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Search Results for " pp1 "
Targets Recommended: Apoptosis EGFR Bcr-Abl Src c-Kit

38

抑制剂 & 化合物

3

天然产物

1

TargetMol 试剂盒

18

重组蛋白

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Cat. No. Product Name Form Specificity Of Inhibition
C0003 Phosphatase Inhibitor Cocktail II (100× DMSO)

磷酸酶抑制剂 Cocktail II (100× DMSO)

Solution (<em>1</em>00× in DMSO) Alkaline phosphatases, Ser/Thr phosphatases, Acid and <em>PP</em><em>1</em> and <em>PP</em>2A

TargetMol 试剂盒

磷酸酶抑制剂 Cocktail II (100× DMSO)
Cat.No: C0003
Cat. No. Product Name Target Signaling Pathways
T6196 PP1

EI 275,AGL 1872

Apoptosis; EGFR; Bcr-Abl; Src; c-Kit Angiogenesis; Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; Tyrosine Kinase/Adaptors
PP1 (AGL 1872) 是一种选择性有效 Src 家族抑制剂,抑制 Lck 和Fyn,IC50分别为 5 和 6 nM。
T2153 1-NM-PP1

PP1 Analog II,1 nM-PP1

Serine/threonin kinase; CDK; Src Angiogenesis; Cell Cycle/Checkpoint; Metabolism; Tyrosine Kinase/Adaptors
1-NM-PP1 (PP1 Analog II) 是一种有效的Src 家族激酶抑制剂,是一种细胞渗透性 PP1 类似物,对 v-Src-as1 与 c-Fyn-as1 的IC50值分别为 4.3 nM、3.2 nM。
T3935 1-Naphthyl PP1

4 -氨基- 1 -叔丁基- 3 -(1' -萘基)吡唑并[3,4 - D]嘧啶,1-NA-PP 1

Src Angiogenesis; Tyrosine Kinase/Adaptors
1-Naphthyl PP1 (1-NA-PP 1) 是选择性的src 家族激酶抑制剂,能够抑制 v-Src (IC50:1.0 μM)、c-Fyn (IC50:0.6 μM)、c-Abl (IC50:0.6 μM)、CDK2 (IC50:18 μM) 和 CAMK II (IC50:22 μM)。
T7371 1-Naphthyl PP1 hydrochloride

1-叔丁基-3-(1-萘基)-1H-吡唑并[3,4-D]嘧啶-4-胺盐酸盐,1-NA-PP 1 hydrochloride

Src Angiogenesis; Tyrosine Kinase/Adaptors
1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) 是选择性的 src 家族激酶抑制剂,能够抑制 v-Src (IC50:1.0 μM)、c-Fyn (IC50:0.6 μM)、c-Abl (IC50:0.6 μM)、CDK2 (IC50:18 μM)、CAMK II (IC50:22 μM)。
T21678 3MB-PP1

PLK Cell Cycle/Checkpoint
3MB-PP1是嘌呤类似物,是一种 Polo 样激酶 1 (Plk1) 抑制剂。在表达类似物敏感的 Plk1 等位基因的细胞中,3MB-PP1 通过靶向 Plk1 阻断有丝分裂进程和细胞分裂。3MB-PP1 特异性抑制类似物敏感的 Ssn3 (Cdk8)。3MB-PP1 抑制 Leu93 突变 Zipper-interacting protein kinase(Leu93-ZIPK),IC50为2 μM。3MB-PP1 可用于细胞分裂和白色念珠菌 (Candida albicans) 菌丝形成的研究。
T41113 3BrB-PP1

3BrB-PP1

Others Others
3BrB-PP1 is an ATP-competitive analog that exhibits specific inhibitory activity towards protein kinase. It is effective in inhibiting protein kinase with mutations in the ATP-binding pocket, specifically the mutation of Thr97 within Sty1's ATP-binding pocket.
T60718 3-IN-PP1

Others Others
3-IN-PP1是一种针对蛋白激酶D(PKD)家族成员PKD1、PKD2和PKD3具有高效抑制作用的抑制剂,IC50值分别为108、94和108 nM。此外,3-IN-PP1作为一种广谱抗癌剂,能抑制多种肿瘤细胞的生长,适用于癌症研究领域。
T14022 2OH-BNPP1

