Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38196 |
Prostaglandin F2α isopropyl ester
Prostaglandin F2α isopropyl ester |
Others | Others |
PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application in studies on intraocular pressure. The ester functionality is readily hydrolyzed in vivo to release the active compound PGF2α. When administered topically to the eyes of cynomolgus monkeys, a 5 μg dose reduces intraocular pressure by 68% after the fourth day of treatment. | |||
T36155 |
15(S)-15-methyl Prostaglandin F2α isopropyl ester
15(S)-15-methyl Prostaglandin F2α isopropyl ester |
Others | Others |
15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor. 15(S)-15-methyl PGF2α isopropyl ester is a lipophilic analog of 15(S)-15-methyl PGF2α methyl ester, which may be hydrolyzed in vivo to the fully active free acid. |