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Search Results for " protein r "

Targets Recommended: Others PKC

106

抑制剂 & 化合物

9

天然产物

4

化合物库

105

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L8710	铜死亡化合物库		400 compounds
	TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物，可以用于铜死亡机制及相关疾病研究
L3510	甲基化化合物库		128 compounds
	128 种甲基化相关的化合物，可以用于高通量和高内涵筛选；
DO2200	共价抑制剂库CD		12000 compounds
	数量多：超过12000种共价结合化合物，并且数量在持续增加；
DO1200	药物靶点库		53200 compounds
	数量多，含53200种小分子化合物，是高通量筛选的有力工具；

化合物库

铜死亡化合物库

Cat.No: L8710

Compounds: 400

甲基化化合物库

Cat.No: L3510

Compounds: 128

共价抑制剂库CD

Cat.No: DO2200

Compounds: 12000

药物靶点库

Cat.No: DO1200

Compounds: 53200

Cat. No.	Product Name	Target	Signaling Pathways
T26019	R59949 R-59949,R 59949	Others; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Others
	R59949 是一种泛二酰甘油激酶(DGK)抑制剂，IC50为 300 nM。它通过提高内源性配体二酰甘油水平来激活蛋白激酶 C(PKC)。它强烈抑制 Ⅰ 型 DGKα 和 γ 的活性，中度减弱 Ⅱ 型 DGKθ 和 κ 的活性。
T10667	Calmidazolium chloride R 24571,钙调蛋白抑制剂	CaMK; Autophagy	Autophagy; Neuroscience
	Calmidazolium chloride (R 24571) 是一种钙调蛋白拮抗剂，对CaM 依赖性磷酸二酯酶和钙调蛋白诱导的红细胞Ca2+转运ATP 酶活化有拮抗作用，IC50分别为0.15和0.35 μM。Calmidazolium chloride 结合CaMK 的Kd 值为3 nM。Calmidazolium chloride 在抗癌领域有研究的价值。
T4207	(S,R,S)-AHPC hydrochloride VHL Ligand 1 hydrochloride,ULM-1,Protein degrader 1 hydrochloride	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC hydrochloride (Protein degrader 1 hydrochloride) 是基于 VH032 的 VHL 配体，可用于募集 von Hippel-Lindau (VHL) 蛋白。它能够利用 linker 与靶蛋白配体连接，得到 PROTAC 分子。
T0351	Risperidone Risperidal,R 64 766,利培酮	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; P-gp	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Risperidone (R 64 766) 是5-HT2受体阻断剂、P-糖蛋白抑制剂和多巴胺 D2受体的拮抗剂，对 5-HT2A 和多巴胺 D2受体的 Ki 值分别为 4.8 和 5.9 nM。
T8476	RSVA405 RSVA 405	AMPK; STAT; Autophagy	Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Stem Cells
	RSVA405 是一种具有口服活性的AMPK 激活剂，EC50值为 1 μM。它也是一种 STAT3 抑制剂，具有抗炎作用，可研究肥胖症。它通过促进 CaMKKβ 依赖的 AMPK 活化，从而抑制mTOR，并促进自噬以增加 Aβ 的降解。
T2614	GSK2606414	Apoptosis; PERK; Autophagy	Apoptosis; Autophagy
	GSK2606414 是可渗透细胞且有口服活性的蛋白激酶 R 样内质网激酶抑制剂，IC50值为 0.4 nM。
T2654	GSK2656157	Apoptosis; PERK; Autophagy	Apoptosis; Autophagy
	GSK2656157 是一种ATP 竞争性的PERK 选择性抑制剂，IC50值为 0.9 nM。
T21976	ONO-8130	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	ONO-8130 是前列腺素 EP1 受体选择性拮抗剂，口服有活力，能够阻断 L6 脊髓中ERK 的磷酸化。它可缓解环磷酰胺致膀胱炎小鼠的膀胱疼痛，可用于研究间质性膀胱炎。
T22436	Takeda-6d	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Takeda-6d 是一种新型、有效的 DFG-out RAF/血管内皮生长因子受体 2 (VEGFR2) 抑制剂，IC50 分别为 7.0 nM 和 2.2 nM。
T6183	ISRIB (trans-isomer) ISRIB,ISRIB trans-isomer,trans-isomer,trans-ISRIB	Apoptosis; PERK; Autophagy	Apoptosis; Autophagy
	ISRIB (trans-isomer) (ISRIB trans-isomer)是一种 PERK 的高效抑制剂，可有效逆转 eIF2α 磷酸化的作用，IC50值为 5 nM。
T1725	Y-27632 dihydrochloride 反式-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐,Y-27632 2HCl	ROCK; Apoptosis	Apoptosis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Stem Cells
	Y-27632 dihydrochloride (Y-27632 2HCl) 是一种 ROCK-I 和 ROCK-II 抑制剂，具有口服有效性、ATP 竞争性。Y-27632 dihydrochloride 还抑制分离诱导的小鼠前列腺干或祖细胞凋亡。
T13671	(S,R,S)-AHPC-Me hydrochloride VHL ligand 2 hydrochloride,E3 ligase Ligand 1	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cells resistant to castration, exhibiting a remarkable DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, (S,R,S)-AHPC-Me hydrochloride serves as the VHL ligand derived from (S,R,S)-AHPC for the recruitment of von Hippel-Lindau (VHL) protein.
T40028	(S,R,S)-AHPC	Ligand for E3 Ligase	PROTAC
	(S,R,S)-AHPC 是一种 VHL 配体，用于募集 VHL 蛋白。
T60657	(R)-STU104	TNF; MAPK	Apoptosis; MAPK
	(R)-STU104 是一种新型 TAK1-MKK3 蛋白-蛋白相互作用（PPI）抑制剂，抑制 TNF-α，通过与 MKK3 结合并破坏TAK1磷酸化MKK3来抑制TAK1/MKK3/p38/MnK1/MK2/elF4E信号通路。(R)-STU104 是治疗溃疡性结肠炎的候选化合物。
T72754L	(R)-JAK2/STAT3-IN-10a	Antiviral	Immunology/Inflammation
	(R)-JAK2/STAT3-IN-10a 是 JAK2/STAT3-IN-1 的R型异构体。JAK2/STAT3-IN-1 是一种 GP130 D1 结构域抑制剂，具有抗肿瘤活性，抑制 JAK2 和 STAT3 磷酸化。(R)-JAK2/STAT3-IN-1 对 GP130 蛋白的 KD 值为3.8μM。