Others Others
2OH-BNPP1 是BUB1 kinase 抑制剂,可用于研究癌症。
T28818 SMAPP1

Others Others
SMAPP1 is an activator of protein phosphatase 1 (PP1). SMAPP1 induces PP1 activity in vitro and activates latent HIV-1 provirus in cultured and primary T cells.
TMAZ-0259P Anti-TPP1 Monoclonal Antibody-PE

Anti-TPP1 Monoclonal Antibody-PE is a biotin-conjugated humanized rabbit antibody targeting TPP1. Anti-TPP1 Monoclonal Antibody-PE can be used ELISA, FACS.
TP1963 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide

cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide

Potent, selective peptide agonist for the neuropeptide Y Y5 receptor (IC50 values for inhibition of NPY binding to human Y5, Y1, Y2 and Y4 receptors are 0.24, 530, > 500, and 51 nM respectively, Ki at Y5 = 0.1 - 0.15 nM). Stimulates food intake in vivo.
T61782 NPP1-IN-1

Others Others
NPP1-IN-1 is a highly potent inhibitor of NPP enzymes, effectively inhibiting NPP1 with an IC 50 value of 0.15 μM and NPP3 with an IC 50 value of 40 μM [1].
TMAZ-0259B Anti-TPP1 Monoclonal Antibody-Biotin

Anti-TPP1 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting TPP1. Anti-TPP1 Monoclonal Antibody-Biotin can be used ELISA, FACS.
TMAZ-0259A5 Anti-TPP1 Monoclonal Antibody-AF555

Anti-TPP1 Monoclonal Antibody-AF555 is a biotin-conjugated humanized rabbit antibody targeting TPP1. Anti-TPP1 Monoclonal Antibody-AF555 can be used ELISA, FACS.
T80291 PP113

PP113是一种具有广谱抗菌性的抗菌肽,能有效作用于多种革兰氏阴性及革兰氏阳性细菌。对E.coli (MIC: 73.3 uM)、B. subtilis (MIC: 23.3 uM)、S. aureus (MIC: 13 uM)、S. lutea (MIC: 16.7 uM)及B. pumilus (MIC: 23.3 uM)表现出不同程度的最小抑菌浓度(MIC)。
T37431 ENPP1 Inhibitor C

ENPP1 Inhibitor C

Others Others
ENPP1 inhibitor C is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50 = 0.26 μM in a cell-free assay).1 It is selective for ENPP1 over ENPP2-7 at 10 μM. ENPP1 inhibitor C decreases ENPP1 activity in MDA-MB-231 human breast and C6 rat glioma cancer cells when used at a concentration of 10 μM. |1. Kawaguchi, M., Han, X., Hisada, T., et al. Development of an ENPP1 fluorescence probe for inhibitor screening, cellular imaging, and prognostic assessment of malignant brea...
T69560 ENPP1 inhibitor 43

Others Others
ENPP1 inhibitor 43 is a novel small molecule for cancer immunotherapy.
TMAZ-0259A Anti-TPP1 Monoclonal Antibody-APC

Anti-TPP1 Monoclonal Antibody-APC is a biotin-conjugated humanized rabbit antibody targeting TPP1. Anti-TPP1 Monoclonal Antibody-APC can be used ELISA, FACS.
TMAZ-0259A4 Anti-TPP1 Monoclonal Antibody-AF488

Anti-TPP1 Monoclonal Antibody-AF488 is a biotin-conjugated humanized rabbit antibody targeting TPP1. Anti-TPP1 Monoclonal Antibody-AF488 can be used ELISA, FACS.
T80288 PP13

PP13是一种具有广谱抗菌活性的抗菌肽,有效针对多种革兰氏阴性及革兰氏阳性细菌,包括E.coli (MIC: 16.7 uM)、B. subtilis (MIC: 13.3 uM)、S. aureus (MIC: 23.3 uM)、S. lutea (MIC: 8.0 uM)以及B. pumilu (MIC: 9.0 uM)。
T75913 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide 为高效且选择性的神经肽 YY5 受体激动剂,其与 hY5 受体的结合 IC50 值为 0.24 nM,已知可促进饮食摄入。
T80290 PP102

PP102为一种抗菌肽,针对革兰氏阴性及革兰氏阳性细菌展现出抗菌效能,具体作用于B. subtilis(MIC: 25 uM)、S. aureus(MIC: 13 uM)、S. lutea(MIC: 63 uM)和B. pumilu(MIC: 23 uM)。
T2415 PP121

