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Cat. No. | Product Name | ||
---|---|---|---|
L4600 | 植物来源化合物库 | 3048 compounds | |
3048 个植物来源天然产物的独特集合,来自277类植物的精心之选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T23508 |
VU 0255035
|
AChR | Neuroscience |
VU 0255035 是高度选择性、竞争性和血脑屏障通透性的毒蕈碱 M1 受体拮抗剂,IC50为 130 nM,可减少毛果芸香碱诱导的小鼠癫痫发作。 | |||
T13615 |
Cinperene
桂哌林,R5046 |
Others | Others |
Cinperene is an atropine-like compound that can block pilocarpine-induced salivation and lacrimation. | |||
T70292 |
DDPM-2571 HCl
|
Others | Others |
DDPM-2571 is a highly potent and in vivo active inhibitor of GABA transporter subtype 1 with anticonvulsant, anxiolytic, antidepressant and antinociceptive properties. DDPM-2571 was quickly distributed into the brain and was highly effective in the prevention of chemically-induced seizures (pentylenetetrazole and pilocarpine models) and 6-Hz convulsions. It demonstrated significant anxiolytic-like and antidepressant-like properties. DDPM-2571 had antinociceptive properties, both in the hot plate... | |||
T81674 |
NIR-FP
|
||
NIR-FP是一款用于超氧阴离子(O2-)检测的近红外荧光探针,具备高灵敏度和高选择性。由于O2-是活性氧种(ROS)的关键前体,此探针能有效动态监测由超氧阴离子引发的铁死亡介导的癫痫模型。这些模型包括红藻氨酸诱导的慢性癫痫模型、Pentylenetetrazole诱导的急性癫痫模型以及毛果芸香碱诱导的癫痫模型。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0804 |
Pilocarpine Hydrochloride
NSC 5746 HCl,盐酸毛果芸香碱,Pilocarpine HCl,(+)-Pilocarpine hydrochloride |
AChR | Neuroscience |
Pilocarpine Hydrochloride (NSC 5746 HCl) 是一种 M3 型毒蕈碱乙酰胆碱受体激动剂,用于制作癫痫实验模型 | |||
T1231 |
Pilocarpine nitrate
匹鲁卡品硝酸盐,Pilagan,硝酸毛果芸香碱,Pilofrin |
AChR | Neuroscience |
Pilocarpine nitrate (Pilagan) 是 M3 型毒蕈碱乙酰胆碱受体激动剂,可用于治疗青光眼。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02964 |
Calcineurin B/PPP3R1 Protein, Human, Recombinant (His)
protein phosphatase 3, regulatory subunit B, alpha,CNB1,CALN... |
Human | Baculovirus Insect Cells |
PPP3R1 belongs to the calcineurin regulatory subunit family. It is a regulatory subunit of calcineurin. Calcineurin is composed of two subunits: calcineurin A (CnA) and calcineurin B (CnB). Dephosphorylation of the nuclear factor of activated T-cells (NF-AT) by Calcineurin is essential for NF-AT activation, nuclear translocation, and early gene expression in T-cells. PPP3R1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase which takes a vital part in the T cell activatio... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIJ-0266 |
Pilocarpine-d3 HCl
|
||
Pilocarpine-d3 HCl 是 Pilocarpine HCl 的氘代化合物。Pilocarpine HCl 的 CAS 号为 54-71-7。Pilocarpine Hydrochloride 是一种 M3 型毒蕈碱乙酰胆碱受体激动剂,用于制作癫痫实验模型 |