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Search Results for " polq "

Targets Recommended: Others

1

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T84770	PolQi2	Others	Others
	PolQi2 抑制了 Polθ 的解旋酶活性，同时提高了多种基因座及细胞系中的基因编辑精度。

化合物

Cat.No: T84770

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01238	POLQ Protein, Human, Recombinant (His) DNA polymerase eta,POLQ,DNA polymerase theta	Human	Baculovirus Insect Cells
	DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul...
TMPH-01237	POLQ Protein, Human, Recombinant (E. coli, His) DNA polymerase eta,POLQ,DNA polymerase theta	Human	E. coli
	DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul...
TMPH-01431	HELQ Protein, Human, Recombinant (His & Myc) Mus308-like helicase,POLQ-like helicase,HELQ,Helica...	Human	E. coli
	Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase. Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2-mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links. HELQ Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 4...
TMPH-01552	IRF1 Protein, Human, Recombinant (GST & His) IRF1,Interferon regulatory factor 1	Human	Baculovirus Insect Cells
	Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired imm...

重组蛋白

POLQ Protein, Human, Recombinant (His)

Cat.No: TMPH-01238

Species: Human

Expression System: Baculovirus Insect Cells

POLQ Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01237

Species: Human

Expression System: E. coli

HELQ Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01431

Species: Human

Expression System: E. coli

IRF1 Protein, Human, Recombinant (GST & His)

Cat.No: TMPH-01552

Species: Human

Expression System: Baculovirus Insect Cells

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