T29061	UNC0006 UNC-0006,UNC 0006	cAMP	GPCR/G Protein
	UNC0006 是 β抑制蛋白偏向 D（2）R 配体，同时也是 G（i）调节的 cAMP 产生的拮抗剂和 D（2）R/β-arrestin-2 相互作用的部分激动剂。UNC0006 具有抗精神病的活性，可用于研究神经系统疾病。
T8412	(S,R,S)-AHPC VH032-NH2,MDK7526,VHL ligand 1	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC (VH032-NH2) 是一种 VH032-based VHL ligand，可用于募集 von Hippel-Lindau (VHL)蛋白。它能够利用 linker 与靶蛋白配体连接，得到 PROTAC 分子。
T8507	MAC-545496	Antibacterial	Microbiology/Virology
	MAC-545496 是一种抗毒剂，可逆转耐甲氧西林的菌株中的 β-内酰胺耐药性。它是糖肽抗性相关蛋白 R 的纳摩尔抑制剂，对全长 GraR 蛋白具有很强的结合亲和力。
T72322	R 59-022 hydrochloride DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride	5-HT Receptor; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; GPCR/G Protein; Neuroscience
	R 59-022 hydrochloride (DKGI-I hydrochloride) 是一种 5-HT Receptor 拮抗剂，可激活蛋白激酶 C (PKC)。R 59-022 hydrochloride 是一种 DGK 抑制剂 (IC50:2.8 µM),可抑制 OAG 磷酸化为 OAPA。R 59-022 增强血小板中凝血酶诱导的甘油二酯的产生，并抑制嗜中性粒细胞中磷脂酸的产生。
T19836	2-Aminopurine	DNA/RNA Synthesis; PKA	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Tyrosine Kinase/Adaptors
	2-Aminopurine 是一种鸟苷和腺苷的荧光类似物，是基于荧光衰变的 DNA 结构探针。当它插入寡核苷酸后，其荧光会通过与天然碱基堆积而被高度淬灭。它可用于核酸的结构和动力学的探测。
T17927	(S,R,S)-AHPC TFA VH032-NH2 TFA,VHL ligand 1 TFA	Others; Ligand for E3 Ligase	Others; PROTAC
	(S,R,S)-AHPC TFA (VHL ligand 1 TFA) 是一种 VH032-based VHL ligand，可用于募集 von Hippel-Lindau (VHL)蛋白。它能够利用 linker 与靶蛋白配体连接，形成 PROTAC 分子。
T10706	CCI-006	Mitochondrial Metabolism	Metabolism
	CCI-006 是一种 MLL 重排白血病细胞的选择性抑制剂和化学增敏剂。它能够抑制线粒体呼吸，造成 MLL-r 白血病细胞亚群中无法克服的线粒体去极化和促凋亡未折叠蛋白反应。
T0097L	Pazopanib 帕唑帕尼,GW786034	VEGFR; FGFR; PDGFR; c-Kit; Autophagy	Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
	Pazopanib (GW786034) 是一种小分子抑制剂，可抑制多种具有潜在抗肿瘤活性的蛋白酪氨酸激酶。它抑制VEGFR1、VEGFR2、VEGFR3、PDGFRβ、c-Kit、FGFR1和c-Fms 的IC50分别为10、30、47、84、74、140和146 nM。
T6927	Pamapimod R1503,帕吡莫德,Ro4402257	p38 MAPK; Autophagy	Autophagy; MAPK
	Pamapimod (R1503) 是一种新型的选择性 p38 丝裂原活化蛋白激酶抑制剂，对于p38α和p38β的IC50分别为 14 nM 和 480 nM，Ki 分别为 1.3 nM 和 120 nM，对 p38δ 或 p38γ 亚型没有活性，可研究类风湿关节炎和其他自身免疫性疾病。
T21547	PAF (C16) C16-PAF	ERK; MEK; MAPK; Endogenous Metabolite	MAPK; Metabolism
	PAF (C16) 是有效的 MAPK 和 MEK/ERK 激活剂，可诱导血管通透性增加。PAF (C16) (PAF (C16)) 是血小板活化因子，是一种磷脂衍生介质，也是 PAF G 蛋白偶联受体 (PAFR) 的配体。PAF (C16) 在体外实验中显示出抗凋亡和抗炎活性，通过与其受体（PAF-R）相互作用以执行细胞信号传导来抑制 caspase 依赖性凋亡。
T10373	(R)-Filanesib (R)-ARRY-520	Others	Others
	(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).
T24908	Tyrphostin 47 AG213,AG-213 AG 213	Others	Others
	Tyrphostin 47 inhibits the protein-tyrosine kinase activity of EGF-R.
T26398	7DG 7-DG	Others	Others
	7DG is a selective inhibitor of protein kinase R (PKR).
T35925	(R)-Posenacaftor sodium	Others	Others
	(R)-Posenacaftor ((R)-PTI-801) sodium, the R enantiomer of Posenacaftor, is a cystic fibrosis transmembrane regulator (CFTR) protein modulator. It corrects the folding and trafficking of the CFTR protein, and is utilized in the research of cystic fibrosis (CF)[1].
T16799	RS-246204	Others	Others
	RS-246204 is an R-spondin-1 substitute compound. RS-246204 is able to initiate small intestinal organoids without the use of the R-spondin-1 protein.
T16709	R 59-022 Diacylglycerol kinase inhibitor I,DKGI-I	Others	Others
	R 59-022 is a 5-HTR antagonist and activates protein kinase C (PKC). R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neu
T31864	FPFS-1169 HCl R-(-)-BPAP,FPFS 1169,FPFS-1169 hydrochloride,BPAP-cpd,R-FPFS-1169,FPFS1169	Others	Others
	FPFS-1169 (BPAP-CPD, R-(-)-BPAP, R- FpFS-1169) is a proto-oncogene protein C-Bcl-2 stimulant that is one of the "catecholaminergic and serotonergic enhancers" and may be used for the treatment of Parkinson's disease.
T12616	(R)-CE3F4	Others	Others
	(R)-CE3F4 is a selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1)(IC50 of 4.2 μM),
T38031	(R)-KT109 (R)-KT109	Others	Others
	(R)-KT109 is the (R) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (R)-KT109 is an inhibitor of DAGLβ (IC50 = 0.79 nM) and of DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol . It also inhibits α/β-hydrolase domain-containing protein 6 (ABHD6) with an IC50 value of 2.51 nM. (R)-KT109 is more potent at DAGLβ, DAGLα, and ABHD6 than (S)-KT109 .
