.
TMPJ-00899	HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) HER3,Proto-oncogene-like protein c	Human	HEK293 Cells
	HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3.
TMPJ-00402	CD117 Protein, Human, Recombinant (hFc) KIT,CD117,v-kit Hardy-Zuckerman 4 feline s...	Human	HEK293 Cells
	C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily and CSF-1/PDGF receptor subfamily. SCF R expression on mast cells enables them to infiltrate SCF-secreting tumors where they promote tumor growth and induce local immune suppression. SCF R is up-regulated on dendritic cells by Th2-orTh17-biasing sti...
TMPJ-00791	HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His) p185erbB2,Epidermal growth factor receptor...	Rat	E. coli
	ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB...
TMPJ-00415	HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated SF receptor,HGF receptor,Scatter ...	Human	HEK293 Cells
	Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which undergoes cotranslational proteolytic cleavage. Mature HGF R is a disulfide-linked dimer composed of a 50 kDa extracellular α chain and a 145 kDa transmembrane β chain. Proteolysis and alternate splicing generate additional forms of human HGF R which either lack of the kinase domai...
TMPJ-01261	PPP1R14A Protein, Human, Recombinant (His) 17 kDa PKC-Potentiated Inhibitory Protein ...	Human	E. coli
	Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase. PPP1R14A is the inhibitor of PPP1CA. When phosphorylated, PPP1R14A has over 1000-fold higher inhibitory activity, creating a molecular switch for regulating the phosphorylation status of PPP1CA su...
TMPY-04571	ERK2 Protein, Mouse, Recombinant (His & GST) PRKM2,C78273,mitogen-activated protein...	Mouse	Baculovirus Insect Cells
	ERK2 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.1 kDa and the accession number is P63085.
TMPH-03364	RBCK1 Protein, Rat, Recombinant (His & Myc) Heme-oxidized IRP2 ubiquitin ligase 1 homolog,RING-type E3 u...	Rat	E. coli
	RBCK1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 65.1 kDa and the accession number is Q62921.
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST) MKK4,MEK4,PRKMK4,Sek1,JNKK1,Serk1,mitogen-activated...	Mouse	Baculovirus Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is a protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K4 / JNKK1 is a protein kinase that is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. MAP2K4 / ...
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST) v-abl,ABL,JTK7,ABL proto-oncogene 1, non-rec	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-02028	RON/CD136 Protein, Human, Recombinant (His) CD136,macrophage stimulating 1 rec	Human	HEK293 Cells
	The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. As the tyrosine kinase receptor is comprised of an extracellular domain, MST1R protein contains the ligand-binding pocket and an intracellular region where the kinase domain is located. MST1R signaling may be involved in the regulation of macrophage and T-lymphocyte activation in...
TMPJ-00375	HGF Protein, Human, Recombinant (His) Scatter factor,Hepatocyte growth ...	Human	HEK293 Cells
	HGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases and contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelia...
TMPY-02543	PCNA Protein, Human, Recombinant (His) ATLD2,proliferating cell nuclear antigen	Human	Baculovirus Insect Cells
	Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replic...
TMPH-03764	YAP1 Protein, Human, Recombinant (His) YAP1-2gamma,YAP2L,YAP65	Human	P. pastoris (Yeast)
	Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1,...
TMPY-02219	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) NS1 Protein	H1N1	E. coli
	The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the NS2 protein, which mediates the export of vRNPs. The non-structural (NS1) protein is found in Influenzavirus A, Influenzavirus B, and Influenzavirus C. The non-structural (NS1) protein of the highly pathogenic avian H5N1 viruses circulating in poultry and waterfowl in Southeast As...
TMPH-02271	BTK Protein, Human, Recombinant (His) BPK,AGMX1,ATK,B-cell progenitor kinase,Tyr...	Human	Baculovirus Insect Cells
	Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in...
TMPY-04411	YES1 Protein, Human, Recombinant (His & GST) HsT441,c-yes,YES proto-oncogene 1, Src...	Human	Baculovirus Insect Cells
	Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 / c-Yes contains one protein kinase domain, one SH2 domain and one SH3 domain. It is thought that the subcellular distribution of Src-family tyrosine kinases, including c-Yes binding to the cellular membrane, is membranous and/or cytoplasmic. YES1 / c-Yes protein tyrosine kinase i...
TMPY-02761	Rack1 Protein, Human, Recombinant (His & MBP) PIG21,Gnb2-rs1,H12.3,RACK1,HLC-7	Human	E. coli
