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Search Results for " pmi "

Targets Recommended: Mitophagy

3

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T13809	P62-mediated mitophagy inducer PMI	Mitophagy	Autophagy
	P62-mediated mitophagy inducer (PMI) 是一种线粒体自噬调节剂，能激活线粒体自噬，可在缺乏完整功能的 PINK1/Parkin 通路的细胞中保留活性。
T83641	HNPMI	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	HNPMI 是一种 EGFR 抑制剂，诱导 CRC 细胞的G0/G1 期停滞结直肠癌，可调节与细胞凋亡相关的酶，可促进细胞凋亡，可用于研究结直肠癌。
T60352	ML089	Others	Others
	ML089 (CID-22416235) 是一种可口服且具有有效性、选择性的磷酸甘露糖异构酶 (PMI) 抑制剂，对其他 PMI 直系同源物也具有潜在的抑制作用。ML089 是一种具有膜渗透性的探针，可用于研究Ia 型先天性糖基化障碍(CDG-Ia)。

化合物

P62-mediated mitophagy inducer

Cat.No: T13809

Synonym: PMI

Target: Mitophagy

Cat.No: T83641

Target: Apoptosis, EGFR

Cat.No: T60352

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03611	PMM2 Protein, Human, Recombinant (His) CDG1a,phosphomannomutase 2,PMM2,CDGS,CDG1,PMI,P...	Human	E. coli
	Phosphomannomutase 2, also known as PMM2 and CDG1, belongs to the eukaryotic PMM family. Phosphomannomutase 2 catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mannose 1-phosphate is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. GDP-mannose can transfer its small sugar molecule called mannose to the growing oligosaccharide chain. Once the correct number of small sugar molecules are linked together to form the oligosaccharide, it c...
TMPH-03140	Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His) Plasmepsin I,Aspartic hemoglobinase I,Plasmepsin 1,PMI	Plasmodium falciparum	E. coli
	During the asexual blood stage, catalyzes the initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation; specifically cleaves between Phe-33 and Leu-34 of Hb alpha-chain. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable). Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.0 k...
TMPH-03141	Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (His & Myc) Plasmepsin II,Aspartic hemoglobinase II,PMII,Plasme...	Plasmodium falciparum	Baculovirus Insect Cells
	During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable). Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predict...
TMPH-03142	Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc) PMII,PfAPD,Plasmepsin 2,PfPM1,Aspartic hemoglobinas...	Plasmodium falciparum	E. coli
	During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable). Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. T...

重组蛋白

PMM2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03611

Species: Human

Expression System: E. coli

Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His)

Cat.No: TMPH-03140

Species: Plasmodium falciparum

Expression System: E. coli

Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (His & Myc)

Cat.No: TMPH-03141

Species: Plasmodium falciparum

Expression System: Baculovirus Insect Cells

Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-03142

Species: Plasmodium falciparum

Expression System: E. coli

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