T40816	Metalaxyl-M Metalaxyl-M,(R)-Metalaxyl	Others	Others
	Metalaxyl-M ((R)-Metalaxyl), the active (R)-enantiomer of Metalaxyl, is a broad-spectrum fungicide that targets protein and ribosomal RNA synthesis in fungi. It is employed in the research of plant diseases attributed to pathogens from the Oomycota division.
T40078	(R)-Pomalidomide-pyrrolidine	Others	Others
	(R)-Pomalidomide-pyrrolidine, a CRBN ligand, can be conjugated to a protein-targeting ligand via a linker, resulting in the formation of PROTACs.
T12627	(R)-Linezolid (R)-PNU-100766	Others	Others
	(R)-Linezolid is an impurity of Linezolid . Linezolid acts by inhibiting the initiation of bacterial protein synthesis.
T24647	PKR-IN-C51 PKRINC51,PKR IN C51,PKR-inhibitor-C51,PKR inhibitor C51	Others	Others
	PKR-IN-C51 is an inhibitor of protein kinase R. It acts by correcting the aberrant splicing of MBNL1-dependent pre-mRNAs in DM1 cells without affecting the splicing pattern in normal non-DM1 cells.
T69451	R-130823	Others	Others
	R-130823 is a ighly selective inhibition against mitogen-activated protein kinase p38alpha (IC50=22 nM). The release of tumor necrosis factor-alpha, interleukin-1beta, -6 and -8 was inhibited in lipopolysaccharide-stimulated human blood pretreated by R-130823 , with IC50 values of 0.089, 0.066, 0.95 and 0.16 microM, respectively. R-130823 reduced the established hind paw swelling in rat adjuvant-induced arthritis, while methotrexate showed no suppression. In the same model, R-130823 ameliorated ...
T39870	5-HT7R antagonist 1 free base 5-HT7R antagonist 1 free base	Others	Others
	5-HT7R antagonist 1 (free base) is a G protein-biased antagonist for the 5-HT 7 R receptor, with a dissociation constant (K i) of 6.5 nM.
T18648	(R)-TCO-OH	Others	Others
	(R)-TCO-OH is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T77916	(S,R,S)-AHPC-Boc VH032-Boc	Others	Others
	'(S,R,S)-AHPC-Boc (VH032-Boc) 为募集von-Hippel-Lindau (VHL) 蛋白配体的化学化合物，亦应用于PROTAC技术中。'
T18672	(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc VH032-O-Ph-PEG1-NH-Boc	Others	Others
	(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate, specifically designed for targeting the EED protein in PROTAC applications[1].
T71736	AMG-628, (R)-	Others	Others
	AMG-628, (R)- is the R isomer of AMG-628 --- a potent, ATP-competitive inhibitor of Raf kinases. AMG-628 displays selectivity for Raf kinases and inhibits activation of tyrosine protein kinases such as VEGFR2, Lyn, Flt1 and Fms. AMG-628 has shown to inhibit growth, and induces cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation.
T13671L	(S,R,S)-AHPC-Me dihydrochloride VHL ligand 2 dihydrochloride,E3 ligase Ligand 1 dihydrochloride,(S,R,S)-AHPC-Me dihydrochloride (1948273-02-6 free base)	Others	Others
	(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demonstrates potent degradation of BET protein in castration-resistant prostate cancer (CRPC) cells, with a DC50 of less than 1 nM. This compound serves as the VHL ligand, specifically the (S,R,S)-AHPC-based VHL ligand, that facilitates the recruitment of von Hippel-Lindau (VHL) prote...
T18674	(S,R,S)-AHPC-PEG2-acid	Others	Others
	(S,R,S)-AHPC-PEG2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T78660	(S,R)-CFT8634	Epigenetic Reader Domain	Chromatin/Epigenetic
	(S,R)-CFT8634为选择性与口服活性BRD9蛋白降解剂，潜在用途覆盖BRD9介导疾病研究，包含细胞增殖异常等。
T75925	Orexin B, rat, mouse TFA
	Orexin B, rat, mouse (Rat orexin B) TFA，作为一种内源性促进食欲的(Orexin receptor)激动剂，通过结合并激活两个亲密相关的孤儿G蛋白偶联受体OX1-R和OX2-R，促进食物摄入和能量消耗，并在睡眠-觉醒调节中扮演关键角色。
T36282	VH 032 amide-alkylC7-amine VH 032 amide-alkylC7-amine	Others	Others
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T36272	VH032-OH VH 032, phenol	Others	Others
	Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand with terminal hydroxyl ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