Apoptosis; VEGFR; Bcr-Abl; PDGFR; Src; mTOR; Hck Angiogenesis; Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
PP121是一种多靶点激酶抑制剂,抑制 PDGFR、Hck、mTOR、VEGFR2、Src、Abl、DNK-PK 的 IC50值分别为2、8、10、12、14、18、60 nM。
TMAZ-0259A6 Anti-TPP1 Monoclonal Antibody-AF647

Anti-TPP1 Monoclonal Antibody-AF647 is a biotin-conjugated humanized rabbit antibody targeting TPP1. Anti-TPP1 Monoclonal Antibody-AF647 can be used ELISA, FACS.
T3045 Salubrinal

Apoptosis; Phosphatase; PERK; Autophagy; HSV Apoptosis; Autophagy; Metabolism; Microbiology/Virology
Salubrinal 是一种磷酸酶抑制剂 ,对真核翻译起始因子 2 亚基 (eIF2α) 发挥作用。它作为双特异性磷酸酶 2 抑制剂,抑制抗胶原蛋白抗体诱导的关节炎。它具有抗HSV-1病毒的活性,并抑制由HSV-1蛋白 ICP34.5 介导的eIF2α的去磷酸化。
T32108 HXJ42

HXJ-42,HXJ 42

Others Others
HXJ42 是一种 PP1 类似物,可选择性地有效作用于野生型 ZAP-70 (AS)。
T2747 Endothall

Phosphatase; Others Metabolism; Others
Endothall 是蛋白磷酸酶 2A (PP2A) 抑制剂,能够抑制PP2A (IC50: 90 nM) 和 PP1 (IC50: 5 uM) 。它可作为除草剂,在癌症化疗过程中也能够发挥作用。
T14859 Calyculin A

(-)-Calyculin A

Others Others
Calyculin A is a potent and cell-permeable inhibitor of protein phosphatase 1 (PP1; IC50s: 2 nM). It also is a protein phosphatase 2A (PP2A) inhibitor (IC50s: 0.5-1 nM).
T13095 Tautomycin

Others Others
Tautomycin is a potent and specific protein phosphatases 1 and 2A inhibitor (Kiapp of 0.16 nM and 0.4 nM for PP1 and PP2A, respectively), and is an antifungal antibiotic isolated from the bacterium Streptomyces verticillatus.
T70441 1E7-03

Others Others
1E7-03 is an inhibitor of HIV-1 transcription, by targeting host Protein Phosphatase-1 (PP1).
T68749 EBOV-IN-C31

Others Others
EBOV-IN-C31 is a novel PP1-targeting Ebola Virus (EBOV) inhibitor with improved pharmacological properties.
TP2054 Calcineurin Autoinhibitory Peptide

Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).
TP1698 Microcystin-LA

Microcystin LA, a natural toxin, exerts its cytotoxic exects by inhibiting the serine-threonine protein phosphatases PP1 and PP2A with IC50s of 0.3 and 0.3 nM, respectively.
T39183 Okadaic acid ammonium salt

Others Others
Okadaic acid ammonium salt, a marine toxin, serves as an inhibitor of protein phosphatases (PP), displaying a higher affinity for PP2A (IC 50 =0.1-0.3 nM) alongside inhibitory effects on PP1 (IC 50 =15-50 nM), PP3 (IC 50 =3.7-4 nM), PP4 (IC 50 =0.1 nM), and PP5 (IC 50 =3.5 nM), but does not affect PP2C. By inhibiting PPs, this compound promotes protein phosphorylation and acts as a tumor promoter. Additionally, it is involved in inducing tau phosphorylation.
T68458 Fostriecin (free base)

Others Others
Fostriecin (free base) is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively). It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 μM, respectively) and does not inhibit PP2B. Through its effects on protein phosphatases, fostriecin increases the level of histone H3 phosphorylation and may alter epigenetic regulation of cell proliferation. On a related note, fostriecin was first identified as an antitumor antib...
T68721 Cantharidin imide

Others Others
Cantharidin imide is a PP1/2A inhibitor found in Canarthis vesicatoria. It inhibits proliferation of colorectal cancer cells, increases MCP-1, IL-6, and IL-β levels, and inhibits differentiation and resorptive activity of osteoclasts. This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
T35613 Cytostatin (sodium salt)

Others Others
Cytostatin (sodium salt) is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice. It induces apoptosis of FS3 mouse fibrosarcoma cells (IC50 = 3.1 μg/ml). Cytostatin (sodium salt) potently and selectively inhibits protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), while having no effect agai...
T35777 Nodularin

Others Others
The cyanobacterium Nodularia spumigena often contaminates the drinking water of rural communities in developing countries and accumulates in mussels, flounder, and cod from the northern Baltic Sea. Nodularin is a hepatotoxic monocylic pentapeptide produced by the N. spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC50 values of 1.8 and 0.026 nM, respectively. PP2B is inhibited to a lesser extent with an IC50 of 1.8 μM. No apparent inhibitory eff...