	The scaffolding protein, Rack1, is a seven-WD-domain-containing protein that has been implicated in binding to integrin beta subunit cytoplasmic domains and to members of two kinase families (src and protein kinase C, PKC) that mediate integrin bidirectional signaling.Rack1 may link protein kinase C directly to integrins and participate in the regulation of integrin functions.Rack1 regulates the localization of an essential PCP protein and acts as a molecular switch to promote PCP signaling.
TMPK-00457	HGFR/c-Met Protein, Human, Recombinant (His & Avi) cMET,Met (c-Met),MET,HGF/SF recep...	Human	HEK293 Cells
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. HGFR/c-Met ...
TMPK-00499	HGFR/c-Met Protein, Cynomolgus, Recombinant (His) MET,oncogene MET,cMET,SF receptor...	Cynomolgus	HEK293 Cells
	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein possesses tyrosine kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. HGFR/c-Met ...
TMPH-00713	Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc) Polyphosphoric acid kinase,ATP-po...	E. coli	E. coli
	Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 87.7 kDa and the accession number is P0A7B1.
TMPH-01251	DUSP26 Protein, Human, Recombinant (His & SUMO) MKP-8,NATA1,DSP-4,SKRP3,DUSP26,MKP8,LDP-4,LDP4,DUSP24,Dual s...	Human	E. coli
	Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
TMPY-04561	SGK3 Protein, Human, Recombinant (His & GST) serum/glucocorticoid regulated	Human	Baculovirus Insect Cells
	Serine / threonine-protein kinase Sgk3, also known as Serum / glucocorticoid-regulated kinase 3, Serum / glucocorticoid-regulated kinase-like and SGK3, is a cytoplasmic vesicle protein that belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. SGK3 contains one AGC-kinase C-terminal domain, one protein kinase domain and one PX (phox homology) domain. Two specific sites of SGK3, one in the kinase domain (Thr-32) and the other in the C-terminal regulatory region (Ser-486...
TMPY-04456	PKC nu Protein, Human, Recombinant (GST) PRKCN,nPKC-NU,PKC-NU,PKD3,EPK2,	Human	Baculovirus Insect Cells
	Serine/threonine-protein kinase D3, also known as Protein kinase C nu type, Protein kinase EPK2, PRKD3, EPK2 and PRKCN, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD3 / PRKCN contains one PH domain, two phorbol-ester/DAG-type zinc fingers and one protein kinase domain. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second ...
TMPY-04421	FES Protein, Human, Recombinant (His & GST) FPS,FES proto-oncogene, tyrosine kinase	Human	Baculovirus Insect Cells
	Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and oneSH2 domain. FES is a non-receptor protein tyrosine kinase expressed in hematopoietic progenitors and differentiated myeloid cells. FES is observed in the nuclear, granular and plasma membrane fractions of primary human neutrophils and the myeloid leukemia cell line, HL-6. T...
TMPH-00689	Propionate kinase Protein, E. coli O6:H1, Recombinant (His & Myc) tdcD,Propionate kinase	E. coli	E. coli
	Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. Propionate kinase Protein, E. coli O6:H1, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 50.4 kDa and the accession number is P59244.
TMPY-04425	PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST) PRAK,MAPKAP-K5,MK-5,mitogen-activated protein	Human	Baculovirus Insect Cells
	MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK). It is widely distributed. MAPKAPK5 can be phosphorylated by an extracellular-regulated kinase (ERK), and p38 kinase but not by c-jun N-terminal kinase (JNK)in vitro. Recombinant GST-MAPKAPK5 protein can phosphorylate a peptide derived from the regulator...
TMPJ-01112	PRKG1 Protein, Human, Recombinant (His) PRKGR1B,PRKG1B,cGKI,cGMP-Dependent Pro...	Human	HEK293 Cells
	cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one protein kinase domain. PRKG1 is mainly expressed in the lung and placenta. PRKG1 acts as a key mediator of the nitric oxide (NO)/cGMP signaling pathway. PRKG1 can phosphorylate many proteins that regulate platelet activation and adhesion, smooth muscle contraction, cardiac function,...
TMPY-04550	JNK2 Protein, Human, Recombinant (His) JNK2α,SAPK1a,PRKM9,JNK2β,JNK2,SAPK,JNK2BETA,mitogen-ac	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating some transcription factors, such as c-Jun and ATF2. The crystal structure of human JNK2 complexed with an indazole inhibitor by applying a high-throughput protein engineering and surface-site mutagenesis approach. A n...
TMPK-00645	VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His) KRD1,VEGFR2,FLK1,CD309,Ly73,VEGFR,VEGFR-21,KDR	Rhesus	HEK293 Cells
	Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with ...
TMPY-04547	PBK/TOPK Protein, Human, Recombinant (His) HEL164,Nori-3,CT84,TOPK,PDZ binding kinase...	Human	Baculovirus Insect Cells
	PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the characteristic protein kinase subdomains and a C-terminal PDZ-binding T/SXV motif. PBK is expressed in the testis restrictedly expressed in outer cell layer of seminiferous tubules, as well as placenta. PBK may be enrolled in the activation of lymphoid cells and support testicular fun...
------------------------ 更多 ------------------------