化合物

Cat.No: T26019

Synonym: R-59949,R 59949

Target: Others, PKC

Calmidazolium chloride

Cat.No: T10667

Synonym: R 24571,钙调蛋白抑制剂

Target: CaMK, Autophagy

(S,R,S)-AHPC hydrochloride

Cat.No: T4207

Synonym: VHL Ligand 1 hydrochloride,ULM-1,Protein degrader 1 hydrochloride

Target: Others, Ligand for E3 Ligase

Cat.No: T0351

Synonym: Risperidal,R 64 766,利培酮

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, P-gp

Cat.No: T8476

Synonym: RSVA 405

Target: AMPK, STAT, Autophagy

Cat.No: T2614

Target: Apoptosis, PERK, Autophagy

Cat.No: T2654

Target: Apoptosis, PERK, Autophagy

Cat.No: T21976

Target: Prostaglandin Receptor

Cat.No: T22436

Target: VEGFR

ISRIB (trans-isomer)

Cat.No: T6183

Synonym: ISRIB,ISRIB trans-isomer,trans-isomer,trans-ISRIB

Target: Apoptosis, PERK, Autophagy

Y-27632 dihydrochloride

Cat.No: T1725

Synonym: 反式-4-[(R)-1-氨基乙基]-N-(4-吡啶基)环己烷甲酰胺二盐酸盐,Y-27632 2HCl

Target: ROCK, Apoptosis

(S,R,S)-AHPC-Me hydrochloride

Cat.No: T13671

Synonym: VHL ligand 2 hydrochloride,E3 ligase Ligand 1

Target: Others, Ligand for E3 Ligase

Cat.No: T40028

Target: Ligand for E3 Ligase

Cat.No: T60657

Target: TNF, MAPK

(R)-JAK2/STAT3-IN-10a

Cat.No: T72754L

Target: Antiviral

Cat.No: T29061

Synonym: UNC-0006,UNC 0006

Target: cAMP

Cat.No: T8412

Synonym: VH032-NH2,MDK7526,VHL ligand 1

Target: Others, Ligand for E3 Ligase

Cat.No: T8507

Target: Antibacterial

R 59-022 hydrochloride

Cat.No: T72322

Synonym: DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride

Target: 5-HT Receptor, PKC

Cat.No: T19836

Target: DNA/RNA Synthesis, PKA

(S,R,S)-AHPC TFA

Cat.No: T17927

Synonym: VH032-NH2 TFA,VHL ligand 1 TFA

Target: Others, Ligand for E3 Ligase

Cat.No: T10706

Target: Mitochondrial Metabolism

Cat.No: T0097L

Synonym: 帕唑帕尼,GW786034

Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy

Cat.No: T6927

Synonym: R1503,帕吡莫德,Ro4402257

Target: p38 MAPK, Autophagy

Cat.No: T21547

Synonym: C16-PAF

Target: ERK, MEK, MAPK, Endogenous Metabolite

Cat.No: T10373

Synonym: (R)-ARRY-520

Target: Others

Cat.No: T24908

Synonym: AG213,AG-213 AG 213

Target: Others

Cat.No: T26398

Synonym: 7-DG

Target: Others

(R)-Posenacaftor sodium

Cat.No: T35925

Target: Others

Cat.No: T16799

Target: Others

Cat.No: T16709

Synonym: Diacylglycerol kinase inhibitor I,DKGI-I

Target: Others

Cat.No: T31864

Synonym: R-(-)-BPAP,FPFS 1169,FPFS-1169 hydrochloride,BPAP-cpd,R-FPFS-1169,FPFS1169

Target: Others

Cat.No: T12616

Target: Others

Cat.No: T38031

Synonym: (R)-KT109

Target: Others

Cat.No: T40816

Synonym: Metalaxyl-M,(R)-Metalaxyl

Target: Others

(R)-Pomalidomide-pyrrolidine

Cat.No: T40078

Target: Others

Cat.No: T12627

Synonym: (R)-PNU-100766

Target: Others

Cat.No: T24647

Synonym: PKRINC51,PKR IN C51,PKR-inhibitor-C51,PKR inhibitor C51

Target: Others

Cat.No: T69451

Target: Others

5-HT7R antagonist 1 free base

Cat.No: T39870

Synonym: 5-HT7R antagonist 1 free base

Target: Others

Cat.No: T18648

Target: Others

(S,R,S)-AHPC-Boc

Cat.No: T77916

Synonym: VH032-Boc

Target: Others

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc

Cat.No: T18672

Synonym: VH032-O-Ph-PEG1-NH-Boc

Target: Others

Cat.No: T71736

Target: Others

(S,R,S)-AHPC-Me dihydrochloride

Cat.No: T13671L

Synonym: VHL ligand 2 dihydrochloride,E3 ligase Ligand 1 dihydrochloride,(S,R,S)-AHPC-Me dihydrochloride (1948273-02-6 free base)