化合物

PP1
Cat.No: T6196
Synonym: EI 275,AGL 1872
Target: Apoptosis, EGFR, Bcr-Abl, Src, c-Kit
1-NM-PP1
Cat.No: T2153
Synonym: PP1 Analog II,1 nM-PP1
Target: Serine/threonin kinase, CDK, Src
1-Naphthyl PP1
Cat.No: T3935
Synonym: 4 -氨基- 1 -叔丁基- 3 -(1' -萘基)吡唑并[3,4 - D]嘧啶,1-NA-PP 1
Target: Src
1-Naphthyl PP1 hydrochloride
Cat.No: T7371
Synonym: 1-叔丁基-3-(1-萘基)-1H-吡唑并[3,4-D]嘧啶-4-胺盐酸盐,1-NA-PP 1 hydrochloride
Target: Src
3MB-PP1
Cat.No: T21678
Synonym:
Target: PLK
3BrB-PP1
Cat.No: T41113
Synonym: 3BrB-PP1
Target: Others
3-IN-PP1
Cat.No: T60718
Synonym:
Target: Others
2OH-BNPP1
Cat.No: T14022
Synonym:
Target: Others
SMAPP1
Cat.No: T28818
Synonym:
Target: Others
Anti-TPP1 Monoclonal Antibody-PE
Cat.No: TMAZ-0259P
Synonym:
Target:
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide
Cat.No: TP1963
Synonym: cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide,[cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide
Target:
NPP1-IN-1
Cat.No: T61782
Synonym:
Target: Others
Anti-TPP1 Monoclonal Antibody-Biotin
Cat.No: TMAZ-0259B
Synonym:
Target:
Anti-TPP1 Monoclonal Antibody-AF555
Cat.No: TMAZ-0259A5
Synonym:
Target:
PP113
Cat.No: T80291
Synonym:
Target:
ENPP1 Inhibitor C
Cat.No: T37431
Synonym: ENPP1 Inhibitor C
Target: Others
ENPP1 inhibitor 43
Cat.No: T69560
Synonym:
Target: Others
Anti-TPP1 Monoclonal Antibody-APC
Cat.No: TMAZ-0259A
Synonym:
Target:
Anti-TPP1 Monoclonal Antibody-AF488
Cat.No: TMAZ-0259A4
Synonym:
Target:
PP13
Cat.No: T80288
Synonym:
Target:
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA
Cat.No: T75913
Synonym:
Target:
PP102
Cat.No: T80290
Synonym:
Target:
PP121
Cat.No: T2415
Synonym:
Target: Apoptosis, VEGFR, Bcr-Abl, PDGFR, Src, mTOR, Hck
Anti-TPP1 Monoclonal Antibody-AF647
Cat.No: TMAZ-0259A6
Synonym:
Target:
Salubrinal
Cat.No: T3045
Synonym:
Target: Apoptosis, Phosphatase, PERK, Autophagy, HSV
HXJ42
Cat.No: T32108
Synonym: HXJ-42,HXJ 42
Target: Others
Endothall
Cat.No: T2747
Synonym:
Target: Phosphatase, Others
Calyculin A
Cat.No: T14859
Synonym: (-)-Calyculin A
Target: Others
Tautomycin
Cat.No: T13095
Synonym:
Target: Others
1E7-03
Cat.No: T70441
Synonym:
Target: Others
EBOV-IN-C31
Cat.No: T68749
Synonym:
Target: Others
Calcineurin Autoinhibitory Peptide
Cat.No: TP2054
Synonym:
Target:
Microcystin-LA
Cat.No: TP1698
Synonym:
Target:
Okadaic acid ammonium salt
Cat.No: T39183
Synonym:
Target: Others
Fostriecin (free base)
Cat.No: T68458
Synonym:
Target: Others
Cantharidin imide
Cat.No: T68721
Synonym:
Target: Others
Cytostatin (sodium salt)
Cat.No: T35613
Synonym:
Target: Others
Nodularin
Cat.No: T35777
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T4839 Ac-Ala-OH

