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1

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T81389 Properdistatin

Properdistatin是一种衍生自thrombospondin-1 (TSP-1)结构域的小分子肽,其作用机制主要在于抑制血管生成并促进血管功能的改善,因此在黑色素瘤的研究中显示出应用潜力。

化合物

Properdistatin
Cat.No: T81389
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-02844 Properdin Protein, Mouse, Recombinant (His)

Cfp,Properdin,Complement factor P

Mouse E. coli
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b).
TMPH-02845 Properdin Protein, Mouse, Recombinant (His & Myc)

Properdin,Complement factor P,Cfp

Mouse HEK293 Cells
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b).
TMPJ-00149 Complement Factor D/CFD Protein, Mouse, Recombinant (His)

C3 convertase activator,28 kDa adipocyte protein,Cfd,Adipsin...

Mouse HEK293 Cells
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the...
TMPH-03271 Complement factor D Protein, Rat, Recombinant (His & Myc)

Adn,C3 convertase activator,Properdin factor D,Comp...

Rat HEK293 Cells
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 29.8 kDa and the accession number is P32038.
TMPH-03272 Complement factor D Protein, Rat, Recombinant (His)

Adipsin,Df,Adn,C3 convertase activator,Complement factor D,E...

Rat P. pastoris (Yeast)
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

重组蛋白

Properdin Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02844
Species: Mouse
Expression System: E. coli
Properdin Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02845
Species: Mouse
Expression System: HEK293 Cells
Complement Factor D/CFD Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00149
Species: Mouse
Expression System: HEK293 Cells
Complement factor D Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03271
Species: Rat
Expression System: HEK293 Cells
Complement factor D Protein, Rat, Recombinant (His)
Cat.No: TMPH-03272
Species: Rat
Expression System: P. pastoris (Yeast)
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