Target: Others

(S,R,S)-AHPC-PEG2-acid

Cat.No: T18674

Target: Others

Cat.No: T78660

Target: Epigenetic Reader Domain

Orexin B, rat, mouse TFA

Cat.No: T75925

VH 032 amide-alkylC7-amine

Cat.No: T36282

Synonym: VH 032 amide-alkylC7-amine

Target: Others

Cat.No: T36272

Synonym: VH 032, phenol

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5740	25(R,S)-Ruscogenin (25RS)鲁斯可皂苷元,(25RS)-Ruscogenin	Others; HIF	Angiogenesis; Chromatin/Epigenetic; Others
	25(R,S)-Ruscogenin 能够调节 PI3K/Akt/mTOR 信号通路，抑制 MMP-2、MMP-9、uPA、VEGF 和 HIF-1α 的表达，阻碍肝癌转移。它能够抑制 TLR4信号通路，减轻 LPS 诱导的肺内皮细胞凋亡。
T0508	γ-Aminobutyric acid Gamma-aminobutyric acid,4-Aminobutyric acid,4-氨基丁酸,γ-氨基丁酸,GABA,4-Aminobutanoic acid,Piperidic acid	GABA Receptor; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	γ-Aminobutyric acid (4-Aminobutyric acid) 是成年哺乳动物大脑中主要的抑制性神经递质，能够与离子移变 GABA 受体(GABAA) 受体和促代谢受体 (GABAB) 受体结合发挥作用。
TN2173	Salvianolic acid D (R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid,丹酚酸D,丹酚酸 D	Others	Others
	Salvianolic acid D ((R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid) 是一种分离自Salvia miltiorrhiza 中的化合物，有潜在抗血小板作用。
TN1096	Ginsenoside Ra1 人参皂苷 Ra1,人参皂苷Ra1	Others; Tyrosine Kinases	Others; Tyrosine Kinase/Adaptors
	Ginsenoside Ra1 是来自人参的成分。 Ginsenoside Ra1 对缺氧/复氧诱导的蛋白酪氨酸激酶 (PTK) 活化具有显着抑制作用。
T6841	Fumagillin NSC9168,烟曲霉素,Amebacilin	Others; HIV Protease; Antibiotic; Parasite	Microbiology/Virology; Others; Proteases/Proteasome
	Fumagillin (Amebacilin) 由烟曲霉菌中提取的一种抗菌药，有抗阿米巴活性。它通过抑制 HIV-1 viral protein R 活性来抑制 HIV‐1感染。
T6S1369	Vitexin 牡荆素,Apigenin-8-C-glucoside	Antioxidant	oxidation-reduction
	Vitexin 是一种存在于多种药用植物（如榕树、螺旋藻）中的 c-糖基化的黄酮。它具有广泛的药理作用，包括抗氧化，抗癌，抗炎，抗痛觉过敏和神经保护作用。
T35741	Gliovirin	Others	Others
	Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the parasiteT. brucei brucei(IC50= 90 ng/ml), but has no effect on the plant pathogenic fungiR. solani,P. omnivorum,T. basicola,R. arrhizus, andV. dahliaeor the bacteriaB. thuringiensis,P. fluorescens, andX. malvacearumwhen used at concentrations up to 1,000 ng/ml.2,3Gliovirin decrease...
T35624	Ajoene	Others	Others
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 &#181g/ml) and Gram-negative bacteria (MICs = 136-200 &#181g/ml), as well as yeasts (MICs = 10-20 &#181g/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 &#181M), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 &#181M).2It reduces...
T38330	Collinin	Others	Others
	Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a...

天然产物

25(R,S)-Ruscogenin

Cat.No: T5740

Synonym: (25RS)鲁斯可皂苷元,(25RS)-Ruscogenin

Target: Others, HIF

γ-Aminobutyric acid

Cat.No: T0508

Synonym: Gamma-aminobutyric acid,4-Aminobutyric acid,4-氨基丁酸,γ-氨基丁酸,GABA,4-Aminobutanoic acid,Piperidic acid

Target: GABA Receptor, Endogenous Metabolite

Salvianolic acid D

Cat.No: TN2173

Synonym: (R,E)-2-((3-(2-(carboxymethyl)-3,4-dihydroxyphenyl)acryloyl)oxy)-3-(3,4-dihydroxyphenyl)propanoic acid,丹酚酸D,丹酚酸 D