N-Acetylalanine,N-Acetyl-L-alanine,N-乙酰-L-丙氨酸

Others; Endogenous Metabolite Metabolism; Others
Ac-Ala-OH (N-Acetyl-L-alanine) 是鸟嘌呤核苷酸结合蛋白G(I)/G(S)/G(O) γ -2亚基、髓鞘碱性蛋白、GTP-结合核蛋白 Ran、原肌球蛋白 α - 4链、HIV-1 Rev 结合蛋白2、Xaa-Pro 二肽酶、胸腺酶 β -10、肌动蛋白样蛋白3、丙氨酸转氨酶、丝氨酸/苏氨酸蛋白磷酸酶PP1 - β催化亚基、10 kda 热休克蛋白(线粒体)、钙调蛋白和 β -1-syntrophin 的底物。
T16381 Okadaic acid

Others Others
Okadaic acid is a non-comepetitive, selective and reversible serine/threonine-specific protein phosphatases 1 (PP1), PP2A, and PP3 inhibitor (IC50s: 10-15 nM, 0.5 nM, and 4 nM, respectively). Okadaic acid is extracted from black sponges of the genus Halic
T37055 Cytostatin

Others Others
Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice. It induces apoptosis of FS3 mouse fibrosarcoma cells (IC50 = 3.1 μg/ml). Cytostatin potently and selectively inhibits protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), while having no effect against PP1, PP2B, or PP5.

天然产物

Ac-Ala-OH
Cat.No: T4839
Synonym: N-Acetylalanine,N-Acetyl-L-alanine,N-乙酰-L-丙氨酸
Target: Others, Endogenous Metabolite
Okadaic acid
Cat.No: T16381
Synonym:
Target: Others
Cytostatin
Cat.No: T37055
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-00499 PPP1CA Protein, Canine, Recombinant (His & Myc)

PPP1CA,Serine/threonine-protein phosphatas...

Canine E. coli
PPP1CA Protein, Canine, Recombinant (His & Myc) is expressed in E. coli.
TMPH-02098 PPP1CB Protein, Human, Recombinant (His)

PPP1CB,Serine/threonine-protein phosphatas...

Human E. coli
PPP1CB Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00944 PPP1CC Protein, Human, Recombinant (His)

PP-1G,Serine/Threonine-Protein Phosphatase...

Human E. coli
Serine/Threonine-Protein Phosphatase PP1-Υ Catalytic Subunit (PPP1CC) is a member of the PPP phosphatase family. It is essential for cell division, participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1CC colocalizes with SPZ1 in the nucleus, with URI1 at mitochondrion, Rapidly exchanges between the nucleolar, nucleoplasmic and cytoplasmic compartments. As a cofactor, PPP1CC binds one iron ion and one manganese ion per subunit.. In addition, PPP1C...
TMPJ-01261 PPP1R14A Protein, Human, Recombinant (His)

17 kDa PKC-Potentiated Inhibitory Protein of PP...

Human E. coli
Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase. PPP1R14A is the inhibitor of PPP1CA. When phosphorylated, PPP1R14A has over 1000-fold higher inhibitory activity, creating a molecular switch for regulating the phosphorylation status of PPP1CA su...
TMPY-02767 TPP1 Protein, Human, Recombinant (His)

tripeptidyl peptidase I,CLN2,TPP-1,SCAR7,G...

Human Baculovirus Insect Cells
TPP1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.7 kDa and the accession number is AAH14863.1.
TMPH-01948 PPP1R3G Protein, Human, Recombinant (His & Myc)

PPP1R3G,Protein phosphatase 1 reg...

Human E. coli
Glycogen-targeting subunit for protein phosphatase 1 (PP1). Involved in the regulation of hepatic glycogenesis in a manner coupled to the fasting-feeding cycle and distinct from other glycogen-targeting subunits. PPP1R3G Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 45.5 kDa and the accession number is B7ZBB8.
TMPJ-00528 PPP1R1A Protein, Human, Recombinant (His)

PPP1R1A,I-1,IPP...

Human E. coli
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by cal...
TMPK-00854 ENPP1 Protein, Human, Recombinant (C-His)

M6S1,E-NPP 1,PCA1,PDNP

Human HEK293 Cells
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413.
TMPH-01947 PPP1R15A Protein, Human, Recombinant (His)

Growth arrest and DNA damage-inducible protein GADD34,Protei...

Human E. coli
PPP1R15A Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-05215 TPP1 Protein, Mouse, Recombinant (His)

TPP-1,TPP-I,tripeptidyl peptidase...

