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Search Results for " protein k2 "
Targets Recommended: MAPK

2

抑制剂 & 化合物

3

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Cat. No. Product Name Target Signaling Pathways
T9034 MK2-IN-3

MK2 Inhibitor III

MAPK MAPK
MK2-IN-3 (MK2 Inhibitor III) 是选择性的 MAPKAP-K2 (MK-2)抑制剂(IC50:8.5 nM),能够抑制 U937 细胞及体内 TNFα 的生成。
T12058 MK2-IN-3 hydrate

MK-2 Inhibitor III

ERK; MAPK; MNK MAPK
MK2-IN-3 hydrate (MK-2 Inhibitor III) 是一种口服有活性的、ATP 竞争性的MAPKAP-K2 (MK-2)选择性抑制剂(IC50:0.85 nM)。

化合物

MK2-IN-3
Cat.No: T9034
Synonym: MK2 Inhibitor III
Target: MAPK
MK2-IN-3 hydrate
Cat.No: T12058
Synonym: MK-2 Inhibitor III
Target: ERK, MAPK, MNK
Cat. No. Product Name Species Expression System
TMPH-03672 Vaccinia virus (strain Western Reserve) K3 Protein (His & SUMO)

Protein K2,Protein K3

VACV E. coli
Viral mimic of eIF-2-alpha that acts as a pseudosubstrate for EIF2AK2/PKR kinase. Inhibits therefore eIF-2-alpha phosphorylation by host EIF2AK2/PKR kinase and prevents protein synthesis shutoff. Vaccinia virus (strain Western Reserve) K3 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 26.6 kDa and the accession number is P18378.
TMPH-03671 Vaccinia virus (strain Western Reserve) K3 Protein (His)

Protein K2,Protein K3

VACV P. pastoris (Yeast)
Viral mimic of eIF-2-alpha that acts as a pseudosubstrate for EIF2AK2/PKR kinase. Inhibits therefore eIF-2-alpha phosphorylation by host EIF2AK2/PKR kinase and prevents protein synthesis shutoff. Vaccinia virus (strain Western Reserve) K3 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 12.6 kDa and the accession number is P18378.
TMPH-03665 Vaccinia virus (strain Copenhagen) OPG185 Protein (His)

Hemagglutinin,Protein OPG185,OPG185

VACV E. coli
Prevents cell to cell fusion by interacting with and directing the viral K2 protein on the host plasma membrane. The A56-K2 complex associates with components of the entry fusion complex (EFC) presumably to avoid superinfection and syncytium formation. Via its interaction with C3/VCP protein, protects the infected cell and probably also the extracellular enveloped virus from complement attack. Vaccinia virus (strain Copenhagen) OPG185 Protein (His) is expressed in E. coli expression system with ...

重组蛋白

Vaccinia virus (strain Western Reserve) K3 Protein (His & SUMO)
Cat.No: TMPH-03672
Species: VACV
Expression System: E. coli
Vaccinia virus (strain Western Reserve) K3 Protein (His)
Cat.No: TMPH-03671
Species: VACV
Expression System: P. pastoris (Yeast)
Vaccinia virus (strain Copenhagen) OPG185 Protein (His)
Cat.No: TMPH-03665
Species: VACV
Expression System: E. coli
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