Target: Others

Ginsenoside Ra1

Cat.No: TN1096

Synonym: 人参皂苷 Ra1,人参皂苷Ra1

Target: Others, Tyrosine Kinases

Cat.No: T6841

Synonym: NSC9168,烟曲霉素,Amebacilin

Target: Others, HIV Protease, Antibiotic, Parasite

Cat.No: T6S1369

Synonym: 牡荆素,Apigenin-8-C-glucoside

Target: Antioxidant

Cat.No: T35741

Target: Others

Cat.No: T35624

Target: Others

Cat.No: T38330

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01520	HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) vpr,R ORF protein	HIV-1	E. coli
	HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.8 kDa and the accession number is P0C1P2.
TMPH-01519	HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc) Viral protein R,vpr<...	HIV-1	E. coli
	HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.9 kDa and the accession number is O12160.
TMPJ-00163	R-Spondin 3/RSPO3 Protein, Human, Recombinant (hFc & His) Protein with TSP type-1 repeat,	Human	HEK293 Cells
	R-spondin-3 (RSPO3), also known as Protein with TSP type-1 repeat, Roof plate-specific spondin-3, Thrombospondin type-1 domain-containing protein 2, PWTSR, THSD2 and CRISTIN1, is a member of the thrombospondin type 1 repeat supergene family. RSPO3 is a secreted protein and widely expressed in many tissues. RSPO3 contains two Furin-like repeats which have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases, and one TSP type-...
TMPY-03626	R-Spondin 1/RSPO1 Protein, Human, Recombinant RSPO,R-spondin 1,CRISTIN3	Human	CHO Cells
	R-Spondin 1/RSPO1 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q2MKA7-1.
TMPY-01065	GM-CSFR alpha Protein, Human, Recombinant (His) GM-CSF-R-α,colony stimulating factor 2	Human	HEK293 Cells
	GM-CSFR alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36 kDa and the accession number is P15509-1.
TMPK-00943	PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) PDGF R α/PDGFRA Protein,...	Cynomolgus	HEK293 Cells
	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predic...
TMPY-03197	R-Spondin 1/RSPO1 Protein, Mouse, Recombinant (His) R-spondin,R-spondin 1,Rspondin	Mouse	CHO Cells
	R-Spondin 1/RSPO1 Protein, Mouse, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is B1ASC1.
TMPH-00545	Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc) Immediate-early protein R	EBV	E. coli
	Immediate-early transcription factor that controls the initiation of viral lytic gene expression and lytic reactivation from latency. Triggers lytic replication, and initiates a cellular senescence program in epithelial cells. Upregulates human DCR3/TNFRSF6B by directly binding to its receptor. Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is Q3KS...
TMPY-01147	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) RSPO,CRISTIN3,R-spondin 1	Human	HEK293 Cells
	R-Spondin 1/RSPO1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q2MKA7-1.
TMPY-06418	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) R-spondin 2,CRISTIN2	Human	HEK293 Cells
	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPH-02005	RRAS2 Protein, Human, Recombinant (GST) RRAS2,Ras-related p<...	Human	E. coli
	RRAS2 Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPK-00419	PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi) RHEPDGFRA,PDGFR-2,CD140A,PDGF...	Human	HEK293 Cells
	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The p...
TMPH-02215	TCN1 Protein, Human, Recombinant (His) TCN1,Haptocorrin,Transcobalamin-1...	Human	P. pastoris (Yeast)
	Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
TMPH-02216	TCN1 Protein, Human, Recombinant (His & SUMO) Transcobalamin-1,Haptocorrin,...	Human	E. coli
	Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
TMPK-00420	PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated RHEPDGFRA,PDGFRA,PDGF R ...	Human	HEK293 Cells
	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-...
TMPH-00535	Epstein-Barr virus (strain B95-8) BHRF1 Protein (His) Nuclear antigen,Apoptosis regulator	EBV	E. coli
	Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell.
TMPH-01018	BMP-6 Protein, Human, Recombinant (His) BMP-6,BMP6,VG-1-R,VGR,VG-1-relate...	Human	E. coli
	BMP-6 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.9 kDa and the accession number is P22004.
TMPY-01863	C1QBP Protein, Human, Recombinant (His) SF2p32,p32,GC1QBP,HABP1,gC1qR,gC1Q-R,compl...	Human	E. coli
	C1QBP Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.8 kDa and the accession number is Q07021.
TMPY-02717	GPR37 Protein, Human, Recombinant (His) hET(B)R-LP,PAELR,G protein	Human	HEK293 Cells
	GPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family comprised of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. They only exist in eukaryotes, including yeast, choanoflagellates, and animals. These receptors are bonded and activated by light-sensitive compounds, odors, pheromones, hormones, and n...
TMPY-02511	PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST) LRP,PTP α/PTPRA Protein,...	Human	Baculovirus Insect Cells
	PTPRA is reported to be involved in cancer development and progression through activating the Src family kinase (SFK) signaling pathways. The higher PTPRA level was associated with worse prognosis of SCC patients and PTPRA could promote the cell cycle progression through stimulating the c-Src signaling pathways. The PTPRA gene, which encodes the protein RPTP-alpha, is critical to neurodevelopment. Previous linkage studies, genome-wide association studies, controlled expression analyses and anima...
TMPY-02763	DEP-1 Protein, Human, Recombinant (aa 997-1337, His) HPTPeta,SCC1,protein tyrosine pho...	Human	E. coli
	DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. DEP1 / PTPRJ possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-...
TMPY-02115	R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His) CRISTIN1,THSD2,R-spondin 3,PWTSR	Human	HEK293 Cells
	R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s...
TMPH-02013	PTPRZ1 Protein, Human, Recombinant (His) Protein-tyrosine phosphatase ...	Human	P. pastoris (Yeast)
	Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades. PTPRZ1 Protein, Human, Recombinant (His) is exp...
TMPH-02012	PTPRZ1 Protein, Human, Recombinant (E. coli, His) Protein-tyrosine phosphatase ...	Human	E. coli
	PTPRZ1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-00555	LpxC Protein, E. coli, Recombinant (His) lpxC,UDP-3-O-acyl-N-acetylglucosamine deacetylase,UDP-3-O-[<...	E. coli	E. coli