Mouse Baculovirus Insect Cells
TPP1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.9 kDa and the accession number is O89023.
TMPK-00852 ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated

E-NPP 1,NPPase,PC1,N...

Human HEK293 Cells
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 98.29 kDa and the accession number is P22413.
TMPJ-01207 UPP1 Protein, Human, Recombinant (His)

UPP1,Uridine Phosphorylase 1,U

Human E. coli
Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine c...
TMPJ-00984 INPP1 Protein, Human, Recombinant (His)

IPP,IPPase,Inositol Polyphosphate 1

Human HEK293 Cells
Inositol Polyphosphate 1-Phosphatase (INPP1) is a member of the inositol monophosphatase family. INPP1 is widely expressed in tissues, with highest expression levels observed in the pancreas and kidney. INPP1 is inhibited by Li+. Removing the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. INPP1 is involved in signal transduction and phosphatidylinositol signaling pathway.
TMPY-01854 DPP10 Protein, Human, Recombinant (His)

DPPY,DPRP3,DPRP-3,DPL2,dipeptidyl-peptidase 1

Human HEK293 Cells
Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein which belongs to thepeptidase S9B family.DPPIV subfamily. It may modulate cell surface expression and activity of the potassium channels KCND1 and KCND2. DPP1 / DPRP3 has no detectable protease activity, most likely due to the absence of the conserved serine residue normally p...
TMPJ-01390 MINPP1 Protein, Human, Recombinant (His)

3,4,5)-Tetrakisphosphate 3-Phosphatase,2,5)P(4) 3-Phosphatas...

Human HEK293 Cells
Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and re...
TMPK-00853 ENPP1 Protein, Human, Recombinant (N-His)

PDNP1,NPP1,NPPase,PCA

Human HEK293 Cells
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (N-His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413.
TMPK-00781 ENPP1 Protein, Mouse, Recombinant (His)

ENPP1,PC1,PCA1ARHR2,PCA<...

Mouse HEK293 Cells
Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 95.99 kDa and the accession number is P06802-1.
TMPJ-00870 NCK1 Protein, Human, Recombinant (His)

SH2/SH3 Adaptor Protein NCK-α,SH2/SH3 Adaptor Protein NCK-Al...

Human E. coli
Cytoplasmic Protein NCK1 (NCK1) is a cytoplasmic protein that contains one SH2 domain and three SH3 domains. NCK1 is a member of the adapter family, which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. NCK1 maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. NCK1 plays a role in the DNA damage response, but not in the detection of the damage by ATM/ATR. It is also involved in transducing...

重组蛋白

PPP1CA Protein, Canine, Recombinant (His & Myc)
Cat.No: TMPH-00499
Species: Canine
Expression System: E. coli
PPP1CB Protein, Human, Recombinant (His)
Cat.No: TMPH-02098
Species: Human
Expression System: E. coli
PPP1CC Protein, Human, Recombinant (His)
Cat.No: TMPJ-00944
Species: Human
Expression System: E. coli
PPP1R14A Protein, Human, Recombinant (His)
Cat.No: TMPJ-01261
Species: Human
Expression System: E. coli
TPP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02767
Species: Human
Expression System: Baculovirus Insect Cells
PPP1R3G Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01948
Species: Human
Expression System: E. coli
PPP1R1A Protein, Human, Recombinant (His)
Cat.No: TMPJ-00528
Species: Human
Expression System: E. coli
ENPP1 Protein, Human, Recombinant (C-His)
Cat.No: TMPK-00854
Species: Human
Expression System: HEK293 Cells
PPP1R15A Protein, Human, Recombinant (His)
Cat.No: TMPH-01947
Species: Human
Expression System: E. coli
TPP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05215
Species: Mouse
Expression System: Baculovirus Insect Cells
ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00852
Species: Human
Expression System: HEK293 Cells
UPP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01207
Species: Human
Expression System: E. coli
INPP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00984
Species: Human
Expression System: HEK293 Cells
DPP10 Protein, Human, Recombinant (His)
Cat.No: TMPY-01854
Species: Human
Expression System: HEK293 Cells
MINPP1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01390
Species: Human
Expression System: HEK293 Cells
ENPP1 Protein, Human, Recombinant (N-His)
Cat.No: TMPK-00853
Species: Human
Expression System: HEK293 Cells
ENPP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00781
Species: Mouse
Expression System: HEK293 Cells
NCK1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00870
Species: Human
Expression System: E. coli
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