重组蛋白

PKN1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02090

Species: Human

Expression System: E. coli

PKC iota Protein, Human, Recombinant (GST)

Cat.No: TMPY-04455

Species: Human

Expression System: Baculovirus Insect Cells

PKCE Protein, Human, Recombinant (His)

Cat.No: TMPJ-01074

Species: Human

Expression System: E. coli

PACSIN2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01387

Species: Human

Expression System: HEK293 Cells

PRKCD Protein, Human, Recombinant (His)

Cat.No: TMPH-01938

Species: Human

Expression System: E. coli

MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)

Cat.No: TMPJ-01143

Species: Human

Expression System: HEK293 Cells

PACSIN1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01307

Species: Human

Expression System: HEK293 Cells

Lck Protein, Human, Recombinant (His)

Cat.No: TMPH-02275

Species: Human

Expression System: E. coli

MAP3K8 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04389

Species: Human

Expression System: Baculovirus Insect Cells

14-3-3 beta/alpha Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02472

Species: Mouse

Expression System: P. pastoris (Yeast)

14-3-3 beta/alpha Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02471

Species: Mouse

Expression System: E. coli

14-3-3 zeta/delta Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02473

Species: Mouse

Expression System: E. coli

EGFR vIII Protein, Human, Recombinant (His)

Cat.No: TMPJ-00648

Species: Human

Expression System: HEK293 Cells

HSPB8 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01382

Species: Human

Expression System: E. coli

EGFR vIII Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00647

Species: Human

Expression System: HEK293 Cells

EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00646

Species: Human

Expression System: HEK293 Cells

NME2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01801

Species: Human

Expression System: E. coli

Src Protein, Human, Recombinant (His)

Cat.No: TMPH-01977

Species: Human

Expression System: E. coli

HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated

Cat.No: TMPJ-00413

Species: Human

Expression System: HEK293 Cells

RAF1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01995

Species: Human

Expression System: E. coli

HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)

Cat.No: TMPJ-00899

Species: Human

Expression System: HEK293 Cells

CD117 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00402

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPJ-00791

Species: Rat

Expression System: E. coli

HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated

Cat.No: TMPJ-00415

Species: Human

Expression System: HEK293 Cells

PPP1R14A Protein, Human, Recombinant (His)

Cat.No: TMPJ-01261

Species: Human

Expression System: E. coli

ERK2 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-04571

Species: Mouse

Expression System: Baculovirus Insect Cells

RBCK1 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03364

Species: Rat

Expression System: E. coli

MKK4 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-04572

Species: Mouse

Expression System: Baculovirus Insect Cells

C-ABL/ABL1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04396

Species: Human

Expression System: Baculovirus Insect Cells

RON/CD136 Protein, Human, Recombinant (His)

Cat.No: TMPY-02028

Species: Human

Expression System: HEK293 Cells

HGF Protein, Human, Recombinant (His)

Cat.No: TMPJ-00375

Species: Human

Expression System: HEK293 Cells

PCNA Protein, Human, Recombinant (His)

Cat.No: TMPY-02543

Species: Human

Expression System: Baculovirus Insect Cells

YAP1 Protein, Human, Recombinant (His)

Cat.No: TMPH-03764

Species: Human

Expression System: P. pastoris (Yeast)

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

Cat.No: TMPY-02219

Species: H1N1

Expression System: E. coli

BTK Protein, Human, Recombinant (His)

Cat.No: TMPH-02271

Species: Human

Expression System: Baculovirus Insect Cells

YES1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04411

Species: Human

Expression System: Baculovirus Insect Cells

Rack1 Protein, Human, Recombinant (His & MBP)

Cat.No: TMPY-02761

Species: Human

Expression System: E. coli

HGFR/c-Met Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00457

Species: Human

Expression System: HEK293 Cells

HGFR/c-Met Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00499

Species: Cynomolgus

Expression System: HEK293 Cells

Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00713

Species: E. coli

Expression System: E. coli

DUSP26 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01251

Species: Human

Expression System: E. coli

SGK3 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04561

Species: Human

Expression System: Baculovirus Insect Cells

PKC nu Protein, Human, Recombinant (GST)

Cat.No: TMPY-04456

Species: Human

Expression System: Baculovirus Insect Cells

FES Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04421

Species: Human

Expression System: Baculovirus Insect Cells

Propionate kinase Protein, E. coli O6:H1, Recombinant (His & Myc)

Cat.No: TMPH-00689

Species: E. coli

Expression System: E. coli

PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04425

Species: Human

Expression System: Baculovirus Insect Cells

PRKG1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01112

Species: Human

Expression System: HEK293 Cells

JNK2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04550

Species: Human

Expression System: Baculovirus Insect Cells

VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00645

Species: Rhesus

Expression System: HEK293 Cells

PBK/TOPK Protein, Human, Recombinant (His)

Cat.No: TMPY-04547

Species: Human

Expression System: Baculovirus Insect Cells

--------- 更多 ---------

Cat. No.	Product Name	Target	Signaling Pathways
T37044	1,2-Dioleoyl-rac-glycerol-13C3 1,2-Dioleoyl-rac-glycerol-13C3
	1,2-Dioleoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2-dioleoyl-rac-glycerol by GC- or LC-MS. 1,2-dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-2 positions. It effectively binds the C1 domain to activate conventional protein kinase C forms and serves as a substrate for diacylglycerol kinases and multisubstrate lipid kinase.1,2,3 \|1. Yamaguchi, Y., Shirai, Y., Matsubara, T., et al. Phosphorylation and up-reg...

同位素标记化合物

1,2-Dioleoyl-rac-glycerol-13C3

Cat.No: T37044

Synonym: 1,2-Dioleoyl-rac-glycerol-13C3

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