	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
TMPH-01102	Claudin-3 Protein, Human, Recombinant (B2M & His) Rat ventral prostate.1 pr...	Human	E. coli
	Claudin-3 Protein, Human, Recombinant (B2M & His) is expressed in E. coli.
TMPH-01101	Claudin-3 Protein, Human, Recombinant (Cell-Free, His) Clostridium perfringens enter...	Human	E. coli
	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.1 kDa and the accession number is O15551.
TMPK-00490	GM-CSFR alpha Protein, Cynomolgus, Recombinant (His) CSF2RY,SMDP4,GMCSFR-α,GMR-alpha,C...	Cynomolgus	HEK293 Cells
	In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mamm...
TMPK-00930	GM-CSFR alpha Protein, Mouse, Recombinant (His) CSF2RAX,CSF2RX,CD116,CSF2RAY,GM-C...	Mouse	HEK293 Cells
	In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian...
TMPH-01103	Claudin-3 Protein-VLP, Human, Recombinant (His) Clostridium perfringens enter...	Human	HEK293 Cells
	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 24.7 kDa and the accession number is O15551.
TMPJ-01141	IA2 Protein, Human, Recombinant (aa 687-979, His) PTP IA-2,PTPRN,ICA3,R-PTP-N,ICA 512,Islet ...	Human	E. coli
	IA2 Protein, Human, Recombinant (aa 687-979, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33 KDa and the accession number is Q16849.
TMPJ-01139	IA2 Protein, Human, Recombinant (aa 576-950, His) Islet cell antigen 512,Islet cell autoantigen 3,ICA3,R	Human	E. coli
	IA2 Protein, Human, Recombinant (aa 576-950, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 50 KDa and the accession number is Q16849.
TMPJ-01140	IA2 Protein, Human, Recombinant (aa 607-686 & aa 795-888 , His) Islet cell autoantigen 3,PTPRN,Islet cell antigen 5...	Human	E. coli
	IA2 Protein, Human, Recombinant (aa 607-686 & aa 795-888 , His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26-30 KDa and the accession number is Q16849.
TMPK-00254	GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated GM-CSF-R-α,GMR-α,GMR-alpha,GM-CSF...	Human	HEK293 Cells
	In the first trimester, the GM-CSF-R was found to be present on villous cytotrophoblast and all populations of extravillous trophoblast. Expression by villous syncytiotrophoblast was weak or absent, but this increased markedly by term. GM-CSF-R were also expressed by fetal Hofbauer cells within the mesenchyme of the chorionic villi and by uterine glandular epithelium and decidual macrophages within maternal decidua. GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed...
TMPY-01052	R-Cadherin/CDH4 Protein, Human, Recombinant (His) R-CAD,cadherin 4, type 1, R-cadhe...	Human	HEK293 Cells
	The cadherin superfamily is a large family that engage in both homo- and heterotypic, calcium-dependent, cell-cell adhesion events, and can be divided into at least four subfamilies based on the extracellular (EC) regions and cytoplasmic domains, that is: classical cadherins, desmosomal cadherins, protocadherins, and cadherin-like molecules. Human cadherin 4, type 1, R-cadherin (retinal), also known as CDH4, CAD4 and RCAD, is a classical cadherin from the cadherin superfamily. It is a calcium-de...
TMPY-06725	Jug r 1 Protein, English walnut, Recombinant	English walnut	E. coli
	Jug r 1 Protein, English walnut, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa.
TMPY-03286	hnRNP-R Protein, Human, Recombinant (His & GST) hnRNP-R,HNRPR,heter<...	Human	Baculovirus Insect Cells
	HNRNP R, also known as HNRNPR, is an RNA binding protein. HNRNP R gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). HnRNPs complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The ...
TMPY-00816	GM-CSFR alpha Protein, Human, Recombinant (hFc) CSF2RAX,CSF2R,CD116,CSF2RY,GM-CSF...	Human	HEK293 Cells
	GM-CSFR alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.2 kDa and the accession number is P15509-1.
TMPJ-00356	GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc) GHBP,GHR,Somatotropin recepto...	Mouse	HEK293 Cells
	Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway lead...
TMPY-01448	GHR/Growth Hormone R Protein, Mouse, Recombinant (His) GHR/BP,growth hormone re...	Mouse	HEK293 Cells
	GHR/Growth Hormone R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.3 kDa and the accession number is Q3UP14.
TMPY-04281	GHR/Growth Hormone R Protein, Rat, Recombinant (hFc) growth hormone receptor	Rat	HEK293 Cells
	GHR/Growth Hormone R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55.4 kDa and the accession number is P16310-1.
TMPY-00223	R-Spondin 2/RSPO2 Protein, Mouse, Recombinant (mFc) D430027K22,ftls,AA673245,2610028F08Rik,R-s...	Mouse	HEK293 Cells
	R-Spondin 2/RSPO2 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 47.4 kDa and the accession number is Q8BFU0.
TMPY-02007	GHR/Growth Hormone R Protein, Rat, Recombinant (His) growth hormone receptor	Rat	HEK293 Cells
	GHR/Growth Hormone R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.6 kDa and the accession number is P16310-1.
TMPK-01050	PDGF R beta/CD140b Protein, Canine, Recombinant (His) JTK12,PDGF R β,PDGFR-β,PDGFR,PDGF...	Canine	HEK293 Cells
	PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3.
TMPK-00481	PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His) PDGF R beta,PDGFRB,PDGFR-2,PDGF-<...	Cynomolgus	HEK293 Cells
	Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target.
TMPK-00806	GHR/Growth Hormone R Protein, Human, Recombinant (His) GHR/BP,GH receptor,GHBP,GHR	Human	HEK293 Cells
	Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.
TMPY-00977	GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc) growth hormone receptor,...	Mouse	HEK293 Cells
	GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is Q3UP14.
TMPK-00986	IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His) SCIDX1,IL2RG,gammaC,γC,CIDX,IL-2 R γ/CD132...	Cynomolgus	HEK293 Cells
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant...
TMPK-00421	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) PDGFR1,CD140B,PDGFR-2,PDGF R β/CD...	Human	HEK293 Cells
	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
TMPK-00422	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated PDGFR-2,PDGF R β/CD140b,PDGFR1,CD...	Human	HEK293 Cells
	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
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重组蛋白

HIV-1 (group M, subtype K, isolate 96CM-MP535) Protein Vpr (His & Myc)

Cat.No: TMPH-01520

Species: HIV-1

Expression System: E. coli

HIV-1 (group M, subtype C, isolate 92BR025) Protein Vpr (His & Myc)

Cat.No: TMPH-01519

Species: HIV-1

Expression System: E. coli

R-Spondin 3/RSPO3 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00163

Species: Human

Expression System: HEK293 Cells

R-Spondin 1/RSPO1 Protein, Human, Recombinant

Cat.No: TMPY-03626

Species: Human

Expression System: CHO Cells

GM-CSFR alpha Protein, Human, Recombinant (His)

Cat.No: TMPY-01065

Species: Human

Expression System: HEK293 Cells

PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00943

Species: Cynomolgus

Expression System: HEK293 Cells

R-Spondin 1/RSPO1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03197

Species: Mouse

Expression System: CHO Cells

Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc)

Cat.No: TMPH-00545

Species: EBV

Expression System: E. coli

R-Spondin 1/RSPO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01147

Species: Human

Expression System: HEK293 Cells

R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06418

Species: Human

Expression System: HEK293 Cells

RRAS2 Protein, Human, Recombinant (GST)

Cat.No: TMPH-02005

Species: Human

Expression System: E. coli

PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00419

Species: Human

Expression System: HEK293 Cells

TCN1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02215

Species: Human

Expression System: P. pastoris (Yeast)

TCN1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02216

Species: Human

Expression System: E. coli

PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00420

Species: Human

Expression System: HEK293 Cells

Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)

Cat.No: TMPH-00535

Species: EBV

Expression System: E. coli

BMP-6 Protein, Human, Recombinant (His)

Cat.No: TMPH-01018

Species: Human

Expression System: E. coli

C1QBP Protein, Human, Recombinant (His)

Cat.No: TMPY-01863

Species: Human

Expression System: E. coli

GPR37 Protein, Human, Recombinant (His)

Cat.No: TMPY-02717

Species: Human

Expression System: HEK293 Cells

PTP alpha/PTPRA Protein, Human, Recombinant (aa 174-793, His & GST)

Cat.No: TMPY-02511

Species: Human

Expression System: Baculovirus Insect Cells

DEP-1 Protein, Human, Recombinant (aa 997-1337, His)

Cat.No: TMPY-02763

Species: Human

Expression System: E. coli

R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)

Cat.No: TMPY-02115

Species: Human

Expression System: HEK293 Cells

PTPRZ1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02013

Species: Human

Expression System: P. pastoris (Yeast)

PTPRZ1 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02012

Species: Human

Expression System: E. coli

LpxC Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00555

Species: E. coli

Expression System: E. coli

Claudin-3 Protein, Human, Recombinant (B2M & His)

Cat.No: TMPH-01102

Species: Human

Expression System: E. coli

Claudin-3 Protein, Human, Recombinant (Cell-Free, His)

Cat.No: TMPH-01101

Species: Human

Expression System: E. coli

GM-CSFR alpha Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00490

Species: Cynomolgus

Expression System: HEK293 Cells

GM-CSFR alpha Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00930

Species: Mouse

Expression System: HEK293 Cells

Claudin-3 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-01103

Species: Human

Expression System: HEK293 Cells

IA2 Protein, Human, Recombinant (aa 687-979, His)

Cat.No: TMPJ-01141

Species: Human

Expression System: E. coli

IA2 Protein, Human, Recombinant (aa 576-950, His)

Cat.No: TMPJ-01139

Species: Human

Expression System: E. coli

IA2 Protein, Human, Recombinant (aa 607-686 & aa 795-888 , His)

Cat.No: TMPJ-01140

Species: Human

Expression System: E. coli

GM-CSFR alpha Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00254

Species: Human

Expression System: HEK293 Cells

R-Cadherin/CDH4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01052

Species: Human

Expression System: HEK293 Cells

Jug r 1 Protein, English walnut, Recombinant

Cat.No: TMPY-06725

Species: English walnut

Expression System: E. coli

hnRNP-R Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03286

Species: Human

Expression System: Baculovirus Insect Cells

GM-CSFR alpha Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00816

Species: Human

Expression System: HEK293 Cells

GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00356

Species: Mouse

Expression System: HEK293 Cells

GHR/Growth Hormone R Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01448

Species: Mouse

Expression System: HEK293 Cells

GHR/Growth Hormone R Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04281

Species: Rat

Expression System: HEK293 Cells

R-Spondin 2/RSPO2 Protein, Mouse, Recombinant (mFc)

Cat.No: TMPY-00223

Species: Mouse

Expression System: HEK293 Cells

GHR/Growth Hormone R Protein, Rat, Recombinant (His)

Cat.No: TMPY-02007

Species: Rat

Expression System: HEK293 Cells

PDGF R beta/CD140b Protein, Canine, Recombinant (His)

Cat.No: TMPK-01050

Species: Canine

Expression System: HEK293 Cells

PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00481

Species: Cynomolgus

Expression System: HEK293 Cells

GHR/Growth Hormone R Protein, Human, Recombinant (His)

Cat.No: TMPK-00806

Species: Human

Expression System: HEK293 Cells

GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-00977

Species: Mouse

Expression System: HEK293 Cells

IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00986

Species: Cynomolgus

Expression System: HEK293 Cells

PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00421

Species: Human

Expression System: HEK293 Cells

PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00422

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T35790	Palmitic acid-1,2,3,4-13C4 Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
	Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...

同位素标记化合物

Palmitic acid-1,2,3,4-13C4

Cat.No: T35790

Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

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